The aim of this study was to investigate the effects of acupressure bladder meridian (ABM) on anxiety in rats. Chronic stress was induced rats to establish rat anxiety model. Shuttle experiment and open field experiments of were used to measure behaviors. The levels of cytokines in serum and hippocampus of rats were detected. Brain neurotransmitters (dopamine, 5- hydroxy tryptamine, norepinephrine) were detected by Enzyme linked immunosorbent assay (ELISA) kits. Immunohistochemistry and western blotting were used to detect MAPK and BDNF signal pathway in hippocampus of rats. ABM significantly improve behaviors, decreased cytokine levels in serum and hippocampus. ABM restored the changes of neurotransmitters and significantly decreased protein expressions of MAPK signal pathway and increased protein expressions of BDNF signal pathway in hippocampus of rats. The results shown that ABM significantly improved anxiety via inhibition of MAPK signal pathway and increased BDNF signal pathway.

The close relationship between pain and mental health problems is well-known, and psychological intervention can provide an effective alternative to medication-based pain relief. However, previous studies on the connection between pain and psychological problems, the findings thus far have been inconclusive, limiting the potential for translating psychological interventions into clinical practice. To complement the gap, this study utilized genetic data and Mendelian randomization (MR) to examine the potential relationship between pain in different parts and common mental disorders. Based on the instrumental variables selected from the Genome-wide association study summary statistics of localized pain and mental disorders, we conducted bidirectional two-sample MR analyses to infer bidirectional causal associations between pain and mental disorders. The inverse-variance weighted MR method and MR-Egger were used as the primary statistical method according to the horizontal pleiotropy and heterogeneity level. We reported the odds ratio to infer the causal effect between pain and mental disorders. F statistic was calculated to measure the statistical efficacy of the analyses. Insomnia is causally related to the genetic susceptibility of multisite pain including head (OR = 1.09, 95

The aim of this paper was to explore the mechanism of bladder meridian massage (BMM) on anxiety in rats with chronic stress. Chronic stress induced rats to establish rat anxiety model. The sugar water preference (SPF), tail suspension time (TST), and forced swimming time (FST) of rats were measured. The levels of superoxide dismutase (SOD), malondialdehyde (MDA), and inflammatory cytokines in serum and hippocampus of rats were detected. Brain neurotransmitters (dopamine (DA), 5- hydroxytryptamine (5-HT), and norepinephrine (NE)) were detected by enzyme-linked immunosorbent assay (ELISA) kits. Immunohistochemistry and western blotting were used to detect autophagy protein expression in hippocampus of rats. BMM significantly increased SPF, decreased TST and FST, increased SOD level in serum and hippocampus, and decreased MDA level and cytokine level. BMM reversed the changes of neurotransmitters. At the same time, BMM significantly decreased autophagy protein expression in hippocampus of rats. The above results show that BMM significantly relieve anxiety induced by chronic stress in rats.

目的 观察代谢方治疗代谢综合征糖脂代谢异常的临床疗效.方法 将88例代谢综合征糖脂代谢异常病人随机分为对照组和治疗组.对照组给予阿托伐他汀钙片、盐酸二甲双胍片治疗,治疗组在阿托伐他汀钙片、盐酸二甲双胍片基础上加用代谢方治疗.治疗3个月后,观察两组总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、餐后2h血糖、糖化血红蛋白、空腹胰岛素变化.结果 治疗后,对照组总有效率为72.7％,治疗组为95.5％,两组比较差异有统计学意义(P<0.05).治疗后,两组体质指数、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、胰岛素抵抗指数较治疗前降低,高密度脂蛋白胆固醇升高,且治疗组均优于对照组,差异有统计学意义(P<0.05).结论 在常规治疗基础上加用代谢方治疗代谢综合征在降脂、降糖方面有明显疗效.

焦虑症作为情志类疾病,符合脑不调神,肝失疏泄的病机特点.总体治疗思路当以调神为主,兼调脏腑.本文从焦虑症的病机特点,结合脏腑的生理病理特征,探讨"心""脑"与焦虑症的相关性.通过查阅相关文献总结临床推拿治疗本病取穴规律,进一步探讨推拿治疗焦虑症的取穴思路,以期为临床推拿治疗焦虑症选穴的合理化、标准化提供参考.推拿治疗时从"心脑同治,腹背双调"角度出发,以脏腑、经络等理论为依据,治"脑"取百会、风池、太阳、印堂、四神聪,调"心"取心俞、神门、内关;再者治"腹"取中脘、气海、关元,调"背"取肝俞、脾俞、胃俞、胆俞.这种推拿取穴思路相辅相成,发挥协同作用,达到心脑同治,腹背双调的效果,有助于较好地缓解焦虑症的各种症状.

Objective:A set of standardized Mini-CEX scoring standards with characteristics of traditional Chinese medicine is planned to be applied to the clinical practice assessment of medical students in our hospital, so as to improve the clinical practice and assessment efficiency.Methods:From January 2016 to December 2016, 40 students of 2012 five-year program of Shanghai University of Traditional Chinese Medicine majoring in Integrated Traditional Chinese and Western Medicine, who were interned in Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, were divided into standardized group and traditional group by random number table method, with 20 students in each group. The standardization group implements the standardized Mini-CEX assessment method, while the traditional group implements the traditional Mini-CEX assessment method. Statistical analysis of the two groups of students assessment results, and students and teachers of the questionnaire survey results were analyzed.Results:The Mini-CEX score of standardized group was lower than that of traditional group[(2.45±0.88)vs(4.65±0.67), P<0.01]. Compared with the traditional assessment method of mini CEX, teachers scored higher on standardized Mini-CEX in terms of "clear scoring basis" [(7.90 ± 0.56) vs (2.90 ± 1.37) , P<0.01]; students scored higher on standardized Mini-CEX in terms of "clearer teacher's comments" and "new experience in TCM consultation method" [(5.95±2.08)vs(1.50±0.60), (4.20±0.69)vs(2.15±1.26), all P<0.01]. Conclusions:The establishment of standardized Mini CEX scoring standards helps to ensure the fairness and preciseness of assessment and education and teaching, so as to improve the quality of teaching.

文章从教学内容、教学方法和教学用具三方面谈了作者的《小儿推拿学》教学体会,提出应改变重理论轻实践、重推拿轻儿科、重应用轻人才培养的现状,培养有“三心”(爱心、热心、耐心)和“三高”(高素质、高技术、高医德)的实用性小儿推拿医师.

目的:研究智能按摩椅对人体体表红外辐射温度的影响,探讨其对促进局部血液循环的作用.方法:招募志愿者20名.对符合纳入标准受试对象给予30min,模式为"休憩促眠"的按摩按摩程序.受试者每周接受2次按摩椅干预,持续4周.分别观察记录受试者干预前后腰骶、腹部、颈部等部位(穴位)的体表红外辐射温度的变化,并进行统计学处理与分析.结果:双侧人迎穴红外平均温度干预前分别为(32.46±0.48)?C、(32.50±0.50)?C,干预后为(33.78±0.38)?C、(33.81±0.39)?C,左右人迎穴干预前后红外温度变化均有显著性差异(P<0.05).关元穴干预前红外平均温度为(28.88±0.64)?C,干预后为(30.22±0.71)?C(P<0.05).八髎穴区域干预前红外平均温度为(28.07±0.53)?C,干预后为(29.07±0.56)?C,其红外温度干预前后的变化有显著性差异(P<0.05).结论:智能按摩程序能促进颈项部、腰骶部、少腹部血液循环.

Breast milk is recognized and strongly recommended by the World Health Organization (WHO) as the optimal feeding for all babies. Breastfeeding is associated with better nutritional and non-nutritional outcomes when compared to formula feeding, and has proven health benefits to both infants and their mothers. This clinical research is to examine the feasibility and efficacy of Acupoint-Tuina therapy in treating postpartum women who underwent C-sections and suffered from insufficient milk production. The patients in the control group received standard medical care, while the patients in the Tuina group received Tuina therapy during the next 48hours in addition to standard care, given once daily for 2 days. To evaluate the efficacy of Tuina therapy, patients of both groups were assessed for surface temperature of breasts, volume of breasts, volume of breast milk production, serum PRL level, and uterus recovery at various time points. Tuina therapy significantly increased the milk production when compared to the control group, for as much as 13-fold and 10-fold of that in the control group on the third and fourth postpartum days. In addition, Tuina therapy also significantly increased the full breast enlargement and the serum PRL level change, and decreased the breast surface temperature rise. Last but not the least, Tuina therapy also accelerated the post-surgery recovery of uterus. During the early postpartum days, Tuina therapy increases the milk production and promotes other physiological changes supporting lactation for postpartum women with C-section delivery and insufficient breast milk production. The novel intervention is warranted for further investigation and validation.

推拿功法少林内功是推拿学科教学主要功种之一.通过整理推拿功法少林内功的基本内容,从内功推拿流派公认的创始人李树嘉着手,对推拿功法少林内功的源流进行了稽考,否定了与少林武功的直接关系;从传承与功势特征等方面认为推拿功法少林内功与山东济宁李氏查拳有着密切的联系,并对比内功的历史文献,证明推拿功法少林内功属内功功法范畴.

目的:分析、探讨喘可治注射液联合小剂量布地奈德治疗老年支气管哮喘临床疗效以及对生活质量影响.方法:将178例老年支气管哮喘患者采用数字表法分为试验组与对照组.对照组常规使用布地奈德治疗,试验组使用喘可治注射液联合小剂量布地奈德治疗,对比两组在实施不同方案治疗后临床治疗疗效及生活质量情况.结果:试验组临床总有效率(82.02％)明显高于对照组(P<0.05);试验组躯体健康评分(77.88±5.91)及心理健康评分(74.97±2.91)均明显高于对照组(P<0.05);试验组PEF变化值、日均缓解药物使用次数均明显优于对照组(P<0.05).结论:对老年支气管哮喘予以喘可治注射液联合小剂量布地奈德进行治疗,在减少激素用量的情况下有较好的临床疗效,药物安全性好,能够有效缓解病患胸闷、喘息等不适症状,哮喘急性发作状况明显降低,肺功能得到改善,其生活质量也显著提高.

Shaolin Neigong (internal Qigong) of tuina exercise is a distinctive part of Neigong tuina. Since the 1980s, domestic basic study on Shaolin Neigong has mainly focused on its physiologic effects, and has preliminarily proved that Shaolin Neigong can enhance the aerobic capacity, cardio-pulmonary function, and muscle strength of human body. By summarizing the literatures studying the effects of Shaolin Neigong on respiratory, circulatory, locomotor and nervous systems, this article was to understand the modern research, inheritance and protection of Shaolin Neigong. The results indicate that the modern research on Shaolin Neigong is relatively slow. Continuous development, continuity and innovation in basic research, teaching and clinical practices are required, to enhance the general and therapeutic level of tuina exercises and tuina science of traditional Chinese medicine.

《素问?刺腰痛篇》是诸腰痛针刺法的专题文献，其中散脉腰痛可以概括为膝-腰疼痛关联涉及感觉异常和内脏器官功能障碍征象。基于推拿古代专著缺失，有感于不同理论指导下的选穴差异对临床疗效的重要影响，且针灸推拿均涉及取穴，为此，笔者现就散脉腰痛古代文献结合临床作一探讨。

目的:观察头针兴趣区推拿治疗失眠的临床疗效.方法:采用临床对照试验,将门诊失眠患者随机分为头针兴趣区推拿组和常规推拿组.连续治疗4个疗程后,以匹兹堡睡眠质量指数(PSQl)评分进行疗效评估,观察2组治疗前后PSQ1评分变化.结果:两组患者睡眠质量均有所提高;头针兴趣区推拿组患者PSQI总积分及睡眠质量、入睡时间、日间功能障碍的改善均优于对照组.结论:头针兴趣区推拿是治疗失眠的有效方法.

目的:观察经穴推拿为主治疗外吹乳痈初起的疗效.方法:采用自拟的“五步推拿法”对55例外吹乳痈初起患者进行推拿治疗.结果:推拿治疗后疼痛、结块及伴随的主要症状积分较治疗前都明显降低,前后分数差值有统计学意义(P＜0.001).推拿对疼痛的治疗有效率为85％,对结块和主症的治疗有效率均在91％以上.结论:“五步推拿法”能明显减少外吹乳痈初起患者的疼痛,改善或治愈患者的结块及相应的伴随症状,能提高母乳喂养成功率,降低产妇哺乳期乳腺炎的发生率.

To summarize the causes and influencing factors which are analyzed domestically and abroad.To comment the clinical researches of auricular-acupressure treating postpartum hypogalactia.The efficiency has been examined and supported by clinical trials.It is with great value in the field of post-natal care.This summary will lay foundation for future clinical research on auricular-acupressure treating postpartum hypogalactia.

Objective. To ascertain pathological information on hyperplasia of mammary glands (HMG) of patients via the infrared radiation temperature of acupoints. Method. Patients with HMG and healthy controls were tested using an infrared thermal imager. Results. In controls, no significant difference in temperature was observed between points with the same name (P > 0.05). The temperature of all tested points was found to be higher in the group with HMG than in that of the healthy controls, except for the left and right Zusanli (ST36). The temperature of the right Rugen (ST18), Guanyuan (CV4), Qihai (CV6), and Hegu (LI4) reached a statistically significant heightened level (P = 0.046~P < 0.001). The temperature of the Zusanli (ST36) and Hegu (LI4) present on the right side was significantly higher than that of the left (P = 0.001 and P = 0.004, resp.), while the temperature of the left Youmen (KI21) was significantly higher than that of the right (P = 0.008). Conclusion. The temperature of the bilateral acupoints in healthy controls was symmetrical, and the raised temperatures observed of the Rugen (ST18), Guanyuan (CV4), Qihai (CV6), and Hegu (LI4) acupoints of HMG patients and the imbalance of the temperature of the bilateral acupoints Zusanli (ST36), Youmen (KI21), and Hegu (LI4) carried special pathological information about HMG disease.

[目的]观察剖宫产术后实施早期乳房推拿对乳汁分泌的影响.[方法]将71例剖宫产病人按床号的不同分为观察组35例和对照组36例.观察组在常规护理早吸吮、按需哺乳等基础上,从术后24 h起对产妇进行乳房推拿疗法(每次10 min～15 min,每天3次或4次,连续2d),对照组在常规护理早吸吮、按需哺乳等基础上,从48 h起即乳房充盈胀痛时对产妇进行乳房推拿疗法(每次10 min～15 min,每天3次或4次,连续2d),比较两组推拿前及推拿48 h后乳房胀痛发生率、血清泌乳素、乳房体积及始乳时间的变化.[结果]观察组乳房胀痛发生率明显低于对照组(P＜0.05),血清泌乳素水平明显高于对照组(P＜0.01),始乳时间早于对照组(P＜0.01),乳房体积大于对照组(P＜0.01).[结论]剖宫产术后实施早期乳房推拿疗法,可有效防治乳房胀痛,促进泌乳.

"头痛医脚"是中国传统医学独具特色的诊疗思路与治疗方法。刺激足底涌泉穴治疗巅顶头痛的方法极具代表性。笔者认为,"头痛医脚"的机理可能与中医经络理论、脏腑理论以及现代医学的血管、神经反射学说、全息理论等有密切联系。

Objective To observe the clinical efficacy for atrophic senile macular degenertation(consumption of liver and kidney pattern,deficiency of qi and blood pattern)by softening liver to fortify spleen and nourishing yin to improve eyesight methods.Methods Sixty cases were randomized into two groups: treatment group in which 30 cases(60 eyes) were treated by Chinese medicine with liver-softening spleen-fortify and yin-nourishing eyesight improvement effects,and control group in which 30 cases(60 eyes) were treated by "Qiju Dihuang Pill" combined "Xiaoyao Pill",with the course of 3 months.The main symptoms,distant vision,central scotoma were detected,and the clinical efficacy was evaluated.Results The overall effective rate was 73.3% in the treatment group and 46.7% in the control group;there was significant difference in clinical efficacy between the two groups(P<0.05).In treatment group,there were significant differences in distribution of central scotoma,distant vision and scores of blurred vision,dry eyes,dizziness,tinnitus and weak waist between before and after treatment(P<0.05);in control group,there were significant differences in blurred vision,dry eyes,dizziness,tinnitus and weak waist between before and after treatment(P<0.05);after treatment,there were significant differences in distribution of central scotoma,distant vision and scores of blurred vision,dry eyes,dizziness,tinnitus and weak waist between the two groups(P<0.05).Conclusion Softening liver to fortify spleen and nourishing yin to improve eyesight methods can improve the central vision,distribution of central scotoma and clinical efficacy in patients with senile macular degenertation of consumption of liver and kidney pattern and deficiency of qi and blood pattern.