Objective It is to investigate the influence of invigorating spleen and tonifying kidney on sperm quality related indicators of male infertility patients with non severe asthenospermia and pregnancy outcomes in their spouses after intrauterine insemination ( IUI) by husband .Methods A total of 60 male infertility patients with spleen and kidney deficiency type were collected and randomly divided into two groups with 30 cases in each.The patients were treated by oral administration with Chinese medicine of invigorating spleen and tonifying kidney in Group A , 12 weeks for one course of treatment , but did not re-ceive any intervention in Group B .Before and after treatment , the changes of sperm quality indexes were detected by computer assisted sperm analysis (CASA), sperm morphology and sperm DNA integrity detection , and the pregnancy outcome in their spouses after IUI was followed up .Results After treatment of 12 weeks, the sperm motility and forward motile sperm ratio were significantly higher compared with before treatment in Group A (P<0.05); there was no significant difference in semen vol-ume, sperm concentration , sperm morphology , sperm DNA integrity and sperm motility parameters before and after treatment in the two groups (all P<0.05); the clinical pregnancy rate and cumulative pregnancy rate and live birth rate of Group A were more higher than those of B group , but there was no significantly difference (P>0.05).Conclusion The method of in-vigorating spleen and tonifying kidney combined with IUI in the treatment of male patients with non severe asthenospermia can improve the sperm motility and forward movement speed , and it can also improve the pregnancy outcome of IUI .

Objectives:To investigate the reproductive health status of female at reproductive age in the department of gynecology and reproductive medicine.Methods:A questionnaire survey was conducted among 240 female patients in the department of gynecology and reproductive medicine.Results:Premarital sex in married and unmarried women accounted for 78.33％ and the ratio of unmarried women who had premarital sex (44.58％) were higher than that of married women (33.75％) respectively.Women with more than once miscarriage experience accounted for 62.5％,and condoms were most commonly used contraceptive methods,accounting for 43.75％.Women who had symptoms of genital tract infection accounted for 53.33％ and women who hoped to consult reproductive health problem through the hospital department of gynecology or reproductive medicine accounted for 54.58％.Most wanted consulting problem was reproductive health problems,accounting for 39.58％.Women who concerned about contraception problems accounted for 16.25％.Conclusion:Most young married and unmarried women at childbearing age have the experience of premarital sex,more than once experience of abortion and reproductive tract infections.Strengthening the propaganda of contraceptive knowledge and prevention knowledge of reproductive tract infection is beneficial to improve the reproductive health of the young women.

Objective To explore the effect of invigorating splcen and kidney methods on the pregnancy outcome of the intrauterine insemination (IUI) in infertile men with asthenospermia.Methods a total of 78 male infertility patients with "spleen and kidney deficiency type" were collected,all cases were randomly allocated into three groups,group A using methods of invigorating spleen and kidney,group B using Antioxidant therapy,and group C as the blank group.There are 26 cases in each group.One course of treatment lasts for 12 weeks.Before and after treatment,the changes of sperm quality index were analyzed by computer assisted sperm analysis (CASA) and sperm morphology.The pregnaucy outcome after IUI was followed up.Results After the treatment,sperm motility and sperm forward movement (PR) difference before and after treatment in group A with was statistically significant (P ＜ 0.05).The differences between patients with semen volume,sperm concentration,sperm morphology and sperm motility parameters before and after treatment in three groups were not statistically significant (P ＞ 0.05).Clinical pregnancy rate and cumulative pregnancy rate and the live birth rate in group A were higher than that of group B and group C,but the difference was not statistically significant (P ＞ 0.05).Conclusion Invigorating spleen and kidney method can improve the sperm motility and forward movement speed of the type of patients for the treatment of male infertility patients with asthenospermia,and it is helpful to improve the pregnancy outcome of the IUI.

目的:观察宫血宁胶囊治疗置环术后月经异常出血的效果.方法:157例随机分成治疗组85例和对照组72例.治疗组用宫血宁2粒口服,1日3次口服;对照组消炎痛25mg、止血敏1.0g、氟哌酸胶囊0.2g,1日3次口服.两组均于月经来潮第1天开始服药,3个周期为一疗程.结果:总有效率治疗组84.71％、对照组70.83％,两组比较差异有统计学意义(P＜0.05).有2例因持续阴道出血而中断IUD使用.结论:宫血宁能改善置环后经量增多、经期延长、经期不规则出血等症状,效果优于西药.

Objective:To explore the causes and related factors of repeated induced abortion in women of childbearing age.Methods:From January 1,2008 to August 31,2010,231 cases undergoing induced abortion in Guangzhou Technical Institute for Population and Family Planning were collected,and then they were divided into single abortion group and repeated abortion group according to the times of abortion.The proportions of age,marital status,pregnancy history,abortion history,delivery modes,and contraceptive methods and their relationships with repeated induced abortion were analyzed.Results:Among 231 cases of induced abortion,112 cases were repeated induced abortion,accounting for 48.5%.Age,marital status,delivery mode,and usage of contraceptives were not associated with repeated induced abortion.Multipara and irregular condom use were associated with repeated induced abortion.Conclusion:Strengthening the contraceptive propaganda in the women of childbearing age and improving the active consciousness of consistent using condom as a contraceptive method are important to reduce the rate of repeated induced abortion among women of childbearing age.

Objective To research the anesthesia effect and safety of Propofol on the tubal ligation with pelvic surgery history.Methods One hundred and thirty one cases of patients with Propofol anesthesia on tubal ligation were retrospectively analyzed,and they were divided into two groups,the groupⅠ: patients with no previous history of pelvic surgery group(89 cases),and the group Ⅱ: patients with history of pelvic surgery(42 cases).All the two groups were given the same medical treatment,and operation time,dose of Propofol,intraoperative and postoperative situation of two groups were compared.Results The operation time and the dose of Propofol in the group Ⅱ were more than that of in the groupⅠ(P < 0.01),twisting limbs during surgery and postoperation pain medication in the group Ⅱ were more than those in the group Ⅰ(P < 0.01).Blood pressure fluctuations in the group Ⅱ changed more than that in groupⅠ.Conclusion The tubal ligation with pelvic surgery history can be successfully implemented under anesthesia with Propofol,but the risk is higher.It is suggested to use the epidural anesthesia or other contraceptive methods.

目的分析妇女取出宫内节育器(IUD)的原因及其相关影响因素。方法收集266例取IUD患者的临床资料,按取环原因分为第一组病理取环组134例,第二组生理取环组132例,分别对两组患者的年龄、孕产史、上环时限、分娩方式和节育器类型等进行分析。结果第一组的年龄小于第二组(P=0.000);第一组的上环年限短于第二组(P=0.000);剖宫产术后发生病理取环率高于顺产(P=0.000),T型环和宫型环发生病理取环比例高于生理取环(P=0.000),金属圆环多以生理因素取环(P=0.000),差异均有统计学意义。结论年龄小、上环年限短多见于病理取环;剖宫产、T型环和宫型环与病理取环有关,金属圆环与生理取环有关。

目的 评价舒芬太尼靶控输注与间断给药或恒速静脉注射相比是否更具优势.方法 随机选择择期行妇科腹腔镜手术的患者60例(ASAⅠ～Ⅱ级),年龄＜50岁,随机分为3组,每组20例,双盲对照观察.全部病例采用舒芬太尼复合丙泊酚全凭静脉麻醉,根据分组要求使用不同的给药方式静脉注射舒芬太尼:舒芬太尼给予负荷量后间断给药维持(组Ⅰ)、舒芬太尼给予负荷量后恒速静脉注射(组Ⅱ)、舒芬太尼靶控输注(组Ⅲ).观察麻醉诱导期、手术中及麻醉苏醒期的血压、心率以及Narcotrend麻醉深度分级及数值的变化;记录术毕停药后患者自主呼吸恢复时间、呼之睁眼时间、拔管时间、定向力恢复时间以及苏醒质量.结果 3组患者在麻醉诱导期、手术中以及麻醉苏醒期10个时点血压和心率组间比较差异均无显著性(P>0.05);3组患者呼吸恢复时间、定向力恢复时间、意识状态恢复差异均无显著性(P>0.05);组Ⅲ睁眼时间及拔管时间均明显短于其他两组(P<0.05).结论 舒芬太尼靶控输注与间断给药或恒速静脉注射相比,苏醒更快,但在维持围术期血流动力学稳定性以及苏醒质量上无明显优势.

OBJECTIVE: To study human telomerase reverse transcriptase(hTERT) mRNA in cervical exfoliated cells from the specimens of normal and cervical cancer(CC),and analyze its relation with clinical or patho-characters and its contribution to clinical diagnosis.METHODS: The real-time fluorescent quantitative reverse transcription polymerase chain reaction(real-time qRT-PCR)was employed to detect the hTERT mRNA positive expression and quantitative levels of HeLa cell strains(the cell group),and of cervical exfoliated cells in 40 cases of CC(the cancer group)and 21 cases of normal or chronic cervicitis(the control group).RESULTS: The positive rate of hTERT mRNA in exfoliated cells from the cancer group and the control group were expressed as 82.5% and 9.5%(P=0.000).The quantitative levels of hTERT mRNA(NhTERT) in them were respectively expressed as 0.327 6-13.782 3 and 0.009 3-0.081 6(P=0.019).All of them indicated statistical significance.In the cancer group,there is relativity between the positive rate of hTERTmRNA and differentiation of CC(r=-0.308,P=0.016),but there is no relativity among age,clinical stages,invasive depth and histological classification.CONCLUSIONS: The positive rate and quantitative levels of cervical exfoliated cells from specimens of CC are more higher than that of the normal cervix.The proceture is recommended for early detection in clinic for diagnosing CC and its prognosis.

Objective To explore the influence of douching therapy with ozone liquid and medication for vagina internal environment.Methods 147 patients with vaginitis were classified into two groups: the ozone douching group and the medical group.The symptom,cleaning value,the pH value,actobacillus of vaginal internal environment in patients were observed before and after treatment.Results Before treatment,there were no significant difference of the vaginal symptom,cleaning value,actobacillus between two groups,but vaginal pH value has obviously declined after treatment,and the difference between two groups has statistical significance.Other index about internal environment also has improved.Conclusion Douching therapy with ozone liquid and medication for vaginal inflammation can decline the pH value,and be benefit for vagina internal environment.

Objective:To explore the psychological and mental health status of women at reproductive age before intrauterine device(IUD) insertion,in order to provide a theoretical and practice basis for better family planning and contraceptive quality service.Methods:Women underwent psychological evaluation with symptom checklist 90(SCL-90),selfrating anxiety scale(SAS) and selfrating depression scale(SDS) before intrauterine device insertion.Results:There was no significant difference between the score of SCL-90 of these women and that of the national norm in somatization and psychosis(P>0.05),while scores of other factors were even lower than those of the national norm(P<0.05).The score of SDS was lower than that of the national norm(P<0.05).And the score of SAS was higher than that of the national norm(P<0.05).Conclusion:IUD insertion was a safe,simple,effective,reversible and acceptable contraceptive measure.While it could induce symptoms of mild anxiety because of the operation may act as a stress source.

Objective:To observe clinical effects of propofol combined with lidocaine or midazolam on prevention of injection pain in patients performing tubal ligation.Methods:A total of 120 patients were randomly divided into three groups.Patients in the control group were injected with 2ml of normal saline;patients in the midazolam group were given intravenously 2ml of midazolam(0.1%);patients in the lidocaine group were given the mixture of 20 ml of propofol(1%)and 2 ml of lidocaine(2%).The VRS score was used to evaluate the pain associated with propofol injection and its effect and security on the anesthesia.Results:The patients in the lidocaine group felt less injection pain than those in the other two groups.Intravenous lidocaine had sedative effects.Conclusion:The use of lidocaine could significantly alleviate the pain due to propofol injection,and reduce the dose of propofol.Patients regained consciousness quickly and had stable vital signs.