Rattus tanezumi (R. tanezumi) is a major amplifying host for plague and an important reservoir host for multiple zoonotic pathogens, including leptospirosis and hantavirus. Its population dynamics in the Three Gorges Reservoir (TGR) Area of China are influenced by climate and reservoir-induced environmental changes, thereby impacting disease transmission risks. Based on rodent capture rate data collected using cage traps during night surveys in January, March, May, July, September, and November each year from 2015 to 2021, this study investigated the spatiotemporal dynamics of R. tanezumi and its association with key meteorological and environmental factors. Using Geographic Information Systems (GIS) for spatiotemporal analysis and a Generalized Additive Model (GAM), we identified the current month’s average temperature and relative humidity, together with 3-month-lagged precipitation and the Normalized Difference Vegetation Index (NDVI), as associated factors. The highest capture rate occurring at around 20 °C. Rat capture rate negatively correlated with both current relative humidity and lagged precipitation and a fluctuating decline with increasing lagged NDVI. This study demonstrates how climatic and environmental factors shape the spatiotemporal distribution of R. tanezumi population in the Three Gorges Reservoir Area. These findings provide insights that may inform predictions of rodent‑borne disease risks and support the development of targeted surveillance and control strategies in this ecologically vulnerable region.

To assess the impact of implementing a two-dose varicella vaccine (VarV) immunization recommendation program on the incidence of varicella in Chongqing, China. Monthly reported varicella cases from 2011 to 2023 were extracted from the National Notifiable Diseases Reporting System (NNDRS), alongside the vaccination records from the Chongqing Immunization Planning Information Management System. The interrupted time series analysis (ITS) was employed to study the epidemiological trends of varicella. The average reported annual incidence of varicella in Chongqing was 69.6 per 100,000 population during 2011-2023, with the highest incidence recorded in 2019 (133.9 per 100,000 population) and the lowest in 2011 (21.3 per 100,000 population). Children aged 5-9 y accounted for 34.5% of the total cases. Second-dose coverage of VarV surged from 4.1% in 2018 to 27.5% in 2023 among children aged 4-6 y. The segmented regression model demonstrated that, following the incorporation of varicella into the surveillance system in 2014, there was an upward long-term trend in the reported varicella incidence (β3 = 0.118, P < .01). Following the implementation of the two-dose VarV recommendation strategy in January 2019, a significant long-term decline trend was observed (β5 = -0.209, P < .01). The official inclusion of varicella into the notifiable disease surveillance can improve the detection, reporting, and evaluation of varicella cases in real-world settings. The implementation of a two-dose VarV recommendation strategy, along with increased coverage of the second dose, can effectively reduce the varicella incidence. Maintaining sensitive surveillance and adhering to the two-dose vaccination schedule are crucial for controlling varicella epidemics.

To characterize the epidemiological profile, population seroprotection levels, and economic impact of varicella in Chongqing, and to provide evidence to optimize immunization strategies to reduce incidence and economic burden. The epidemiological trends of varicella in Chongqing were ascertained from routine surveillance data (2011–2024). Population sero-epidemiology was evaluated using a randomized cross-sectional serosurvey (n = 960, 2024), and economic burden was estimated from 14,779 outpatient and 298 inpatient cases (2019–2022). Statistical analyses (descriptive statistics, Chi-squared test, Kruskal-Wallis test, and Wilcoxon rank-sum test) were conducted to quantify incidence trends, factors associated with antibody levels, and heterogeneity in economic burden. A total of 301,714 cases were reported during 2011–2024, with 53.56

Entomopathogenic microorganisms, including bacteria, fungi, and viruses, present a promising approach to mosquito control due to their high efficacy, species specificity, and environmental safety. Targeting larval stages is a strategic component of integrated mosquito management, leveraging the accessibility and concentration of immature mosquitoes in aquatic habitats. This review comprehensively examines diverse entomopathogenic larvicides, encompassing their larvicidal molecules, biochemical mechanisms of action, current application strategies, and prevailing challenges. Bacterial agents, notably Bacillus thuringiensis var. israelensis (Bti) and Lysinibacillus sphaericus (Lbs), remain the most widely deployed. Entomopathogenic fungi and viral pathogens demonstrate potent larvicidal activity, highlighting their significant potential for the development of novel bio-larvicides. Innovative formulation strategies and synergistic combinations of microorganisms with chemical pesticides offer promising avenues for efficacy enhancement. Concurrently, the ongoing isolation and characterization of novel larvicidal microorganisms are crucial for expanding the repertoire of biological control agents. These approaches enhance long-term control sustainability by mitigating resistance development. While challenges persist for large-scale implementation, entomopathogenic microorganisms present a compelling and sustainable pathway for effective mosquito management.

BACKGROUND:Mosquitoes are major vectors of disease and pose a significant threat to public health. Chemical insecticides face resistance and environmental issues, prompting the need for eco-friendly alternatives such as entomopathogenic fungi. However, their potential across mosquito life stages remains underexplored. As a primary malaria vector in East Asia, Anopheles sinensis remains understudied in terms of biological control approaches. RESULTS:Four effective fungal strains were initially screened from 22 fungal isolates based on their pathogenicity against An. sinensis larvae. Among them, strain Metarhizium anisopliae (Ma)421 demonstrated the best overall performance when further assessed for its mosquito-killing activity at the egg, pupa and adult stages, as well as its sporulation capacity on mosquito cadavers. Fungal infection reduced hatching rates, impaired larval pupation and adult emergence, and caused morphological deformities in newly emerged adults-such as malformed wings and legs-ultimately leading to mortality. Further analysis of Ma421 revealed a significant suppression of blood-feeding behavior, reduced egg-laying, and lower hatching, pupation and adult emergence rates in the next generation. These findings indicated that Ma421 induced transgenerational effects by decreasing reproductive success in subsequent generation, which is an important finding with promising implications for sustainable mosquito control. CONCLUSION:This study fills a significant gap in the fungal-based biological control of An. sinensis, with the multistage efficacy of Ma421 highlighting its potential for use in integrated vector management. Its transgenerational impact further underscores its potential as an eco-friendly alternative to chemical insecticides, supporting its incorporation into sustainable mosquito management strategies. © 2025 Society of Chemical Industry.

OBJECTIVES:To evaluate the impact of China's two-dose measles-mumps-rubella (MMR) vaccination strategy on mumps incidence using interrupted time series (ITS) analysis in a megacity of China from 2004 to 2024. METHODS:Monthly reported mumps case data were extracted from China's National Mandatory Disease Reporting System (NNDRS). Segmented regression models assessed policy effects across three periods: pre-vaccine during 2004-2007, one-dose MMR during 2008 to 2020, and two-dose MMR during 2020-2024. The Newey-West correction is used to address autocorrelation issue (P < 0.01 for Durbin-Watson test). RESULTS:Adolescents aged 10-15 years have the highest reported mumps cases across all the years, but with lower case peaks since the two-dose MMR schedule in 2020. ITS analysis revealed a significant downward trend after the two-dose MMR vaccination schedule with a slope change of -0.007 (P < 0.01) and an immediate reduction in cases with a level change of -0.256 (P = 0.056) on log-transformed value. The two-dose MMR policy generated a cumulative effect of reducing 53.76 % mumps morbidity on December 2024 compared to the one-dose policy. Age-specific incidence peaks have been shifted, with adolescents aged 10-15 years remaining to be highest-risk despite vaccination, and breakthrough infections persisted in highly vaccinated school populations. CONCLUSIONS:The two-dose MMR strategy significantly reduced mumps incidence in the city, supporting its effectiveness for epidemic control. However, persistent cases in adolescents propose consideration of school-based booster programs and enhanced surveillance for emerging strains.

Rattus tanezumi ( R. tanezumi ), a major vector for plague, leptospirosis, and hantavirus, exhibits population dynamics in the Three Gorges Reservoir (TGR) Area of China that are influenced by climate and reservoir-induced environmental changes, thereby impacting disease transmission risks. This study investigated the spatiotemporal dynamics of R. tanezumi and its association with key meteorological and environmental factors from 2015 to 2021. Using Geographic Information Systems (GIS) for spatiotemporal analysis and a Generalized Additive Model (GAM), we identified the current month's average temperature and relative humidity, together with three-month-lagged precipitation and the Normalized Difference Vegetation Index (NDVI), as significant drivers. The relationship was modeled (Yi,t = α + s 1 (M0Avg_Temp) + s 2 (M0Avg_RHU) + s 3 (M3Precip) + s 4 (M3NDVI) + ε; R²= 0.12, Deviance explained = 14%, GCV = 0.4438), revealing an optimal proliferation temperature around 20°C. Density showed negative correlations with both current relative humidity and lagged precipitation, and a fluctuating decline with increasing lagged NDVI. As the first investigation of its kind, this study demonstrates how climatic and environmental factors shape the spatiotemporal distribution of R. tanezumi in the TGR Area, providing critical insights for predicting outbreaks and formulating targeted surveillance and control strategies against rodent-borne diseases in this vulnerable region.

Dengue fever is a viral illness, mainly transmitted by Aedes aegypti and Aedes albopictus. With climate change and urbanisation, more urbanised areas are becoming suitable for the survival and reproduction of dengue vector, consequently are becoming suitable for dengue transmission in China. Chongqing, a metropolis in southwestern China, has recently been hit by imported and local dengue fever, experiencing its first local outbreak in 2019. However, the genetic evolution dynamics of dengue viruses and the spatiotemporal patterns of imported and local dengue cases have not yet been elucidated. Hence, this study implemented phylogenetic analyses using genomic data of dengue viruses in 2019 and 2023 and a spatiotemporal analysis of dengue cases collected from 2013 to 2022. We sequenced a total of 15 nucleotide sequences of E genes. The dengue viruses formed separate clusters and were genetically related to those from Guangdong Province, China, and countries in Southeast Asia, including Laos, Thailand, Myanmar and Cambodia. Chongqing experienced a dengue outbreak in 2019 when 168 imported and 1,243 local cases were reported, mainly in September and October. Few cases were reported in 2013-2018, and only six were imported from 2020 to 2022 due to the COVID-19 lockdowns. Our findings suggest that dengue prevention in Chongqing should focus on domestic and overseas population mobility, especially in the Yubei and Wanzhou districts, where airports and railway stations are located, and the period between August and October when dengue outbreaks occur in endemic regions. Moreover, continuous vector monitoring should be implemented, especially during August-October, which would be useful for controlling the Aedes mosquitoes. This study is significant for defining Chongqing's appropriate dengue prevention and control strategies.

The coffee berry borer, Hypothenemus hampei (Ferrari) (Coleoptera: Curculionidae), is a major destructive insect pest of coffee, which impacts the coffee crops negatively. As a draft genome has been completed for this insect, most molecular studies on gene transcriptional levels under different experimental conditions will be conducted using real-time reverse-transcription quantitative polymerase chain reactions (RT-qPCR). However, the lack of suitable internal reference genes will affect the accuracy of RT-qPCR results. In this study, the expression stability of nine candidate reference genes was evaluated under different developmental stages, temperature stress, and Beauveria bassiana infection. Data analyses were completed by four commonly used programs, BestKeeper, NormFinder, geNorm, and RefFinder. The result showed that RPL3 and EF1 alpha combination were recommended as the most stable reference genes for developmental stages. EF1 alpha and RPS3a combination were the top two stable reference genes for B. bassiana infection. RPS3a and RPL3 combination performed as the optimal reference genes both in temperature stress and all samples. Our results should provide a good foundation for the expression profile analyses of target genes in the future, especially for molecular studies on insect genetic development, temperature adaptability, and immune mechanism to entomogenous fungi in H. hampei.

目的 分析三峡库区重庆段小型兽类(小兽)及体表媒介蚤监测结果,为相关鼠源疾病防控提供基础资料和科学依据.方法 收集整理2019-2021年三峡库区重庆段小兽及其体表媒介蚤监测资料,分析小兽物种构成和密度变化以及小兽染蚤率、蚤指数等.利用SPSS 25.0软件进行x2检验对数据做统计分析.结果 2019-2021年间三峡库区重庆段监测发现小兽共10种2 860只,平均小兽密度为1.67％.其中居住区密度为2.74％,小兽密度呈现逐年下降趋势(x2=22.493,P＜0.001),优势兽种为黄胸鼠、褐家鼠和小家鼠;耕作地密度为0.60％,小兽密度在较低水平波动,各年小兽密度差异有统计学意义(x2=41.953,P＜0.001),以黄胸鼠、四川短尾鼩、小泡巨鼠为主;居住区与耕作地小兽构成比差异有统计学意义(x2=1 003.754,P＜0.001).小兽染蚤率为18.67％,总蚤指数为0.70,缓慢细蚤为优势蚤种.鼠疫血清抗体检测均为阴性.结论 2019-2021年三峡库区重庆段小兽种群及密度与成库时相比均发生了明显变化,黄胸鼠为优势鼠种,室内黄胸鼠密度远高于国家鼠疫控制标准,蚤种有缓慢细蚤和印鼠客蚤,应高度关注,加强鼠疫监测和及时开展灭鼠灭蚤工作.

[目的]探明黄翅绢丝野螟Glyphodes caesalis的求偶及交配行为节律,为该虫性信息素提取鉴定、两性通讯机制和群集诱杀技术研究提供理论基础.[方法]统计黄翅绢丝野螟的雌、雄蛹性比,测定成虫在光期和暗期的羽化率,观察其求偶和交配行为;利用等比配对试验测定寄主(菠萝蜜)、成虫日龄和暗期时段对交配率、交配时长和交配次数的影响.[结果]黄翅绢丝野螟雌、雄蛹平均性比为1.06:1,雌蛹占比显著大于雄蛹占比.黄翅绢丝野螟成虫羽化高峰期集中于光暗转换期的前、后2 h,交配仅发生于暗期,寄主(菠萝蜜)的存在对该虫交配有促进作用,有果组交配率为93.33％±2.89％,显著高于无果组(71.67％士14.43％);有果组和无果组交配日龄分别为3-5日龄和3-7日龄;有果组3日龄成虫的交配率为53.33％±11.55％,显著高于无果组(31.67％± 5.77％),两组交配率随日龄增加逐渐降低.有果组交配时段主要集中在进入暗期的0-2 h,其中暗期0-0.5 h为交配高峰期,较无果组提前,交配率为36.67％±17.56％;无果组交配时段主要集中在暗期的0-3.5 h,其中暗期1.0-1.5 h为交配高峰期,交配率为16.67％±11.55％.黄翅绢丝野螟雌成虫最多交配2次,雄成虫最多交配4次,但雌、雄成虫的交配比例随交配次数增加而递减;首次交配时间越早其多次交配概率越高,首次交配发生于3日龄的雌、雄成虫分别可进行2次和4次交配,首次交配发生于5日龄后的雌、雄成虫均无多次交配行为.[结论]黄翅绢丝野螟可进行多次交配,寄主菠萝蜜对其交配有促进作用,该虫交配行为具节律性,仅在暗期发生交配,交配高峰期为3-4日龄、大多发生在暗期的0-2 h内.

目的 监测重庆市重点地区小型兽类携带5种常见鼠媒病原体的流行情况,为指导当地鼠源疾病的防控提供科学依据.方法 2021-2022年,在重庆市中心城区、万州区、涪陵区3个监测点使用笼夜法捕捉小型兽类,提取其肝、脾、肺、肾组织的核酸样本,采用实时荧光定量PCR(qPCR)检测问号钩端螺旋体(钩体)、莫氏立克次体、巴尔通体,反转录实时荧光定量PCR(RT-qPCR)方法检测汉坦病毒及大别班达病毒.运用Excel 2010软件进行数据汇总和整理,SPSS 22.0软件对实验数据进行统计分析,种群构成比、病原体携带率的比较采用x2检验进行统计分析.结果 共捕获小型兽类9种1 188只,其中褐家鼠最多,占比为33.50％,黄胸鼠占比为26.77％,四川短尾鼩占比26.01％,小家鼠占比为9.85％,其余还捕获小泡巨鼠、大足鼠、北社鼠、黑线姬鼠、灰麝鼩,不同监测点的小型兽类种类构成差异有统计学意义(x2=714.786,P＜0.001).所有检测样本中,发现汉城型汉坦病毒阳性4份(只),问号钩体阳性24份(只),巴尔通体阳性8份(只),其余均为阴性.共发现33只小型兽类呈阳性,其中2只黄胸鼠、1只褐家鼠同时携带问号钩体和汉城型汉坦病毒,病原体总体携带率为2.78％,其中汉坦病毒总携带率为0.34％,问号钩体总携带率为2.02％,巴尔通体总携带率为0.67％,3种病原体的携带率差异有统计学意义(x2=18.857,P＜0.001).结论 重庆地区小型兽类中监测到问号钩体、巴尔通体和汉坦病毒,检出阳性较多的小型兽类为褐家鼠、黄胸鼠和四川短尾鼩,主要分布于重庆城区的重点行业和万州区的农村居民区,当地应对鼠源疾病流行及防控予以重点关注.

目的了解重庆市2019年登革热暴发疫情控制后白纹伊蚊对常用卫生杀虫剂敏感性状况,为预防登革热等蚊传疾病和指导媒介伊蚊用药提供依据。方法 2020年5-10月,选择重庆市6个区（县）的公园或废旧轮胎堆放处采集白纹伊蚊,带回实验室饲养1～2代,采用幼虫浸渍法及成蚊接触筒法开展抗药性监测。结果重庆市各调查点白纹伊蚊幼蚊对常用杀虫剂的敏感性均不同,抗性倍数在0.46～7.32倍。其中对双硫磷的抗性倍数为0.46～4.92倍,对残杀威的抗性倍数为0.82～7.32倍。重庆市各调查点白纹伊蚊成蚊对溴氰菊酯、氯菊酯、高效氯氰菊酯、高效氯氟氰菊酯均产生不同程度的抗性,24 h死亡率在5.88%～78.22%。除万州区野外白纹伊蚊成蚊对虫威和杀螟硫磷产生可疑抗性及大足区野外白纹伊蚊成蚊对毒死蜱产生可疑抗性外,其余调查点野外白纹伊蚊成蚊对残杀威、（口恶）虫威、马拉硫磷、杀螟硫磷、毒死蜱均为敏感。结论重庆市各调查点白纹伊蚊成蚊对拟除虫菊酯类药物均产生抗性,部分调查点白纹伊蚊幼蚊对双硫磷和残杀威产生低抗。建议定期监测白纹伊蚊的抗性水平及变化趋势,根据不同虫态的抗药性采取相应的杀虫剂使用策略。

过敏性疾病的发病率呈逐年上升趋势,受到社会公众、医务与环境工作者的广泛关注。环境因素是过敏性疾病发病与发展过程中极其重要的因素,研究表明室内过敏原如尘螨、真菌、花粉等可引发和加剧过敏个体的过敏症状如哮喘等,室内环境过敏原检测可以评估室内环境中过敏原含量,进一步提供干预措施,为个体化防治过敏性疾病提供重要依据。尘螨、真菌、花粉检测方法有很多,但室内环境中过敏原检测与处理的方法及相关标准尚无推荐,都亟待规范。本共识以室内环境过敏原（尘螨、真菌、花粉）检测相关的常见问题为导向,查阅相关文献,整合多学科专家意见,达成共识,形成室内环境中尘螨、真菌、花粉相关检测及处理方法的共识与建议。

Background Dengue fever has been a significant public health challenge in China. This will be particularly important in the context of global warming, frequent international travels, and urbanization with increasing city size and population movement. In order to design relevant prevention and control strategies and allocate health resources reasonably, this study evaluated the economic burden of dengue fever in China in 2019. Methods The economic burden of dengue fever patients was calculated from both family and the organisation perspectives. A survey was conducted among 1,027 dengue fever patients in Zhejiang, Chongqing, and Yunnan Provinces. Treatment expenses, lost working days, and insurance reimbursement expenses information were collected to estimate the total economic burden of dengue fever patients in 2019. The expenditures related to dengue fever prevention and control from government, Center for Disease Control and Prevention (CDC), communities and subdistrict offices of 30 counties (or districts) in Zhejiang Province and Chongqing City were also collected. Results The direct, indirect and total economic burden for dengue fever patients in 2019 in the three Provinces were about 36,927,380.00 Chinese Yuan (CNY), 10,579,572.00 CNY and 46,805,064.00 CNY, respectively. The costs for prevention and control of dengue fever for the counties (or districts) without cases, counties (or districts) with imported cases, and counties (or districts) with local cases are 205,800.00 CNY, 731,180.00 CNY and 6,934,378.00 CNY, respectively. The total investment of dengue fever prevention and control in the 30 counties in China in 2019 was approximately 3,166,660,240.00 CNY. Conclusion The economic burden of dengue fever patients is relatively high, and medical insurance coverage should be increased to lighten patients’ direct medical economic burden. At the same time, the results suggests that China should increase funding for primary health service institutions to prevent dengue fever transmission.

Japanese encephalitis (JE) is an acute infectious disease caused by the Japanese encephalitis virus (JEV) and is transmitted by mosquitoes. Meteorological conditions are known to play a pivotal role in the spread of JEV. In this study, a zero-inflated generalised additive model and a long short-term memory model were used to assess the relationship between the meteorological factors and population density of Culex tritaeniorhynchus as well as the incidence of JE and to predict the prevalence dynamics of JE, respectively. The incidence of JE in the previous month, the mean air temperature and the average of relative humidity had positive effects on the outbreak risk and intensity. Meanwhile, the density of all mosquito species in livestock sheds (DMSL) only affected the outbreak risk. Moreover, the region-specific prediction model of JE was developed in Chongqing by used the Long Short-Term Memory Neural Network. Our study contributes to a better understanding of the JE dynamics and helps the local government establish precise prevention and control measures.

目的收集和分析重庆市2020年登革热媒介伊蚊监测资料,为重庆市防控媒介伊蚊传播的疾病提供依据。方法选择2019年重庆市登革热出现本地疫情的万州区、渝北区和沙坪坝区以及未出现本地病例的黔江区、大足区和垫江县为调查点。采用布雷图指数法和诱蚊诱卵器法监测伊蚊幼虫,采用双层叠帐法监测伊蚊成蚊。利用Excel 2010软件对重庆市6个调查点媒介伊蚊监测结果进行分析,对登革热进行初步的风险评估。结果重庆市2020年4—12月平均布雷图指数（BI）为4.50,全市6—9月平均BI＞5,存在登革热传播风险。其中沙坪坝区6月,渝北区6—7月,万州区7—8月平均BI＞10,存在登革热暴发风险;平均诱蚊诱卵指数（MOI）为2.15,渝北区7月和8月平均MOI＞10,存在登革热暴发风险;平均媒介伊蚊成蚊密度为0.86只/（顶·h）。沙坪坝区和垫江县伊蚊密度帐诱指数较高,分别为1.81只/（顶·h）和1.48只/（顶·h）,其次为万州区1.04只/（顶·h）,沙坪坝区6—9月,万州区6—7月,垫江县5—6月及8—9月媒介伊蚊成蚊密度均＞2只/（顶·h）。结论 2020年重庆市不同区县,不同月份登革热媒介伊蚊传播疾病风险不同,渝北区、沙坪坝区和万州区相对风险较高。建议各区县持续加强媒介伊蚊监测和风险评估,为重庆市蚊传疾病的科学防控提供依据。

目的 测试金龟子绿僵菌CQMa421饵剂室内和现场防治德国小蠊效果,为真菌杀虫剂在防治卫生害虫上的应用提供参考.方法 配制不同含量的金龟子绿僵菌CQMa421饵剂,分别在实验室和现场环境研究其对德国小蠊种群数量的影响,采用SPSS 25.0软件对死亡率、半数致死时间(LT50)、半数致死浓度(LC50)和90％致死浓度(LC90)进行分析,评价金龟子绿僵菌CQMa421饵剂杀蟑效果;采用x2检验分析不同组别间死亡率的差异.结果 室内实验结果表明,1×108孢子/g金龟子绿僵菌CQMa421饵剂喂食德国小蠊后12d,其LT50均值为(6.85±0.24)d;现场实验中,采用每2.5 m2放置1盒1×108孢子/g的金龟子绿僵菌CQMa421饵剂,药剂投放30 d后,相对密度下降率为93.22％.结论 1×108孢子/g的金龟子绿僵菌CQMa421饵剂可有效控制德国小蠊种群密度.

蜚蠊,俗称蟑螂,作为一种世界性卫生害虫,严重威胁人类身体健康,由于其喜欢隐蔽阴暗生存环境的习性,施放饵剂成为室内灭蟑螂的一种重要方式,但以往常规的化学杀虫剂长期大量使用会对人体和室内环境产生危害,造成蟑螂抗药性的产生.因此,对安全、高效的灭蟑饵剂的开发显得尤为重要.该文综述了目前灭蟑饵剂的研究及应用进展,以期为今后对蟑螂的防制新方法的探索提供帮助.

目的 调查重庆市各疫点发现登革热首例病例开展灭蚊前的媒介伊蚊应急监测结果,为今后的媒介伊蚊监测和疫区引起登革热本地病例传播风险预警提供依据.方法 收集重庆市2019年各疫点首次报告登革热病例后,采取灭蚊措施前的媒介伊蚊监测布雷图指数(BI)和帐诱指数数据,采用SPSS 25.0软件进行数据描述性研究和线性回归分析.结果 所有疫点首次应急监测的平均BI值为11.01,平均帐诱指数为5.10只/(顶·h),两者相关系数(r)为0.517,双侧检验P＜0.05,BI与帐诱指数呈正相关,且有统计学意义.通过两变量线性回归分析,构建BI与帐诱指数回归方程:y(BI) =7.07 +0.82x,F=61.232,P＜0.005.在此基础上将重庆市登革热预警风险划分为4个等级.结论 将BI和帐诱指数进行分级评估对于登革热疫情的预警具有指示作用,在日常防控中将重庆市BI控制在7以下,帐诱指数控制在3只/(顶·h)以下,对减少登革热本地暴发有参考意义.