As an integral component of China's standardization system, rehabilitation medicine association standards play a pivotal role in regulating clinical practice, ensuring care quality, and nurturing rehabilitation professionals. Grounded in the Standardization Law of the People's Republic of China and drawing on the practical experience of standardization work by the Chinese Association of Rehabilitation Medicine, the formulation of the Guidelines for Standardization Work of Rehabilitation Medicine Association Standards aims to establish a systematic framework for the development of these standards and promote the standardized development of the rehabilitation medicine field. The guidelines detail the principles for the formulation of rehabilitation medicine association standards, scope of application, the qualifications of the entities involved, and the technical specifications. They highlight the importance of combining evidence-based practice with clinical experience in the development of these standards, clarify the fundamental principles of openness, transparency, and consensus, and outline the complete workflow from proposal, project approval, drafting, and solicitation of comments to final publication and periodic review, providing specific recommendations for the dissemination of the standards. By enhancing the quality of rehabilitation medicine association standards, the Guidelines will promote the standardization of rehabilitation medical services and advance the development of rehabilitation medicine in China.

As an integral component of China's standardization system, rehabilitation medicine group standards play a pivotal role in regulating clinical practice, ensuring care quality, and nurturing rehabilitation professionals. Grounded in the Standardization Law of the People's Republic of China and drawing on the practical experience of the Chinese Association of Rehabilitation Medicine, the Guidelines for the Standardization of Rehabilitation Medicine Group Standards aim to establish a systematic framework for the development of these standards and foster the field's regulated development. The Guidelines detail the principles for the formulation of rehabilitation medicine group standards, their scope, the qualifications of the entities involved, and the technical specifications. They highlight the importance of combining evidence-based practices with clinical experience in the development of these standards, articulate the foundational principles of openness, transparency, and consensus, and outline the comprehensive workflow from proposal to final publication and periodic review, providing concrete recommendations for the dissemination of the standards. By enhancing the quality of rehabilitation medicine group standards, the Guidelines will promote the standardization of rehabilitation medical services and advance the development of rehabilitation medicine in China.

With the gradual increase in the application of lower limb robots in motor function rehabilitation, there is a need to standardize the clinical application of lower limb rehabilitation robots in China. This consensus integrates the characteristics of lower limb rehabilitation robots applications in the treatment for patients with hemiplegia, paraplegia, cerebral palsy, and other common lower limb dysfunctions in China. In addition, referencing the latest research, this consensus elaborates on the working principles, classification, clinical application (indications and contraindications, working parameters and operating procedures, safety), and recommendations on clinical application (hemiplegia, paraplegia, musculoskeletal diseases, childhood diseases and other systemic diseases) when using lower limb rehabilitation robots in the current context. Lower limb rehabilitation robots are well-suitable for patients with walking difficulties and long-term bedridden condition. According to the patient's posture during rehabilitation training, they can be classified into sitting or supine robots, upright robots, and assisted upright robots. The treatment parameters of lower limb robots are determined by the patient's weight and lower limb's length, range of motion, and muscle strength, among which guiding force, walking speed, and anti-gravity are important parameters that need to be adjusted. There are many factors that affect the safety using of lower limb rehabilitation robots, and it is usually necessary to evaluate the safety by monitoring the occurrence of adverse events during robot training. Studies have shown that combining lower limb rehabilitation robot training with conventional rehabilitation therapy or emerging rehabilitation technologies such as virtual reality and transcranial direct current stimulation improves motor function in stroke patients with hemiplegia. However, determining whether its training effect is superior to conventional rehabilitation therapy requires further clinical study (high-level evidence). Studies have also shown that lower limb rehabilitation robot training can improve walking function (medium to high-level evidence), cardiopulmonary function (low to medium-level evidence), lower urinary tract function (low-level evidence), and balance function (low to medium-level evidence) in paraplegic patients. Medium-level evidence suggests that paraplegic patients with lower limb spasms can undergo lower limb rehabilitation robot training. Studies have shown that lower limb robot training can improve the pain, range of motion, muscle strength of lower limb, and walking ability of patients with musculoskeletal diseases. It is mainly used in post-total knee arthroplasty (medium-level evidence), post-total hip arthroplasty (medium to low-level evidence), and osteoarthritis (medium to low-level evidence). Studies have shown that lower limb rehabilitation robot assisted gait training (medium-level evidence) and joint activity training (low-level evidence) are beneficial for improving lower limb function, gross movement, and gait in children. Lower limb robot assisted gait training combined with exercise therapy (medium-level evidence) can help improve walking speed, endurance, balance ability, and other abilities in children.

目的:分析有氧运动及呼吸训练对慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)肺功能的影响。方法:选择2020年4月至2020年12月我院收治的95例稳定期COPD患者随机分为观察组50例、对照组45例。对照组患者接受健康宣教及规范COPD治疗，观察组在此基础上接受有氧运动联合呼吸训练治疗。两组连续治疗3个月，比较治疗前后肺功能指标变化。结果:治疗后，两组PEF、FEV1、FEV1/FVC、BODE(COPD患者生存状况评估)指标及指数均较治疗前显著改善(P<0.05)，观察组改善程度显著(P<0.05)；观察组hs-CRP、IL-6、TNF-α水平及圣乔治呼吸调查问卷(St.George′s Respiratory Questionnaire, SGRQ)评分较治疗前下降，与对照组相比存在统计学差异(P<0.05)；观察组治疗依从性及治疗满意度高于对照组(P<0.05)。结论:有氧运动联合呼吸训练可提升稳定期COPD肺功能，改善BODE指标及指数，降低机体炎症水平，提高治疗满意度和生活质量，治疗依从性高。

近年来,国内围绕国际功能、残疾和健康分类(Interna-tional Classification of Functioning,Disability and Health,ICF)临床应用方面的研究逐年增多[1-3],而《国际功能、残疾和健康分类(ICF)专家共识》的发表[4],又推动了 ICF及其核心组合如康复组合(ICF rehabilitation set,ICF-RS)的临床应用及标准的编制[5-6].本文仅就ICF及ICF-RS在国内的应用作一介绍,旨在进一步推动ICF及ICF-RS在国内临床的应用及研究.

We aimed to explore whether motor function and activities of daily life (ADL) could be improved with the application of visual deprivation in two patients with Pusher syndrome complicated by hemispatial neglect after right basal ganglia stroke. We assessed two stroke patients suffering from severe motor disturbances, both tilting heavily to the left, with diagnoses of Pusher syndrome and left hemispatial neglect. Vision in the left eye was deprived using patches during clinical rehabilitation. Motor function promotion was confirmed using the Burke Lateropulsion Scale (BLS), Fugl–Meyer Balance Scale (FMBS), and Holden grade (HG), while the Barthel index (BI) assessed ADL immediately and 1 week after intervention. Both patients regained standing balance immediately using visual deprivation, as well as walking ability, although both scored 0 on the FMBS and HG. After 1 week of treatment, one patient increased to 11 and 3 on the FMBS and HG, respectively, while the BLS score decreased from 12 to 2, and the ADL increased from 23 to 70. The other patient demonstrated increases to 10 and 3 on the FMBS and HG, respectively, with the BLS decreasing from 13 to 3, and the ADL increasing from 25 to 60. Therefore, in the rehabilitation treatment of Pusher syndrome complicated by hemispatial neglect due to basal ganglia stroke, visual deprivation can significantly improve motor function and shorten the treatment course.

目的:探讨运动贴扎技术联合体外冲击波改善足底筋膜炎疼痛程度及功能的临床疗效.方法:本研究纳入63例足底筋膜炎患者,随机分为运动贴扎技术组(KT)、体外冲击波组(ESWT)及联合治疗组,三组患者均予以牵伸训练为基础.采用疼痛视觉模拟评分(visual analogue scale,VAS)、肌骨超声、美国矫形足踝协会踝与后足功能评分表(American Orthopaedic Foot and Ankle Society,AOFAS)评估患者的足跟疼痛程度、足底筋膜厚度及足踝的功能状态.比较三组患者治疗后2周、治疗后4周的差异.结果:治疗后2周,三组患者在VAS、AOFAS评分方面均较治疗前改善(P＜0.01),在足底筋膜厚度方面,体外冲击波组及联合治疗组较治疗前有显著性差异(P＜0.01);与KT组比较,ESWT组和联合治疗组在VAS、足底筋膜厚度及AOFAS方面均明显改善(P＜0.05),但两组之间VAS、足底筋膜厚度差异无显著性意义(P＞0.05);而在AOFAS方面,联合治疗组改善更显著(P＜0.05).治疗后4周,三组患者在VAS、足底筋膜厚度、AOFAS评分均较治疗前改善(P＜0.01);三组间比较,在VAS、足底筋膜厚度及AOFAS评分方面,联合治疗组较体外冲击波组、运动贴扎技术组均改善更显著(P＜0.05).结论:运动贴扎技术和体外冲击波治疗均可改善足底筋膜炎患者的疼痛程度和功能,联合治疗效果更明显.

肌内效贴技术是指将弹性贴布以特定方法贴于体表产生力学及神经生理学效应,从而达到保护肌肉骨骼系统、促进运动功能或其他治疗目的.近年来,除肌肉骨骼疾患外,该技术在神经及儿科康复等领域也有较多应用,取得了一定的临床疗效,但其起效机制仍待关注及系统探究.该文在评述国内外学者近年来肌内效贴技术的临床研究及应用经验的基础上提出了一些思考与展望,旨在抛砖引玉,为该技术临床应用及机制的研究提供借鉴与参考.

目的 探讨膝关节骨肉瘤切除伴肿瘤型假体置换术后影响患者功能的因素.方法 采用问卷调查法调查2019年1月到2020年8月在我院骨科接受膝关节骨肉瘤切除伴肿瘤型假体置换术后患者20例,应用骨与软组织肿瘤术后功能重建评估系统[5](MSTS)评估患者术后功能,同时采集患者的一般人口学特征信息如性别、身高、文化程度等,以及临床评估资料如康复治疗、并发症、股四头肌肌力等.采用单因素和多因素线性回归分析影响术后功能的因素.结果 术后功能得分为(22.4±5.3)分;膝关节活动度为(97.3±14.0)度;术后日常生活能力得分为(94.5±7.1)分.单因素分析发现并发症(t=5.094,P<0.05)、术后时间(t=-2.890,P<0.05)、肿瘤部位(t=2.077,P<0.05)和康复治疗(t=-3.009,P<0.05)是影响术后功能的因素;多因素研究发现并发症(t=-2.827,P<0.05)、术后时间(t=2.173,P<0.05)和康复治疗(t=2.442,P<0.05)是术后功能的独立影响因素.结论 并发症、康复治疗和术后时间是膝关节骨肉瘤患者肿瘤型假体置换术后功能的主要影响因素.减少并发症和开展康复治疗可以促进术后功能恢复.

BACKGROUND Ischemia/reperfusion (I/R) refers to situations where blood is perfused into ischemic or hypoxic tissues, potentially resulting in an inflammatory response and oxidative injury. OBJECTIVES This study was conducted to explore the pathogenesis of I/R injury. MATERIAL AND METHODS GSE82146 was extracted from the Gene Expression Omnibus, consisting of 15 complete global brain ischemia (CGBI) reperfusion hippocampus samples and 12 non-ischemic control (NIC) hippocampus samples. The differentially expressed genes (DEGs) between the CGBI and NIC samples were selected using LIMMA package, and were then analyzed with weighted gene co-expression network analysis (WGCNA). Using DAVID software, the DEGs in significant modules were run through enrichment analysis. The DEGs in significant modules were merged, and then a protein-protein interaction (PPI) network was built for them using Cytoscape software. After miRNAs and transcription factors (TFs) were predicted for the DEGs using the WebGestalt tool, a TF-miRNA-target regulatory network was built using Cytoscape software. Furthermore, quantitative real-time polymerase chain reaction (qRT-PCR) analysis was conducted to detect the levels of key genes. RESULTS There were 390 DEGs in the CGBI samples. Based on WGCNA, brown and turquoise modules were screened as CGBI-associated modules. In the PPI network, key nodes HSP90AA1 and HSPA5 were able to interact with each other. In the regulatory network, MYC, HSF1 and miR-22 had higher degree values. Moreover, HSPA5 was targeted by MYC in the regulatory network. In addition, upregulated HSPB1 and HMOX1, as well as downregulated NR4A2, were confirmed with qRT-PCR analysis. CONCLUSIONS HSPB1, HMOX1 and NR4A2 were the key genes correlated with I/R injury. Additionally, HSP90AA1, HSPA5, MYC, HSF1, and miR-22 might be related to the pathogenesis of I/R injury.

Objective:To compare the efficacy of series casting with different timings after botulinum toxin injection among equinus children with spastic cerebral palsy.Methods:Sixty-three equinus children with spastic cerebral palsy were randomly divided into a control group and an experimental group. After being injected with botulinum toxin type A, 4 weeks of series casting was applied immediately in the control group, while in the experimental group it was applied 2 weeks later. Both groups were given basic rehabilitation therapy including heel walking, kicking balls, single-leg standing, standing platform training and balance training. The modified Tardieu scale, three-dimensional gait analysis, gross motor function measure 88 (GMFM-88) and a self-made questionnaire were used to evaluate muscle tone, spasticity, gait parameters, standing and walking before the treatment and 2 and 6 months afterward.Results:Immediately after the treatment there was a significant improvement in both groups′ average MTS scores (R1, R2, R1-R2 with knee extension and flexion), dorsiflexion at initial contact, peak dorsiflexion in the stance and swing phases, and dimension D (standing), and also in their average GMFM-88 (walking) scores. Two and six months later the experimental group′s average MTS scores, peak dorsiflexion in the stance phase, and dimension D (standing) score in the GMFM-88 (walking) had improved significantly compared with the control group′s averages. However, no significant differences were observed between the two groups in any of the other measurements after the treatment.Conclusion:Delaying series casting after botulinum toxin A injection can significantly reduce tone and spasticity in the plantarflexors, improve the range of motion and functioning of the ankle, and alleviate the discomfort and pain caused by series casting.

Objective: To compare the efficacy of kinesio taping on chronic non-specific low back pain with that of other general physical therapies. Methods: Relevant studies published up to 31 July 2018 were searched in electronic databases (PubMed, Web of Science, Science Direct, Physiotherapy Evidence Database (PEDro), Cochrane Library, Wan-fang Data, Vip Data and China National Knowledge Infrastructure). The quality of included studies was assessed using a risk of bias assessment tool, as recommended by the Cochrane Collaboration. Data from visual analogue scales and Oswestry Disability Index were extracted as selected outcome indicators. Tests of heterogeneity were performed. Weighted mean difference (WMD) data with its 95% confidence intervals (95% CI) were used as a measure of effect sizes, in order to pool the results from each included study using either a fixed or random effects model (where appropriate and possible). Results: Eight studies fulfilled the inclusion and exclusion criteria. The quality of included studies was moderate. Patients with chronic non-specific low back pain in the kinesio taping group achieved better pain relief (WMD= -1.22; 95% CI -1.49 to -0.96, I-2 = 91%, p< 0.00001) and activities of daily living (WMD= -7.11; 95% CI -8.70 to -5.51, I-2 =77%, p < 0.0001) than those in the control group. Conclusion: Kinesio taping may be a new, simple and convenient choice for intervention in low back pain. In the future, we can measure the efficacy about kinesio taping via clinical application in order to prove the possibility of treatment for low back pain.

To explore the expression changes of genes and the pathological processes-related genetic information in Parkinson's disease (PD) model induced by rotenone. The microarray data set "GSE37178" was downloaded from Gene Expression Omnibus database. Differentially expression genes (DEGs) at different concentration and time points were examined and clustered using Mfuzz. Functional enrichment was analyzed with The Database for Annotation, Visualization and Integrated Discovery. Search Tool for the Retrieval of Interacting Genes was used to perform the protein-protein interaction (PPI) networks, and functional module analysis of PPI was constructed with Cytoscape. Moreover, transcription factors (TFs) and microRNA (miRNA) target were screened with TRRUST and WebGestalt GAST, respectively. In total, 680 DEGs were examined in the group with rotenone treatment. Clustering analysis revealed that 115 genes presented a consistent rising trend, and 138 genes presented a falling trend. Functional enrichment analysis uncovered that the upregulated genes associated with "type I interferon signaling pathway," and the downregulated genes were related to "proteasome-mediated ubiquitin-dependent protein catabolic process." The PPI network included 156 nodes and 298 interactions, and ISG15, RRM2, FBXW11, and FOXM1 were the hub genes. Meanwhile, 38 TF-target and 269 miRNA-target interactions were obtained; the mRNAs of the MIR-181 family have more target genes, such as TRIM13. Our study showed that aberrant expression of ISG15, RRM2, FBXW11, FOXM1, and MIR-181 family were associated with pathological processes in PD, and they could be the research focuses to further investigate the mechanism of PD.

The present study aimed to identify the genes and underlying mechanisms critical to the pathology of spinal cord injury (SCI). Gene expression profiles of spinal cord tissues of trkB.T1 knockout (KO) mice following SCI were accessible from the Gene Expression Omnibus database. Compared with trkB.T1 wild type (WT) mice, the differentially expressed genes (DEGs) in trkB.T1 KO mice following injury at different time points were screened out. The significant DEGs were subjected to function, co‑expression and protein‑protein interaction (PPI) network analyses. A total of 664 DEGs in the sham group and SCI groups at days 1, 3, and 7 following injury were identified. Construction of a Venn diagram revealed the overlap of several DEGs in trkB.T1 KO mice under different conditions. In total, four modules (Magenta, Purple, Brown and Blue) in a co‑expression network were found to be significant. Protein tyrosine phosphatase, receptor type C (PTPRC), coagulation factor II, thrombin (F2), and plasminogen (PLG) were the most significant nodes in the PPI network. 'Fc γ R‑mediated phagocytosis' and 'complement and coagulation cascades' were the significant pathways enriched by genes in the PPI and co‑expression networks. The results of the present study identified PTPRC, F2 and PLG as potential targets for SCI treatment, which may further improve the general understanding of SCI pathology.

Glioblastoma multiforme (GBM) is one of the most lethal and damaging types of human cancer. The current study was conducted to identify differentially methylated genes (DMGs) between GBM and normal controls, and to improve our understanding of GBM at the epigenetic level. The DNA methylation profile of GBM was downloaded from the Gene Expression Omnibus (GEO) database using the accession number GSE50923. The MethyAnalysis package was applied to identify DMGs between GBM and controls, which were then analyzed by functional enrichment analysis. Protein-protein interaction (PPI) networks were constructed using the hypermethylated and hypomethylated genes. Finally, transcription factors (TFs) that can regulate the hypermethylated and hypomethylated genes were predicted, followed by construction of transcriptional regulatory networks. Furthermore, another relevant dataset, GSE22867, was downloaded from the GEO database for data validation. A total of 476 hypermethylated and 850 hypomethylated genes were identified, which were mainly associated with the functions of 'G-protein-coupled receptors ligand binding', 'cytokine activity', 'cytokine-cytokine receptor interaction', and 'D-glutamine and D-glutamate metabolism'. The hypermethylated gene neuropeptide Y (NPY) and the hypomethylated gene tumor necrosis factor (TNF) demonstrated high degrees in the PPI network. Forkhead box protein A1 (FOXA1), potassium voltage-gated channel subfamily C member 3 (KCNC3) and caspase-8 (CASP8) exhibited high degrees in the transcriptional regulatory networks. In addition, the methylation profiles of NPY, TNF, FOXA1, KCNC3 and CASP8 were confirmed by another dataset. In summary, the present study systematically analyzed the DNA methylation profile of GBM using bioinformatics approaches and identified several abnormally methylated genes, providing insight into the molecular mechanism underlying GBM.

OBJECTIVE:On the basic therapy, to assess the clinical effects of dynamic scalp acupuncture, scalp acupuncture combined with proprioceptive neuromuscular facilitation (PNF) therapy and simple PNF therapy for upper limb motor impairment in ischemic post-stroke spastic hemiplegia.METHODS:A total of 90 cases were randomly assigned into a PNF group, a dynamic scalp acupuncture group and a scalp acupuncture group, 30 cases in each group. Basic therapy and PNF therapy were applied in the three groups. PNF therapy was used during scalp acupuncture in the dynamic scalp acupuncture group. PNF therapy was applied after scalp acupuncture in the scalp acupuncture group. The points were the upper 1/5 and middle 2/5 of Dingnieqianxiexian (MS 6) and Dingniehouxiexian (MS 7) at the lesion side, the hemiparalysis contralateral side. The treatment was given for 6 months, once a day and 1 month as a course. The modified Ashworth scale (MAS), the Fugl-Meyer motor assessment (FMA) and Barthel index (BI) were observed before treatment and 2 weeks, 1 month, 3 months, and 6 months after treatment.RESULTS:The MAS 1 month, 3 months and 6 months after treatment were improved compared with those before treatment in the three groups ( all P<0.05), and the MAS results in the dynamic scalp acupuncture group were better than those in the PNF and scalp acupuncture group (all P<0.05). The FMA and BI scores 1 month, 3 months and 6 months after treatment were higher than those before treatment (all P<0.05). The FMA Scores in the 3 time points and after treatment in the dynamic scalp acupuncture group were higher than those in the other two groups (all P<0.05).CONCLUSION:PNF therapy during scalp acupuncture can relieve the spasmodic condition of patients with upper limb motor impairment in ischemic post-stroke spasmodic hemiplegia, and improve the limb function and life activity, which is better than PNF therapy after scalp acupuncture and simple PNF therapy.

Objective To observe the clinical efficacy of modified kinesio taping of integrated Chinese and western medicine in the treatment of knee osteoarthritis.Methods 150 patients with knee osteoarthritis were randomly divided into the external treatment group of Chinese medicine(Chinese medicine group),external treatment group of western medicine(western medicine group) and integrated Chinese and western medicine group(integrated group),50 cases in each group.The Chinese medicine group was treated with Huangjing Xinshang Ointment,the western medicine group was treated with kinesio taping,and the integrated group was treated with the modified kinesio taping of integrated Chinese and western medicine,with a course of 14 days.The changes on the active range of motion(AROM) in knee and Western Ontario and McMaster Universities(WOMAC) osteoarthritis indexes were observed and compared.Results ①For the comparison of treatment before and after,there was statistically significant difference on the flexion angle in the Chinese medicine group (P＜0.05),and there were statistically significant differences on the angles of flexion,internal rotation and external rotation angle in the western medicine group and integrated group(P＜0.05).After treatment,the improvements on the angles of flexion,internal rotation and external rotation angle in the western medicine group and integrated group were obviously better than those in the Chinese medicine group (P＜ 0.05).While there were no statistically significant differences on the angles of flexion,internal rotation and external rotation angle between the western medicine group and integrated group (P＞0.05).②For the comparison of treatment before and after,there was statistically significant difference on the score of pain in all groups (P＜0.05),and there were statistically significant differences on the scores of stiffness and daily activity difficulty in the western medicine group and integrated group(P＜0.05),but there were no statistically significant differences on the scores of stiffness and daily activity difficulty in the Chinese medicine group(P＞0.05).After treatment,the scores of pain and daily activity difficulty in the integrated group were obviously lower than those in the western medicine group and Chinese medicine group(P＜0.05),the score of stiffness in the western medicine group and integrated group was obviously lower than that in the Chinese medicine group(P＜0.05),and there was no statistically significant difference on the score of stiffness between the western medicine group and integrated group(P＞0.05).Conclusion Modified kinesio taping of integrated Chinese and western medicine shows good efficacy in the treatment of knee osteoarthritis,which can obviously improve the active range of motion in knee joint of patients,and relieve the symptoms such as pain,stiffness and so on.

Diffuse intrinsic pontine glioma (DIPG) is the main cause of pediatric brain tumor death. This study was designed to identify key genes associated with DIPG.

膝关节疾病易发多见,贴扎技术作为主要的非侵入性治疗技术也已广泛应用于临床.结合各类膝关节受累疾病总结了近年贴扎相关的临床应用研究进展,为贴扎技术改善膝关节各类主诉尤其是运动功能障碍方面提供一定参考.

Summary of the effectiveness of different types of proprioception training on motor dysfunction caused by different diseases by analyzing a number of relevant literatures at home and abroad. Findings showed that motor dysfunction was the most common symptom in stroke, sports injury, musculoskeletal disease, lumbar vertebrae degeneration, dystonia, etc.. A large number of reports advocated that the above diseases all had the loss of proprioception. It was necessary to apply proprioceptive training. Proprioceptive training included active movement and balance training, passive movement training, somatosensory stimulation training, somatosensory discrimination training and multiple system training. Somatosensory stimulation training was effective in patients with motor dysfunction caused by central nerve injury. Passive movement training and balance training could effectively improve motor function of patients with sports injury; otherwise, the total effective rate of active movement training was relatively low. Whole body vibration of somatosensory stimulation training was the most effective form to improve motor dysfunction caused by dystonia in patients with Parkinson's disease. Proprioception training had got more and more attention on rehabilitation of patients with a variety of motor dysfunction.