Objective:To explore the clinical characteristics of children with anaphylactoid purpura.Methods:258 cases of children with anaphylactoid purpura were selected,and the clinical data were retrospectively analyzed.Results:In children with HSP, autumn and winter were the high seasons;the peak age of onset was 6 to 11 years old;upper respiratory tract infection was the main cause;most courses were within 1 month;Shizheng was main in the early stage;Xuere Wangxing was the most common type. Conclusion:We should choose the appropriate Chinese medicine treatment plan according to the clinical characteristics of children with anaphylactoid purpura.
Objective:To observe clinical effects of Qi-replenishing kidney-tonifying and spleen-invigorating prescription in treating children with chronic refractory idiopathic thrombocytopenic purpura (CRITP).Methods:Clinical data of 96 children with CRITP admitted from January,2015 to January,2016 were retrospectively analyzed,according to different therapeutic regimen,42 cases in the control group accepted routine western medicine,and 54 cases of the observation group took Qi-replenishing kidney-tonifying and spleen-invigorating prescription,the values of T lymphocytes,the scales of clinical symptoms,PAlgG,blood platelet counting of the children were compared between both groups.Results:After treating,blood platelet counting,PAlgG and T lymphocytes (CD8,CD4 and CD3) of the children in the observation group improved after treating,the improvements were more obvious compared with the control group(P<0.05);total scales of clinical symptoms in the observation group were(3.40±0.35),lower than (8.50±1.37) of the control group(P<0.05).Conclusion:Treating children with CRITP by Qi-replenishing kidney-tonifying and spleen-invigorating prescription could increase blood platelet counting in peripheral blood of the children and play a role in cellular immunological regulation.
目的:探讨羚黄凉血颗粒治疗儿童过敏性紫癜血热妄行证的临床效果。方法:将过敏性紫癜血热妄行证患儿分为治疗组和对照组。对照组51例患儿给予常规西医药治疗,治疗组在对照组基础上联合应用羚黄凉血颗粒治疗,4周后比较两组治疗效果。结果:治疗组总有效率为98.0%高于对照组的78.4%;治疗组总复发1例,低于对照组的10例;治疗组皮疹消失时间、腹痛消失时间、尿常规回复正常时间均有效缩短。结论:羚黄凉血颗粒治疗儿童过敏性紫癜血热妄行证可有效提高治疗效果,缩短病程,改善患儿免疫功能。
急性白血病是儿童时期恶性肿瘤中患病率和死亡率最高的疾病,国内每年约有115万例14岁以下的儿童患急性白血病[1]。中枢神经系统白血病是白血病的常见并发症,目前中枢神经系统白血病已成为导致疾病复发的重要因素,且发生率逐年提高[2]。为减少中枢神经系统白血病的发生,患儿须在诱导缓解后行腰穿鞘内注射化疗药物,整个疗程至少需要注射16~24次[3]。腰穿鞘内注射术是一种创伤性操作,患儿会出现头痛、呕吐等不良反应[4]。本科室2011年5月11日收治了1例白血病患儿,患儿在行腰穿鞘内注射化疗药物后10 min突发惊厥,经过积极抢救治疗,患儿病情逐渐稳定。在此期间患儿家属情绪失衡,笔者采用以聚焦解决模式为基础的干预策略对患儿家属进行心理护理。聚焦解决模式是一种以人为本,主张充分利用当事人自身优势和资源达成目标的一种心理干预模式,因为不将干预重点集中在分析问题产生的原因上,从而使得干预过程不同于传统问题解决模式,且短期效果明显[5]。该患儿家属经过实施心理干预,情绪稳定,现将结果报道如下。
Objective: To compare the clinical effect between Shenqishabai Granule combined with national chemotherapy scheme and mere national chemotherapy scheme.Methods: Patients were divided into two groups.Experimental group were treated with Shenqishabai Granule combined with national chemotherapy scheme,and control group were treated with national chemotherapy scheme merely.Then the remission rate of induction chemotherapy,micro-residual disease before early reinforcement and drug withdrawal,infection in chemotherapy,long time survival rate in two groups were observed.Results: The remission rate of first induction and micro-residual disease before early reinforcement in two groups were not statistically different.The disease free survival rate in experimental group was higher than that in control group,but there were no statistical differences because of the limited number.Micro-residual disease of the 82 patients were detected,who were survived three year for on disease before drug withdrawal.The negative rate in experimental group was extremely higher than that in control group.Additionally,the infection rate in experimental group was extremely lower than that in control group.Conclusion: Shenqishabai Granule combined with national chemotherapy scheme on children ALL could increase the effect,decrease the toxicity,improve immunity,reduce infection and remove micro-residual disease.Finally patients could survive long time with no disease.
目的观察水合氯醛加中药保留灌肠治疗小儿表寒里热证外感发热的疗效。方法将患者给予水合氯醛加柴银蒲汤剂保留灌肠,观察退热时间及发生惊厥情况。结果本组治疗总有效率为92.45%,且无1例发生惊厥。结论水合氯醛加柴银蒲汤剂保留灌肠治疗小儿外感发热疗效显著。
小儿泄泻是儿科临床常见病,发病后易耗气伤液,出现伤阴损阳或阴阳两伤等危重变证,甚者危及生命.迁延不愈者可致小儿营养不良、生长发育迟缓、疳疾等.2006-10-2010 -12,我们应用香萸止泻散敷脐治疗小儿泄泻82例,并与西医常规治疗81例对照观察,结果如下.
<正>急性白血病占小儿恶性肿瘤的首位,严重危害儿童健康。目前,小儿急性白血病的治疗主要采取以化疗为主的综合治疗,而化疗药物则会加重肝脏及肾脏损害,化疗导致的肝肾功能异常使化疗间歇期延长,增加患者的经济负担,同时影响了患儿的长期生存,多年来我们在常规化疗同时加用阿拓莫兰保
<正>目前小儿白血病的治疗主要采取以化疗为主的综合疗法,尤其是儿童急性淋巴细胞白血病(ALL),且随着化疗方案的不断完善,越来越准确的危险度和预后因素的评估,使本病的无事件生存率和治愈率取得了显著增长,但化疗后合并感染导致化疗失败乃至患儿死亡仍是不可忽视的问题。尤其是诱导阶段的感染是儿童白血病化疗期间的主要死亡原因[1],针对这一
目的观察柴银蒲解毒汤保留灌肠治疗小儿高热的疗效。方法将患儿随机分为两组,两组均给予常规补充电解质,纠正酸碱平衡等综合治疗。治疗组在基础治疗的同时加用柴银蒲解毒汤保留灌肠,对照组在基础治疗同时给予口服对乙酰氨基酚口服液(百服宁)。结果治疗组疗效优于对照组。结论柴银蒲解毒汤保留灌肠治疗小儿高热疗效显著。
白血病在青少年恶性肿瘤的发病中占居首位,近年来,伴随肿瘤诊治水平的不断提高,对肿瘤病人实施心理行为干预的研究亦日益增多,对肿瘤病人生存质量的关注愈加受到重视.如何通过有针对性的心理行为干预提高肿瘤患儿生活质量,延长生存期,从而达到理想的治疗效果,应该得到临床医生的重视.现将我院儿科2003年6月~2006年1月收治的29例急性白血病进行心理干预,的临床观察情况报道如下:
近年来,我科采用中药、小剂量环孢霉素(CSA)、康力龙联合治疗慢性再生障碍性贫血(CAA)患儿30例,疗效满意,现报道如下.
众所周知,同时应用多种免疫抑制剂进行联合免疫抑制(IS)治疗再生障碍性贫血(再障),尤其是治疗重型再障(SAA),可以进一步提高临床疗效.从1988年2月~2003年8月间,我们采用中药、大剂量静脉注射用人血丙种球蛋白(HD-IVIG)静点与小剂量环孢霉素(GSA)口服联合治疗儿童SAA,取得较好疗效,现介绍如下.
中药灌肠疗法在中医治疗学中属于中药外治范畴,通过药物的渗透、吸收而起到治疗疾病的作用.小儿服用中药较困难,强行灌服易呛入气管或易吐而影响治疗,也有些患儿因疾病本身(如肠梗阻、昏迷)不能服药,此时用中药灌肠可起到较好作用.现将小儿疾病中常用的灌肠疗法总结如下.
噬血细胞综合征(HPS)又称噬血细胞性淋巴组织细胞增生症(HLH)属于组织细胞增生症的第Ⅱ类,近年来小儿报道逐渐增多,现将近期我科收治的三例患儿的诊治体会总结如下:
患儿女,6岁.主因坐、站、行走不稳2d,于2002年8月住院.入院前7d患儿下唇邻近口周皮肤痒痛、色红,随即出现成簇密集分布小米粒大小透明水泡,无发热,当地医院诊断为单纯疱疹,未予治疗,疱疹很快破溃,形成表浅溃疡并结痂.入院前5d,患儿开始坐、站、行走不稳,容易跌倒,无头痛、呕吐,无惊厥及昏迷,无发热.入院查体:体温36.5℃,脉搏90/min,呼吸20/min,血压12/8kPa,神志清,精神弱,少语,语言断续,语音低弱;头、躯干、四肢无震颤,双眼球无水平震颤,双瞳孔等大正圆,对光反射灵敏,下唇邻近口周皮肤有疱疹及结痂;站立时左右摇晃,双足不能并拢,不能独自坐、站立、行走,家长扶走时见双足间距增宽,不能走在一条直线上;轮替试验缓慢,跟膝胫试验、指鼻试验不稳,肌力及肌张力正常,腱反射正常,脑膜刺激征阴性,病理反射阴性.脑脊液检查常规及生化均正常,脑电图及脑CT检查正常,诊断为急性小脑共济失调,应用营养脑细胞药物及支持治疗,16d后完全恢复正常.