文章从教学资源建设、教学方法改革等方面探讨针灸学专题讲座的课程教学改革思路.基于问题的教学方法(PBL)、BOPPPS教学模式各具优势特色,在针灸学专题讲座的课程教学中,根据教学内容交替运用PBL及BOPPPS两种教学模式,对于激发学生学习兴趣、调动学生学习主动性有更好的促进作用,同时有利于培养学生的自主学习能力、沟通表达能力及团队协作精神.
OBJECTIVE To evaluate the efficacy and safety of moxibustion at Baihui (CV20) combined with acupuncture in treatment of cervical vertigo. METHODS From the databases, such as CNKI, VIP, WanFang, CBM, PubMed, Cochrane Library and Embase, the studies of randomized controlled trials (RCTs) on moxibustion at CV20 combined with acupuncture for cervical vertigo were searched from inception to September 15th, 2021. The Cochrane risk of bias assessment tool was utilized to evaluate the quality of the included literature. Using RevMan5.3, Stata12.0 and TSA0.9.5.0 10 Beta software, the Meta-analysis and trial sequential analysis (TSA) were performed. RESULTS Seventeen RCTs with 1 232 patients were included. Meta-analysis showed that in the trial group (moxibustion at CV20 combined with acupuncture), the total effective rate (RR=1.17, 95%CI[1.12, 1.22], P<0.000 1), the curative and remarkably-effective rate (RR=1.28,95%CI[1.20,1.36],P<0.000 1) and the score of cervical vertigo (WMD=2.88, 95%CI[1.87, 3.89], P<0.000 1) were all better when compared with the control group (simple acupuncture or electroacupuncture group). The results of trial sequential analysis indicated that for the cumulative Z-score of each RCT, the Z-curve crossed the conventional test boundary and TSA boundary, which further confirmed the clinical efficacy of moxibustion at CV20 combined with acupuncture on cervical vertigo. CONCLUSION The clinical efficacy of moxibustion at CV20 combined with acupuncture is determined in treatment of cervical vertigo.
目的 观察针刺对2型糖尿病大鼠RNA依赖的蛋白激酶样内质网激酶-增强子结合蛋白同源蛋白(PERK-CHOP)通路、内质网应激的干预作用.方法 选用SPF级雄性SD大鼠80只,除对照组外,其余采用高脂高糖饲料加低剂量链脲佐菌素(STZ)腹腔注射制备STZ-DM大鼠模型.随机分为4组,分别为对照组、模型组、针刺治疗组和药物组.针刺治疗组取后三里、内庭、胰俞进行治疗;药物组:100 mg/kg盐酸二甲双胍灌胃,疗程与针刺治疗组平行;模型组和对照组不做其他任何处理.疗程结束后采用RT-PCR和Western印迹检测各组大鼠胰腺组织的CHOP、PERK的蛋白表达、mRNA的转录水平及电镜下内质网的形态学改变.结果 与模型组比较,针刺治疗组和药物组CHOP、PERK蛋白表达显著下降(P<0.05);电镜下观察模型组内质网极度扩张,而针刺治疗组内质网扩张得到改善.结论 针刺可能通过抑制PERK-CHOP通路来改善胰腺组织中的内质网应激,从而对治疗糖尿病产生一定的作用.
"其来不可逢,其往不可追"体现中医治病因势利导的原则,"因势"为顺应事物发展,"利导"为用治疗手段顺病势而为,强调"给邪以出路".《伤寒论》中,邪气在表者,通过开腠理、调营卫的汗法以驱肌表之邪;邪气阻遏于上焦、病势在上时,可因势利导,用吐法驱邪外出;患者素体阳气偏盛,痰、瘀、饮等实邪聚于肠胃时当用泻法,包含"利小便"和"通大便",使邪从大小便而出.邪气来之有路,必出之有道,开通邪路,使之或随汗、或随吐、或随大小便出,"给邪以出路",从而恢复机体阴阳平衡的状态.
目的:观察调理三焦法穴位埋线对单纯性肥胖患者血脂、血糖代谢的影响.方法:将58例单纯性肥胖症患者随机分成埋线组(28例)、对照组(30例),分别给予调理三焦法穴位埋线治疗和口服西药二甲双胍治疗,观察两组患者治疗前后血脂、空腹血糖水平及血清空腹胰岛素的变化,并计算胰岛素抵抗指数.结果:经过3个月治疗后,两组患者的血脂、空腹血糖水平改善均有统计学意义(均P<0.05),血清空腹胰岛素(FINS)水平、胰岛素抵抗指数均有显著下降(均P<0.05);且埋线组各项指标改善均优于西药组(均P<0.05).结论:调理三焦法穴位埋线有改善肥胖症患者脂质、血糖异常代谢的作用,能改善胰岛素抵抗发病机制,疗效优于二甲双胍,可能是有效治疗肥胖症的方法之一.
《经络腧穴学》是一门汇集了经络腧穴学和刺法灸法学的专业课程,也是针灸推拿学专业的基础课程.本门课作为本学院开展课程思政教学的一次试水点,初步对这门课的课程思政建设进行探讨,本文对这门课的课程思政建设情况进行介绍并试做总结.
本文通过回顾近10年来针灸治疗子宫内膜异位症(Endometriosis,EMs)的相关文献,对EMs发病的病因病机、病理、针灸临床和实验观察进行分析,可以看出针刺疗法、灸法、耳针疗法、穴位敷贴疗法,穴位注射疗法及其联合治疗EMs均具有治疗意义,可确定针灸治疗EMs具有疗效快、复发率低、无不良反应的特点.但系统化、规范化相关研究仍有待进一步完善.
为了解决临床治疗与家庭保健应用中因艾灸器具占地空间大、性能单一、不便调节艾条角度和高度等使用不便问题,研制一款多功能便巧艾灸辅助器十分必要.该文主要介绍一款多功能便巧艾灸辅助器,其设计新颖独到,结构合理简单,简便易操作,安全性高,实用性强,适用于大部分穴位灸治,对部分双穴治疗更具优势,灸治针对性强,极大提高了灸疗效果和灸治效率,有利于艾灸器具的发展与推广.
OBJECTIVE To explore the effect of moxa-cone moxibustion at "Feishu" (BL13) and "Zhongfu" (LU1) on the contents of related inflammatory factors in serum and bronchoalveolar lavage fluid (BALF), and the expression of phosphatidy-linositol-3-kinase (PI3K), retinoic acid related orphan receptor γt (RORγt) and fork/wing helix transcription factor 3 (Foxp3) in lung tissue in asthma mice. METHODS Sixty male Balb/c mice were divided into normal, model, LY294002 (an inhibitor of PI3K, LY), electroacupuncture (EA) and moxa-cone moxibustion (moxibustion) groups (n=12 in each group). The asthma model was established by intraperitoneal injection of ovalbumin sensitization. The mice in the LY group were injected with LY 294002 (7.5 mg/kg) via the tail vein. EA or moxa-cone moxibustion was applied at BL13 and LU1 in the EA or moxibustion group once daily for 2 weeks. The levels of immunoglobulin E (IgE), interleukin-4 (IL-4) and interferon-γ (IFN-γ) in serum and BALF were detected by enzyme-linked immunosorbent assay. The expressions of PI3K, RORγt and Foxp3 in lung tissue were detected by real-time fluorescent quantitative polymerase chain reaction (QRT PCR) and immunohistochemistry. RESULTS Compared with the normal group, the levels of IgE and IL-4 in serum and BALF, the expressions of PI3K and RORγt mRNA and protein in lung tissue were significantly increased (P<0.01), while the levels of IFN-γ, and the expressions of Foxp3 mRNA and protein were significantly reduced (P<0.01) in the model group. Compared with the model group, the levels of IgE and IL-4 in serum and BALF, the expressions of PI3K and RORγt mRNA and protein in lung tissue were significantly decreased (P<0.01, P<0.05), and the levels of IFN-γ in serum and BALF, the expressions of Foxp3 mRNA and protein in lung tissue were significantly increased (P<0.01) in the LY, EA and moxibustion groups. CONCLUSION Moxa cone moxibustion at Shu- and Mu-acupoints of the lung meridian can reduce airway inflammatory reaction and control asthma attacks in asthma mice, which is closely related to its effects in regulating the expressions of RORγt and Foxp3 through PI3K signaling pathway.
目的 观察朱琏"兴奋"Ⅱ型针刺手法治疗慢性咽炎的效果.方法 将60例慢性咽炎患者随机分为观察组和对照组,每组30例,两组均选择肺俞、列缺、肾俞、太渊、中府、太溪、照海、廉泉、足三里穴为治疗穴位,观察组采用朱琏"兴奋"Ⅱ型针刺手法治疗,对照组采用常规针刺手法治疗,两组疗程均为28 d.比较两组患者治疗前后的中医症候积分及治疗后的疗效.结果 治疗后,两组患者咽痛、咽痒、咽部异物感、干咳、咽后壁充血、淋巴滤泡增生评分均低于治疗前,并且观察组各症候评分均低于对照组(均P<0.05);观察组总有效率为86.66%,对照组为70.00%,观察组疗效好于对照组(P<0.05).结论 运用朱琏"兴奋"Ⅱ型针刺手法治疗慢性咽炎可有效地缓解患者临床症状,提高疗效.
OBJECTIVE:To observe the effect of moxa-cone moxibustion at lung's back-shu points and front-mu points on the expression of helper T lymphocyte 17 (Th 17)/regulatory T lymphocyte (Treg) in mice with asthma, and to explore the possible mechanism of moxa-cone moxibustion on asthma. METHODS:Sixty SPF-grade healthy male Balb/c mice were randomly divided into a normal group, a model group, an LY294002 group (LY group), an electroacupuncture (EA) group and a moxibustion group, 12 mice in each group. Asthma model was replicated by using ovalbumin (OVA) sensitization. Except the mice in the normal group, all the mice were intraperitoneally injected with sensitization solution (containing 15 μg of OVA and 30 mg of aluminum hydroxide) on the 1st day, 7th day and 14th day, 0.5 mL per mice; from the 15th day, 1% OVA solution was atomized for 20 min, once a day for 2 weeks; the mice in the normal group was treated with identical operations but with 0.9% sodium chloride solution. The mice in the LY group were treated with injection of LY294002 at tail vein on the 13th day, 14th day and 15th day. At the beginning of the 15th day, The mice in the EA group were treated with EA at "Feishu" (BL 13) and "Zhongfu" (LU 1) with disperse-dense wave, frequency of 2 Hz/20 Hz, intensity of 1 mA, 15 min each time, once a day for 2 weeks. The mice in the moxibustion group was treated with moxa-cone moxibustion at "Feishu" (BL 13) and "Zhongfu" (LU 1) from the 15th day, three moxa-cones per acupoint, once a day for 2 weeks. On the 16th day, 18th day and 22nd day, the incubation period of asthma was recorded. On the 29th day, all the samples were collected. The expressions of IL-17 and IL-10 in serum and bronchoalveolar lavage fluid (BALF) were detected by ELISA method. The pathological changes of lung tissue were observed by HE staining. The percentage of Th17, Treg and Th17/Treg ratio in spleen tissue were detected by flow cytometry method. RESULTS:Compared with the normal group, the incubation period of asthma in the model group was significantly shortened (P<0.01), while that in the LY group, the EA group and the moxibustion group was longer than that in the model group (P<0.01). After the intervention, bleeding and inflammatory exudation in the lung tissue were observed in the model group, and a large number of inflammatory cell infiltration around the bronchus and alveoli was found, and extensive consolidation appeared; the pathological changes of lung tissue in the LY group, the EA group and the moxibustion group were significantly reduced, and the structure of bronchus and alveoli was basically normal, and the inflammatory exudation and inflammatory cell infiltration were significantly reduced compared with the model group; the inflammatory reaction in the moxibustion group was slightly less than that in the LY group and the EA group. Compared with the normal group, the content of IL-17 in serum and BALF, the percentage of Th17 and Th17/Treg ratio in spleen tissue in the model group after intervention were increased (P<0.01), while the content of IL-10 in serum and BALF and the percentage of Treg in spleen tissue were decreased (P<0.01, P<0.05). Compared with the model group, the contents of IL-17 in serum and BALF, Th17 percentage and Th17/Treg ratio in spleen tissue in the LY group, the EA group and the moxibustion group were significantly reduced (P<0.01, P<0.05), while the content of IL-10 in serum and BALF and the percentage of Treg in spleen tissue were increased (P<0.01, P<0.05). The above indice had no significant difference among all the intervention groups (P>0.05). CONCLUSION:The Th17/Treg is imbalanced in asthmatic body. The moxibustion at lung's back-shu points and front-mu points can control asthma by regulating Th17/Treg imbalance and restoring immune homeostasis.
呃逆又称“哕逆”,古称“哕”,现俗称“打嗝”,是指胃气上逆动膈,致喉间呃呃有声,声短而频,难以自制的一种病症[1].本病相当于西医学中的膈肌痉挛,除单纯性膈肌痉挛外,尚有胃肠神经症、胃炎、胃癌、脑血管病变、肝硬化晚期、尿毒症及胸腹部手术后皆可诱发本病[2].范郁山教授为广西壮族自治区名中医,在临床工作三十余年,经验丰富,针法独特,学术造诣颇丰.余有幸跟随范师深造,得其教诲,运用针灸疗法治疗诸病,疗效显著.现将其运用针刺结合壮医药线点灸治疗的顽固性呃逆验案1则介绍如下.
"经络腧穴学"是一门桥梁课程,也是针灸推拿学专业的基础.该课程的教学质量直接影响着针灸专业其他课程的教学质量.通过长期从事该课程的教学与实践,积累了些浅显的心得体会与思考建议,试做总结.
目的:观察穴位埋线治疗子宫内膜异位症盆腔疼痛的临床疗效.方法:选取子宫内膜异位症盆腔疼痛患者32例,根据月经不同时期给予穴位埋线治疗3个月经周期,观察第一个月经周期、第三个月经周期的疗效,及停止治疗3个月后的远期疗效.结果:总有效率达84.38%.结论:穴位埋线能够有效地缓解子宫内膜异位症盆腔疼痛患者的疼痛症状,治疗用时少,刺激作用持续,值得临床进一步推广.
"针灸医籍选"是针灸推拿学专业学生的一门必修课,内容丰富,义理深奥,教师讲授和学生学习都有一定的难度.结合实际教学情况,总结中青年教师从事该门课程的教学体会,一是努力提升自身专业素质,多向经验丰富的教师学习;二是把课程思政教育融入教学中;三是教学方法尽量做到多样化.
随着国家出台《"健康中国 2030"规划纲要》《关于加强中医药健康服务科技创新的指导意见》等重要文件,确立了"健康中国"的国家发展战略,中医药的发展,尤其是针灸推拿学的发展迎来了前所未有的机遇.在健康中国建设中,针灸推拿学在中医养生、保健、医疗、康复等方面具有独特优势,是中医药"走出去"战略和推进"一带一路"建设,推动中医药海外创新发展的领头羊.
十二经筋是十二经络的重要组成部分,经筋疗法治疗在许多特定的疾病中都取得较好的效果,该文检索近10年来有关经筋疗法在临床的应用,展现经筋疗法应用于临床的主要疾病及其治疗效果,分析经筋疗法在各病种的主要治疗方法及其优势,以期能更好地将经筋疗法向临床推广.
本研究根据癫痫核心病因与阴阳跷脉循行分布、交会穴等主治特点,试图从脑肾、阴阳及睡眠几个方面论证癫痫发病与跷脉的相关性,探析从针灸跷脉论治癫痫的机制.
目的:研究针灸治疗慢性支气管炎的取穴规律.方法:从CNKI、万方、维普三大中文数据库收集1980年1月-2018年6月的针灸治疗慢性支气管炎的临床治疗论文,建立慢性支气管炎的取穴数据库,对数据进行描述统计、关联规则分析以及聚类分析.结果:针灸治疗慢性支气管炎使用频次最高的穴位依次为肺俞、定喘、肾俞;所选经络的频次最高为足太阳膀胱经;关联性最强的穴位组合为肺腧一定喘;聚类分析将所用穴位分为3类.
经筋疗法是基于《黄帝内经》的经筋理论创建的特色诊疗法,对于筋伤疾病的治疗具有优势,临床上以其在颈椎病等的运用治疗多见.通过回顾并总结近10年来运用经筋疗法治疗各型颈椎病的临床研究文献,整理得出运用经筋疗法治疗颈椎病与其他传统治方法相比较,经筋疗法疗效更佳,且其“理筋”“松肌”“解结”和“调骨”的对症治疗作用也更符合生物力学原理.反映经筋疗法在颈椎病治疗方面的现状和进程,为经筋疗法理论的不断深入挖掘与临床运用的进一步发展提供建议.