目的 分析外周血CD8+CD28-T细胞叉头框蛋白p3(Foxp3)mRNA表达与老年肺部感染的关系.方法 选择2019年12月-2021年12月乌鲁木齐市友谊医院收治的老年慢性支气管炎患者200例,根据患者是否合并肺部感染分为感染组(n=135)和未感染组(n=65),比较感染组和未感染组患者及不同肺部感染程度患者外周血CD8+CD28-T细胞水平和Foxp3 mRNA表达水平,检测感染组和未感染组患者血清炎性因子[白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、干扰素-γ(IFN-γ)和转化生长因子-β1(TGF-β1)]水平,分析老年肺部感染患者外周血CD8+CD28-T细胞水平和Foxp3 mRNA表达水平与血清炎性因子水平、临床肺部感染评分(CPIS)的关系.结果 感染组患者外周血CD8+CD28-T细胞水平和Foxp3 mRNA表达水平均高于未感染组患者(P<0.05);不同肺部感染程度患者外周血CD8+CD28-T细胞水平和Foxp3 mRNA表达水平比较,差异具有统计学意义(P<0.05),中、重度感染组高于轻度感染组(P<0.05),重度感染组高于中度感染组(P<0.05);感染组患者血清IL-6、IFN-γ水平均高于未感染组患者(P<0.05),IL-10、TGF-β1水平均低于未感染组患者(P<0.05);Pearson相关检验结果显示,CD8+CD28-T细胞水平和Foxp3 mRNA表达水平与血清IL-6、IFN-γ水平、CPIS评分呈正相关(P<0.05),与IL-10、TGF-β1水平呈负相关(P<0.05).结论 老年肺部感染患者外周血CD8+CD28-T细胞Foxp3 mRNA表达显著上调,且与肺部感染程度存在密切关系.

目的 观察耳三针提插补法辅助治疗脾胃虚弱型耳鸣的临床疗效.方法 选取2016年4月—2020年4月期间新疆医科大学附属中医医院针灸科就诊的94例脾胃虚弱型耳鸣的患者,将这94例患者按随机数字表方法随机分为治疗组与对照组.对照组47例患者给予益气聪明汤治疗,治疗组47例患者在对照组基础上加用耳三针辅助治疗,疗程均为2个月.治疗后,观察两组患者临床疗效、治疗前后症状评分、THI评分及不良反应.结果 治疗后治疗组总有效率为86.67％,对照组总有效率为66.67％,差异有统计学意义(P<0.05);治疗后两组患者症状评分、THI评分较本组治疗前明显下降,且治疗组较对照组下降更明显,差异有统计学意义(P<0.05).两组患者均未出现不良反应.结论 耳三针提插补法辅助治疗可明显降低患者症状积分及THI积分,降低患者听力障碍的程度,提高临床疗效.

目的 观察隔姜灸治疗寒凝血瘀性盆腔炎的临床疗效;方法 将200例寒凝血瘀性盆腔炎患者随机分为2组,分别采用隔姜灸治疗和中药灌肠治疗,比较两组临床疗效.结果 两组施灸中期与施灸后1月症状量化评分和体征量化评分分值均显著低于治疗前(P<0.05),且观察组施灸中期与施灸后1月分值显著低于对照组(P<0.05),两组施灸中期与施灸后1月McGill疼痛量表分值均显著低于治疗前(P<0.05),且观察组施灸后1月分值显著低于对照组.结论 隔姜灸治疗能够显著改善盆腔炎患者症状和体征,临床效果显著,操作简便,价格低廉,值得临床推广.

Objective To investigate the effect of acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture on the cLinicaL efficacy and sLeep quaLity of depressive patients. Methods A totaL of 64 patients who met the incLusion criteria were randomLy divided into two groups, 32 in each group. The controL group was treated with routine eLectro-acupuncture, whiLe the observation group was treated with acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture. Both groups were treated for 8 weeks. SLeep quaLity was assessed by Pittsburgh SLeep QuaLity Index (PSQI), and depression was assessed by HamiLton Depression ScaLe (HAMD) to evaLuate the cLinicaL efficacy. ResuLts After treatment, the HAMD score (11.3 ± 2.4 vs. 14.5 ± 2.6, t=4.986) and PSQI index (9.6 ± 2.3 vs. 11.8 ± 2.5, t=3.307) in the observation group were significantLy Lower than those in the controL group (P<0.01). The quaLity of Life (12.9 ± 2.3 vs. 11.3 ± 2.5, t=2.598) and mentaL heaLth score (13.5 ± 2.4 vs. 11.3 ± 2.6, t=3.413) of WHOQOL-BREF scaLe in the observation group were significantLy higher than those in the controL group (P<0.01). The totaL effective rate was 93.8% (30/32) in the observation group and 75.0% (24/32) in the controL group. There were significant differences between the two groups (χ2=4.246, P=0.038). ConcLusions Acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture can effectiveLy improve depressive state, sLeep quaLity and quaLity of Life in patients with depression, and the curative effect is better than conventionaL eLectro- acupuncture treatment.

目的 探讨梅花针叩刺联合闪罐治疗周围性面瘫的疗效观察.方法 选择我院收治的160例周围性面瘫患者作为研究对象,随机分为观察组和对照组,各80例,对照组患者给予毫针针刺结合梅花针叩刺治疗,观察组在对照组的基础上给予闪罐治疗.观察两组患者治疗前后的改良Portman评分以及各相关项目评分的变化,分析治疗前后两组患者的面部对称性评分差异,比较两组患者的临床疗效.结果 治疗后两组患者的总改良Portman评分以及各相关观察项目评分均明显升高,而观察组患者升高更为显著(P＜0.05);治疗后两组患者静态下以及随肌运动下的面部对称性评分均显著降低,而观察组患者的面部对称性评分降低更为显著(P＜0.05).观察组的治疗总有效率明显高于对照组(P＜0.05).结论 梅花针叩刺联合闪罐治疗面瘫可以显著缓解患者临床症状,改善面部对称性,增强临床疗效.

在社会老龄化压力下,医养结合养老模式的实施势在必行.康复治疗技术专业人才培养需求日益增长,新疆阿克苏职业技术学院积极探索构建"三结合,三培养,一专多能,创就并举"的人才培养模式,实施"工学交互"的分段式实训教学模式,以职业标准和行业规范为依据加强课程体系建设,建设高仿真、"创就并举"的实践教学基地,加强专家引领的"专兼结合、校企互通"的"双师型"教学团队建设,对医养结合养老模式下新疆康复治疗技术专业人才培养模式进行探索与实践.

目的:观察佛手定痛汤结合针灸、耳穴敷贴法治疗紧张型头痛的效果.方法:将我院自2015年1月～ 2017年8月收治的紧张型头痛患者纳入研究范围,将其就诊编号按随机分层法分为观察组(n=47)与对照组(n=50),对照组给予针灸、耳穴贴敷,观察组则在此基础联合佛手定痛汤,对比两组治疗前后主症、次症、兼症等症状的中医症候积分、头痛发作次数、持续时间及急性止痛药物服用天数,并于治疗前后进行头痛影响实验(HIT)及症状自评(SCL-90)量表、生活质量(SF-36)量表评分,对比OAB患者头痛影响程度及心理状态、生活质量.结果:治疗后,①两组主症、次症、兼症等症状的中医症候积分及头痛次数、头痛持续时间、急性止痛药物使用天数均显著下降,且观察组低于对照组;②两组HIT实验影响力等级均显著改善,且观察组改善程度优于对照组;③两组SCL-90量表各维度分值均显著下降,且观察组低于对照组;④两组SF-36量表各维度分值均显著上升,且观察组高于对照组,上述对比差异均有统计学意义(P＜0.05).结论:佛手定痛汤结合针灸、耳穴敷贴法治疗紧张型头痛能获取更佳的症状缓解获益,可有效改善患者心理状态及生活质量.

目的:观察穴位埋线干预肥胖型高血压的疗效.方法:将60例肥胖型高血压患者随机分成对照组和治疗组,每组30例,对照组患者口服高血压常规治疗药物,治疗组患者在此基础上加用穴位埋线治疗,1个月为1个疗程,观察比较治疗3个疗程后两组患者的症状、体征、血压、肥胖指标变化以评估疗效.结果:与治疗前相比,两组患者血压均得到良好控制,且治疗组患者各项症状、体征改善情况显著优于对照组,差异具有统计学意义(P<0.05).结论:穴位埋线对肥胖型高血压具有良好的干预效果.

Objective To evaluate the efficacy of acupoint catgut embedding combined with abdominal massage in the treatment of female abdominal obesity with spleen deficiency and dampness. Methods A total of 300 female abdominal obesity patients who met the inclusion criteria were divided into observation group (200 cases) and control group (100 cases) according to the ratio of 2:1 by random number table. The control group was treated with abdominal massage, while the observation group was treated with acupoint catgut embedding on the basis of the control group. The changes of body weight, waist circumference, waist-hip ratio, BMI, FPG, TC and TG levels before and after treatment were compared between the two groups, and the clinical efficacy was evaluated. Results After treatment, the body weight, waist circumference, waist-hip ratio and BMI of the observation group were significantly lower than those of the control group (t values were 10.869, 6.058, 2.941, 21.267, P<0.01 or P<0.05), and the serum levels of FPG, TC and TG were significantly lower than those of the control group (t values were 21.147, 18.325, 19.931, P<0.01). The total effective rate was 91.5％ (183/200) in the observation group and 65.0％ (65/100) in the control group. There was significant difference between the two groups (χ2=32.671, P<0.001). Conclusions Acupoint catgut embedding combined with abdominal massage can improve the obesity index and blood lipid level of women with abdominal obesity, and the curative effect is better than that of abdominal massage alone.

Objective It is to observe the effects of warm-needle moxibustion on changes of behavior as well as TNF-α and MMP-3 in cartilage of SD rats with knee osteoarthritis.Methods Ninety cases of SD rats were included and were divid-ed into three groups at random:normal group,model group and therapeutic group.In each group,there were 30 cases of SD rats.Rat knee osteoarthritis(KOA)model was established by injection of papain solution into the right knee joint.After the models were successfully established, the rats in therapeutic group were treated with warm-needle moxibustion for 2 weeks,the ones in the other two groups were given no intervention.The changes of behavior of all the rats before interven-tion and 2 weeks after intervention were evaluated by Lequesne MG scales.The rats were ultimately sacrificed at the end of experiment and their cartilage tissue in right knee joint was obtained and samples were sliced and dyed.Moreover, they were observed under optical microscope.Radio immunoassay method was used in measuring the level of TNF-αand MMP-3 in cartilage.Results After treatment for 2 weeks,the scores of Lequesne MG scales were significantly lower than that be-fore treatment in model group and therapeutic group(P<0.05), the decrease of the scores in the therapeutic group was much more obvious than that in the model group(P<0.05).The pathological changes of the therapeutic group were more minimal and slighter than that of the model group.The level of TNF-αand MMP-3 in cartilage of SD rats in therapeutic group was significantly lower than that in model group(P<0.05).Conclusion Warm-needle moxibustion can help to re-store the cartilage histomorphology of SD rats with knee osteoarthritis,which is also responsible for its effect in preventing and curing cartilage degeneration.

目的:探讨针灸联合尼尔雌醇片治疗围绝经期综合征的疗效及对患者生殖激素的影响.方法:92例围绝经期综合征患者依据随机数字表法分为对照组和治疗组,对照组予尼尔雌醇片治疗,治疗组予针灸联合尼尔雌醇片治疗,均治疗3个月.比较两组疗效、治疗前后临床症状评分及生殖激素水平.结果:治疗组总有效率显著高于对照组(P＜0.05);治疗后治疗组中医证候评分、Kupperman指数、LH及FSH水平均显著低于对照组,E2水平显著高于对照组,差异均有计学意义(P＜0.05).结论:针灸联合尼尔雌醇片治疗围绝经期综合征,可有效提高临床效果,改善患者临床症状及生殖激素水平.

Objective:To investigate the protective effect of acupuncture and moxibustion combined with massage on symptom improvement and neurological function in middle-aged and elderly patients with lumbar disc herniation.Methods:90 patients with lumbar intervertebral disc herniation who underwent treatment in our hospital from January 2015 to December 2016 were selected as the subjects.The selected subjects were divided into observation group and controlled group according to the random number table method,each group had 45 cases.The patients in the observation group were treated with acupuncture and moxibustion and the controlled group was treated with acupuncture alone.The patients were observed with VAS,lower back pain MJOA score,Oswestry score,treatment time and recurrence.Results:The effective rate (93.33％) was significantly higher than that of the controlled group (71.11％),the difference was statistically significant (P ＜ 0.05).After treatment,the two groups of patients with pain VAS score,lower back pain M-JOA score,straight leg raising angle were significantly improved,VAS,MJOA score of the observation group (1.38±0.32,16.36±5.24) lower than that of the controlled group (3.36±0.64,19.29-±4.73),and the observation group straight legs raise the angle (72.64±16.73°) was higher than the controlled group (55.15±15.28°),the difference was statistically significant (P ＜ 0.05).After treatment,the Oswestry scores of the two groups were significantly decreased,and the Oswestry score (5.49±1.15) in the observation group was lower than that in the controlled group (14.27±2.41),the difference was statistically significant (P ＜ 0.05).The observation group treatment time (36.29 ± 3.57)d was shorter than that of the controlled group (54.32±5.44) d,and the recurrence rate (4.44％) was lower than that of the controlled group (17.78％),the difference was statistically significant (P ＜ 0.05).Conclusion:Acupuncture combined with massage in the treatment of middle and old lumbar disc herniation is effective,can effectively relieve pain,improve clinical symptoms,promote the recovery of lower limb function,and the recurrence rate is low,worthy of clinical application.

目的:观察针灸辅助常规西药治疗单纯后循环缺血性眩晕的临床疗效.方法:选取100例符合纳入标准的单纯后循环缺血性眩晕患者作为观察对象,随机分为对照组50例和观察组50例.对照组给予常规西药治疗,观察组在对照组基础上给予针灸辅助治疗.比较对照组和观察组患者临床疗效及椎基底动脉血流速度.结果:临床疗效评价显示,观察组患者治疗总有效率明显高于对照组(96.0％vs84.0％,P<0.05).与对照组相比,观察组患者治疗后左侧椎动脉、右侧椎动脉及基底动脉血流速度提高,组间比较都有统计学差异(P均<0.05).结论:针灸辅助常规西药在单纯后循环缺血性眩晕患者中应用效果良好,治疗有效率高,而且能够提高椎基底动脉血流速度,临床上值得应用.

目的 探讨针刀治疗对慢性软组织患者疗效及其血清中肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-1β及IL-6水平的影响.方法 216例明确诊断慢性软组织损伤患者按随机数字表法分为对照组与观察组,对照组予以常规治疗,观察组予以针刀治疗.分别观察2组患者总有效率、治疗前后疼痛视觉模拟评分(VAS评分)、治疗后疼痛缓解时间及功能恢复时间间差异,同时比较2组患者治疗前、治疗后3 d及治疗后7 d TNF-α、IL-1β及IL-6变化情况,分别观察2组患者治疗过程中不良事件发生情况.结果 观察组患者治疗总有效率、治疗后VAS评分、治疗后功能恢复时间均较对照组显著改善(P<0.05).炎症指标方面,治疗后3 d 2组患者TNF-α均显著降低,观察组患者IL-1β及IL-6较前显著降低;治疗后7 d 2组患者3个指标均较治疗前及治疗后3 d显著降低.观察组患者3个指标均较治疗后同时点对照组显著降低,差异有统计学意义(P<0.05).2组患者不良事件发生率差异无统计学意义(P>0.05).结论 针刀治疗能显著改善慢性软组织损伤患者的临床疗效,且安全性良好,其机制可能与调节体内炎症因子水平有关.

目的:探讨在痰湿型多囊卵巢综合征(POCS)合并不孕的治疗过程中温针配合周期疗法的应用价值.方法:随机将90例痰湿型POCS合并不孕患者分为两组,以接受西医药物治疗者为对照组,以接受温针配合周期疗法治疗者为治疗组,每组45例.分析两组POCS治疗效果,并随访两组不孕治疗情况.结果:完成3个周期治疗后,治疗组形体肥胖、神疲乏力、头晕胸闷及四肢倦怠积分均低于对照组(P<0.05).同时,完成3个周期治疗并随访1年后,治疗组中医疗效总有效率及妊娠成功率均明显高于对照组,差异具有统计学意义(P<0.05).此外,在3个周期的治疗期间内,两组间治疗相关不良反应发生率比较,差异无统计学意义(P>0.05).结论:相对于西医药物治疗,温针配合周期疗法可有效的提高痰湿型POCS合并不孕的治疗效果.

目的：：观察电针联合西药治疗更年期烘热的临床疗效.方法：收集90例符合纳入标准的更年期烘热患者作为观察对象,随机分为对照组45例和观察组45例.对照组给予西药治疗,观察组在对照组基础上联合电针治疗.疗程结束后,比较两组患者临床疗效及症状积分.结果：更年期烘热临床疗效显示,观察组患者治疗总有效率明显高于对照组(93．3％ vs 77．8％,P＜0．05).治疗后,与对照组相比,观察组患者潮热、汗出、失眠多梦等症状积分显著降低(1．45±0．81 vs 2．53±0．94分,1．21±0．65 vs 2．15±0．87分,1．46±0．74 vs 2．01±0．82分),组间比较都有统计学差异(P 均＜0．05).结论：电针联合西药在更年期烘热中应用效果良好,能够明显提高治疗效果,改善临床症状,临床上值得应用.

Objective: To observe effects of the behaviors of Alzheimer's disease(AD) rats and the activity of superoxide dismutase(SOD),catalase(CAT),the content of malondialdehyde(MDA) in rats' brain tissue and blood serum when apply electroacupuncture(EA) to the points of Shenshu,Fengfu,Zusanli,Sanyinjiao.Methods: To choose 30 healthy male Wistar rats,and divide them into fake surgical operation group,model group and EA group randomly,every group has 10 rats.Model group and EA group injected amyloid protein Aβ1-40 to rats' right side hippocampus to build AD pattern.Fake surgical operation group injected the same dosage of saline in the same position.Model group and fake surgical operation group without any treatment.After two courses treatment,the ability of rats' study and memory in the Y type labyrinth,the activity of SOD and CAT,and the content of MDA in rats' brain tissue and blood serum were determined.Statistical analysis was used.Results: There was no statistically significant in model group and fake surgical operation group before and after treatment;There was statistically significant(P0.05) in EA group compared with model group after treatment.Conclusion: Applying EA to the points of Shenshu,Fengfu,Zusanli and Sanyinjiao,EA could reduce frequency of making AD rats through the test of Y type labyrinth,increase the activities of SOD and CAT,decrease the content of MDA in rats' brain tissue and blood serum.The probably mechanism maybe that EA increased the activity of SOD and CAT's antioxidation system to protect neurone,and strengthened the function of oxyradical's purge system to improve antioxidation ability of body.

目的:观察电针对肾精亏虚型MCI左侧海马NAA/Cr的影响.方法:收集通过神经心理学量表评分及磁共振波谱测定符合轻度认知功能障碍诊断、并属于肾精亏虚型轻度认知功能障碍患者30例,随机分为两组.电针组采用补肾填髓针刺法并接电针;对照组予尼莫地平片剂口服,15 d为1疗程,3个疗程后观察疗效.结果:神经心理学量表评分:电针组、对照组治疗后MoCA和CMS得分均高于治疗前.经统计学分析,电针组治疗前后有显著性差异(P<0.01),对照组治疗前后显著性差异(P<0.05).治疗后两组间差异有统计学意义(P<0.05).磁共振波谱测定:在左侧海马,电针组治疗前后NAA/Cr显著性差异(P<0.05),而对照组无显著性差异(P>0.05),且治疗后两组间差异有统计学意义(P<0.05).结论:神经心理学量表评分显示:两组经治疗后均能改善认知功能,其中电针组疗效较好.电针四神聪、肾俞、风池、太溪穴,可改善轻度认知功能障碍患者的认知能力.应用磁共振波谱测定电针治疗可在一定程度上提高NAA/Cr,表明电针治疗可能是通过修复神经元达到改善认知功能的目的.

<正>1现状分析《针灸治疗学》是从《针灸学》分化出来的分支学科,在开设本课程的初期,其教学方式仍沿循传统的教学模式。针灸治疗学课时为108学时,实践课