优质护理是在常规护理措施的基础上进一步完善综合的护理方式,主要包括基础护理、生活干预、心理辅导、出院后随访和护理示教等,针对慢性胃炎患者进行有效合理的护理措施,重视患者情绪变化、个人生活习惯的调整,以提高治疗配合度,保证治疗有效,促进疾病恢复.

目的 探讨基于微信平台的延续性护理对哮喘患者疾病认知和自我控制情况的影响.方法 将72例确诊的支气管哮喘患者随机分为对照组(35例)和观察组(37例).对照组进行常规护理干预,观察组在此基础上实施基于微信平台的延续性护理.比较两组的干预效果.结果 观察组疾病认知、遵医行为、焦虑、哮喘控制情况均优于对照组(P<0.05).结论 基于微信平台的延续性护理能有效提高患者对哮喘防治知识的知晓度,并显著改善哮喘患者的治疗效果.

目的探讨呼吸衰竭患者紧急情况下应用气管镜引导进行气管插管的配合与护理方法。方法对50例呼吸衰竭患者采用气管镜引导气管插管，同时给予熟练护理配合，正确采取体位，掌握操作中常见并发症及处理措施，严密观察患者反应，给予心电监护，向家属做好解释及心理护理，备齐抢救用物，预防各种不良反应等。结果采用气管镜引导行气管插管本组患者50例全部插管成功，其中48例接呼吸机辅助呼吸后病情好转，另2例插管后循环衰竭死亡。结论气管镜引导进行气管插管作为急、慢呼吸衰竭患者抢救生命的一种方法，在临床上不断发展成熟，特别对于困难气管插管患者[1]，能有效缩短抢救时间，挽救患者生命。临床需护士严格把握适应症、进行熟练配合、严密监护和积极防治各种并发症，以保证在最短时间内抢救成功，保证患者安全。

目的 观察甲状腺功能亢进症(甲亢)并糖尿病(DM)患者的甲状腺激素、血糖、血脂变化,探讨甲亢确诊前后胰岛素控制血糖的剂量及调整方法.方法 选择甲亢并DM患者24例(观察组)、甲亢继发DM患者26例(对照组),检查两组的甲状腺激素(FT4、FT3、TSH)、血糖(FPG、2 hPG、HbA1c)、血脂(TC、TG)水平,比较观察组确诊甲亢前后的胰岛素用量.结果 观察组FT3、FT4水平明显低于对照组(P＜0.05或＜0.05),TC、TG、FPG、2hPG水平均明显高于对照组(P＜0.05或＜0.01).观察组确诊甲亢前每日胰岛素用量为(34.5 ±6.1)U,确诊甲亢后血糖指标明显升高(P均＜0.01),调整胰岛素用量至血糖达标时的每日胰岛素用量为(57.8±8.5)U,较前明显增加(P＜0.05).结论 甲亢并DM与甲亢继发DM的临床表现不同,其甲状腺激素、血糖、血脂水平比较均有统计学差异.甲亢并DM患者在确诊甲亢后血糖指标明显升高,胰岛素用量较确诊甲亢前明显增加.

Objective To investigate the effect of Heat Shock Protein 90 (HSP90) inhibitor 17-DMAG on the proliferation and apoptosis of human hepatic satellite cell line LX2 cells in vitro. Methods The LX2 cells were cultured in vitro. The inhibitory effect of 17-DMAG on LX2 cells in different time and concentration was assayed by MTT assay. Flow cytometry was used to test the apoptosis of 17-DMAG interfered cells. The expression of α-SMA protein was detected by Western blot and compared with control group. Results The results showed that 17-DMAG could inhibit the growth of LX2 cells in a time and concentration dependent manner (P<0.01). With the increase of concentration of 17-DMAG, and the time interfered, the amount of live cells decreased. The apoptosis effect of 17-DMAG on LX2 cells was confirmed by flow cytometry, compared with control group, the apoptosis rate of the interfered group increased obviously(P<0.01). Western blot showed that 17-DMAG could decreased the expression of α-SMA. Conclusion 17-DMAG could inhibit the proliferation of LX2 cells in a concentrate and time dependent manners by inducing their apoptosis, and later decrease the expression ofα-SMA to inhibit the production of collagen.

食管胃底静脉曲张破裂出血是导致肝硬化患者最常见的并发症，患者多突然发生呕血和（或）便血，常因大量出血引起出血性休克[1]，危急生命。经过积极抢救虽可幸免于难，但是反复出血会给患者及家属增加痛苦和经济负担，由于上消化道出血与日常生活密切相关，很多出血是患者吃出来或累出来的，因此，对肝硬化并发上消化出血的患者进行健康教育，加强患者预见性意识，采取预见性护理措施，可以减少出血机会，降低死亡率。

<正>类癌是临床上较少见的一种恶性肿瘤,它起源于胚胎时期的神经嵴嗜银细胞,亦称嗜银细胞瘤,属于内分泌肿瘤的一种。类癌发病率低,约占整个消化道恶性肿瘤的0.4%~1.8%。我院诊治十二指肠降部类癌1例,现报告如下。1临床资料病人,女,48岁,因反复上腹隐痛、饱胀不适3~4年入院。8个月前病人曾于外院行胃镜检查,诊断为"慢性浅表萎缩性胃炎",经相应治疗(具体用药及疗程不详),病情时有反复。6个月前上述症状加重,又于我院复查胃镜,镜下除胃窦部黏膜轻度充血肿胀外,尚于十二指肠降段发现一大小

Objective To observe the clinical effect of treating diabetic nephropathy with Shengqidihuang decoction combined with metformin. Methods 54 cases with diabetic nephropathy were randomly divided into two groups by means of random number table. Both groups were given diabetic routine treatment. The control group was treated with metformin, 0.25 mg each time, three times a day, based on the diabetic routine treatment for 8 weeks, and the treatment group was treated with Shengqidihuang decoction, once a day, 4 weeks as a course, continuously treated for 2 courses based on the control group. 24 h urinary protein (24hUAE) , serum creatinine (SCr) , blood urea nitrogen (BUN) and fasting blood glucose (FBG) were detected before and after the treatment. The clinical effect was observed between the two groups after the treatment. Results The total effective rate of the treatment group and the control group was 85.2% and 66.7% respectively, showing a significant difference (λ2=3.376, P<0.05). Compared with the control group, 24 hUA ,SCr, BUN and FBG in the treatment group decreased significantly (λ2=4.231, P<0.05) after the treatment.24hUAE, SCr, BUN and FBG decreased significantly after the treatment, especially in the treatment group, also showing a significant difference (λ2= 3.754, P<0.05). Conclusion The therapy of mefformin combined with Shengqidihuang decoction on diabetic nephropathy was better than metformin only.

2004年7月～2005年12月,我们对气管插管患者试行放气囊置胃管法,效果满意.现报告如下.

2003年3月-2004年10月,我科对36例无创通气患者采用纱布和一次性手套改良口鼻面罩,使无创机械通气取得良好效果,现报道如下.

临床常用的血气分析采血部位有股动脉、肱动脉、桡动脉及足背动脉.2003年1月～2005年1月,我科从桡动脉采血做血气分析158例,取得满意效果.现将方法与体会报告如下.

胸腔穿刺是内科治疗自发性气胸、胸腔积液的主要技术.患者往往需要反复穿刺,其损伤和痛苦较大,并增加感染的机会.我科2002年1月～2003年4月对23例胸腔积液患者采用锁骨下静脉置管针进行胸腔闭式引流疗效好,创伤小、安全性高,患者易于接受,现报告如下.