目的:观察中药内服、外敷联合刺络拔罐治疗中重度寻常型痤疮的临床疗效。方法:患者随机分为治疗组和对照组,治疗组予中药内服、刺络拔罐和面部中药湿敷疗法后倒模,对照组仅予中药内服,治疗3个月后观察并比较疗效及皮损情况。结果:治疗后2组患者丘疹、脓疱、结节囊肿、粉刺积分及皮损总积分均较治疗前明显降低,治疗组上述各项评分均明显低于对照组;治疗组总有效率明显高于对照组。结论:采用中医综合疗法治疗中重度寻常型痤疮效果优于单纯服用中药,值得临床推广。
肾是生命起源发展之根本,老年肾气渐亏,精气虚衰而有元神失聪,灵机失用,大量临床经验也证实补肾方药对老年痴呆的治疗效果显著.从肾论治老年痴呆,具有理论可行性,并有现代药理学研究对其佐证.进一步从整体探讨方剂配伍的药理作用机制,找到更加有效的配伍及复方,是未来中医药治疗老年痴呆的重要方向.
丹参是唇形科鼠尾草属多年生草本植物丹参(Salviae miltiorrhizae Bunge)的干燥根和根茎,具有活血祛瘀、通经止痛、清心除烦、凉血消痈之功效[1],始载于《神农本草经》,被列为本草上品。用现代科学方法研究丹参的成分、作用始于20世纪30年代,数十年来,经过化学、药学及药理学和临床医学工作者的共同努力,证实丹参具有抗炎、抗氧化、改善微循环等多种功效。近年来,随着临床和实验室研究的深入开展,使丹参在皮肤科领域的运用范围不断扩大,现结合有关文献就丹参多种有效成分、丹参制剂在皮肤科的应用综述如下。
With the development of modern trauma technology,wound dressing not only covers the wound,but more importantly it also has a function to promote wound healing. From the 1960 s to now,many scholars,through a lot of wounds experimental research and clinical practice,have proved that the wound dressing has the function to promote wound healing. How to better implement the wet environment healing theory currently,at the same time,how to make good use of the advantages of traditional Chinese medicine,will be the future direction of the research and development of new wound dressings.
[目的]考察不同血清含量以及培养不同时间对人永生化角质形成细胞(HaCaT)细胞的生长及迁移特性的影响,为HaCaT细胞划痕实验条件优化提供实验数据支撑.[方法]培养HaCaT细胞,按10%血清浓度全培基(全培基阳性对照组)、2%低浓度血清培基(低血清培基组)及无血清培基(对照组)分组,通过进行细胞划痕实验,CCK-8细胞活力检测、Brdu细胞增殖实验,分析HaCaT生长特性.[结果]在24 h内,低血清培基组HaCaT细胞与全培基组相比,细胞增殖能力无明显差异,细胞活力有增高的趋势.细胞孵育48 h后,全培基组细胞增殖能力及活力明显升高.24~48 h,全培基组细胞增殖能力及细胞活力的提升速度明显高于低血清培基组.[结论]培养基中血清含量对HaCaT细胞生长特性及迁移能力具有重要影响,培养24 h内低血清培养条件有利于划痕实验的观察与测定.
[Objective] To establish an acne model of rabbit ear and then observe the therapeutic effect of compound traditional Chinese medicine acne gel. [Methods] Pix carbonis dilution(2% concentration of pix carbonis solution with 95% concentration of alcohol) was applied to inside surface of rabbit ears for successive 14 days to prepare the experimental acne model on rabbit ear. The models were confirmed by both naked eye and pathology examination. They were then divided into group A, B, and C randomly, applying 5% acne gel, 10% acne gel and tretinoin to the lesions respectively. After treatment for two weeks, the acne was classified according to a standard and the therapeutic effects was compared between these three groups. [Results] In contrast, these three treatments showed remarkable therapeutic effects compared with before. But the differences among three groups were not significant. [Conclusion] Compound Chinese medicine acne gel has a specific therapeutic effect on experimental rabbit ear acne models.
蒲黄(pollen tyhae)为香蒲科植物水烛香蒲(Typha angustifolial)、东方香蒲(Typha orientalis presl)或同属植物的干燥花粉。蒲黄药用记载始于《神农本草经》,列为上品;《日华子本草》首载用其炮制品。蒲黄是传统中药,具有止血,化瘀,利尿等功效。在临床上可用于镇痛、抗凝促凝(与浓度有关)、促进血液循环、降低血脂、防止动脉硬化、保护高血脂症所致的血管内皮损伤,抗炎等症。现对蒲黄的药理活性作一综述,以期为蒲黄的进一步研究提供参考。