目的:探究护理干预模式应用于地中海贫血孕产妇的临床效果.方法:研究对象全部选择2017年1月-2018年4月在本院进行产检直到本科分娩的236例地中海贫血产妇,按照不同护理干预方式分成两组,即干预组(n-118)和常规组(n=118).常规组患者开展普通孕期护理,基于此干预组则开展护理干预模式,将临床效果进行分析对比.结果:两组剖宫产、重型地中海贫血患儿、母乳喂养、产后一周情绪低落、伤口愈合不良及护理满意度比较,差异均有统计学意义(P＜0.05).结论:护理干预模式用于地中海贫血孕产妇临床效果较好,有助于降低剖宫产率,提高人口素质,促进护理满意度提升.

目的 探讨应用同位素标记相对和绝对定量技术(iTRAQ)筛选的相关差异蛋白在重症肺炎患儿并心肌损害和心力衰竭诊断中的临床价值,为临床诊治提供参考依据.方法 通过强阳离子交换色谱分析法的8种不同同位素标记的iTRAQ和液相色谱法以及串联质谱分析重症肺炎患儿(观察组)和健康儿童(对照组)血清蛋白.通过Mascot软件分析和GO分析表达差异的蛋白.结果 与对照组相比,观察组中共鉴定出有定量信息的蛋白质89个,包括61个上调蛋白和28个下调蛋白.生物信息学分析显示差异表达的蛋白主要参与急性期反应、氧运输活动及酶催化等过程,这些表达差异的蛋白中选择5个显著表达差异作为候选蛋白,分别是CRP、SAA、PI16、BLVRB、G3P.结论 本研究发现这5种蛋白在小儿重症肺炎并发心肌损害和心力衰竭过程中发挥重要作用,可能作为该病潜在的临床筛查生物标志物.

目的 探究预见性护理对产妇阴道分娩后出血情况的影响.方法 自我院2017年1月—2018年8月产检的孕妇中选取212例作为本次研究对象,将其按照产检前后顺序分为两组,每组106例,对照组实施常规护理,研究组实施预见性护理,对比两组产妇生产后2 h、12 h、24 h出血情况以及产妇对护理工作的满意度.结果 研究组产妇生产后2 h、12 h、24 h阴道出血量均少于对照组,且对护理工作的满意度高于对照组,各组间差异有统计学意义(P<0.05).结论 产妇围生期实施预见性护理能够有效降低阴道分娩产妇产后阴道出血量,保障产妇身心健康,提高医疗质量,提高产妇对护理人员的满意度,减少医疗纠纷.

目的 探究妊娠期高血压疾病患者采取综合性护理干预的效果及对患者生活质量产生的影响.方法 选取我院2017年6月—2018年12月收治的98例妊娠期高血压患者作为研究对象.应用随机数字表的方式,将其平均分为实验组与对照组.两组患者分别采取综合护理干预及常规护理干预方式对患者进行干预,判别护理效果.结果 经研究,实验组的不良妊娠结局发生率低于对照组,实验组患者的生活质量主要包括生理功能、心理功能、社会功能和躯体功能均优于对照组,差异均具有统计学意义(P<0.05).结论 采用综合性护理干预措施对妊娠期高血压疾病患者进行干预,能够提高患者的生活质量,减少不良妊娠结局的出现.

Objective:Using isobaric tags for relative and absolute quantification (iTRAQ) technology to analyze the proteins in serum of β-thalassaemias and find the differentially expressed proteome.Methods:Analyzing the total proteins in serum samples from patients with β-thalassaemias and samples of healthy controls by using eight-plex iTRAQ added with strong cation exchange choematography and liquid chromatography coupled with tandem mass spectrometry.The differentially expressed proteins were identified by Mascot and GO.Results:A total of 58 differentially expressed proteins were identified,including 49 proteins were up-regulation and 9 proteins were down-regulation.Bioinformatics analysis revealed that differential expression proteins were mainly related to the blood coagulation Coagulation,hemostasis,wound healing,response to wounding,regulation of body fluid levels,acute inflammatory response,vesicle-mediated transport,platelet activation,and platelet degranulation process.Among of them,there were 5 proteins significant differentially expressed,including CRP,SAA1,HBA,FBLN1,and HRG.Conclusion:This study found that 5 kinds of protein in children with mycoplasma pneumonia play an important role in the process,promisingly as the disease clinical screening of potential biomarkers.

目的:筛选卵巢过度刺激综合征的血清生物标记物.方法:选择临床明确诊断的卵巢过度刺激综合征患者(观察组)以及健康妇女(对照组)各20例,利用同位素标记相对和绝对定量(iTRAQ)技术检测其血清差异蛋白,并进行功能注释及生物信息分析,筛选出差异明显的候选蛋白.结果:与对照组相比,观察组获得64种血清差异蛋白.参与的主要生物学过程为炎症反应和免疫应答等,并获得与疾病相关的标志物5个.结论:炎症和免疫功能改变可能在该病证发生发展中发挥着关键性作用,5种蛋白可能作为卵巢过度刺激综合征的血清候选差异蛋白.

Objective:To discuss the effect of getting out of bed assisted by X ray film in the puerpera with cesarean section. Methods:Ma-ternal pain degree and anxiety level before and after using X ray film were evaluated and compared by visual analogue scale and Zung self-rating anxiety scale. Results:Maternal pain degree and anxiety were less after using X ray film, and differences were of statistical significance( P <0. 05). Conclusion:The application of X ray film in assisting the puerpera with cesarean section out of bed can reduce pain and anxiety, and improve maternal satisfaction. It is worthy of clinical application.

目的：方便护士的临床工作，提高工作效率，杜绝污染，减少药物的浪费。方法：50名实习4个月以上的实习生分别使用输液管调节器的缠绕法、输液管调节器的滑动法、用手的缠绕法、用笔的缠绕法。结果：使用输液管调节器缠绕法所用的时间较短，成功率高，舒适度好。结论：使用输液管调节器的缠绕法简单易学，取材方便，可杜绝污染，提高护士的工作效率，值得临床推广应用。

Objective: To observe the effect of low-frequency pulse therapy instrument on postpartum uterine involution, early maternal lactation, milk secretion, and postpartum urinary retention. Methods: randomly selected 200 cases of test group and control group respectively, between October 2010 and February 2011, application of low-frequency pulse therapy instrument daily for 2 times,6 days of continuous treatment for the test group; Traditional food and pharmaceutical care for the control group. Comparing the accident of lactation, urinary retention and involution of uterus between two groups. Results: Increasing milk secretion and reducing the accident of breast stasis, rinary retention, postoperative intestinal flatulence and 24 hours postpartum hemorrhage volume, improving involution of uterus were proved in the test group. Conclusion: Low-frequency pulse therapy instrument improve postpartum recovery, safe and reliable, easy to use, affordable, and less adverse reaction, is worth popularization and application in obstetric ward.

目的:分析畸胎死胎引产产妇心理问题,探讨减轻心理问题的方法。方法:对畸胎死胎引产产妇100例采用Zung焦虑自评量表(SAS)和抑郁自评量表(SDS)在入院后24 h内进行心理自评,根据测评问题施行针对性的心理哀伤辅导,出院前再测评1次心理状态,比较哀伤辅导前后患者心理差异。结果:施行心理哀伤辅导措施后患者的心理状态明显好转,与实施前比较差异有统计学意义(P<0.01)。结论:畸胎死胎引产产妇大多有不同程度的心理问题,通过哀伤辅导,能明显地减轻焦虑症状。

目的探讨孕晚期死胎引产产妇哀伤情绪的心理干预方法。方法选取由于孕晚期死胎而住院引产,且经周产期哀伤量表测试出具有哀伤情绪,经三维筛选评估模型评估需要指导性干预的产妇32例,在引产前后对其语言、行为、认知等进行干预,对比干预前后焦虑、抑郁的得分差异,对护理满意度评价结果的差异。结果干预后,本组产妇哀伤情绪、焦虑、抑郁程度有明显改善(P<0.05),护理满意度提高(P<0.05)。结论语言、行为、认知等护理干预能明显减轻引产产妇哀伤情绪,提高其对护理服务的满意度。

Objective To explore the value of hemabate on breast-feeding success rate of parturient treated by hemabate.Methods 250 cases with intrapartum,postpartum hemorrhage were divided into two groups:treatment group(125 cases) was treated with hemabate and traditional therapy;control group(125 cases) with traditional therapy only.Results There were significant differences of postpartum serum PRL values between two groups,and there were significant differences of the milk secretion and breast-feeding success rates between two groups too.Conclusion Hemabate can avoid intrapartum and postpartum hemorrhage,reduce puerperal complications,especially the uterus resection rate,with no negative effect on parturient

目的评价健康教育在母乳喂养中的作用。方法把孕母分为实验组和对照组,对实验组开展母乳喂养方面的健康教育,并与对照组进行比较,采用χ2检验评价健康教育的效果。结果实验组与对照组孕妇母乳喂养的知识、态度的差别有统计学意义,且实验组的母乳喂养率较对照组高(χ2=17.45,P<0·01)。结论健康教育对提高孕妇母乳喂养知识水平,树立正确母乳喂养观有积极意义。