Results of the continuous monitoring of the Naroch lake system, which includes eutrophic Lake Batorino, mesotrophic Lake Myastro, and oligomesotrophic Lake Naroch, have been used to study the factors that largely affect the long-term dynamics of the lakes ecosystem under variable nutrient loading. A set of continuous series of average seasonal values of eight parameters from each ecosystem over 1978–2015 is analyzed using the SSA and PCA methods. The second principal component (F2), which contributes 15.3, 20.5, and 22.1% to the dynamics of the ecosystems of lakes Myastro, Batorino, and Naroch, respectively, is associated with three parameters that reflect the processes of formation and decomposition of the organic matter. A comparison of the periods of the dominant cyclical components of principal component F2 and related ecosystem parameters allows us to interpret the second main factor behind these components as activity from solar radiation.

Abstract Introduction Prehypertension is a medical classification for patients with above normal blood pressure (BP) but insufficient for confirming hypertension diagnosis. Condition is often asymptomatic as it gradually develops over the years, yet recent meta-analyses suggest that prehypertension is a significant risk factor for stroke and other cardiovascular diseases. Methods We analyzed phenotypic data from 879 (age 25–64) individuals without hypertension from a population based-sampling cohort of St. Petersburg region in the North-West of Russia to identify clinical risk factors associated with prehypertension condition. All patients were divided in two groups – optimal BP (systolic BP <120 mmHg and diastolic BP <80; N=426) and prehypertension (systolic BP in range 120–140 mmHg and diastolic BP in range 80–90 and not on antihypertensive therapy; N=453). Results Phenotypic analysis with linear regression was corrected for age, sex, smoking status, BMI and levels of LDL and HDL cholesterol (Figure 1). Interestingly, blood level of insulin was significantly associated with prehypertension status along with insulin resistance index, however, presence of diabetes diagnosis in medical history was not significant. Phenotypes associated with prehypertension suggest that prehypertension is often developing along with hyperinsulinemia. Finally, we estimated polygenic risk scores (PRS) for hypertension using UK biobank GWAS summary statistics and confirmed that prehypertension is more frequent at earlier age in patients with higher genetic susceptibility (Figure 1, Figure 2). Conclusions Hyperinsulinemia and genetic susceptibility to hypertension are strong risk factors for prehypertension. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): This work was financially supported by the Ministry of Science and Higher Education of the Russian Federation (Agreement No. 075-15-2020-901) to Al.K. Figure 1. Clinical markers of prehypertensionFigure 2. Genetic markers of prehypertension

Aim. To assess the association of cardiovascular risk factors with various vascular aging phenotypes using the St. Petersburg population sample as part of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. The current analysis, performed within the ESSE-RF multicenter observational study, included 1600 St. Petersburg residents. The participants filled out a questionnaire to assess risk factors. In addition, blood biochemical parameters, anthropometric characteristics, and blood pressure were evaluated. Pulse wave velocity (PWV) was assessed by applanation tonometry using the SphygmoCor device (AtCor, Australia) in 524 people. For analysis, 485 participants without prior cardiovascular events were selected. PWV ≤10 percentile of PWV for healthy individuals in each age group was considered as the criterion for supernormal vascular aging (SUPERNOVA) phenotype, the PWV ≥90 percentile — early vascular aging (EVA), the PWV of 10-90 percentile — normal vascular aging (NVA).Results. The prevalence of SUPERNOVA phenotype was 9,7%, EVA — 18,8%, NVA — 71,5%. Patients with EVA phenotype were more likely to have HTN (60,4%) in comparison with those with SUPERNOVA phenotype (17%) and, less likely — high physical activity (39,6 vs 53,2%). Obesity, hyperglycemia, insulin resistance, hypercholesterolemia, dyslipoproteinemia, and excessive alcohol consumption were significantly less common in participants with SUPERNOVA phenotype compared with those with EVA phenotype.Conclusion. In addition to HTN and dyslipoproteinemia, a significant predictor of premature aging was the cumulative effect of obesity, insulin resistance and hypertriglyceridemia. Among behavioral risk factors, higher physical activity and adequate alcohol consumption were factors associated with supernormal aging.

Дифференцированный подход к проведению профилактических и противоэпидемических мероприятий среди военнослужащих на основе шкалы оценки

The International Society of Hypertension and the World Hypertension League initiated a blood pressure screening study called May Measurement Month 2019 (MMM19) to improve the detection of elevated blood pressure (BP) and to assess BP control in patients with hypertension (HTN).Aim. To assess adherence to treatment of the hypertensive population according to MMM19 campaign in Russia.Material and methods. During May 2019, 5394 people from 21 regions of Russia took part in the screening. Participation was voluntary and did not imply gender restrictions; all subjects were over 18 years of age. During the screening, BP was measured three times using electronic and mechanical sphygmomanometers, as well as a questionnaire on the diabetes, history of cardiovascular events, smoking, and alcohol consumption was filled. Information was also collected on the date of last BP check and the administration of statins, acetylsalicylic acid and antihypertensive drugs. Data on height and body weight was obtained from respondents.Results. The analysis included data from 5274 participants aged 18 to 96 years (men — 1834 (34,8%)). Median age was 25 years, quartiles — 20 and 49 years. According to MMM19 data, the proportion of HTN patients in the Russian population was 31,9%, and with the exception of participants under 25 years old — 51,5%. Patients with HTN over 25 years old take antihypertensive therapy in 73,6%; 38,6% are characterized by irregular drug intake. Only 11,8% of men and 17,2% of women reach the target blood pressure <130/80 mm Hg. Only 20-30% of patients who used 4-5 antihypertensives reached the target BP level.Conclusion. According to MMM19 in Russia, only a third of high-risk patients measured BP over the past 12 months. There is also low adherence to antihypertensive therapy and inadequate control of HTN. Patients with HTN and a history of cardiovascular events are more likely to take antihypertensives regularly.

Background. Arterial stiffness, which is a marker of vascular damage and cardiovascular disease independent predictor, can be used as an indicator of vascular aging. Vascular changes may occur in some individuals earlier than it comes according to chronological age (early vascular aging syndrome) or later (healthy aging). SUPERNOVA (supernormal vascular aging) is a new protective phenotype in which very low arterial stiffness values are recorded regardless of the level of risk factors exposure.Objective. To assess the prevalence of SUPERNOVA phenomenon and risk factors in St Petersburg population-based sample.Design and methods. The survey of 1600 St Petersburg residents aged 24-65 years was performed in terms of the epidemiological observation study ESSE-RF (2012-2013). Anthropometry and fasting blood sampling for lipids and glucose detection and blood pressure measurement according to standard methods were performed. Pulse wave velocity (PWV) assessed by SphygmoCor (Australia) was performed in 524 people. 485 participants were selected without cardiovascular complications history. The participants were divided by age into 5 groups: persons under 30 years, 30-39 years, 40-49 years, 50-59 years, 60 years and older. PWV < 10th percentiles for healthy individuals PWV (Reference Values for Arterial Stability’s Collaboration, 2010) was detected as SUPERNOVA phenomenon in each age group. Mathematical and statistical data analysis was implemented using IBM SPSS Statistics 20.0.Results. SUPERNOVA phenomenon prevalence was 9,8 % (48 participants): 11,9 % women (32 participants) and 7,4 % men (16 participants). Among women systolic blood pressure (SBP) levels (p = 0,01) and body mass index (BMI) (p = 0,055) were significantly lower. Subjects with SUPERNOVA showed significantly lower SBP and diastolic blood pressure (DBP), BMI, glucose, triglycerides and lower prevalence of arterial hypertension (HTN), obesity, hypercholesterolemia and hypertriglyceridemia. In participants younger 30 years only obesity prevalence was significantly lower in respondents with SUPERNOVA, based on BMI criterion (p = 0,046). Participants aged 30-39 years showed no significant differences. In the group aged 40-49 years BMI (p = 0,02), abdominal obesity prevalence (p = 0,05), as well as SBP levels (p = 0,03) and DBP (p = 0,05) was significantly lower in individuals with SUPERNOVA. In the group aged 50-59 with SUPERNOVA significantly lower HTN prevalence (p = 0,03), glucose levels (p = 0,005) and BMI (p = 0,04) were found. In the older age group of 60-65 years subjects with SUPERNOVA have significantly lower levels of SBP (p = 0,014) and DBP (p = 0,014), as well as significantly lower prevalence of HTN (p = 0,03).Conclusions. At population level the phenomenon of supernormal vascular aging occurs in about 10 % without significant gender prevalence. HTN, obesity and metabolic factors are the determining factors of vascular aging. Ideal vascular health is associated with age-specific features.

The aim of the study was the self-assessment by medical students of the level of IT competence and the identification of factors that influence this level. A survey of 52 2nd year students of the Faculty of Medicine was carried out. 42% of students plan to combine work as a medical practitioner and research. Self-assessment of competence in the field of information technology showed a good command of the search engines Google and Yandex, individual Microsoft Office applications, insufficient knowledge of Exell and Access. Selfassessment of competence is higher among students who plan to engage in research work.

Purpose. Assessment of prevalence of arterial hypertension (AH), need for prescription of antihypertensive therapy (AHT), and efficacy of AHT in Russian population in accordance with novel guideline of the American College of Cardiology/American Heart Association ("American recommendations") on diagnosis and treatment of AH (2017). Materials and methods. Epidemiological study ESSE-RF ((sic)CCE-P Phi) was carried out in 12 regions of Russian Federation (RF) with different climatic-geographic characteristics. Number of examined residents of RF aged 25-65 years was 20 652. The sample was stratified by gender and age. Examination included anthropometry, laboratory tests, blood pressure (BP) measurement with the OMRON tonometer. The SCORE scale was used for evaluation of risk of development of cardiovascular diseases (CVD). In American recommendations AH was defined as follows: 1-st degree - systolic BP (SBP) 130-139 and/or diastolic BP (DBP) 80-89 mm Hg, 2-nd degree - BP >= 140/90 mm Hg and/or presence of AHT. In recommendations of the European Society of Cardiology (2013, 2018) ("European recommendations") AH was defined as BP >= 140/ 90 mm Hg and/or presence of AHT. Results. We analyzed data of examination of 20 607 participants - 7806 men (37.9%) and 12 801 women (62.1%). According to European recommendations AH was diagnosed in 10 347 persons (50.2%) - 3987 men (51.1%) men and 6 360 women (49.7%). According to American recommendations AH was registered in 14 853 persons (72.1%) 6 059 men (77.6%) and 8 794 women (68.7%). AHT received 6324 persons (61.1% of those with AH); according to American recommendations, the onset of AHT was indicated to additional 620 persons with 1-st degree AH because of high CVD risk. Among all participants with AH (on and without AHT) strengthening of AHT for achievement of target BP level was required in 77.8 and 92.6% of patients according to European and American recommendations, respectively. Conclusion. Application of novel criteria of AH diagnosis from 2017 ACC /AHA guideline to Russian population would increase prevalence of AH up to 72.1%. Onset of AHT would be indicated in 13.8% of patients with 1-st degree AH, while in 93% of patients receiving AHT its strengthening would be required.

Aim . To assess the detection rate of infective endocarditis (IE) in postoperative period in patients with aortic stenosis (AS) and analyze the impact of late diagnosis on disease outcomes. Material and methods . A retrospective analysis of the register of 1764 patients with AS, formed on the basis of transthoracic echocardiographic (echo) tests in2009-2011, was performed. During the 8-year follow-up period, 679 patients were operated on; IE was diagnosed in 131 people. Patients were divided into subgroups depending on the valve morphology and the time of IE verification before or after surgery. IE, first detected in the postoperative period, was considered as latent IE. Results . Among patients with AS, the proportion of people with IE was only 3,7%, however, pathomorphological examination revealed IE signs in 19,3%. In 58,8% of cases, IE was detected for the first time in the postoperative period. In 66,2% of cases, latent IE was diagnosed in patients with congenital heart disease (CHD) — bicuspid aortic valve (BAV). In the group of patients with known IE before surgery, there were lower levels of hemoglobin, erythrocytes and a higher level of creatinine. According to the results of a histological examination, inactive IE was diagnosed in 28% of cases. In 26,5% of patients stage 3 activity IE was defined, among which latent course was recorded in 16%. Single-agent antibiotic therapy (ABT) was carried out in 40,5% of patients, dual-agent ABT — in 50,0%, triple-agent — in 9,5%. The median duration of ABT was 14 days (7 to 42). The eight-year survival rate for patients with IE was 91,2%. Of the 9 deaths, only 5 (56%) had a diagnosis of IE before surgery. Conclusion . More than half of the patients operated on for AV defects had a latent course of IE and, as a result, late diagnosis, which could affect medium-term survival. Most of the people with latent IE included in the analysis had CHD-BAV, which requires the development of IE preventive measures in this patient population. Various approaches to the ABT of latent IE in clinical practice determine the relevance of additional studies aimed at unification the ABT approaches in this clinical setting.

Objective: Subclinical vascular damage evaluation is believed to be useful for cardiovascular risk précising in non-high risk patients. Different diagnostic tools suggested for vascular structure and function assessment, while there is a lack of data whether all these methods may reflect the wall damage in patients with dyslipidemia, diabetes mellitus and hypertension. The aim of the present study was to assess the association of traditional cardiovascular risk factors and markers of subclinical vascular damage depending on method. Design and method: 1592 apparently healthy participants aged 25–65 years were randomly selected from Saint-Petersburg inhabitants (a sample from ESSE-RF epidemiology survey. All participants signed informed consent and filled in the questionnaire regarding risk factors, concomitant diseases and therapy. Fasting lipids, glucose (Abbott Architect 8000) and vital signs were obtained. 191 patients were excluded from the risk estimation due to presence of cardiovascular complications. Cardio-ankle vascular index (CAVI), carotid-femoral pulse wave velocity (PWV-V) with amorphous probes and ankle brachial index (ABI) were measured by VaSera VS-1500 (Fukuda). Measurement of intima-media thickness (IMT) was performed by My Sono U6 (Samsung). Dyslipidemia was defined as cholesterol level>4,9 mmol/l, or LDL cholesterol >3,0 mmol/l, or medication prescribed for dyslipidemia. Hypertension and diabetes mellitus were defined according to current guidelines. Results: Majority of participants (955 (76,7%)) had normal values of vascular damage markers. Table 1. Parameters of vascular function in subjects with and without traditional risk factors.Conclusions: Dyslipidemia and hypertension seem to be associated with carotid atherosclerosis as well as with arterial stiffness while diabetes mellitus – only with carotid atherosclerosis. ABI does not reveal any association. Further investigations are needed to verify whether carotid ultrasound or CAVI gives more predictive value in these groups of patients (supported by the Grant 075-02-2018-57, 16.11.2018).

Objective:Obesity is a significant risk factor for cardiovascular diseases. It is known there is a subgroup among obese people who have normal insulin sensitivity, lipid profile and blood pressure – these subjects are generally considered metabolically healthy obese (MHO) individuals. Vascular age i

The system of the Naroch lakes, which includes the eutrophic Lake Batorino, the mesotrophic Lake Myastro, and the oligo-mesotrophic Lake Naroch, serves as a model object for the study of the factors initially influencing the state of a particular lake ecosystem affected by variable nutrient loading. Throughout the 1970s–2000s, these lakes have been going through the stages of anthropogenic eutrophication, deeutrophication, and benthification. A set of continuous data based on the seasonal means ​​of the eight parameters from each lake for the period 1978–2015 has been analyzed by Principal Component and Singular Spectrum Analysis (SSA, or Caterpillar). In addition, we consider the dynamics of the trophic index of each lake, which had been calculated earlier at the same data set. The first main component is the stability of the lake ecosystem under variable nutrient loading, which is inversely related to the trophic state of the water body. This component determines the condition of the Batorino, Myastro and Naroch lakes by 63, 65, and 43% respectively.

Aim. To assess the detection rate of infective endocarditis (IE) in postoperative period in patients with aortic stenosis (AS) and analyze the impact of late diagnosis on disease outcomes.Material and methods. A retrospective analysis of the register of 1764 patients with AS, formed on the basis of transthoracic echocardiographic (echo) tests in2009-2011, was performed. During the 8-year follow-up period, 679 patients were operated on; IE was diagnosed in 131 people. Patients were divided into subgroups depending on the valve morphology and the time of IE verification before or after surgery. IE, first detected in the postoperative period, was considered as latent IE.Results. Among patients with AS, the proportion of people with IE was only 3,7%, however, pathomorphological examination revealed IE signs in 19,3%. In 58,8% ofcases, IE was detected for the first time in the postoperative period. In 66,2% of cases,latent IE was diagnosed in patients with congenital heart disease (CHD) — bicuspidaortic valve (BAV). In the group of patients with known IE before surgery, there were lower levels of hemoglobin, erythrocytes and a higher level of creatinine. According to the results of a histological examination, inactive IE was diagnosed in 28% of cases. In 26,5% of patients stage 3 activity IE was defined, among which latent course was recorded in 16%. Single-agent antibiotic therapy (ABT) was carried out in 40,5% of patients, dual-agent ABT — in 50,0%, triple-agent — in 9,5%. The median duration of ABT was 14 days (7 to 42). The eight-year survival rate for patients with IE was 91,2%. Of the 9 deaths, only 5 (56%) had a diagnosis of IE before surgery.Conclusion. More than half of the patients operated on for AV defects had a latent course of IE and, as a result, late diagnosis, which could affect medium-term survival. Most of the people with latent IE included in the analysis had CHD-BAV, which requires the development of IE preventive measures in this patient population. Various approaches to the ABT of latent IE in clinical practice determine the relevance of additional studies aimed at unification the ABT approaches in this clinical setting.

The aim of the study was to evaluate the contribution of psychoemotional factor in arrhythmogenesis in patients with idiopathic ventricular arrhythmias (VA) on the basis of analysis of the results of various mental stress-tests (MT). Material and methods. 66 patients with idiopathic VA and anxiety neurotic disorders (AND) were included in the study after careful examination. MT were performed all patients according to the study protocol. Results. According the data of statistical analysis there were not stasistically significant differences in the baseline levels of hemodynamic parameters in the perid of rest between MT. Thus, the sequence of the test does not affect its result. According comparative analysis there were statistically significant differences between MT only in the hemodynamic parameters changes and not in the change of VA. Comparative analysis between men and women in the changes of hemodynamic parameters and VA during the MT did not reveal gender differences. The conclusion . Use of MT allows to evaluate the contribution of psyhoemotional factor in the genesis of VA in patients with idiopathic arrhythmia and AND. MT should be included in the algorithm for examining patients with VA because of the different effects of psychoemotional and physical stress, like a trigger, on the ventricular ectopic focus.

Аннотация. Данная статья представляет результаты сравнительного эмпирического исследования, посвященного выявлению различий в уровне неудовлетворенности различными аспектами жизнедеятельности и социального общения учащихся вузов и ссузов Санкт-Петербурга; эмпирической базой выступают данные массового опроса петербургских студентов. Результаты исследования позволяют зафиксировать значимые различия и актуализируют необходимость дальнейших исследований среди студенческой молодежи в ее целостности. Ключевые слова: Студенческая молодежь, сравнительный анализ, система высшего образования, система среднего профессионального образования, уровень неудовлетворенности.

PURPOSE:The study purpose was to investigate and evaluate factors of career satisfaction among neurosurgeons in the Russian Federation.MATERIAL AND METHODS:During the pilot study, 217 neurosurgeons in the Russian Federation were surveyed in 2016. The survey was conducted through an anonymous voluntary questionnaire. The questionnaire consisted of four sections: 1) demographic data; 2) evaluation of professional stress factors; 3) characteristics of job satisfaction; 4) quality of life indicators. Responses in ordinal scales were evaluated using one-dimensional frequency analysis; factors related to career satisfaction were assessed using correlation and regression analyses.RESULTS:More than 80% of the respondents were males under the age of 40, ordinary doctors, without a scientific degree, with less than 15 years of work experience, performing less than 150 operations a year, and receiving wages less than 60 thousand rubles per month. The most common negative job-related factors of occupational stress included a large amount of work with medical records and insufficient wages. Only 51% of neurosurgeons were in general satisfied with their career. The greatest dissatisfaction in more than 55% of respondents was associated with the lack of time for personal development. More than 83% of respondents considered their legal protection insufficient. A correlation analysis revealed the greatest correlation (about 0.4) between career satisfaction and opportunities for professional growth as well as between mutual understanding with colleagues and confidence in the future. In addition, a regression analysis revealed the following factors: time for doing science, confidence in a stable salary, work on weekends, knowledge of English, and insufficient supply of consumables.CONCLUSION:Career satisfaction of the neurosurgeon depends mainly on working conditions and confidence in career prospects.

Singular Spectrum Analysis (SSA) has been used to decompose continuous series of data on certain characteristics of Lake Naroch’ ecosystem during the vegetative seasons of years 1978–2015 into a long-time trend, a periodic component, and a residue not amenable to decomposition. The contribution of each component to changes in this variable has been assessed. The trends accounted for 78–97% of parameter variability, and the periodic components accounted for 2.5–15%. The fluctuations of phytoplankton and zooplankton biomass dynamics were the most diverse, and the contribution of these components was the greatest (15 and 8%, respectively). The periodic components in the changes of all parameters could be divided into four groups according to period duration (17–22, 7–15, 4–7, and less than 4 years). Multidimensional factor analysis of seven biotic parameters was performed in order to identify fluctuations in the ecosystem. Five major factors accounting for 93.6% of ecosystem changes together were identified, and each factor variable was subjected to SSA analysis. The period durations were similar for the oscillatory components identified. The first factor was interpreted as a trophic status of the water body, the second was taken to be the geographical location that defines the amount of solar radiation energy available, the third was taken to be the availability of biogenic elements (phosphorus in particular), and the fourth was interpreted as specific developmental cycles of live components of the ecosystem.

Aim. To study the role of prognostic oral high-dose dexamethasone suppression test (HDDST) and pituitary MRI in the prognosis of Cushing’s disease (CD). remission after transsphenoidal endoscopic surgery (TSS). Material and methods. 59 patients with Cushing’s disease (9 men, 50 women, mean age 40 years (15-72) underwent TSS were included. Before the TSS HDDST and pituitary MRI were performed in all cases. Postoperative examination was done one year after surgery. Remission criteria were: combination of normal midnight serum cortisol levels, normal 24 hour urine free cortisol (UFC) excretion and serum cortisol suppression less than 50 nmol/l in 1-mg dexamethasone test or secondary adrenal insufficiency (the need for glucocorticoid replacement). The optimal threshold value of serum cortisol suppression in the HDDST for prediction of CD remission after TSS was calculated by ROC-analysis. Results. One year after surgery CD remission was confirmed in 39 patients, whereas in 20 patients hypercortisolism persisted. The optimal threshold value of serum cortisol suppression in the HDDST for prediction of CD remission after TSS was 72%. Test’s sensitivity and specificity were 82% and 84%, respectively. The probability of wrong prediction was 17% (p=0,0001). In our study, the results of TSS did not correlate with MRI adenoma size.

Introduction. The role of healthy lifestyles in the prevention of chronic non-communicable diseases is very important. Lifestyle of medical personnel, especially future doctors, may have great influence on healthy lifestyle compliance of patients. The objective of our study was to compare the prevalence of cardiovascular risk factors among doctors and students of medical educational institutions who underwent screening during The Russian Congress of Cardiology in 2016. Material and methods. During the Russian National Congress of Cardiology (Ekaterinburg, 20-23 September 2016), the participants were screened for the presence of cardiovascular risk factors. Participants filled out the questionnaire on the social status, nutrition, physical activity, smoking status, frequency of alcohol consumption, therapy. Anthropometry was performed in accordance with standard procedures. Blood pressure (BP) was measured on the right hand in a sitting position after a 5-minute rest with the automatic tonometer OMRON (Japan). The level of cholesterol and blood glucose was measured by express method using EasyTouch® GCHb (Taiwan). Results. The screening included 535 participants aged 18-78 years, the majority of whom (80 %) were women. There were 193 students, 342 doctors. Compared with students, doctors were significantly more likely to have sufficient intake of vegetables, fruits (50 vs 70 %) and fish (76 vs 88%), p<0.05, and comparable levels of salt overtaking (39 vs 34 %) and hypodynamia (35% in both groups). Only 10% of students and 7% of doctors smoked. The expected increase in the prevalence of biological risk factors in accordance with the age was significantly more common in doctors: hypercholesterolemia (63 vs 30 %), hyperglycemia (25 vs 14 %), hypertension (36 vs 5 %), obesity (according to WC – 45 vs 10 %, according to BMI – 19 vs 6 %), p<0.05. The profile of the most common risk factors did not differ among doctors and students: hypercholesterolemia and overweight in both groups took the leading positions. Also in accordance with the age, there were more often complaints of snoring-24% in doctors and 7% in students.Conclusion. The students had a less favorable profile of behavioral factors in diet compared to doctors, and despite of the expected age differences, a high prevalence of hypercholesterolemia and overweight was revealed. Obviously, it is necessary to strengthen educational work in this area at the stage of training of nurses and doctors to preserve the health of both medical personnel and their patients.