Objective:To investigate the relationship between physical self-esteem and overall self-esteem in the influence of physical activity on aggressive behavior among school college students.Methods:The Physical Activity Exercise Rating Scale,the Physical Self-Esteem Scale for College Students,the Self-Esteem Scale and the Chinese Aggressive Behavior Scale were used to investigate 950college students in school,and chain mediation test and Bootstrap analysis were applied.Results:（1）Individuals who participated in a moderate amount of physical activity had significantly lower levels of aggressive behavior than those who participated in a small amount of physical activity（F=2.762,P＜0.01）,and those who participated in a large amount of physical activity had significantly higher levels of physical self-esteem and overall self-esteem than those who participated in a small amount of physical activity（F=3.275.P＜0.01;F=4.261,P＜0.01）.（2）Physical activity was significantly and positively correlated with physical self-esteem（r=0.314,P＜0.01）and overall self-esteem（r=0.124,P＜0.01）,and significantly and negatively correlated with aggression and its four dimensions;Physical self-esteem was significantly and positively correlated with overall self-esteem（r=0.108,P ＜0.01）,and significantly and negatively correlated with aggression（r=-0.038,P＜0.01）and its four dimensions;overall self-esteem was significantly and negatively correlated with aggressive behavior（r=-0.258,P＜0.01）and its four dimensions.（3） The analysis of mediating effects showed that physical self-esteem and overall self-esteem partially mediated the effects of physical activity and college students’ aggressive behavior,respectively,and the mediating effects consisted of three paths: "physical activity→physical self-esteem →aggressive behavior," "physical activity→ overall self-esteem →aggressive behavior", "physical activity→ physical self-esteem → overall self-esteem → aggressive behavior",and the effect sizes of these three pathways were 57.72%,40.65%,and 1.63%,respectively.Conclusion:Participating in moderate level of physical activity amount is more helpful to reduce college students’ aggressive behavior;Participating in a large amount of physical activity amount can improve college students’ physical self-esteem and overall self-esteem;Physical activity can not only directly affect college students’ aggressive behavior,but also further reduce individual aggressive behavior level by promoting physical self-esteem and overall self-esteem.

运用文献资料、对比研究与数理统计法,对第32届东京奥运会中国体育代表团获奖项目分布和运动员特征进行分析.结果表明:基础项目进步明显,集体球类项目实力薄弱,传统优势项目继续保持胜势;潜优势项目夺金面拓宽;参赛男女运动员比例超过1:2,男性奖牌贡献率高于女性;获奖运动员南北地域分布均匀,东西差异明显.建议发挥新型优势,开拓薄弱项目市场化,调整男女参赛比例;明确三元体制;构建最优培养体系;重视区域协同发展.

信息技术的高速发展为高校公共体育教育提供了技术支持与思维引领,教学方式与教学体系的创新能够带给学生全新的学习体验.混合式教学模式将传统课堂教学与现代网络学习有效整合后,形成了线上线下高效交融的立体教学网络,在传统教学难题得到有效破解的同时更好地满足了学生的个性化需求.本文研究借助微信平台搭建篮球选项课混合教学模式,通过实践教学应用探究混合式学习效果,结果显示,学生的篮球能力素养与篮球运动兴趣同步提升,混合式学习获得了积极教学收获.

以341名初中生和343名高中学生为研究对象,采用问卷调查的方法,分析了体育教师自主性支持,坚毅人格和学校幸福感之间的关系.结果表明:1)体育教师自主性支持对学生的坚毅品质具有积极的正向(+)影响;2)学生的坚毅品质对其学校幸福感具有积极的正向(+)影响;3)学生感知的体育教师自主性支持对学校幸福感具有积极的正向(+)影响;4)坚毅品质在体育教师自主性支持和学校幸福感之间发挥部分中介作用.

本文运用文献资料法、归纳总结法等研究方法,明确了"课内外一体化"教学模式及其优势,分析了高中篮球教学现状,提出了高中篮球教学"课内外一体化"教学模式构建策略.

目的:探讨Straub Aspirex机械性血栓清除术(PMT)联合导管接触性溶栓治疗(CDT)对下肢深静脉血栓(DVT)的有效性和安全性.方法:回顾性分析郑州大学第一附属医院血管外科2019-01-2021-08期间66例下肢DVT的临床资料,其中采用PMT+CDT联合治疗33例(PMT+CDT组),单纯CDT治疗33例(CDT组).分别记录两组的肢体消肿率、血栓清除率、并发症、尿激酶应用剂量、住院时间、住院花费以及随访过程中Villalta评分与血栓复发情况等的差异.结果:PMT+CDT组与CDT组的临床成功率无统计学差异(100％vs 93.48％,P＞0.05).术后PMT+CDT组较CDT组大腿消肿率(63.7±19.3％vs 34.7±17.7％)以及小腿消肿率[65.60(47.70-79.20)％vs 42.50(25.00-64.60)％]更高,差异具有统计学意义(P＜0.01).同时 PMT+CDT 组血栓清除率更高[82.60(75.00-100.00)％vs 65.20(52.70-77.50)％,P＜0.01],尿激酶使用量更低[(322.60±244.20)×104U vs(552.00±193.00)×104U,P＜0.01],住院时间更短[12.60(11.00-14.50)天 vs 15.70(12.00-18.50)天,P＜0.05],但住院费用更高[986 288.30(3 265.30-111 681.20)元 vs 67 301.70(60 768.10-79 575.70)元,P＜0.01].两组出血事件差异无统计学意义(P＞0.05).在随访期内,PMT+CDT组和CDT组分别有2例和7例发生血栓后综合症(PTS),差异无统计学意义(P＞0.05),但PMT+CDT组Villalta评分低于CDT组[1.55(0.50-2.00)分 vs 3.09(1.50-4.00)分,P＜0.05].PMT+CDT 组再狭窄发生率少于 CDT 组(0％vs 15.15％,P＜0.05).结论:PMT联合CDT与单纯CDT治疗DVT均具有良好的疗效和安全性.前者在血栓溶解率、肢体消肿率、尿激酶使用量以及住院时间等方面优势明显,再狭窄发生率也更低,值得推广应用.

基于花炮项目的发展现状、历程和经验,发展与创新民族体育项目,必须打造民族体育项目精品赛事活动,激发全民参与热情;挖掘民族体育项目发展文化动因,促进项目传承;重视民族体育项目多渠道宣传,夯实群众基础.

Palatal mesenchymal cell proliferation is essential to the process of palatogenesis, and the proliferation of mouse embryonic palate mesenchymal (MEPM) cells is impacted by both all-trans retinoic acid (atRA) and the TGF-β/Smad signaling pathway. The long non-coding RNA (lncRNA) MEG3 has been shown to activate TGF-β/Smad signaling and to thereby regulate cell proliferation, differentiation, and related processes. Herein, we found that atRA treatment (100 mg/kg) promoted Meg3 upregulation in MEPM cells, and that such upregulation was linked to the suppression of MEPM cell proliferation in the context of secondary palate fusion on gestational day (GD) 13 and 14. Moreover, the demethylation of specific CpG sites within the lncRNA Meg3 promoter was detected in atRA-treated MEPM cells, likely explaining the observed upregulation of this lncRNA. Smad signaling was also suppressed by atRA treatment in these cells, and RNA immunoprecipitation analyses revealed that Smad2 can directly interact with Meg3 in MEPM cells following atRA treatment. Therefore, we propose a model wherein Meg3 is involved in the suppression of MEPM cell proliferation, functioning at least in part via interacting with the Smad2 protein and thereby suppressing Smad signaling in the context of atRA-induced cleft palate.

目的 观察下肢深静脉血栓(LDVT)患者发病特点及红细胞各项指标的分布情况,探讨红细胞与血栓解剖位置的关系.方法 收集郑州大学第一附属医院2016年1月-2016年12月1 421例诊断LDVT患者,根据血栓的解剖位置分为三组,回顾性收集并分析红细胞相关指标的数据.结果 下肢静脉血栓患者总体偏向中老年(60.0±15.2岁),无论是B组(周围型除外孤立性肌间静脉血栓)与A组(肌间静脉血栓)比较,还是C组(中央型+混合型)与A组比较,回归分析显示年龄越大,患者越倾向于肌间静脉血栓(OR值分别为0.979和0.964,95％CI分别为0.970,0.988,0.954,0.974);B组与A组相比,女性患者更倾向于肌间静脉血栓(OR值为1.666,95％CI为1.286,2.158);红细胞相关指标在三组之间无明显统计学差异(P＞0.05),仅血红蛋白方面,A组和B组明显高于C组(P＜0.05),但在对三组进行回归分析时,结果显示Hb无明显统计学差异(P＞0.05).结论 红细胞相关指标在三组间无明显统计学差异;结合三组间数据对比及回归分析结果,可见高龄女性患者,出现下肢肿胀或疼痛,应警惕下肢肌间静脉血栓形成的可能.

目的:评估俯卧位超声引导腘动脉穿刺入路治疗复杂股浅动脉慢性闭塞性(CTO)病变的安全性和有效性.方法:回顾性分析2016年1月至2019年1月采用俯卧位超声引导腘动脉逆行穿刺入路进行血管腔内治疗的复杂股浅动脉CTO病变患者的临床资料.符合条件的126例患者中男性81例,女性45例,平均年龄(65.3±9.7)岁,共178条股浅动脉,平均闭塞长度(17.3±7.8)cm.所有患者均采用俯卧位超声引导腘动脉穿刺入路,导丝配合导管逆向开通股浅动脉闭塞段,必要时行对侧腘动脉穿刺使用SAFARI双向开通技术,建立轨道导丝并全身肝素化后行球囊并支架置入.结果:178条股浅动脉CTO病变中172条血管开通成功,技术成功率96.6％.术后踝肱指数(ABI)较术前明显提高(0.93±0.21 vs 0.38±0.19,P<0.01),提高幅度>0.15;随访1年ABI值均明显高于术前(P<0.05).191处穿刺点共31处(16.2％)发生并发症,均不需要手术或介入处理.随访1年累计一期通畅率82.8％,辅助通畅率93.1％,二期通畅率97.4％.结论:俯卧位超声引导腘动脉穿刺入路治疗复杂股浅动脉CTO病变安全有效,可作为股动脉的替代入路选择.

为了解不同身体负荷下足底压力分布特征及肌电特征,运用表面肌电测量仪、配套三维测力台和Vicon Nexus运动捕捉系统等对受试者进行了测试.研究结果表明:负载质量存在一个使足底压力逐渐趋于不变的阈值.通过人体保护补偿机制,高于阈值的负荷质量产生的压力,被肢体动作迅速分散,增加前后方向的冲力,降低垂直方向的地面反作用力.但同一肌肉的有效放电值(RMS)在不同运动形式下,随负荷质量增大可能出现不同的变化趋势.如胫骨前肌RMS在行走过程中,随负荷质量增加有少量增大趋势,跑步则是随负荷质量增大而显著降低.

运用文献资料法与逻辑分析法等,界定城市社区体育设施多链融合的概念,分析现实困境并提出发展策略.城市社区体育设施多链融合指的是推动社区体育设施的场地、空间布局、互动信息等多个要素的链接,涉及供需链、空间链、创新链、价值链之间的衔接与匹配.现实困境:供需链聚合性差,融合机制失灵导致孤链形态;创新链驱动不足,模式固化导致社会资本流入意愿不强;空间链整合缺失,服务机制不完善制约供给质量.发展策略:建立多要素聚合的融合机制,形成对接居民需求的网状供给结构链;创新构建社区"体育+"投资环境,促使社会资本与创新链形成有机衔接;将区块链技术融入多链服务体系,构建一体化服务功能的空间链.

采用文献研究法和实地调查法对2018年平昌冬奥会举办愿景、举办效应进行分析,并提炼举办效应特征,以期为我国2022年北京冬奥会的顺利举办作理论参考.2018年平昌冬奥会举办效应特征是:1)建设"代替森林",对平昌新建冬奥会场馆进行"绿色建筑"认证;2)促进朝韩和解与世界和平;3)从精神层面到物质层面传播韩国传统文化;4)将社会效益与经济效益相结合.得到启示:1)以"绿色"与"可持续发展"理念促进2022年北京冬奥会效益;2)坚持和平与发展理念,将中国塑造为"世界和平的建设者";3)以多种形式促进中华优秀传统文化与奥林匹克文化融合;4)发展体育产业及其相关产业,助力"体育强国"建设.

体育教育专业核心课程实施"课程思政",对培养学生成为一名具有高度的师德情怀、适应时代和教育发展需求的复合型人才有着重大意义.目前,体育教育专业课程实施课程思政还存在教师思想政治意识弱、能力不足、课程思政元素挖掘不充分、课程思政思实施方法单一和学生参与度低等问题.因此,提出体育教育专业核心课程实施课程思政的策略有提升教师的政治觉悟和树立自己独有的思想政治理念、研究课程教学内容特点,充分挖掘体育教育核心课思想政治元素、多专业教师组建课程思政团队、充分调动学生参与思想政治活动、注重学生情感体验与感悟、充分发挥课堂教学的作用,并搭建师生思想政治共享平台,实现资源共享、建立"教师+学生"的核心专业课程思政考核评价体系等.

2,3,7,8-Tetrachlorobenzo-p-dioxin (TCDD), one of the key endocrine disruptors, has been shown to cause reproductive and developmental disorders. Our previous studies have primarily focused on TCDD induced impairment of ovarian follicular development in female F1 rats. It is unknown whether TCDD exposure will interfere with follicular development by altering mRNA expression of anti-MUllerian hormone (AMH) and AMH receptor type II (AMHR2) in the ovary. In the present study, pregnant Sprague Dawley rats were treated with TCDD (100 or 500 ng/kg body weight) dissolved in a corn oil vehicle by gavage from gavage from gestational days (GD) 8-14, while the control group received solely corn oil. The F1 rats were mated with unexposed males for the F2 generation, while another portion of the female offspring (F2) were mated for the F3 generation. Serum AMH levels and ovarian AMH/AMHR2 mRNA expression in the adult female offspring (F1, F2 and F3 generations) were measured. Follicle count and granulosa cell apoptosis were evaluated in the F2 and F3 generations. The results showed that in the F2 generation, TCDD exposure affected the number of primordial follicles, secondary follicles, and corpora lutea. It also increased serum AMH concentration and the apoptosis rate of granulosa cells. These results might be associated with the upregulation of AMH/AMHR2 mRNA expression in the ovary. In conclusion, TCDD exposure reduced the ovarian reserve in rats and inhibited follicular development in adult female offspring, an effect that persisted for multiple generations. The altered AMH and AMHR2 mRNA expression may contribute to the observed adverse effects.

目的 观察经腘动脉入路逆行开通股浅动脉慢性闭塞性(chronic total occlusion,CTO)病变的安全性和有效性.方法 回顾性分析2012年3月至2019年3月本院收治的股浅动脉CTO病变患者的病历及1年随访资料.经传统股动脉(femoral artery,FA)入路顺行开通为FA组(2265例),俯卧位经腘动脉(popliteal artery,PA)入路逆行开通为PA组(216例).结果 两组技术成功、支架置入及围手术期(30 d)不良事件(死亡、动脉夹层、远端栓塞及穿刺相关并发症)发生率差异无统计学意义.FA组CTO设备使用率、手术操作及透射时间均明显高于PA组(P<0.05).1年随访一期通畅率、保肢生存率及主要不利于心脑血管事件(心肌梗死、脑卒中及任何原因的死亡)发生率差异均无统计学意义.结论 相比传统股动脉入路经腘动脉入路治疗股浅动脉CTO病变同样安全有效,可作为股动脉入路的替代选择.

对我国的非物质文化遗产保护进行了研究.目前我国非物质体育文化遗产保护面临的问题有:现代文明的冲击,开发性破坏显著,重“申遗”轻“保护”,跟踪评估与责任追究缺失.从审计层面提出了非物质体育文化遗产保护的对策:强化审计队伍,深化思想认识,完善跟踪评估与责任追究体系,优化监督环境.