目的 探究知柏地黄汤加减治疗2型糖尿病的效果.方法 选取2018年10月-2019年7月收治的68例2型糖尿病患者,按照随机数字表法分为试验组36例、对照组32例,试验组予以知柏地黄汤加减治疗、对照组予以西药治疗,观察不同方案治疗效果.结果 试验组治疗总有效率为94.44％,高于对照组81.25％,差异存在统计学意义(P＜0.05);治疗后,2组空腹血糖浓度、餐后2h血糖浓度、糖化血红蛋白浓度等血糖水平比较,差异具备统计学意义(P＜0.05);治疗后,2组中医症状总积分比较,差异具备统计学意义(P＜0.05).结论 对2型糖尿病患者予以知柏地黄汤加减治疗,能显著降低患者血糖水平,改善患者症状,治疗效果显著,值得临床进一步推广应用.

吴勉华教授从"瘀热"理论对放射性损伤进行辨治,认为放射性损伤病因病机多为热毒互结,瘀热相搏,气阴两伤.以清热解毒,凉血散瘀,益气养阴,润燥生津为主要治法,标本兼顾;不忘后天之本,顾护脾胃贯穿治疗始终;辨证与辨病相结合,按主症特点施治.放射治疗开始配合中药治疗,可有效防治恶性肿瘤放疗患者的放射性损伤,提高生活质量.

黄福斌教授认为久泻病位在脾,与肝肾密切相关.病机以脾虚湿盛为主,虚实夹杂为多.治疗以健脾运气,化湿利湿为基本治法,辅以温肾、疏肝、化滞、活血等.临证善用风药,升脾燥湿;补通兼施,动静结合.附验案1则以佐证.

目的 观察健脾肠宁汤加减治疗急性放射性肠炎的临床效果.方法 选取急性放射性肠炎患者147例,随机分为两组.对照组患者71例,给予氧氟沙星和蒙脱石散口服;观察组患者76例,给予健脾肠宁汤加减治疗,疗程均为14d.对两组患者治疗效果进行评价,并于治疗前后行中医症状评分.结果 观察组患者痊愈率及总有效率分别为22.37％、73.68％,均高于对照组之7.04％、30.99％ (P＜ 0.05);观察组患者治疗后中医症状腹痛、腹泻、黏液脓血便、里急后重以及乏力症状评分改善均优于对照组(P＜0.05).结论 健脾肠宁汤治疗急性放射性肠炎具有良好的临床效果,可以有效改善患者症状.

目的:观察五磨芍甘汤治疗便秘型肠易激综合征(IBS-C)肝郁气滞证的临床疗效。方法:按随机、平行对照的原则分为治疗组30例、对照组30例,治疗组口服五磨芍甘汤治疗,对照组采用聚乙二醇4000散剂(长松)口服治疗,疗程结束比较两组临床疗效。结果:两组疗效比较有显著性差异(P<0.05)。结论:五磨芍甘汤治疗便秘型肠易激综合征肝郁气滞证疗效确切,优于西药对照组。

Objective:To investigate the effects of different doses and different time of Huang Qi San Shen Yin(HQSSY) on small intestinal crypts of mouse.Methods:Total of 100 healthy Kunming mice were randomly divided into 2 groups,50 mice were treated for 2 weeks and 50 mice were treated for 4 weeks.Both 2 groups were divided into control group(n=14),low dose group(n=12),middle dose group(n=12) and high dose group(n=12).The control group was given a gavage of distilled water of the same volume with the drug,and the three experimental groups were given different doses of HQSSY,which were 1,2 and 4 times of human dosage respectively.At the end of the experiment,routine blood and small intestinal crypts of mice were measured.Results:WBC,RBC,HB and PLT in each group were not significantly different(P>0.05).Comparison of small intestinal crypts.In 50 mice after 2 weeks of treatment,there were statistical difference between the middle dose group and the control group(P<0.05);Others had no statistical significance(P>0.05).In 50 cases after 4 weeks of treatment,compared with the control group,each dose concentration group had no statistical difference(P>0.05).In the same dose concentration,there was statistical difference between the group of 2 weeks treatment and the group of 4 weeks treatment(P<0.05),while the middle dose concentration groups had very significant difference(P<0.01),which indicated that the group of 2 weeks treatment in middle dose HQSSY promote crypts cell proliferation obviously.Conclusion:HQSSY can promote the regeneration of small intestinal crypts of mice and prevent radioactive enteritis.This research can provide reliable basis for follow-up study.

1 病案摘要 患者男,42岁,因恶性胸腺瘤术后近2年,伴胸膜胸壁转移4月于2004年11月入院.患者曾于2003年3月因患胸腺瘤行胸腺切除术,术后行胸背部放疗(6MV/15MV,DT 60Gy/30f/42d).2004年8月因反复低热,伴胸背部疼痛来我院治疗.

收集近十年来中医药治疗胃癌术后的临床治疗资料,发现中医药在提高机体免疫力、降低毒副作用、增强疗效、提高生活质量、延长生存期等方面积累了丰富的经验,取得了较大的成绩。应充分挖掘中医优势,并与西医结合起来,为治疗胃癌术后提供更好的治疗方法。

笔者自1998年以来,用复方谷氨酰胺胶囊(曾用名谷参肠安胶囊)为主治疗放射性直肠炎36例,取得良好效果,现报告如下.