了解体外受精-胚胎移植孕妇的体力活动现状,寻找可能影响患者体力活动水平的因素.对IVF-ET孕妇孕期的体力活动水平现状进行筛选、归纳,总结影响孕妇体力活动的主要因素,提出改善措施.通过加强孕期运动知识宣教、社会及家庭支持等改善患者的体力活动现状,从而改善其妊娠结局.

目的 探讨保留不同胎数、不同减胎时机及减胎方式对多胎妊娠减胎孕妇妊娠结局的影响.方法 选取2009年1月至2019年9月该院收治的接受经阴道减胎术多胎妊娠孕妇63例作为研究对象,根据不同保留胎数分为保留双胎组(48例)和保留单胎组(15例);将减胎时机分为6～<8周和8～10周,分析保留不同胎数、不同减胎时机对妊娠结局的影响.分析采取抽吸(44例)、绞杀(5例)、注射10％Kcl(14例)3种减胎方式对妊娠结局的影响.结果 保留双胎组新生儿体重较保留单胎组低,差异有统计学意义(P<0.05);孕妇早期流产率、晚期流产率、早产率、足月率、低体重儿率与保留单胎组比较,差异均无统计学意义(P>0.05).减胎时机6～<8周和8～10周保留双胎组新生儿体重均明显低于保留单胎组,差异均有统计学意义(P<0.05);早期流产率、晚期妊娠率、早产率、足月率、低体重儿率与保留单胎组比较,差异均无统计学意义(P>0.05).抽吸、绞杀、注射10％Kcl 3种减胎方式孕妇早期流产率、晚期流产率、早产率、足月率、新生儿体重、低体重儿率比较,差异均无统计学意义(P>0.05).结论 多胎妊娠行经阴道多胎妊娠减胎术孕妇保留单胎妊娠的结局优于保留双胎者,不同减胎时机及减胎方式孕妇的妊娠结局无明显差异.

目的:研究不同体重指数对体外受精胚胎移植患者各项生育指标及妊娠结局的影响.方法:选取2014—2018年在山东省某三级甲等医院生殖医学中心就诊的407例体外受精胚胎移植患者作为研究对象,根据体重指数(BMI)不同,将其分为正常组207例:18.5kg/m2≤BMI<24kg/m2和超重肥胖组200例:BMI≥24kg/m2,分别记录其不孕年限、基础内分泌(FSH、LH、E2、PRL、P、T)、卵子总数、2PN数、优质胚胎数,并随访其妊娠结局.结果:超重肥胖组不孕年限为(2.98±1.94)年,正常组不孕年限为(3.48±2.19)年,超重肥胖组明显高于正常组,差异有统计学意义(P<0.05);超重肥胖组基础FSH为(6.69±1.80)IU/L、PRL为(354.57±202.16)mIU/L、E2为(118.54±79.92)pmol/L,正常组基础FSH为(7.24±2.56)IU/L、PRL为(354.57±202.16)mIU/L、E2为(118.54±79.92)pmol/L,超重肥胖组明显低于正常组,差异有统计学意义(P<0.05)其余指标差异无统计学意义(P>0.05);两组在临床妊娠率及活产率方面,差异无统计学意义(P>0.05).结论:不同体重指数不会对患者的卵子总数、优质胚胎数及妊娠结局造成影响,但可延长其不孕时间及影响其内分泌变化.

Objective To investigate the effects of mind mapping applied to clinical teaching on the competency of registered nurses of nursing students.Methods Using the convenience sampling method,182 internship nursing students in Grade 2012,Binzhou Medical University were selected as the object of study.They were derided into experimental and control group.The experimental group was intervened by clinical teaching model based on mind mapping,while the control group adopted the traditional clinical teaching model.A general condition questionaire and competency inventory for registered nurses (CIRN) were used to test the two groups.Results Factors such as urban and rural sources mainly affected registered nurses competency.The score of CIRN for experimental group was significantly higher than those of control group.Conclusions Clinical teaching model based on mind mapping helps to improve the registered nurses competency of nursing students.

目的 提高妇产科实习男护生的自我和谐状况.方法 将参加妇产科临床实习的122名男护生按随机数字表法分为对照组和观察组各61人.观察组采用King选标理论对妇产科实习男护生进行心理干预,对照组采用单纯以交谈为主的心理干预方法.实习结束前采用自我和谐量表测评男护生的自我和谐状况.结果 观察组男护生自我和谐总分显著低于对照组,自我与经验的不和谐性、自我刻板性得分显著低于时照组(均P＜0.05).结论 通过King达标理论对妇产科实习男护生进行心理干预,有助于促进妇产科实习男护生的自我和谐状况,使其更好地适应妇产科实习角色.

Objective To analyze the influence factors of male nursing students' self-consistency,and to investigate the effect of King's goal attainment theory on self-consistency among male nursing students during their gynecological practice.Methods By convenience sampling,122 male students of grade 2007 and 2008 of Nursing School of Binzhou Medical University were equally randomized into experimental group and control group.The experimental group were intervened with methods on the basis of King's goal attainment theory while the control group adopted the traditional teaching mode.Self-consistency and congruence scale(SCCS) was used to test the self-consistency of the two groups.Results The male nursing students' self-consistency was affected by a variety of factors,of which the only child,vocational orientation after graduation and student leader had significant impact on the disharmony between self and experience,self-flexibility and own stereotypes(P<0.05).The self-consistency levels of male nursing students in the experimental group were significantly superior to those in the control group(P<0.05).Conclusion The male nursing students' self-consistency was affected by a variety of factors.The interventions based on King's goal attainment theory may be effective in improving their self-consistency for male nursing students during their gynecological practice.

临床上部分人工流产患者手术中疼痛较重,影响手术操作及手术效果,甚至存在由于疼痛剧烈而不得不中止手术,这一点尤其在初孕妇女中尤为明显.近年来,已有多种减轻人工流产疼痛的方法应用于临床,我院于2008年1月-2009年6月对初孕6～9周要求人工流产的患者联合应用利多卡因宫颈封闭和口服散利痛,取得良好效果,现报道如下.

目前由男方因素所致的不育已占到了约40%,而导致男性不育的主要原因是少、弱精子症.在人工授精治疗中,男性少弱精是主要的适应证,但用常规上游方法处理精子所得精子密度较低,影响了临床妊娠率.本课题是研制一种专用的精液滤器,内置特制的微孔滤膜.通过该装置将精浆滤出,使精子无损伤浓集,达到或接近正常水平,再用上游法优选精子行宫腔内人工授精(IUI, 该装置尤其适用于精液量多但精子密度低的患者),临床试用结果良好,现介绍如下.

卵母细胞胞浆内单精子注射(ICSI)俗称第二代试管婴儿,是目前最先进的辅助生殖技术.方法为使用显微操作技术将精子注射到卵细胞浆内,体外培养到早期胚胎,再放回母亲子宫内发育着床.

试管婴儿技术,即体外授精-胚胎移植是治疗不孕症的重要手段.临床妊娠率从最初的6.4%[1]提高到目前的30-40%.

真菌性角膜溃疡是由真菌感染引起的一种顽固的致盲率很高的化脓性角膜炎.近年来,由于抗生素和皮质醇的广泛应用,真菌性角膜溃疡的发病率逐年增高.

复发性自然流产患者由于多次流产的发生,其承受的心理压力较大.近年来,我们对复发性自然流产患者采取积极的护理干预,取得了良好效果.现报告如下. 临床资料:选择2004年1月～2005年12月在本院生殖中心就诊的复发性自然流产患者106例,其中免疫因素68例,黄体功能不足18例,不明原因20例.

Objctive To investigate the effects of continual epidural block on intravenous vasomotory factors including nitric oxide (NO) , endothelin (ET), prostacyclin (PGI2) and thromboxane A2 (TXA2) concentrations in patients with pregnancy induced hypertension (PIH). Methods Thirty gravidas with PIH, who underwent cesarean section, served as PIH group, and ten normal late stage gravidas as normal pregnancy group (NLP group). Intravenous blood samples were taken immediately before and after epidural block to determine the concentrations of NO, ET, PGI2 and TXA2. Results Before epidural block, the concentrations of NO and PGI2 were significantly lower in PIH group than those in NLP group (P0. 01), while the concentrations of ET and TXA2 were significantly higher in PIH group than those in NLP group (P0. 01). The concentrations of NO and PGI2 were increased significantly after epidural block in both groups (P 0. 01). There were no significant statistical difference in concentrations of ET or TXA2 in both groups between before and after epidural block (P0.05). Conclusion The results indicate that decreases in NO and PGI2 concentrations and increases in ET and TXA2 concentrations may have a role in the pathogenesis of pregnancy induced hypertensioa Continual epidural block can improve the levels of vasodilative factors (NO and PGI2), while it has not obvious effect on the levels of vasoconstrictive factors (ET and TXA2).

体外受精-胚胎移植(IVF-ET)技术目前已成为治疗不孕症的重要手段.我院生殖中心从2002年11月-2004年8月共使8例患者获临床妊娠,现将8例患者的诊断和治疗过程介绍如下.

胚胎冷冻植入技术是助孕技术之一,它的优点在于一次取多个卵后,将没有使用的胚胎冷冻保存.如果病人第一次植入不成功,下次可用解冻后的胚胎进行移植,无须再进行药物注射和阴道穿刺取卵.我院生殖中心在2003年开展了该项技术,并于2004年使一名患者接受该技术治疗成功受孕,这也是鲁北地区首例接受冷冻胚胎移植成功的病例,现介绍如下.