目的:了解不同性别、年龄段结肠息肉、结肠癌的发病情况,探讨结肠息肉的分布特点.观察冷切除术、氩离子凝固术(APC)、高频电凝电切术、内镜黏膜切除术(EMR)治疗结肠息肉的疗效.方法:按年龄、性别、发病部位以及病理结果等因素,对我院接受结肠镜检查并进行病理诊断的327例患者中结肠息肉与结肠癌发病情况以及内镜下不同治疗方法进行分析.结果:327例经过病理诊断的患者中,结肠息肉检出率为58.7％,结肠癌检出率为11.9％.结肠息肉检出率随着年龄而增加,但差异无统计学意义(P>0.05);本研究性别与结肠息肉、结肠癌的发病率无关;结肠息肉以腺瘤性息肉为主,增生性息肉次之;结肠息肉以单发息肉为多,结肠在多部位有多发息肉类型.结论:男女患者40岁以上结肠息肉及结肠癌的检出率升高,因此40岁以上有肠道症状者应进行结肠镜筛查.可根据息肉单发和多发的特点,结合息肉的大小、性质,选择一种或联合两种的内镜下治疗方案,临床疗效显著,手术安全,以EMR息肉切除术最为常用.

Objective To observe the effects of volatile oil of Angelicae Sinensis Radix on blood pressure and related inflammatory cytokines of hypertensive rat models; To investigate the action mechanism of regulating the blood pressure.Methods Wistar male rats were fed withL-NNA to establish hypertensive rat models. Hypertensive rats were randomly divided into normal control group, model group, positive medicine group, volatile oil of Angelicae Sinensis Radix high- and low-dose groups, with 5 rats in each group. Each medication group was given relative medicine for gavage for 8 weeks. Non-invasive blood pressure measurement system was used to observe the systolic pressure of tail artery of rats before and after medication; the levels of ET-1, CRP, and VCAM-1 in serum were detected by the method of ELISA; RT-PCR was used to measure CRP mRNA of heart.Results The levels of systolic blood pressure, ET-1, VCAM-1, CRP and CRP mRNA in model group were significantly higher than those of normal group (P<0.05,P<0.01); Compared with model group, the levels of ET-1, VCAM-1, CRP and CRP mRNA in model group significantly decreased (P<0.05, P<0.01).Conclusion Volatile oil of Angelicae Sinensis Radix can inhibit vascular inflammatory response and then realize the effects of regulating blood pressure.

介绍刘东汉教授辨治慢性萎缩性胃炎的经验.刘教授“参西用中”,将“辨舌”作为脾胃病辨证的核心,认为本虚标实为慢性萎缩性胃炎的基本病机,治以益气升阳、健脾扶正、祛湿消痰之法,疗效卓著.

目的：观察甘草泻心汤与三黄加减治疗白塞氏综合征的临床疗效。方法：将100例白塞氏综合征患者采用随机数字表法随机分为治疗组和对照组各50例。治疗组给予甘草泻心汤与三黄加减（黄连、黄芪、黄芩）治疗；对照组给予泼尼松30 mg／次，2次／d，口服治疗。两组均以1个月为1个疗程，共治疗3个疗程。结果：治疗组治愈11例，显效11例，有效19例，无效9例，有效率为82．0％；对照组治愈4例，显效9例，有效22例，无效15例，有效率为72．0％。两组疗效对比，差别有统计学意义（P＜0．05）。结论：甘草泻心汤与三黄加减可作为临床治疗白塞氏综合征的有效治疗措施之一。

刘东汉教授提出“虚、瘀、痰、毒”是大面积脑梗死的中医证候要素,重视察舌按脉辨体,可使辨证方向明确;确立豁痰开闭、益气活血、解毒醒脑是大面积脑梗死的基本中医治法,尤为重视豁痰开闭法的运用;在用法方面,强调以猪蹄汤与水合煎药物,可促进药效发挥;并分析典型案例.

兰州大学第一医院主任医师刘东汉教授，为全国第五批老中医药专家学术经验继承工作指导老师，出身中医世家，从事中医临床工作近50年，临证思维独特，用方精纯，通晓中医内、外、妇、儿诸科，尤善在中医理论指导下救治急危重症。笔者有幸侍诊，聆听教诲，获益匪浅。兹撷取刘师救治五则案例，粗疏整理，以资借鉴。

By analyzing the course of treating the patients suffering from cerebral contusion by integrative medicine in Minxian and Zhangxian earthquake on June 22, 2013, the therapy showed the advantage of acting fast, it could give full scope to the feature and advantages of syndrome differentiation and treatment completely, as well as make up the shortcomings of only western medicine or TCM in order to provide reference for TCM therapy of critical illness.

Integrative medicine treatment on bacterial infection in 1 case shows that the misuse of antibiotics is guided selection of microbial,which lead to poor efficacy.Although there was no super bacteria concept in TCM,butits diagnosis and treatment complied with the law of typhoid fever and febrile disease.In TCM the treatment time is short,effective,in expensive and quick,simple prescription,which all reflect the uniqueness of TCM on treatment of bacterial infection.

<正>进入21世纪,癌症已经成为危害人类身体健康的第一杀手,并成为全球最大的公共卫生问题之一。据WHO报告[1],2000年全球新发癌症病人达1 010万,死亡620万。

在系统论指导下,利用多学科技术研究中西医学理论实质及其内在联系,更有利于促进中西医学找到共同语言。作者根据已发表的有关中药复方抗癫痫效应现代医学研究文献为基础,分析中药特征与抗癫痫效应的关系并建立相应的数学模型。收集、筛选1980年以来国内公开发表的2005年版《中国药典》所载中药复方抗癫痫研究的文献,根据检索结果统计不同传统功能分类、不同药性、药味、归经的中药数量和其中具有抗癫痫效应的中药味数;用多元判别分析建立回归数学模型。结果表明在这50味中药中,平肝熄风药的抗癫痫效应研究比较活跃,具有抗癫痫效应的比例为61.11%,归经分类分析,归胆经、心经、肾经的比例最多,与合计率比较,均在统计学上具有显著性差异(P<0.05)。采用逐步的Logistic回归筛选主要的影响因素,结果表明归心、脾、胆、心包经以及安神药、平肝熄风药、解表药、化痰止咳药及补虚药均是具有抗癫痫效应的重要影响因素(回归系数>0,且P<0.01)。这也与中医学有关理论相吻合。多元判别分析预测结果与原判定结果总符合率为91.6%。中药的传统功能分类、药性、归经与抗癫痫效应关系密切,以此为基础建立的数学模型可以作为中药抗癫痫效应研究及临床用药的参考。