BACKGROUND:Studies on the association between C-reactive protein (CRP) level and poor outcomes have been yielded controversial results in patients with atrial fibrillation (AF). This meta-analysis sought to investigate the utility of elevated CRP level in predicting adverse outcomes in AF patients. METHODS:Two authors systematically searched PubMed and Embase databases (until December 10, 2022) for studies evaluating the value of elevated CRP level in predicting all-cause mortality, cardiovascular death, stroke, or major adverse cardiovascular events (MACEs) in AF patients. The predictive value of CRP was expressed by pooling adjusted hazard ratio (HR) with 95% confidence intervals (CI) for the highest versus the lowest level or per unit of log-transformed increase. RESULTS:Ten studies including 30,345 AF patients satisfied our inclusion criteria. For the highest versus the lowest CRP level, the pooled adjusted HR was 1.57 (95% CI 1.34-1.85) for all-cause mortality, 1.18 (95% CI 0.92-1.50) for cardiovascular death, and 1.57 (95% CI 1.10-2.24) for stroke, respectively. When analyzed the CRP level as continuous data, per unit of log-transformed increase was associated with a 27% higher risk of all-cause mortality (HR 1.27; 95% CI 1.23-1.32) and 16% higher risk of MACEs (HR 1.16; 95% CI 1.05-1.28). CONCLUSIONS:Elevated CRP level may be an independent predictor of all-cause mortality, stroke, and MACEs in patients with AF. CRP level at baseline can provide important prognostic information in risk classification of AF patients.

目的:观察西黄丸联合化疗治疗广泛期小细胞肺癌(S C L C)的临床效果.方法:用随机数字表法将2021年7月—2023年4月连云港市赣榆区人民医院收治的82例广泛期SCLC患者分为对照组和观察组,每组41例.对照组按照标准方案进行化疗,观察组在标准方案化疗的基础上口服西黄丸.评估两组临床疗效,并分析患者治疗前后外周血清基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶抑制剂-1(TIMP-1)、T淋巴细胞亚群(CD3+、CD4+、CD8+和CD4+/CD8+)水平,Karnofsky功能状态评分(KPS)

Objective:To treat Pelicobacter pylori (Hp) infectious gastritis (spleen damp heat syndrome) patients with Jianpi Qinghua Recipe combined with western medicine,and to analyze the therapeutic effect and Hp removal rate.Methods:Observing our hospital in recent 3years with Jianpi Qinghua Recipe combined with western medicine in the treatment of Hp infectious gastritis in 50patients as observation group,50cases treated with western medicine as controlled group,compared the two groups of patients with treatment effect and the clearance rate of Hp.Results:The observation group was significantly better than the controlled group (P＜0.05).The total effective rate of the observation group (90％) was higher than that of the controlled group (76％),and the eradication rate of Hp in the observation group was significantly higher than that in the controlled group,the difference was statistically significant (P＜0.05).Conclusion:Helicobacter pylori gastritis is treated by Jianpi Qinghua Recipe has certain effect,can effectively improve the symptoms of patients,and improve the eradication rate of Hp,safe and reliable,worthy of clinical promotion.

目的:探讨分析对老年冠心病合并高血脂症采用步长脑心通进行辅助治疗的作用及效果.方法:选取我院收治的80例老年冠心病合并高血脂症患者,随机分为对照组(n=40)和观察组(n=40);对照组进行常规治疗加辛伐他汀片治疗,观察组在常规治疗加辛伐他汀片治疗的基础上加用步长脑心通胶囊治疗;治疗后,比较两组的临床疗效.结果:进行治疗干预后,观察组的心功能改善情况明显优于对照组;观察组血脂水平的改善情况明显优于对照组;观察组的治疗总有效率(92.5％)明显高于对照组(72.5％),差异均具有统计学意义(P＜0.05).结论:在老年冠心病合并高血脂症患者的治疗中,采用步长脑心通进行辅助治疗,能够使患者的心功能及血脂水平得到明显改善,临床疗效显著,值得推广.

Objective:To investigate the efficacy of Bu Chang Nao Xin Tong capsule in the treatment of primary senile hypertension.Methods:80 patients with senile primary hypertension were selected,they were divided into the observation group and the control group according to the different drug treatment with 40 cases in each group,the control group were given the conventional antihypertensive drugs,the observation group were given Bu Chang Nao Xin Tong capsule on the basis of the control group.Results:The incidence of adverse reactions and CRP of the observation group were lower than those of the control group,and the NO,blood pressure and blood pressure were significantly higher than those of the control group.Conclusion:On the basis of conventional antihypertensive therapy,combined with Bu Chang Nao Xin Tong capsule for the treatment of primary senile hypertension,not only can control blood pressure levels,reduce CRP,increase NO effectively,but also reduce the incidence of complications during treatment,improve the quality of life of patients.

目的总结头痛的中医治疗方法 ,回顾不同辨证分型的头痛的中药、推拿、针灸疗法。方法对167例头痛患者病情辨证分析,划分不同分型,回顾性分析诊疗过程。结果 167例头痛患者可分为以下五类:气血瘀滞型61例,占36.9%;痰湿型38例,占22.6%;气血虚弱型30例,占17.9%;肝阳上亢型25例,占14.9%;肾阴虚型13例,占7.7%。不同类型患者采取不同中药药方和推拿按摩方式,疗效显著。门诊随访1年结果 :116例患者痊愈,治愈率69.6%;43例患者头痛好转,8例患者无效。结论中医治疗头痛应辨证施治,中药、推拿、针灸都是有效的治疗方法 。

小儿急性肾炎即急性肾小球肾炎,可有多种病原体引起,其中溶血性链球菌感染引起最为常见,是临床儿科的常见病、多发病,以血尿、蛋白尿、水肿、高血压等为主要表现。本病未及时治疗,部分患者会在短期内发展至急性循环充血、高血压脑病、急性肾功能衰竭等。本病属中医学中的"水肿"范围,其发生的根本原因是肺、脾、肾三脏功能失调,感受风邪、水湿或疮毒入侵诱发。临床治疗时需要根据临床症状,辨清病因、病位,辨证论治。

急性肾衰竭发生是由多种原因引起的临床综合征,在数小时至数天内肾功能急剧下降,内环境发生严重紊乱,如果早期诊断和干预治疗可以逆转病情。对急性肾衰竭正确及时的早期诊断和鉴别诊断对其预后有着极为重要的影响。中医在急性肾衰竭的治疗方面取得较为满意的效果。