目的 对近20年全文期刊数据库和ACCESS肿瘤转移数据库中药治疗肿瘤转移方药进行归纳,探讨肿瘤转移的用药规律.方法 对所选文献的方剂中药物的使用频次、功效归类等规律进行研究,归纳总结肿瘤转移常见证型治法.结果 治疗肿瘤转移常用内服中药前五位是黄芪、甘草、莪术、当归、丹参;具有利水消肿、祛湿化痰功效的药物占40%.结论 肿瘤转移发病机理为痰毒流注,络损血瘀,患者大多有痰湿、气虚、血瘀之征.

Objective To observe the effect of Traditional Chinese Medicinal Compound on the development of morphine tolerance in rats and its mechanism. Methods 30 male km mice from December 2008 to May 2009 were randomly divided into three groups(M group,MB group and control group) with each group 10 mice.All the mice were bred adaptively in a quiet environment with room temperature and normal illumination for one week.And then the mice in the M group were given subcutaneous injection of morphine for 10 mg/kg every 12 h.The mice in the MB group were given subcutaneous injection of morphine for 10 mg/kg as well as Traditional Chinese Medicinal Compound for 0.2 ml/mouse.All the mice were treated 15 times for one week.The control group was not given any treatment.TFL was measured before drug administration and 30 minutes after the 1st,3rd,6th,9th,12th and 15th drug administration respectively.Immunohistochemical method was used to detect PKA. Results The TFL between the two groups showed no statistically significant differences before drug administration and after the 1st and 3rd drug administration(P>0.05).While the TFL between the two groups showed statistically significant differences after the 6th,9th,12th and 15th drug administration(P<0.05).PKA had little expression in cerebral cortex among normal mice according to immunohistochemistry.While the expression of PKA increased in the M group and increased significantly in the MB group.The average OD value of the M group and MB group was(0.3492±0.0055) and(0.3230±0.0096) respectively(t=2.83,P<0.05). Conclusion The Traditional Chinese Medicinal Compound can inhibit the development of morphine tolerance in rats and can achieve satisfactory analgesic effect when combined with morphine.Its mechanism may relate to the antagonism on the influence of signal transduction system by morphine.

Objective:To search the effective way of treating elder patients with functional constipation.Methods:Fifty-eight cases were separated into three degrees.The new theory treatment of constipation through supplementing and Chinese medicine Yangrong Runchang mixture were used for 14 days,and then the efficiency was calculated.Results:The efficiency of Yangrong Runchang mixture was 93.1%.Conclusion:The treatment of elder patients with functional constipation based on the new theory has a significant effect.

Geratic functional constipation should not only is considered aclinical symptoms,but an independent disease.Because there is different understand to constipation between traditional Chinese medicine and western medicine,especially a rational use of Chinese medicine and a variety of Chinese medicine services will make you have more advantages if you are a doctor of traditional Chinese medicine.For example,you will have a clear understanding of the causes,personal treatment,not dependency and side effects,the term effectiveness for stability and avoid the sufferings of operation,etc.The new theory of treatment of constipation through bu's putting forward and the application of Chinese medicine Yangrong Runchang mixture develop Chinese medicine functional system of the theory known.The term effectiveness for stability can be true.The treatment of functional constipation will be pushed forward to a higher level.