中医认为,多发性骨髓瘤根本病因为肾虚,病位在骨髓,病机为肾虚血瘀.任督二脉属于奇经八脉,与人体脏腑、气血阴阳息息相关.任督二脉与本病的病因、病机、病位密切相关.文中从任督二脉论治多发性骨髓瘤,针刺治疗重视任督二脉的作用,选取任督二脉的腧穴,并适当配合脾、肾经穴位以补虚固本,为针灸治疗多发性骨髓瘤临床选穴提供了一种新思路.

The position of Xuehai (SP10) is clear, but its locating method is vague, resulting in the disunity of clinical application and even possibly affecting the curative effect. Also, when learning the meridians and acupoints, the beginners are often confused by this issue possibly due to: ① when the bone-length proportional measurement combined with anatomic symbol (combination method) was adopted, it is not clear that the patient should take a posture of knee extension or knee flexion; ② when the combination method used, it is difficult to find the highest point of muscle eminence in the case of patient with thin vastus medialis muscle and fuzzy body surface projection; ③the simple method for locating SP10 is widely used at present, can it replace the combination method to locate this acupoint accurately？Guided by these questions, we, in the present paper, reviewed the rela-ted textbooks, works and other literature to explore the standard position of SP10, and the standard and simple methods for locating this acupoint. Comprehending various opinions, we hold that SP10 should be positioned under the extended knee posture, then, the acupoint's horizontal ordinate "2 cun superior to the medial end of the base of the patella" is determined by using bone-length proportional measurement to measure 2 cun from the bottom to the tip of the patella. Then, the body surface anatomic symbol method is used, when, the patient is asked to stretch the leg and contract the vastus medialis muscle, the highest spot of muscular eminence is the SP10. If the patient's muscular protuberance is not obvious, the middle line between the medial and lateral margins of the vastus medialis muscle is used as the vertical ordinate, and its intersection with the abscissa is SP10. The simple method is easy in operation and has a reference value, but may frequently produce errors, hence, it is not a substitution for the combination method.

目的 观察针刺序贯疗法对乳腺增生症模型大鼠血清雌二醇(E2)、孕酮(P)水平及乳头高度、直径的影响,探讨针刺序贯疗法治疗乳腺增生症可能的作用机制.方法 将32只SPF级7～8周龄雌性未孕SD大鼠采用随机数字表法分为空白组、模型组、普通针刺组、针刺序贯组4组,每组8只,除空白组外,其余3组大鼠复制乳腺增生症模型.造模成功后,针刺序贯组以屋翳、膻中为主穴,根据大鼠性周期不同阶段配以不同穴位针刺,每日1次,1个性周期为1个疗程,连续针刺3个疗程;普通针刺组针刺膻中、乳根、后三里、三阴交穴,每日1次,疗程同针刺序贯组.针刺结束后,采用放射免疫法检测各组大鼠血清E2、P水平,以游标卡尺测量各组大鼠乳头高度、直径,并进行组间比较.结果 与空白组比较,模型组大鼠乳头高度及血清E2水平、E2/P明显升高,乳头直径明显增大,血清P水平明显降低,差异均有统计学意义(P＜0.01);与模型组比较,普通针刺组与针刺序贯组大鼠乳头高度及血清E2水平、E2/P明显降低,乳头直径明显缩小,血清P水平明显升高,差异均有统计学意义(P＜0.05或P＜0.01);针刺序贯组大鼠乳头高度及血清E2/P明显低于普通针刺组,乳头直径明显小于普通针刺组,血清P水平明显高于普通针刺组,2组比较差异均有统计学意义(P＜0.05或P＜0.01).结论 针刺序贯疗法能调节乳腺增生症模型大鼠的血清E2、P水平,降低或缩小大鼠乳头高度和直径;针刺序贯疗法治疗乳腺增生症的作用机制可能与其调节激素水平作用有关.

斑秃属于皮肤病中的一种,其发病呈逐年上升趋势,严重影响人们的身心健康.文章介绍纪峰副教授运用固本生发针法治疗斑秃的临床经验,纪峰副教授认为本病的发生与先后天之本及心神关系密切,治疗时重视固本护源,调养心神,标本兼顾,往往可取得显著的临床效果,降低其复发率.

阴阳五行学说是中医学的核心理论,贯穿在中医学理、法、方、药的各个层面.本文提炼《黄帝内经》《难经》等经典中关于阴阳五行指导中医分析病因、阐明病机、指导诊断、确立治法、处方遣药等方面的内容,发皇古义,融会新知,本文浅探中医阴阳五行诊疗体系中的病机诊断内容,以为临床提供参考.

纪峰副教授长期从事针灸对生殖内分泌调节的基础与临床研究.本文通过笔者跟师收集的病案浅谈纪峰副教授治疗乳腺增生病的临床经验.乳腺增生病的主要病机是肝郁痰凝、冲任失调.治疗上以疏肝理气、化痰散结、调理冲任为基本治法.纪峰副教授临床上多采用调周消癖法进行辨证施治,调周消癖法主要由针灸调周法、局部闪罐法和虚掌拍背法组成.现将一则验案报道如下:

带有中国传统文化特色的身心医学体系——中医心质学,它脱胎于中国传统文化与中医药学,根植于中华千年丰厚的文化宝库,同时又以中国传统文化和中医基础理论为根坻,以中医体质学、中医心理学、整体心理学、灵性心理学以及现代心理学等相关理论为指导,以中国传统文化对心质的观察总结为基本视角,研究人类心质特征、心质类型的生理及病理特点,分析心质疾病的产生与发展,运用心质理论指导疾病预防、治疗及养生的全新学科,中医心质学的提出是医学心理学和中国传统文化融合发展的重要体现和实际探索.本文就心质学的内涵和源流,心质学的三个维度包括心灵质、心识质、心意质的具体内容,中医心质学的概念、理论源泉及架构、优势及学术价值和心质的影响因素等进行了初步整理.

调气通腑法是纪峰创立的一套治疗便秘的联合疗法,主要由体针、耳穴贴压和走罐治疗组成.该文介绍调气通腑法的具体操作内容及治疗出口梗阻型便秘验案1则,旨在为该病的临床治疗提供参考依据.

围绝经期乳腺增生症发生率较高,严重影响妇女身心健康,其临床长期HRT治疗可能增加癌症风险,中医药治疗具有绿色、 安全、 方便的特点,文章总结纪峰副教授治疗围绝经期乳腺增生症的临证经验.纪峰副教授认为围绝经期乳腺增生症病机在于冲任失调,兼肝郁痰凝,重调周期、 调肝与病位辨经结合论治,运用调周消癖法治疗本病,疗效颇佳.

当今,经络腧穴学双语教学的关注焦点多在英文教学效果,而忽视育人思政.而育人视角下课程思政的融入可增强学生医学使命感及责任感,激发学生对祖国及中医事业的热爱之情,在专业教学中发挥重要的作用.文章对育人思政融入《经络腧穴学》双语教学的意义、途径及应用进行探讨,旨以提高本课程教学质量,培养符合我国现代针灸发展所需的专业化及国际化的综合型医学人才.

自古以来,"眦"之定位迥然相异,各执己说。现与之相关教科书尚无法明确指导定位。作者查阅历代文献及相关书籍,从"眦"之字形演变、古义探究、现代解剖及针灸专业相关论述等方面深入探讨,旨在明确"眦"之内涵及准确定位。

目的:探究艾灸足三里对自然衰老大鼠皮肤衰老的影响.方法:选取自然衰老大鼠连续足三里艾灸6个月,H&E和马松染色观察皮肤组织形态和纤维化,检测氧化指标SOD活力和MDA含量,qPCR检测皮肤中多种生长因子的表达,ELISA检测皮肤中雌二醇的含量,Western Blot检测皮肤胶原蛋白的变化.结果:与对照组比较,艾灸组能明显增加皮肤中多种生长因子的表达,增加胶原蛋白和雌二醇的含量,减少衰老带来的皮肤氧化.结论:艾灸能显著缓解老龄鼠的皮肤衰老.

Background: The aim of this study was to explore whether letrozole and high-fat diets (HFD) can induce obese insulin-resistant polycystic ovary syndrome (PCOS) with all reproductive and metabolic phenotypes in a rat model. Material/Methods: Twenty-four 3-week-old female Sprague-Dawley rats were randomized into 4 groups: control, Letrozole, HFD, and Letrozol+HFD. The PCOS model was induced by 12 weeks of Letrozole treatment (1 mg/kg p.o. dissolved in 0.5% CMC solutions once daily) and HFD. Ovarian morphology, estrous cyclicity, hormonal status, body weight, glucose and insulin tolerance, lipid profile, and insulin signaling pathway were investigated. Results: The rat model manifests anovulatory cycles and PCO morphology, increased body weight, elevated testosterone levels, abnormal glucose and lipid metabolism, and insulin resistance. The rat model also expresses significantly decreased phosphorylation of 6 essential signaling proteins - INSR, IRS, PI3K, AKT, ERK1, ERK2 - in the PI3K/AKT and MAPK/ERK pathways in the classic insulin-sensitive tissues (e.g., quadriceps femoris muscle, omentum majus, and liver), as well as non-classic target ovary tissues. Disrupted insulin signaling contributes to the decrease in insulin sensitivity and compensatory hyperinsulinemia in PCOS rats. Conclusions: Continuous administration of letrozole and high-fat diets can induce PCOS, metabolic phenotypes, and disrupted activation of the insulin signaling pathway.

子宫内膜过薄主要与肾精亏虚、冲任不调有关,故从周期出发,以调理冲任、补肾填精为原则,根据薄型子宫内膜不孕症患者的生理病理及周期特点进行针灸治疗,临床疗效显著.

纪峰副教授临证多年,运用“通乳三步法”治疗乳汁淤积.临床中结合乳汁淤积的病因病机,提出“明确诊断,治病宜早,以消为贵”的治疗思路.本文归纳了“通乳三步法”相关操作技术及要点,以期与同行交流.

我国古代认为时空是不可分割的,干支的建立是古人对时空模型化取象的典范,是古人实现“天人相应”的工具.对时间而言,“时、日、月、年”干支与中医学营卫一日出入、子午流注、24节气、五运六气等理论都有深刻的联系;对空间而言,干支方位模型是中医学九宫八风、因地制宜学说中重要的空间标度,对指导中医学基础理论的构建、诊断与治疗方面都有广泛的应用.

本文阐述了针刺周期疗法的中西医理论基础、形成过程,介绍了月经周期中月经期、经后期、经间期、经前期四个不同分期的治疗方法、取穴、操作及针刺周期疗法治疗月经病(月经不调、闭经、崩漏、痛经)的具体应用方法.

女性绝经前的特殊病理及生理内环境以“衰始阳明”为基点,女子“五七”“阳明脉衰”的表现之一是“面始焦”,即面部开始出现面色憔悴、无华甚至皱纹等衰老表现,可见女子皮肤衰老和阳明脉的盛衰关系密切.故从足阳明经脉的循行特点,阳明脉衰是皮肤衰老的先导,阳明脉衰是皮肤衰老的病理生理内环境,更年期是机体走向衰老的关键启动期,雌激素水平下降加速皮肤衰老和充阳明而实三阳,是“治未病”、延缓机体衰老重要环节的5个方面探讨女子“阳明脉衰”与皮肤衰老的病机及其防治的相关性.认为“阳明脉衰”是女子绝经前的主要病理生理特点,改善“阳明脉不足”是延缓女子皮肤衰老的治本措施,体现了中医治未病的思想.

虚拟现实(VR)是近年来兴起的一种基于计算机技术为主的现代高科技手段,并在医学领域中呈现其独特优势.经络腧穴学作为针灸推拿学专业学生的主干及基础课程,是学生掌握本专业其他理论和技能的基础和关键.课题组结合目前经络腧穴学教学改革及其抽象二维教学模式中面临的瓶颈,将VR技术应用于经络腧穴学的教学实践中,结果表明基于VR技术的经络腧穴学教学具有直观、高效、真实等优点.其最终旨在提高针灸推拿专业课程的教学质量,为学生后期的专业学习打下坚实的基础.

Objective To observe the effect of periodic acupoint catgut implantation on the quanity of estrogen E2 and progesterone P in rats model of Hyperplasia of mammary gland. Methods 32 Female non-pregnant SD Rats were randomly divided into normal control group, model control group, periodic acupoint catgut embedding group and common acupoint catgut embedding group.The treatment group was embedded 1 time in each sexual cycle, 1 times for a course, and a total of 3 sexual cycle. After the intervention, blood samples were drawn from the abdominal aorta, separate the serum, then test the quanity of E2 and P by using the electrochemical immunoluminometric. Results Compared with the model control group, serum E2 level of periodic acupoint catgut embedding group was significantly decreased, and the serum P level was significantly increased, and there were significant differences(P<0.01); The serum E2 level of the common acupoint catgut embedding group was significantly reduced, and the serum P level increased significantly, and there were significant differences(P<0.05). Compared with the common acupoint catgut embedding group, the decrease of serum E2 level and P level in the rats with periodic acupoint catgut embedding group was more obvious, and there was significant difference(P<0.05). Conclusion the periodic Catgut embedding method and the common acupoint catgut embedding method can inhibit and improve the hyperplasia of mammary gland, but the effect of the periodic acupoint catgut embedding method is better than the common acupoint catgut embedding method, which may be related to the regulation of serum sex hormone level.