OBJECTIVE:To evaluate the clinical efficacy of compound Kushen injection for cancer-related fatigue in patients with lung cancer after undergoing chemotherapy.METHODS:A total of 106 patients with non-small cell lung cancer(NSCLC) presenting cancer-related fatigue after chemotherapy were randomly assigned to either treatment group(compound Kushen injection plus symptomatic treatment,n = 52) or control group(symptomatic treatment alone,n = 54).The short-term efficacy and adverse reactions in the two groups were followed and the Brief Fatigue Inventory(BFI) score and Karnofsky score were evaluated.RESULTS:The incidence rates of gastrointestinal reaction and bone marrow suppression in the treatment group were lower than in the control group.BFI score and Karnofsky score in the treatment group were significantly higher than in the control group,showing significant differences between the two groups(P 0.05).CONCLUSION:Treatment of cancer-related fatigue in patients with lung cancer after chemotherapy using compound Kushen injection resulted in improvement of patients' quality of life and alleviation of cancer-related fatigue.

目的:探讨正压无针连接式留置针在肿瘤患者中应用效果。方法:180例需要输液治疗的肿瘤住院患者,随机分为正压针组及普通针组(各90例),正压针组采用正压无针连接式留置针,普通针组采用普通夹留置针,观察两组穿刺成功率、留针时间和并发症发生率。结果:两组穿刺成功率无统计学(P>0.05),正压针组留针时间长于普通针组(P<0.05),并发症发生率低于普通针组(P<0.05)。结论:正压无针连接式留置针能够减少并发症发生率,提高留置针使用效果。

肿瘤科护士的工作对象是重症患者及生命需要紧急救治的患者,护理工作包含脑力劳动与体力劳动2个方面,护理工作的性质决定了护士必须经常面对患者、家属、医生及其他人,在绿色通道畅通的同时,这些因素都会使护士在躯体上、心理上承受着明显的压力,并影响到其身心健康和工作质量[1].

目的探讨异长春花碱药物非穿刺伤外渗的原因及预防措施.方法回顾性分析我科近2年使用NP方案化疗的20例患者.结果3例患者局部皮肤发生蜂窝组织炎,4例患者发生静脉炎.结论对引起非穿刺伤药物外渗的化疗药,要严格遵守化疗药物操作规程,合理使用血管,重点预防,重视追踪观察.

消化道肿瘤尤其是食管癌的家族聚集现象已被公认,但临床病例报告不多,对其产生的原因并未形成共识,在1992年1月～1999年12月间收集到具有明显家族聚集现象的食管癌家族32个,分析探讨具有家族聚集性的食管癌的发病特征,以便早期发现,早期诊断. 1 材料与方法 收集1992年1月～1999年12月期间具有家族聚集现象的食管癌家族32个共138位患者,所有病例在3代,3代中至少有3个食管癌(或贲门癌)患者,家族病史主要由患者或家族其它成员提供,并经家族第二成员证实,其中仅部分患者取得病理诊断,其余只获临床诊断,是根据典型的进行性吞咽困难和发展到食管梗阻等判断为食管癌.