目的 观察御风固表散联合西替利嗪治疗气虚不固型慢性荨麻疹的临床疗效及对血清总IgE和T淋巴细胞亚群的影响.方法 将60例慢性荨麻疹患者随机分为治疗组和对照组,每组30例.对照组采用口服盐酸西替利嗪片治疗.治疗组在对照组的基础上加用御风固表散口服,每天2次,每次1包.2组疗程均为4周,治疗4周后评估疗效及检测血清总IgE和T淋巴细胞亚群、生活质量指数量表评分(DLQI)以及皮损症状积分.结果 2组治疗4周后症状积分均较治疗前均下降,且治疗组较对照组下降更明显(P<0.05),2组比较差异具有统计学意义.2组治疗前后血清总IgE、DLQI差异具有统计学意义(P<0.05),且治疗组下降更明显.治疗组治疗后外周血CD4+和CD4+/CD8+水平下降,CD8+水平升高,且差异具有统计学意义,对照组治疗前后T淋巴细胞亚群无明显变化,差异无统计学意义.2组治疗总有效率比较,治疗组明显高于对照组,且差异有统计学意义(P<0.05).2组不良反应比较,差异无统计学意义(P>0.05).结论 御风固表散联合西替利嗪治疗气虚不固型慢性荨麻疹疗效优于单纯西替利嗪,且无明显毒副作用,值得临床推广应用.
目的 观察中药袪疣颗粒联合复方甘草酸苷片、火针治疗面部热毒蕴结型扁平疣临床疗效.方法 采用随机数字表法将70例面部热毒蕴结型扁平疣患者分为对照组和观察组各35例.对照组口服复方甘草酸苷片和火针治疗,观察组在对照组治疗基础上口服袪疣颗粒治疗,2组均连续治疗4周.观察2组治疗前后皮损评分和DLQI评分,并比较其疗效和复发情况.结果 2组治疗后皮损评分和DLQI评分较治疗前明显降低(P<0.05),观察组降低程度优于对照组(P<0.05);观察组显愈率(82.86%,29/35)优于对照组(42.86%,15/35)(P<0.05);观察组复发率(18.18%,2/11)低于对照组(66.67%,4/6).结论 中药袪疣颗粒联合复方甘草酸苷片、火针可改善扁平疣皮损程度及其生活质量.
目的:观察中药联合超脉冲CO2点阵激光治疗气滞血瘀型痤疮瘢痕的临床效果.方法:本文选取本科门诊2018-2020年60例痤疮瘢痕患者进行临床观察,随机分成治疗组和对照组,每组30例.对照组予超脉冲二氧化碳点阵激光、外用重组人表皮生长因子溶液,治疗组在对照组的基础上加用中药祛疤颗粒1周,2次/d,治疗间隔2个月后再治疗1周,2次/d,观察两组治疗前后痤疮瘢痕评分及DLQI.结果:治疗组治疗后痤疮瘢痕评分及DLQI评分低于对照组,差异有统计学意义(P<0.05),且治疗组疗效明显优于对照组,差异有统计学意义(P<0.05),两组均未发现明显不良反应.结论:祛疤颗粒联合超脉冲CO2点阵激光治疗气滞血瘀型痤疮瘢痕效果显著,且优于单纯激光治疗组.
脂溢性脱发中医称为蛀发癣,好发于20~30岁的青壮年男性,表现为前发缘后退或头顶部头发稀疏,甚至除发缘外整个头皮的头发全部脱落,常呈进行性,多伴有头发油腻、多屑或轻度瘙痒感[1].2013年10月-2015年10月我们用滋肾生发液治疗脂溢性脱发36例,疗效较好,现报道如下.
Objective: To observe the clinical curative effect of Yufeng Gubiao Zhiyang Granule in the treatment of chronic urticaria with insecurity of deficient qi.Methods: 70 patients with chronic urticaria were randomly divided into the treatment group and the control group,35 cases in each group.The treatment group was given Yufeng Gubiao Zhiyang Granule,the control group oral administration of Qifeng Granule,4 weeks as 1 course of treatment for two groups,the curative effects were tested after 1 course of treatment,the follow-up indicated the recurrence rates 1 month later.Results: The conditions of patients with chronic urticaria in the two groups improved in different degrees,the symptom scores before and after treatment in each group had significant differences(P<0.01).The treatment group was superior to the control group in the comprehensive scores and comprehensive effective rates after the treatment(P<0.01),the total effective rate of treatment group was 87%,while that of the control group was 74%,there was significant difference between the total effective rates of two groups(P<0.05).The recurrence rates of two groups were tested 1 month after the treatment,the recurrence rate in treatment group was 18.2%,significantly lower than that of the control group(66.7%),the difference was statistically significant(P<0.05).Conclusion: Yufeng Gubiao Zhiyang Granule has obvious clinical effect on chronic urticaria with insecurity of deficient qi,without obvious side effects.
2007年10月-2010年8月我科使用自拟清疣汤联合阿维A胶囊治疗顽固性扁平疣,取得较满意效果,现报道如下. 1资料和方法 1.1临床资料 70例患者均为我院皮肤科2007年10月-2010年8月门诊患者,符合赵辨主编<临床皮肤科>中扁平顺疠的诊断标准这[1],且≧18岁,自愿参加者.
Objective To investigate the clinical effect of combination of PGEl and Liu shen pills in the treatment of PHN (post-herpetic neuralgia).Methods Sixty five cases of PHN were divided into treatment group and control group randomly.Both groups were given vancomin 0.5mg per day by muscle injection,Stronger Neo-Minophagen C and Tab vitamin B1 10mg three times daily respectively by oral administration for two weeks,and the treatment group were given PGEl 10ug per day by intravenous drip and Liu shen pills ten pills three times daily in addition for two weeks.Clinical effects of the two groups were evaluated.Results After two weeks of treatment,the clinical effect of the treatment group(71.43%) was significantly better than the control group(46.67%)(P0.05).Conclusion The pain degree,sleeping quality and routine life quality of the post-treatment group were improved significantly compared with the pre-treatment group,that combination of PGEl and Liu shen pills are used to treat PHN was safe and effective.