The article provides information on the efficiency of thermal injury healing in animals (rabbits) under light therapy with «Bioptron», «Ricta», «Azor», 0KN-11M, BOP-4. An analysis has been done of the results of the morphological and planimetric research within 5-15 days after wounding. The factual data received have led to the conclusion that it is advisable to combine different physiotherapeutic practices in wound treatment. Synchronization of processes of an epitelization and maturing of granulyatsionny fabric allowed to recommend for appointment different lengths of waves of optical range in a certain sequence, beginning from ultra-violet beams of short, average range, then laser radiation of an infrared, red range, and also their combination, then to continue influence by the polarized light through standard periods (courses).
The article presents the results of experimental biological modelling of single and subacute introduction of Ciprofloxacin to the rabbits. State of an organism of animals was estimated by biochemical, hematological, hemostatic and morphologic indices. Introduction of preparation samples was intravenous, according to the Instruction of medical use. Main result of the experiments is determination of toxic effects that are typical for fluorinequinolone and developed on the background of multiple introduction of preparation in the doses higher than therapeutic.
An. experimental research, of infusion solution of Metronidazole at single and repeated administration to the animals (rabbits) was carried out. Distinct signs of toxicity of the researched pattern. in the dose that is ten times higher than maximum, daily dose were determined. It concerns statistically reliably changed hematologic, biochemical and. electrophysiological indices that are typical for Metronidazole in particular. Only the fact of increase of content of creatinine in blood serum in 2 weeks after the administration, of the preparation should be registered but in this case it can be the signal to stop further administration, of the preparation.
We carried out an experimental research of infusion solution of potassium, and magnesium asparaginate at the single and. repeated introduction to the animals (rabbits). We determined the fact of the demonstration of toxic features of the preparation at single introduction in shock doze (243,5 mg/kg): increase of hepatic enzymes activity and. of some other biochemical indices, decrease of cardiac beat rhythm and. appearance of plural extrasystoles.