Princess Nourah Bint Abdulrahman University (PNU; Arabic: جامعة الأميرة نورة بنت عبد الرحمن)is a public women's university located in Riyadh, the capital of Saudi Arabia. It is the largest women's university in the world.The university offers diplomas, bachelor and postgraduate degrees. It has 34 colleges in the city of Riyadh and in the neighbouring cities, an Arabic Language Institute (for non-speakers of Arabic), a Deanship of Community Service and Continuous Education, and a Community College. It has more than 5,000 academic and administrative staff.
The increasing interest in spinel ferrites due to their notable characteristics including elevated electrochemical stability, redox states and pseudocapacitive activity which make them suitable for application in supercapacitors. The present research involves synthesis of NiFe2O4@g-CN electrode material using hydrothermal route. The various characterization techniques including, electrochemical and physical were used for NiFe2O4 and NiFe2O4@g-CN nanocomposite. The fabricated NiFe2O4@g-CN nanosheet showed exceptional specific capacitance of 740 F/g energy and power density were 38 Wh/Kg and 305 W/Kg respectively at 1 A/g determined from galvanostatic charge discharge plot. The charge transfer resistance (Rct) value of NFO@g-CN (0.23 Ω) exhibited lower value than NFO (0.35 Ω) and g-CN (0.27 Ω). The electrochemical stability test revealed that after 5000th cycle NiFe2O4@g-CN material maintains a very stable structure. Therefore, improvements in electrochemical efficiency of NiFe2O4 because of inclusion of graphitic carbon nitride which provided larger surface area, synergistic interaction and large number of active sites. These finding indicates that electrodes materials have potential material for energy storage device and it can further used in toward water splitting and various energy storage equipment’s.
Co-precipitation method was used as a quick and effective way to elaborate the Mg and Cu co-doped TiO2 (MgCu/T) nanoparticles. The formation of a single phase (anatase) with a tetragonal structure of nano-crystallized MgCu/T was confirmed by X-ray diffraction (Card No. 89–4203). Experimental results indicate that the synthesized MgCu/T nanoparticles are nanometric, ranging from 12 to 25 nm, consistent with the findings from SEM images. Additionally, the UV–Vis reflectance spectra showed that MgCu/T nanoparticles possess strong absorption properties in the UV–visible region. Hence, the photocatalytic activities showed that the 4 mol
Synthetic dyes, such as methylene blue (MB), are increasingly becoming sources of water pollution and require better treatment strategies. This study describes an eco-friendly method for methylene blue degradation using green synthesized iron oxide nanoparticles form Ureibacillus chungkukjangi. This bacterium was isolated from clinical samples and identified using 16S rRNA gene amplification and sequenced using Sanger sequencing technology. The identified Ureibacillus chungkukjangi was submitted to NCBI with NCBI accession no. PQ568249.1. The secondary metabolites of the bacteria acted as capping agents to both reduce and stabilize the nanoparticle synthesis. The nanoparticle synthesis was achieved by the addition of iron chloride solution as a precursor to bacterial metabolites, forming the orange-brown solution to dark brown that showed initial signs of nanoparticle synthesis that were verified with UV–Vis Absorption spectra giving peaks at 380 nm. In FTIR spectra of the range examined (570–630 cm⁻1), Fe–O bonds were observed, which confirms that biofunctionalization of the surface had been done. Also observed were O–H, C–H, C=O, and C–O functional groups of surfaces biofunctionalization. Furthermore, SEM analysis showed the particle size ranging from 50 to 400 nm while massively polygonal, where EDX analysis further confirmed the presence of iron in the sample. The degradation studies conducted over 15 days showed that there was a total of 89
The rise of antibiotic-resistant Bacillus cereus strains, particularly those carrying the blaOXA gene encoding oxacillinase-type β-lactamase, has significantly limited treatment options for foodborne illnesses. This study aimed to identify blaOXA-positive Bacillus cereus from environmental samples and evaluate AI-optimized phytochemicals as novel inhibitors of the blaOXA enzyme. Soil-derived bacterial isolates were identified via 16S rRNA gene amplification and Sanger sequencing. Antibiotic susceptibility was assessed using the disc diffusion method. The blaOXA gene was amplified and sequenced, followed by phylogenetic analysis. The blaOXA protein was modeled using AlphaFold3 and validated by the Ramachandran plot and ERRAT. Thirty phytochemicals were screened using molecular docking against blaOXA protein. Piperine emerged as the top candidate and was optimized using the WADDAICA AI tool. AI-modified derivatives were evaluated through docking, ADMET, toxicity, density functional theory (DFT), molecular dynamics (MD) simulations, and pharmacophore analysis. The isolated strain MBBL37 was confirmed as B. cereus (NCBI Accession: PVO14952.1), resistant to ampicillin and cefoxitin. The blaOXA gene (632 bp; Accession: PV535213.1) showed phylogenetic similarity with Enterobacter and E. coli, suggesting potential horizontal transfer. The predicted blaOXA protein demonstrated high stereochemical reliability (87.8
Vibrio fluvialis is an emerging foodborne pathogen causing gastroenteritis and extraintestinal infections, representing a significant public health concern due to rising antimicrobial resistance and the absence of an approved vaccine. This study aimed to design a multi-epitope subunit vaccine against V. fluvialis using immunoinformatics and a standard multi-epitope vaccine design pipeline. Two surface-exposed immunogenic membrane proteins, ATP-dependent zinc metalloprotease FtsH and lytic murein transglycosylase F, were selected as antigenic targets. Ten epitopes, including four MHC class I, four MHC class II, and two B-cell epitopes, were predicted and assembled into a 246 amino acid vaccine construct. The construct showed an antigenicity score of 0.8610. Population coverage analysis indicated that these epitopes could potentially cover 99.97
