Objective:To explore the clinical characteristics of children with anaphylactoid purpura.Methods:258 cases of children with anaphylactoid purpura were selected,and the clinical data were retrospectively analyzed.Results:In children with HSP, autumn and winter were the high seasons;the peak age of onset was 6 to 11 years old;upper respiratory tract infection was the main cause;most courses were within 1 month;Shizheng was main in the early stage;Xuere Wangxing was the most common type. Conclusion:We should choose the appropriate Chinese medicine treatment plan according to the clinical characteristics of children with anaphylactoid purpura.

Objective:To observe clinical effects of Qi-replenishing kidney-tonifying and spleen-invigorating prescription in treating children with chronic refractory idiopathic thrombocytopenic purpura (CRITP).Methods:Clinical data of 96 children with CRITP admitted from January,2015 to January,2016 were retrospectively analyzed,according to different therapeutic regimen,42 cases in the control group accepted routine western medicine,and 54 cases of the observation group took Qi-replenishing kidney-tonifying and spleen-invigorating prescription,the values of T lymphocytes,the scales of clinical symptoms,PAlgG,blood platelet counting of the children were compared between both groups.Results:After treating,blood platelet counting,PAlgG and T lymphocytes (CD8,CD4 and CD3) of the children in the observation group improved after treating,the improvements were more obvious compared with the control group(P＜0.05);total scales of clinical symptoms in the observation group were(3.40±0.35),lower than (8.50±1.37) of the control group(P＜0.05).Conclusion:Treating children with CRITP by Qi-replenishing kidney-tonifying and spleen-invigorating prescription could increase blood platelet counting in peripheral blood of the children and play a role in cellular immunological regulation.

目的：探讨羚黄凉血颗粒治疗儿童过敏性紫癜血热妄行证的临床效果。方法：将过敏性紫癜血热妄行证患儿分为治疗组和对照组。对照组51例患儿给予常规西医药治疗，治疗组在对照组基础上联合应用羚黄凉血颗粒治疗，4周后比较两组治疗效果。结果：治疗组总有效率为98．0％高于对照组的78．4％；治疗组总复发1例，低于对照组的10例；治疗组皮疹消失时间、腹痛消失时间、尿常规回复正常时间均有效缩短。结论：羚黄凉血颗粒治疗儿童过敏性紫癜血热妄行证可有效提高治疗效果，缩短病程，改善患儿免疫功能。

临床资料 患儿男,5岁.因周身皮肤黏膜起疹4天,于2006年3月2日收住院.4天前患儿胸部皮肤出现红斑,继而红斑之上出现大小不等松弛水疱,水疱很快破溃,表皮松解、剥脱.皮损迅速扩散,波及面颈部、躯干、四肢,双眼、口唇、外阴部黏膜同时受累.患儿偶感患处疼痛,行走不便.2天前曾在外院就诊,按"脓疱疮"给予罗红霉素口服、百多邦软膏外用,病情加重故来我院就诊.经追问病史,患儿家长诉其起疹前5天曾服小儿鼻炎片(同仁堂生产)、好娃娃颗粒(复方制剂,其中含有"对乙酰氨基酚").患儿自发病以来无发热咳嗽,无腹泻黑便,食欲欠佳.体格检查:T 37.3℃、P 96次/分、R 22次/min,神志清,表情痛苦,心肺(-),肝脾不肿大.皮肤科情况:面颈部、躯干、四肢见大片紫红色斑,其上有多数松弛性大疱、表皮松解、剥脱,如烫伤外观.双眼皮肤发红,球结膜充血,口唇干裂,外阴部皮肤黏膜肿胀破溃.

目的研究小儿CD7抗原阳性急性髓系白血病(CD2+AML)的临床生物学特征及治疗效果.方法对55例初治小儿AML进行细胞形态学、免疫表型、多药耐药P糖蛋白(P170)检测,临床观察,并常规采用HAE方案诱导治疗,判定疗效.结果23例CD7+小儿AML在FAB分型中以M2、M5多见.M3中无一例CD7抗原表达,将CD7+与CD7-两组小儿AML进行对比,CD7+AML具有肝脏明显增大(P＜0.005),外周血白细胞数、原始细胞比例及P-糖蛋白表达增高等特点(P＜0.005,P＜0.01及P＜0.05),且年龄偏低,中位数年龄7.6岁(P＜0.01),治疗效果差,完全缓解率43%,达首次缓解中位时间为55.5天.结论小儿CD7+AML具有独特的临床生物学特征,常表达P-糖蛋白,临床症状重,治疗效果差,完全缓解率低(P＜0.05),达首次缓解时间长(P＜0.05).