This study aims to investigate the trends in sperm concentration among fertile Chinese males over the past four decades, addressing whether there has been a change in sperm concentration and identifying potential causes. The research included 94 Chinese and English literature sources, covering 27 provinces and cities across China, encompassing a total of 14,634 individuals. A least squares linear regression model was applied to analyze sperm concentration data. The analysis indicated a significant downward trend overall from 1984 to 2023 (P = 8.42e − 10). A single-factor analysis of variance was performed, categorized by the year of sample collection, showing a decline in sperm concentration across each decade of the collection years (P = 1.01e − 08), with the most significant decline noted between 2004 and 2013 (P = 0.0035). The findings suggest a general decline in sperm concentration among fertile Chinese males over the past forty years, with a more pronounced decline after the twenty-first century, potentially associated with escalating environmental pollution due to heavy industrialization, poor lifestyle habits, and radiation from electronic devices. Further research is essential to elucidate the causes of and broader implications associated with this downward trend.

ObjectiveThis study aimed to evaluate the spatiotemporal distribution of patients with hepatitis C virus (HCV) and the factors influencing this distribution in Jiangsu Province, China, from 2011 to 2020.MethodsThe incidence of reported HCV in Jiangsu Province from 2011 to 2020 was obtained from the Chinese Information System for Disease Control and Prevention (CISDCP). R and GeoDa software were used to visualize the spatiotemporal distribution and the spatial autocorrelation of HCV. A Bayesian spatiotemporal model was constructed to explore the spatiotemporal distribution of HCV in Jiangsu Province and to further analyze the factors related to HCV.ResultsA total of 31,778 HCV patients were registered in Jiangsu Province. The registered incidence rate of HCV increased from 2.60/100,000 people in 2011 to 4.96/100,000 people in 2020, an increase of 190.77%. Moran's I ranged from 0.099 to 0.354 (P < 0.05) from 2011 to 2019, indicating a positive spatial correlation overall. The relative risk (RR) of the urbanization rate, the most important factor affecting the spread of HCV in Jiangsu Province, was 1.254 (95% confidence interval: 1.141–1.376), while other factors had no significance.ConclusionThe reported HCV incidence rate integrally increased in the whole Jiangsu Province, whereas the spatial aggregation of HCV incidence was gradually weakening. Our study highlighted the importance of health education for the floating population and reasonable allocation of medical resources in the future health work.

BackgroundStarting in 2010, the Chinese government initiated a 10-year syphilis control plan, called the national syphilis control plan (NSCP), to address the emerging threat of syphilis. We aimed to evaluate the effect of the NSCP plan on syphilis control in Jiangsu, China.MethodsThe temporal trends of syphilis incidence, prevalence and rate of condom use were estimated by Joinpoint regression with average annual percent change (APC) and average annual percentage (APPC). A Chi-square test was conducted to analyze the outcomes in different subgroups. ArcGIS was used to analyze the spatiotemporal distribution of syphilis incidence.ResultsGeographically, early and congenital syphilis incidence decreased significantly in all areas of the province during the period of NSCP. Early syphilis incidence decreased from 21.1 to 8.8 (APC: −7.5, 95%CI: −8.6, −6.5, p < 0.001) per 100,000 people, and congenital syphilis decreased from 63.6 to 4.1 (APC: −14.8, 95%CI: −20.8, −8.4, p < 0.01) per 100,000 newborns from 2010 to 2020. Also, syphilis prevalence reduced from 13.4 to 3.8% (APC: −8.7, 95%CI: −12.1, −5.0, p = 0.001) among men who have sex with men, from 5.3 to 1.7% (APC: −7.9, 95%CI: −11.7, −3.8, p = 0.002) among female sex workers and remained under 1.0% with slight variations among pregnant women (APC: 0.3, 95%CI: −4.3, 5.1, p = 0.877) from 2010 to 2020. 0.2% (2,436) of pregnant women who received free syphilis testing during pregnancy were diagnosed with current syphilis infection, and 97.0% (2,555) of newborns in the province were delivered to women diagnosed with syphilis. 91.8% (2,346) of live babies and about 90% of diagnosed patients received complete standard syphilis diagnosis and treatment services.ConclusionTrends of early syphilis incidence and syphilis prevalence show a considerable decreasing trend among almost all the key populations after implementing NSCP. Congenital syphilis has significantly decreased as well and hence, the NSCP program should be sustained and strengthened to control the syphilis epidemic in China further.

目的 了解江苏省不同流动性暗娼人群相关知识行为及其性传播疾病感染因素.方法 收集2016-2021年江苏省暗娼人群哨点监测数据,并根据在当地工作时间的差别进行分层,利用SPSS 23.0统计学软件进行数据整理和分析.结果 2016-2021年共监测66647人,年龄(31.5±8.6)岁.在本地工作1年以上暗娼居多(44.0％),三类人群在年龄构成比方面差异有统计学意义(x2=3393.020,P＜0.05),本地工作不足6个月的暗娼外省到江苏省务工比例,高于另外两组人群,差异有统计学意义(x2=2955.473,P＜0.05).暗娼人群总体艾滋病知识知晓率(93.9％)、最近1个月坚持使用安全套比例(76.0％)以及最近1年接受过艾滋病干预服务比例(94.3％)均呈逐年上升趋势(x2=380.748、4879.812、681.008,P＜0.05),检出艾滋病病毒(HIV)感染率为0.5‰,梅毒感染率为2.2％.多因素logistic回归分析结果,年龄段在40～49岁、非本省户籍、小学及以下文化水平、在本地工作不足6个月、吸毒、未坚持使用安全套、中低档次场所、缺乏艾滋病知识及未接受过艾滋病相关干预防服务是暗娼感染性传播疾病的相关因素.结论 江苏省仍有部分暗娼人群存在"知行分离"现象,且安全套坚持使用率仍有待提高.应对流动性较大的暗娼人群,开展有针对性的场所干预,控制艾滋病性病疫情蔓延.

Objective To analyze the characteristics of HIV/AIDS-associated deaths in Jiangsu Province by evaluating the mortality trend and spatiotemporal distribution, and provide the scientific basis for controlling AIDS deaths.Methods The cumulative number of HIV/AIDS-associated deaths in Jiangsu Province was screened from the basic information system of AIDS prevention and treatment. The relevant information about the dead patients was obtained and analyzed. Results By the end of 2020, there were 4 556 HIV/AIDS-associated deaths in Jiangsu Province, of which 83.98% were males. The mean age at death was 49（38, 61） years. The source of HIV case detection was mainly from testing of other attenders in medical setting, accounting for 50.11% of total deaths. Death with the first CD4 cell count after HIV detection ＜200 cells/mm3 accounted for 55.01%. 53.86% did not receive ART at the time of death. 60.34% of deaths occurred within 1 year after HIV diagnosis. AIDS-associated deaths accounted for 28.05%. The three age groups（≤14 years old, 15-64 years old, and ≥65 years old） had significant differences in the route of HIV detection, first CD4 cell count, whether ART being received, survival time after diagnosis, and cause of death（P all ＜0.001）. From 2013 to 2020,crude mortality, standardized mortality and crude mortality of HIV/AIDS patients aged ≥65 increased from 0.42/100,000,0.41/100,000, and 0.44/100,000 in 2013 to 0.58/100,000, 0.54/100,000 and 1.37/100,000 in 2020, with an upward trend（t=6.46, P=0.001; t=5.50, P=0.002; t=6.66, P=0.001）. The number of deaths was higher in southern Jiangsu, but the cumulative proportion of deaths was highest in northern Jiangsu. In some areas of Nantong and Suzhou, there was a highhigh cluster of deaths. Conclusions The mortality rate of HIV/AIDS patients in Jiangsu Province is increasing. The number of deaths in Nantong City and Suzhou City showed a local cluster effect. Targeted scale-up testing, early detection of patients, and increased treatment coverage remain key strategies to control AIDS deaths.

BackgroundFemale sex workers (FSWs) are considered highly vulnerable to sexually transmitted infections (STIs), but available data on the prevalence of STIs among FSWs in China is limited at a provincial level. This study aimed to evaluate the prevalence of STIs and risk factors among FSWs in Jiangsu, China.MethodsWe conducted a multicenter cross-sectional study in seven cities of Jiangsu to investigate the prevalence and risk factors associated with HIV and other STIs. Blood and urine were collected to test for HIV, syphilis, Hepatitis C (HCV), Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections.ResultsWe enrolled 3,580 FSWs. The overall prevalence of bacterial STIs was 6.2% (5.4%−7.0%). The prevalence of HIV, syphilis infection, HCV, NG and CT were 0.1% (95%CI, 0.0–0.2), 1.8% (95%CI, 1.4–2.3), 0.3% (95%CI, 0.1–0.5), 0.3% (95%CI, 0.2–0.5) and 4.3% (95%CI, 3.6–5.0), respectively. Most FSWs (85.6%) reported consistent condom use with clients in the past month. Only 10.6% of FSWs reported group sex, and 68.3% self–reported HIV testing in the previous year. According to the multivariable model, having group sex in the past year (aOR, 2.521, 95%CI: 1.366–4.651) and HIV infection (aOR, 26.260, 95%CI: 2.432–283.563) were associated with a higher risk of syphilis infection. Migrants (aOR, 1.669, 95%CI: 1.163–2.395), having a history of STIs in the past year (aOR, 4.601, 95%CI: 1.003–21.118), and NG infection (aOR, 38.549, 95%CI: 11.214–132.514) were associated with a higher risk of CT infection. On the contrary, FSWs aged older than 25 were associated with lower risk of syphilis infection (25–34: aOR, 0.339, 95%CI: 0.151–0.763) and CT infection (25–34: aOR, 0.503, 95%CI: 0.316–0.802; ≥35: aOR, 0.578, 95%CI: 0.362–0.925).ConclusionThis study's prevalence rates of syphilis and CT infections show the need to promote comprehensive STIs control and prevention strategies, including behavioral intervention and STIs screening, especially in younger high–risk populations. With the increasing coverage of HIV testing, integrating other STIs screening with HIV testing may be a reasonable way to implement comprehensive STIs control and prevention.

BackgroundThis study aimed to assess the trends and determine the factors associated with late presentation (LP) and advanced HIV disease (AHD) among newly diagnosed people living with HIV (PLWH) from 2008 to 2020 in Jiangsu, China.MethodsNewly diagnosed PLWH registered in the HIV surveillance system from 2008 to 2020 were included. Multivariable logistic regression models were used to analyze the factors associated with LP and AHD. The LP and AHD trends were assessed using Joint-point analysis.ResultsOf 37,251 newly diagnosed PLWH identified, 30,251(81.2%) patients met the inclusion criteria. Among those, 16,672 (55.1%) were considered LP, and 8,691 (28.7%) had AHD. LP trends steadily increased from 2008 (39.0%) to 2020 (59.4%), but AHD trends decreased visibly from 2016 (32.3%) to 2020 (23.4%). The overall median CD4 trends decreased slowly from 389 to 305 cells/mm3 between 2008 and 2020. Married patients and those older than 35 years were more likely to be LP and have AHD. Patients infected via heterosexual transmission had a higher risk of being classified as AHD (aOR: 1.13, 95%CI: 1.06–1.21) than patients infected via homosexual transmission. Patients that were diagnosed at sexually transmitted infections (STIs) clinics (aOR: 1.10, 95%CI: 1.01–1.20) and in hospitals (aOR: 1.69, 95%CI: 1.59–1.79) were more likely to be classified as LP compared with patients diagnosed at voluntary counseling and testing (VCT) centers. Similar, patients diagnosed at STIs clinics (aOR: 1.23, 95%CI: 1.11–1.36) and hospitals (aOR: 2.27, 95%CI: 2.12–2.43) were more likely to have AHD than patients diagnosed in VCT.ConclusionOur findings indicate an alarming burden of LP in Jiangsu, suggesting the need for more attention toward HIV diagnosis at early CD4 stages. National HIV control programs must strengthen comprehensive interventions for HIV prevention and promote HIV services. Also, strategies for HIV prevention (PrEP and PEP), testing, and treatment must be extended, especially among the general population.

我国自1977年首例淋病报告以来,淋病报告病例数逐年增加,范围逐渐扩大[1].2004-2012年,淋病报告发病率呈逐年下降趋势,由2004年的17.71/10万下降到2012年的7.07/10万,年均下降10.84％[2].自2013年起,全国淋病报告发病率从7.61/10万上升到2017年的10.36/10万,年均增长8.02％,2017年淋病的报告发病数居甲乙类传染病报告数第5位[3-6].江苏省淋病疫情与全国变化趋势类似,2004-2012年年均下降20.47％,2013-2017年淋病报告发病率年均增长10.49％[7-8].为了解江苏省淋病报告疫情上升与检测量的关系,科学评估疫情变化影响因素开展此项调查.

目的 通过时间序列预测模型,评估新冠防控措施对淋病流行趋势的影响.方法 收集2010年1月-2020年12月江苏省传染病监测系统中淋病的报告病例数,采用R语言进行自回归移动平均乘积季节(ARIMA)模型构建及验证,卡方检验分析疫情变化特征.结果 淋病AIRMA最适模型为ARIMA(0,1,1),(0,1,1)12.2020年一季度、二季度淋病报告病例数较预测值分别减少59.67％、12.57％.新冠流行主要导致25～44岁年龄组、流动人口、非综合性医疗机构淋病报病数显著下降.结论 重大突发公共卫生事件对性病就医具有一定程度的影响.

Background: To help inform regarding HIV self-testing (HIVST) upscale, we assessed the determinants of recent HIVST uptake among men who have sex with men (MSM) in Jiangsu province, China. Methods: We conducted a convenience online survey from March to April, 2020 among men aged ≥16 years, who had ever had sex with other men. Statistical analysis included Pearson's chi-square test, bivariate correlation, and multivariable logistic regression. p < 0.05 was considered statistically significant. Results: Of the total 692 participants, 69.5% (481) were aged between 18 and 40 years, and 65.9% (456) had reportedly ever self-tested. Using HIVST for first HIV test (aOR = 1.98, 95% CI: 1.21–3.26), perceiving HIVST as more private (aOR = 1.41, 95% CI: 0.85–2.35), and users not needing to go to a health facility (aOR = 1.68, 95% CI: 1.20–2.34) were associated with recent HIVST as facilitating factors. Conclusion: HIVST uptake rate has increased among Jiangsu MSM and can be further promoted by healthcare workers routinely recommending HIVST to their clients.

BACKGROUND:In recent years, a boom of synthetic drugs, especially methamphetamine has been documented in China, however, the situation in Jiangsu was unclear. The objective of this study was to evaluate the changing trends in types of drug used, examine the prevalence trends of HIV, syphilis and HCV over time and compare the demographic, drug and sexual behaviors among different types of people who use drugs (PWD) in Jiangsu Province, China.METHODS:Consecutive cross-sectional studies were conducted from 2011 to 2015 in nine compulsory detoxification centers, which were HIV sentinel surveillance sites, in Jiangsu Province, China. A structured questionnaire was administered in a face-to-face interview with each participant to collect demographic, behavioral and laboratory information. Participants were classified into three types: opioids PWD (using heroin, opium, morphine and dolantin); stimulant PWD (using cocaine, methamphetamine, methylene dioxymetham-phetamine and Magu); poly-drug PWD (using opioids and stimulant drugs simultaneously).RESULTS:Among a total of 16,164 PWD recruited from 2011 to 2015, the proportion of opioids PWD declined from 40.1% in 2011 to 11.8% in 2015, while the proportion of stimulant PWD increased from 53.6% to 84.3%. Overall HIV, syphilis, and HCV prevalence for the period was 0.3%, 9.6% and 31.6%, respectively. As types of drugs used shifted from opioids to stimulants, HIV prevalence increased (P = 0.031) while HCV decreased (P<0.001). HIV, syphilis and HCV prevalence trends varied across the three subgroups. Injection and needle-sharing behaviors differed between opioids and stimulant PWD, whereas unsafe sexual behaviors were similar. Poly-drug PWD might have higher risks for these infections due to combinations of unsafe sexual and injection behaviors.CONCLUSION:Although the trend of drugs used have changed over time, HIV, syphilis and HCV infection risk behaviors among PWD still exist. Therefore, traditional intervention strategies should seek to address the challenge of increasing stimulant PWD. Access to convenient testing services, as well as pre- and post-exposure prophylaxis for HIV risk reduction should be improved among PWD. Antiviral treatment for HCV should be added to medical insurance coverage as soon as possible in Jiangsu Province.

Background The COVID-19 pandemic seriously threatens general public health services globally. This study aimed to evaluate the impact of the COVID-19 pandemic on the HIV care continuum in Jiangsu province, China. Methods Data on newly diagnosed HIV persons for analysis were retrieved from Chinas’ web-based Comprehensive Response Information Management System (CRIMS) for HIV/AIDS from 2016 to 2020. We recorded data for the first 3 months (January to March, 2020) of strictly implementing COVID-19 measures from publicly available disease databases of the Jiangsu provincial Health Committee. We used seasonal autoregressive integrated moving average (SARIMA) and exponential smoothing in forecasting the parameters. Subgroup differences were accessed using Chi-square tests. Results Compared to the estimated proportions, the HIV testing rates decreased by 49.0% (919,938) in the first three months of implementing COVID-19 measures. Of an estimated 1555 new HIV diagnosis expected in the same period, only 63.0% (980) new diagnoses were recorded. According to actual data recorded during the said period, 980 positively tested persons received confirmatory tests, of which 71.4% (700) were reportedly linked to care. And only 49.5% (235) out of the expected 475 newly diagnosed HIV persons received CD4 cell count testing. Meanwhile 91.6% (208) of newly diagnosed HIV persons who received CD4 count tests reportedly initiated antiretroviral therapy (ART) compared to the 227 expected. Compared to the same period from 2016 to 2019, PLWH less than 30 years old and migrants were more likely to be affected by the COVID-19 policies. Conclusions The COVID-19 pandemic negatively impacted HIV healthcare systems in Jiangsu, China. Further measures that can counter the impact of the pandemic are needed to maintain the HIV care continuum.

目的:分析江苏省经异性性行为感染艾滋病病毒(human immunodefciency virus,HIV)病例性行为感染方式及经商业异性性行为感染病例确证阳性前后性行为特征.方法:选取2014年1-6月报告经异性性行为感染HIV病例,询问具体感染方式,调查商业异性性传播病例确证前后性行为信息.结果:调查对象以商业异性性传播为主,占57.21％,但女性主要为婚内传播.经商业异性性行为感染病例同时存在固定和临时性行为,商业性行为、固定性行为和临时性行为的比例分别由确证前100.0％、14.35％和17.72％降至确证后7.59％、5.06％和2.95％,但未坚持使用安全套、性伴不告知和不知晓性伴感染状态等传播风险仍然存在.调查对象的感染及感染后的传播均主要发生在本省内.结论:除继续推行现有的干预措施外,还应进一步缩短发现到治疗的时间以及推进“配偶强制告知”政策的落实.

Objectives: To measure prevalence and risk factors of poor mental health, suicidal ideation, and suicide attempt among transgender women in Jiangsu province, China. Methods: We surveyed 250 transgender women with mean age of 27.9 years from July 2018 to May 2019 in Jiangsu province, China. Logistic regression analysis characterized risk factors for mental health, suicidal ideation, and suicide attempt. Results: Many transgender women experienced discrimination, including verbal abuse (56.0%), physical abuse (32.0%), and sexual violence (32.0%) during their lifetime. Classification by the Kessler Psychological Distress Scale found 32.4%% to be in good mental health, while 24.0%, 16.8%, and 26.8% had mild, moderate, and severe psychological distress respectively. In multivariable logistic regression, severe psychological distress was correlated with bisexual orientation (vs. gay/lesbian, aOR = 2.9, 95%CI = 1.5-5.8), being unsure of sexual orientation (vs. gay/lesbian, aOR = 4.7, 95%CI = 1.8-12.8), experience of verbal abuse (aOR = 1.8, 95%CI = 1.1-3.1), and less severe with alcohol use (aOR = 0.6, 95%CI = 0.3-0.9) (P< 0.05). Many transgender women also reported suicidal ideation (22.0%) and prior suicide attempt (25.6%). Compared to no suicidal ideation, moderate (aOR = 4.9, 95%CI = 1.6-15.2) or severe psychological distress (aOR = 38.6) were asso-ciated with prior suicide attempt (P< 0.05). Residing in Jiangsu province (vs. not residing in Jiangsu, aOR = 0.3, 95%CI = 0.1-0.6) and higher income (vs. lower income, aOR = 0.6, 95%CI = 0.4-0.9) were protective factors for suicide attempt (P< 0.05). Conclusion: Chinese transgender women experience high levels of discrimination, abuse, poor mental health, suicidal ideation, and suicide attempts in Jiangsu province. Society-wide interventions need to be developed to mitigate transphobic discrimination among transgender women in China.

目的 了解江苏省跨性别女性人群(MTF)危险行为特征、艾滋病病毒(HIV)检测率及其影响因素,为相关干预的实施提供依据.方法 采用同伴推动抽样法(RDS)在江苏省内招募MTF,用匿名自填问卷收集社会人口学、行为学以及心理健康等方面信息,并采集指尖血进行HIV和梅毒快速检测.结果 共招募符合条件MTF250人,44.00％年龄分布在18～24岁,高中及以下学历占36.80％;47.60％报告服用过激素,18.00％接受过性别重塑手术,34.40％曾被诊断患有抑郁症;调查对象20.80％自述曾从事过性工作;过去一年在与他人发生性行为时或性行为之前饮酒率和毒品使用率分别为37.60％和4.00％;最近6个月多性伴数(≥2个)占35.60％,性行为中无保护性肛交和阴道交发生率为25.60％和5.20％;调查样本HIV感染者占比为14.80％;去除一年前已知HIV阳性者,最近一年HIV检测率为51.72％(120/232),检测阳性者37例,均确诊为阳性.多因素分析显示,从事过性工作[调整比值比(AOR)=2.36,95％可信区间(CI):1.02～5.46]、未服用激素(AOR=2.34,95％ CI:1.24～4.41)、未患有抑郁症(AOR=2.10,95％ CI:1.11～4.02)是促进MTF最近一年接受HIV检测的影响因素.结论 首次在江苏省开展针对MTF人群的调查,显示跨性别女性人群具有感染HIV高风险但较低HIV检测率特征,亟需采取有效干预措施控制艾滋病在该人群中的流行.

目的 了解江苏省梅毒筛查开展情况及梅毒感染状况,为制定梅毒综合防治策略提供依据.方法 对江苏省2016年通过性病综合防治管理信息系统收集的数据进行综合分析.结果 2016年江苏省共筛查梅毒2 077 400人次,其中医疗机构筛查占64.94％,住院筛查、性病就诊者筛查、术前筛查、孕产期筛查占78.21％,常州市、徐州市、无锡市3个地区筛查人次数占61.24％.梅毒抗体单阳率为2.13％,双阳率为0.91％,非医疗机构的梅毒转介率为24.99％.重点人群梅毒抗体单阳率(5.37％)高于医疗机构筛查人群(1.64％)和一般人群(0.82％),差异有统计学意义(P＜0.01),其中重点人群中的强戒/劳教戒毒人员(12.46％)、男男性行为人群(12.29％)的单阳率较高.结论 江苏省应进一步加大梅毒筛查力度,及戒毒人群、男男性行为人群的梅毒防治力度,提高非医疗机构中梅毒阳性者转介率.

Introduction Transgender women may face the highest prevalence of HIV of any population, experiencing a disproportionate burden of disease frequently confirmed in surveys throughout the developing and developed world. However, few studies have been conducted specifically for transgender women in China. This study aimed to measure HIV prevalence and explore risk factors for infection in a diverse sample of Chinese transgender women to help advocate for prevention and care interventions for this population. Methods From July 2018 to May 2019, we adapted a respondent-driven sampling (RDS) approach to recruit a diverse sample of 250 transgender women through chains of peer referrals in two cities of eastern China, Nanjing and Suzhou. Eligible participants (i.e. 18 years of age or older, living in Jiangsu province and assigned male sex at birth but currently self-identified as a gender different from male) completed a self-administered questionnaire on a mobile phone to collect demographic characteristics and risk behaviours and underwent HIV testing. Results and discussion The survey sample was young (82% under age 35 years), with 28.8% having a university degree, 39.2% reporting work at entertainment venues, 47.6% ever having taken hormones and 6.4% being diagnosed with an STI in the last year. One in five (20.8%) reported having engaged in sex work. HIV prevalence was 14.8% (95% CI 10.6 to 19.8), with 75.6% of those testing HIV positive reporting they were already aware of their serostatus. In multivariate analysis, HIV prevalence was significantly higher among transgender women above the age of 24 years, those who work at entertainment venues, who never have taken hormones, and who had been diagnosed with an STI in the last year. Conclusions The prevalence of HIV among transgender women in our study, at 14.8%, is among the highest detected in any population in eastern China. Chinese transgender women may therefore follow the disparity in the burden of HIV noted worldwide. Data support policies to prioritize transgender women for HIV testing outreach, for in-depth research to better understand the specific drivers of infection in this population, and for trans-friendly HIV care and prevention programmes to address their specific needs.

目的 了解江苏省渔民艾滋病防治知识、危险性行为及艾滋病病毒(HIV)感染状况,为渔民的艾滋病综合防治提供科学依据.方法 采用连续抽样方法对目标人群进行现况调查,通过一对一问卷调查收集行为学信息,采用SPSS 22.0软件进行统计学分析.结果 共调查1 514人,平均年龄(49.10±9.54)岁,年龄中位数50岁(19～65岁);已婚者占95.18％,从事渔业年限≥25年占53.70％,初中及以下文化程度占88.64％,本地渔民占93.26％.艾滋病防治知识知晓率为41.22％.最近1年与异性不安全临时性行为发生率为74.06％,寻找异性临时性伴的主要场所为娱乐场所占36.25％,最近1年多性伴异性性行为发生率为17.44％,最近1年同性性行为发生率为2.31％.HIV既往检测率为4.10％,HIV感染率为0.07％,梅毒酶联免疫吸附试验抗体阳性率为2.91％,现症梅毒感染率为0.46％.结论 江苏省渔民艾滋病防治知识知晓率低,既往HIV检测率低,危险性行为发生率高.应着重提高渔民的艾滋病防治知识水平,推广安全套使用,加大HIV筛查力度,防止HIV在该人群的传播蔓延.

利用"江苏疾控"微信公众号平台,进行艾滋病性病防治知识宣传的信息收集、统计模块,收集并整理相关问题;依托互联网+平台,了解江苏省普通人群对艾滋病性病知识知晓、态度和行为学因素.探讨利用新媒体在艾滋病性病宣传教育中的可行性和持续性,结合2016年与2017年两年的实践,对这种宣传和干预方法进行探讨和总结.