I1 World Congress for Integrative Medicine & Health 2017 - A global forum for exploring the future of comprehensive patient care Benno Brinkhaus1, Torkel Falkenberg2,3, Aviad Haramati4,5, and Stefan N. Willich1 1Institute for Social Medicine, Epidemiology and Health Economics, Charite – Universitatsmedizin Berlin, Berlin, Germany; 2Department of Neurobiology Care Sciences and Society, Division of Nursing, Research Group Integrative Care, Karolinska Institutet, Stockholm, Sweden; 3I C – The Integrative Care Science Center, Jarna, Sweden; 4Department of Biochemistry, Molecular and Cellular Biology, Georgetown University, Medical Center, Washington, DC, USA; 5Department of Medicine, Georgetown University Medical Center, Washington, DC, USA We are excited to present the abstracts of the keynote speakers, parallel sessions and oral and poster presentations of the World Congress on Integrative Medicine & Health (WCIMH 2017; http://www.ecim-iccmr.org/2017/) to be held in Berlin on May 3-5, 2017, which will be jointly convened by the European Society of Integrative Medicine (ESIM) and the International Society for Complementary Medicine Research (ISCMR). The Congress will take place in association with a number of national and international organizations from North America and other continents. Consequently, the congress will provide the most comprehensive global forum and perspective in the field of Complementary and Integrative Medicine in 2017. The congress goal is reflected in its tag line: The Future of Comprehensive Patient Care - Strengthening the Alliance of Researchers, Educators and Providers. We believe that by bringing together researchers, educators and providers, who are addressing various aspects of Integrative Medicine and health, we can build on the evidence obtained through research to inform clinical education and practice and thereby create a better platform for comprehensive patient care. The main themes of the Congress are: Clinical care: The practice of Integrative Medicine should be based on distinct definitions, should be informed by evidence and evolve from guidelines that are developed by experts from conventional and complementary medicine. Education: Academic leaders and health officials have called for future clinicians to possess the knowledge and skills to understand how Integrative Medicine can be incorporated into conventional care to improve the health of the public. Therefore, it is essential to share best practices in how to create robust curricular opportunities for medical students to experience systematic teaching of the principles, strengths and limitations of Integrative Medicine. Research: Within this Congress scientists will showcase the highest quality research worldwide in this field and will provide the state-of-the-science evidence base through plenary lectures, symposia and abstract presentations. Traditional healing systems (THS): Traditional healing practices and practitioners are an important and often underestimated part of health care. THS is found in almost every country in the world and the demand for its services is increasing. Research contributing to evidence informed decision making is imperative to develop a cohesive and integrative approach to health care that allows governments, health care practitioners and, most importantly, those who use health care services, to access THS in a safe, respectful, cost-efficient and effective manner. Arts and medicine: For the first time at a research congress, this theme will explore the important contributions of the arts (music, visual arts, dancing, etc,) for integrative therapeutic interventions to achieve optimal health and healing. Given the ambitious scope of this worldwide international congress, the four authors of the present editorial serve as co-presidents and they are guided by the International Organizing Committee consisting of many experts from around the world including Myeong S. Lee, Jianping Liu, Kenji Watanabe (from Far East Asia), Renee Street (Africa), Amie. Steel (Australia), Paulo Arturo Caceres Guido, Chin An Lin (South America), Heather Boon, Josephine Briggs, John Weeks (North America) and Abdullah Al-Bedah, Mohamed Khalil, Elad Schiff (Middle East and Israel). The programming for each of the five themes is directed by WCIMH 2017 theme subcommittees involving some of the most highly regarded clinicians, educators and researchers in the world in this field (in alphabetic order): Linda Balneaves, Lesley Braun, Eva Bojner Horwitz, Gustav Dobos, Jeffery Dusik, David Eisenberg, Iva Fattorini, Eckhart G. Hahn, Suzanne B. Hanser, Frederick Hecht, George Lewith, Harald Matthes, Andreas Michalsen, Judy Rollins, Volker Scheid, Michael Teut, Robert Saper, Claudia M. Witt, Merlin Wilcox and Darong Wu. The Local Organizing Board is coordinated by M. Cree. We are very grateful to all organisations and individuals working diligently to making this first World Congress for Integrative Medicine & Health in 2017 a great success. We are also pleased to announce that the opening welcome will include the Director General for the World Health Organization, Dr Margaret Chan (on video). All plenary speakers are internationally recognized experts in the field of Complementary and Integrative Medicine such as Josephine B Briggs (US) and Merlin Willcox (UK) as keynote speakers for the theme traditional healing systems; Klaus Linde (Ger) and Michael Moore (UK) for the research theme; Lisa M Wong (US) and Tores Theorell (Sweden) will address the theme of arts and medicine; Darong Wu (China) and Jeffery A Dusek (US) are presenting on the theme of clinical care; and Aviad Haramati and David Eisenberg (both US) will close the Congress with presentations on education. In addition, more than 100 oral presentations in over 40 parallel sessions will be in the program to provide newly emerging data from recent research projects, experiences from new treatment aspects in clinical care, descriptions of new models of education in medicine, information about integration of traditional healing systems in health care systems and new aspects on the integration of arts in medicine. In addition, more than 400 posters will be presented in guided poster sessions during the three days of the Congress. To translate the congress goals and objectives into a tangible action for the field, a Berlin Agreement is being developed. With the title ‘Social and Self-responsibility in practicing and fostering Integrate Health and Medicine Globally,’ this document is meant to help shape the future of comprehensive patient care in Integrative Medicine, and addresses the responsibilities of all participants, including patients and citizens, physicians and all colleagues working in the healthcare system. The Berlin Agreement has been developed by the WCIMH 2017 congress presidents and the International Organizing Committee to create a document for further distribution to the scientific and clinical community and to health care stakeholders, decision makers, and politicians. We anticipate having the final version of the Berlin Agreement endorsed by a number of organizations prior to the Congress and also soliciting the support of congress at the WCIMH 2017 in Berlin. Our hope is that this document will provide an important impetus for further engagement world-wide after the Congress has concluded. Immediately before the start of WCIMH 2017 on Wednesday May 3rd 2017 there will be several high-quality pre-conference workshops covering all congress topics. Reflecting the political situation in recent years, especially in Europe, we have arranged for a unique half-day workshop on the topic: “Refugees with Chronic Diseases between the Middle-East and Europe: The Role of Traditional and Integrative Medicine in Bridging Gaps”, The speakers are all from the Middle East and Europe and will address how Integrative Medicine may serve as an important element to overcome the problematic health situation of refugees around the world. We are convinced that the field of Complementary and Integrative Medicine, including traditional healing systems and medicine and the arts, will benefit from The 2017 World Congress on Integrative Medicine & Health—a preeminent scientific international forum that is focused on highlighting advances in these thematic areas. We invite all practitioners, educators and researchers in the field of Integrative Medicine to come together, participate and engage together to make this Congress an exciting meeting for the successful advancement of Integrative Medicine across the globe.

Objective: To explore the relationship between gastrointestinal heat retention syndrome and the incidence of pneumonia and recurrent respiratory tract infections (RRTIs) in children. Methods: A prospective cohort study was conducted in the pediatric outpatient department of Beijing Dongfang Hospital. Children without respiratory tract infections (RTIs) were consecutively recruited according to the selection criteria. A semi-structured questionnaire was used to record traditional Chinese medicine (TCM) symptoms and demographic and physiological characteristics. Gastrointestinal heat retention syndrome was considered to be a predisposing factor and was diagnosed according to a scale with reliability and validity. The participants were followed up for 12 months. Participants and their parents or guardians were contacted via clinical interviews and telephone every 6 months. Episodes of pneumonia and RTIs were recorded in detail. Results: A total of 420 children were included. Of participants, 370 (88.10%) were followed up for 12 months. The mean number of RTI episodes per participant was 5.37 (95% CI: 5.14 to 5.60). In total, 186 participants in the gastrointestinal heat retention syndrome group and 184 participants in the non-gastrointestinal heat retention syndrome group completed the 12-month follow-up period. The baseline of both groups was comparable. The incidence of RRTIs in children with gastrointestinal heat retention syndrome was 1.27 (95% CI: 1.01 to 1.59) times that in children without gastrointestinal heat retention syndrome. Logistic regression analysis revealed that abnormally increased appetite with frequent hunger, foul breath, dry stools, and dark red or purple fingerprints were positively correlated with the incidence of pneumonia. Irascibility and feverish feelings in the palms and soles were positively correlated with the occurrence of RRTI. Conclusions: Gastrointestinal heat retention syndrome is a risk factor for RRTIs in children. Studies with larger sample sizes and longer follow-up time are warranted to confirm the degree of causal risk associated with RTIs.

Purpose: Unexplained chronic fatigue (CF) is common symptom in worldwide. According to the theory of Korean Medicine (KM), CF is considered to be the imbalance of interorgan functions or the four essential components of the human body, including qi, blood, yin and yang. Thus CF appears to have individual differences, it can be subdivided into different pattern identification (PI) for a personalized diagnosis in KM. However, there are no diagnostic tools, such as questionnaires or medical devices. The purpose of this studywas to develop PI questionnaires and to complete a clinical trial to determine the correlation between CF and Qi Blood Yin Yang Deficiency Questionnaires (QBYYDQs). Methods: A total of 151 participants, including 121 CF patients and 30 healthy subjects, were asked to complete the QBYYQs. Two Korean medical doctors independently assessed participants’ qi, blood, yin and yang deficiency patterns (DPs) by the PI guidelines. We selected reliable questionnaire items for symptoms corresponding to each DP based on the results of a preliminary study. These itemswere used to estimate internal consistency and construct validity. A multinomial logistic regression analysis (MLRA) was performed by each DP score. Results: The qi (9 items), blood (8 items), yin (9 items) and yang (6 items) DQs showed sufficient internal consistency (0.816, 0.826, 0.807 and 0.717, respectively). Two subscales from each DQ were extracted by an explanatory factor analysis. The variances for each qi, blood, yin, and yang DQ were 52.8%, 58.0%, 52.2%, and 63.5%, respectively. Odds ratios from the MLRA demonstrated that each deficiency score was positively associated with each corresponding DP (adjusted odds ratio: qi score=0.041, blood score=5.877, yin score=12.57, yang score=13.56, reference category: qi deficiency). Conclusion:These results suggest that the QBYY-Q is a reliable and valid instrument for estimating the influence of qi, blood, yin and yang deficiencies on CF. Contact: Jihye Kim, wisdom00311@kiom.re.kr

Objective: To explore the association between dietary habits and recurrent respiratory infection (RRI) in children aged 0–14 years. Methods: This case–control study compared dietary data of children with (cases) and without RRI (controls) collected via structured questionnaire. Participants were recruited from Chinese medicine clinics, hospitals, and children's learning institutions in Beijing. A logistic regression analysis and odds ratio (OR) calculations were conducted using SPSS 17.0 software. Results: A total of 241 questionnaires were collected (case:control ratio: approximately 2:1). Frequent consumption of processed foods (OR = 2.988, 95% confidence intervals 1.375–6.491) and high-sugar foods (OR = 2.268, 95% confidence intervals 1.163–4.424), frequent picky eating (OR = 2.614, 95% confidence intervals 1.363–5.014), and a meat-heavy diet with fewer vegetables (OR = 1.830, 95% confidence intervals 1.358–2.467) correlated positively correlated with RRI. Additionally, 57.80% of the children with RRI were addicted to high-sugar foods, compared with 41.57% of the children without RRI (P = .015). Furthermore, 63.16% of the children with RRI were picky eaters, compared with 48.31% of the children without RRI (P = .024). Finally, 30.92% of the children with RRI frequently consumed processed foods, compared with only 17.98% of the children without RRI (P = .027). Conclusion: Although RRI correlates positively with several dietary habits, in the future, prospective cohort studies with larger samples are needed to generalize these findings.

《伤寒论》中麻黄与石膏配伍常用于外寒兼见内热。仲景表里双解之时,多以石膏伍麻黄,而非芩连等苦寒药物。仲景应用麻黄石膏之品,解表时麻黄用量在麻黄汤中3两麻黄的基础上常见增加,而清里时石膏用量在白虎汤中1斤石膏的基础上常见减轻,如麻杏甘石汤等。简言之,《伤寒论》麻黄石膏表里同治之要为:表里双解,多以石膏伍麻黄;石膏为伍,解表麻黄量酌增;表邪未尽,清里石膏要减轻;剂量比例,仍待临证所决定。

曹颖甫为近代经方大师,其门人所辑的《经方实验录》是其医案编,是知名经方医案著作.其书第九案,麻黄汤证其三(曹颖甫师讲授,姜佐景笔记)记述如下:若华之母,于六月二十三日亲至小西门外观看房屋,造回家,已入暮,急欲睡,遂盖被卧,恶寒甚,覆以温衾,亦不能温,口角生疮,而目红,又似热证,腹中和,脉息浮紧有力,天时炎暑,温覆已久,汗仍不出,身仍无热.处方:麻黄二钱,桂枝二钱,杏仁三钱,甘草一钱.服后,温覆一时,不动声色.再做一剂,麻桂均改为三钱,仍不效.更予一剂,如是续作续投,计天明至中午,连进四剂,了无影响.计无所出,乃请章次公来商,曰;当予麻桂各五钱,甘杏如前.

[Objective] To define the signs and clinical application range of Shuanghuanglian formula.[Method] Combine with TCM theory,discuss the function and clinical application range of Shuanghuanglian from herbs,febrile disease and 6 channels.[Result] Its main components are honeysuckle,scutellaria and fructus,mainly used in clearing heat and toxin,without clearing wind and superficial.Viewing it can clear wind and superficial is because of misreading Yinqiao Powder;Shuanghuanglian shall point to signs of excessive heat inside,not fit for superficial signs of cold in the beginning.[Conclusion] Shuanghuanglian only clears internal heat,not fit for early cold in clinic;it is proper to clear wind and superficial.

Urticaria is a common clinical skin disorders.Classical prescription is the classic disciplines of the traditional Chinese medicine,which uses the six meridian syndrome differentiation.Body itch is the common clinical symptoms found in Urticaria.By analyzing literatures and using clinical experience,it is found body itch belongs to the exterior syndrome in most cases,thus treatment should be made from the exterior,but sometimes urticaria can be found in each meridians,such as belongs to the interior syndromes or the half exterior and half interior syndrome.So the key point of use the classical prescription to treat urticaria is using the six meridian syndrome differentiation firstly,and using prescriptions and syndromes differentiation secondly.Because the prescriptions and the syndrome are corresponding,so it can achieve good results of urticaria treatment.So urticaria treatment by the classical prescription,the key point is using the six meridian syndrome differentiation firstly,then using prescriptions and syndromes differentiation.

目的:通过了解青海大通地区中医药应用情况,进而掌握该地区的中医药应用情况,加以分析后,以期对西部高原多民族聚集地区的中医药应用及发展有一定的指导作用。方法:根据现有文献资料,结合当地实际情况设计调查问卷,对青海大通地区居民进行问卷调查,并对收集来的问卷进行统计,参考相关文献进行分析。结果:目标人群中医药服务需要迫切,但需求未得到充分满足。结论:针对以青海大通县为代表的西部高原多民族聚集地区居民中医药服务需要旺盛的情况,可以考虑加强对当地居民中医药知识的科普宣传及教育,积极提升卫生诊疗水平,推广中西医结合卫生服务等,以满足基层群众日益旺盛的高质量的医疗服务的迫切需求。

As to the diagnosis and treatment of tinnitus,syndrome differentiation is not out of six-meridian syndrome differentiation.Clinically,the doctor should follow the principle of differentiating the six meridians the first and differentiating the formula and syndrome the second,identify in detail the assignment of six meridians,differentiate the cold and heat,interior and exterior,deficiency and excess.Only in this way can the doctor not make a mistake of principle.Tinnitus is manifested as pathogenic qi disturbing the orifices,which mainly belongs to Shaoyang semi-exterior and semi-interior heat syndrome,but the symptoms of Taiyin water stagnation attacking upward are not uncommon.For the tinnitus caused by Shaoyang heat of semi-exterior and semi-interior syndrome,Shaoyang reconciliation method may obtain an effect;for the tinnitus caused by Taiyin interior,deficiency,cold,and the upward attack of water retention,the method of warming the stomach,dropping the adverse and soothing the water retention may be effective.

大青龙汤即麻黄汤与越婢汤的合方,也可以认为是麻黄汤加人生姜、大枣和生石膏而成. 因大青龙汤条文记载"若脉微弱,汗出恶风者,不可服之.服之则厥逆,筋惕肉(瞤),此为逆也",故该方一直被誉为发汗重剂,如成无己曰:"大青龙汤,发汗之重剂也,非桂枝汤之所同,用之稍过,则又有亡阳之失."[1]正是因为大青龙汤被誉为发汗重剂,致使其临床的应用受到了限制.本文对大青龙汤方证进行探讨,旨在明确其临床应用指征.

Shengshigao is commonly used to clear Yangming heat.It is can be found from Shanghanlun and Jinkui Yaolue,thirsty which is Baihu Jia Renshen Decoction pattern and not Baihu Decoction pattern.So it can be seen that the treatment of thirst is Renshen and not Shengshigao,because Renshen can tonify the stomach and generate fluid.It is wrong that Shengshigao is generally considered to treat the thirst.Shengshigao is commonly used to clear the Yangming heat by ZHANG Zhongjing,but not Huangqin or Huanglian,which can expell the heat evils both in the superficies and in the interior,for the reason that Shengshigao can clear and let out the heat.Because Shengshigao can clear the heat and not affect the function of expelling superficial evils,whenever we see a dry-mouth,irritability and other symptoms of the Yangming heat,Shengshigao can be used,for example,Xiaoqinglong Jia Shigao Decoction and etc.

Objective:To investigate the distribution of constitution in highland people of Qinghai province and the effect of different ages,marriage and genders,which could provide evidence for the prevention and treatment.Methods:The current situation of more than 300 people's constitution in Qinghai province was studied with the standard constitution scale.Results:42 people were mildly constitution,19 were partial constitution while 194 clamp partial constitution.In 8 partial constitutions,the most was qi deficiency(98 cases,41.53%),following by yang deficiency(77 cases,32.63%),yin deficiency(68 cases,28.81%),phlegm-damp(65 cases,27.54%),qi stagnation(66 cases,27.97%),damp-heat(56 cases,23.73%),mildly constitution(42 cases,17.80%),blood stasis(40 cases,16.95%),allergic constitution(33 cases,13.98%).There were differences among gender,marriage and ages.Conclusion:There are differences of constitution distribution in highland people in Qinghai province,the clamp partial constitution makes certain proportion.Qi deficiency,yang deficiency,yin deficiency,phlegm-damp,qi stagnation are the top five.The altitude environment,gender,marriage,age and dietary habit could affect the constitution.Treatment in accordance with seasonal conditions,local conditions and the patients' individuality could balance the constitution and improve the quality of life.

Classical formulas attach great importance to syndrome differentiation of deficiency and excess,emphasize the selection of an appropriate treatment regimen according to the level of struggle between the healthy qi and pathogens,either eliminating pathogens to reinforce the healthy qi,or reinforcing the healthy qi to eliminate pathogens.On the basis of syndrome differentiation of six meridians,the paper emphasizes the reinforcement of the healthy qi and the treatment with both elimination and reinforcement to eliminate pathogens but not to hurt the healthy qi.It is concluded that yang qi,blood and body fluids should be paid attention to in the clinical process,and blind attack to the pathogens be prohibited.

Objective Bodily itch is a common clinical symptom that often found in skin diseases such as urticaria and psoriasis.It is one of the most common associated symptoms of dermatology disorders.By analyzing literatures and using clinical experience,it is found bodily itch belongs to the exterior syndrome in most cases,thus treatment should be made from the exterior.Methods Shanghanlun had much discussion on bodily itch,after analyzing and interpreting we found that it was commonly consider as exterior syndrome and it should be treated from the exterior.Doctors at the later periods shared similar views,and often got satisfactory clinical result.Results Bodily itch was belong to the exterior syndrome judging from clinical practice,thus using the exterior principle for treatment,satisfactory clinical result has been obtained.Conclusion Bodily itch can be found in each meridian of the six meridians,however most of the time it is found in the exterior syndrome.According to Shanghanlun it should be treated from the exterior.Therefore satisfactory clinical result can be obtained with treating exterior for bodily itch that is diagnosed as exterior syndrome.

Banxiahoupu Decoction come from Jin Gui Yao Lue,and it is generally considered specialy to cure the globus hysteriocus,which severely restricted its clinical application.The subject range of prescription should be based on the syndrome.Banxiahoupu Decoction is based on the Xiaobanxia and Fuling Decoction,added the Sue leaves to run the Qi,and add the Houpo to lower adverse qi and removephlegm,so Banxiahoupu Decoction could be made to cure the cough caused by fluid retention.This paper not only explained the theory of the fluid retention induced cough from the literatures as Shang Han Lun,Jin Gui Yao Lue,Wen Bing Tiao Bian,but also analyzed evidence from the medical records which proved the Banxiahoupu Decoction can cure the cough caused by fluid retention.

<黄帝内经>、<伤寒杂病论>被称作中医学经典,分别成书于秦汉时期和东汉末年,虽然2部著作成书年代相去不远,但理论指导思想却大相径庭.历代认为<伤寒论>理论来源于<黄帝内经>,其依据就是<伤寒论>序中有"撰用素问、九卷、八十一难、阴阳大论、胎胪药录并平脉辨证"23个字.因此,历代医家多以<内经>解读伤寒,致使仲景学术本源累世迷惑莫辨.

甘草泻心汤出于<伤寒论>,其辛开苦降、寒热并用、健脾清热化痰、标本兼治,临床对于脾虚痰热所致的慢性复发性口腔溃疡有独特疗效.

八纲是中医重要理论,八纲辨证是临床最基础和适用范围最广的辨证方法。但近来医家多认为八纲确立于近代,八纲一名虽然始自近代祝味菊先生,但历代已对八纲进行了论述,并已明确指出八纲的临床重要性和实用性。从中医理论源泉的《黄帝内经》中可见大量的对八纲实质内容的论述,八纲实际上起源于《黄帝内经》。