目的 观察注射用血塞通(冻干)治疗视网膜中央静脉阻塞瘀血阻滞证的有效性和安全性.方法 采取多中心、随机、双盲、阳性药与安慰剂平行对照的临床对照试验方法,按照随机数字表法将患者分为试验组、阳性对照组和安慰剂组.试验组采用注射用血塞通(冻干)静脉滴注,阳性对照组采用复方血栓通胶囊口服,安慰剂组采用复方血栓通胶囊模拟剂口服.15 d为1个疗程,共计2个疗程.主要疗效评价指标:眼底血管荧光造影视网膜循环时间;次要疗效评价指标:最佳矫正视力(BCVA)、眼底出血面积、无灌注区面积、有无新生血管生成、中医证候等.结果 (1)视网膜循环时间3组比较,差异无统计学意义(P=0.5658);(2)3组间BCVA比较差异有统计学意义(P=0.002),试验组、阳性对照组分别与安慰剂比较,2组差异均有统计学意义(试验组P=0.001,阳性对照组P=0.003),试验组与阳性对照组疗效比较,差异无统计学意义(P=0.826);(3)中医证候疗效结果,3组间比较差异有统计学意义(P<0.001);试验组、阳性对照组分别与安慰剂比较,2组差异均有统计学意义(试验组P<0.001,阳性对照组P=0.006),试验组与阳性对照组疗效比较,差异无统计学意义(P>0.05);(4)眼底出血面积、无灌注区面积、有无新生血管生成方面,3组间比较差异无统计学意义.结论 注射用血塞通(冻干)可以改善视网膜中央静脉阻塞瘀血阻滞证患者视力及中医证候,临床使用安全,注射用血塞通(冻干)治疗视网膜中央静脉阻塞(瘀血阻滞证)具有较好的临床应用前景.

OBJECTIVE To verify the clinical efficacy and safety performance of the Thunder-fire moxibus-tion. according to medical technical operation scheme of traditional Chinese medicine clinical validation work re-quirements of Chinese Medicine Administration Bureau. METHODS A foresight, multicenter and self control clini-cal research project was designed, and a cooperative group was set up by Dongfang Hospital, Beijing Hospital of TCM and Dongzhimen Hospital. Each hospital with 30 dry eye cases was treated by Zhaoˊs thunder-fire moxibustion of Chongqing, once a day, 4 weeks treatment. Observed the objective indicators like the scores of clinical synptoms, tear film break-up time, schirmer test and cornea fluorescein staining, the statistical analysis was made at the end. ESULTS The effective rate of the thunder-fire moxibustion was 63%~75% in improving the dry feeling, foreign body sensation and asthenopia, while the effective rate was 38.9% in burning sensation and redness. CONCLU-SIONS To the dry-eye which was characterized by dry feeling, foreign body sensation and asthenopia, the therapeu-tic effect of thunder-fire moxibustion was obvious, while to the over evaporation dry-eye which was characterized by burning sensation and redness, the therapeutic effect was not significant.

To observe the clinical effect of aligned needling method in treating idiopathic blepharospasm.

目的清肝解毒汤治疗单纯疱疹病毒性角膜炎的疗效观察。方法将患者随机分为两组,对照组用阿昔洛韦滴眼液进行点眼;治疗组用阿昔洛韦滴眼液进行点眼的同时加用清肝解毒汤,观察两组临床疗效、眼部检查、自觉症状、治愈时间和复发率。结果治疗组在总有效率、后眼部检查积分、症状积分、平均治愈时间、复发率等方面均优于对照组。结论清肝解毒汤治疗单纯疱疹病毒性角膜炎疗效确切,能缩短疗程,降低复发率。

<正>1病例报告冯某,男,61岁,主因发现右眼视物不清十余天于2011年1月14日入院。患者因2003年4月诊断为Wegener肉芽肿并于外院行鼻部手术,2003年10月复发,再次行手术治疗,术后化疗6个月。现使用双氯芬酸钠缓释片控制,病情稳定。自诉半个月余前无明显诱因发现右眼视物不清,眼前如有白雾遮挡,伴有头部憋闷感,眼胀、眼涩不适等症状。入院

Objective To investigate the efficacy of orbicularis oculi-aligned acupuncture in treating idiopathic blepharospasm.Methods Seventy-eight patients with idiopathic blepharospasm were randomly allocated to a treatment group of 46 cases and a control group of 32 cases.The treatment group received orbicularis oculi-aligned acupuncture and the control group,medication.The therapeutic effects were compared between the two groups after 3 courses of treatment.Results The total efficacy rate was 93.5% in the treatment group and 75.0% in the control group;there was a statistically significant difference between the two groups(P0.05).Conclusion Orbicularis oculi-aligned acupuncture is a safe,highly effective and easy way to treat idiopathic blepharospasm.

<正>患者刘某,女,43岁,主因玻璃杯击伤右眼后视物不见1小时急诊于2007年12月25日10:30AM入院。眼科检查:视力右眼光感,左眼0.5,双眼矫正不提高。

目的对非糖尿病性及非视网膜血管性眼底病的黄斑拱环血管扩张患者进行临床分析。方法回顾总结43例荧光素眼底血管造影出现黄斑拱环血管扩张患者的临床资料。结果荧光素眼底血管造影检查有黄斑拱环血管扩张者43例中,伴有散在几个微血管瘤者3只眼;黄白色硬性渗出2只眼;黄斑区有透见高荧光1只眼;眼底动脉硬化12只眼;造影下拱环血管结构破坏或欠清、环沿不规整6只眼;有玻璃膜疣5只眼,随访发现即使造影时视力正常,以后也有可能出现视功能下降。结论对于非糖尿病性及非视网膜血管性眼底病而呈现的黄斑拱环血管扩张、尤其是视功能正常者也要重视临床的追踪与随访。

Diabetic macular edema is the primary cause for the vision loss of patients with diabetes.People have made a lot of relative clinical studies.In this paper,the author reviews the definition,classification,pathogenesis and the treatment of different drugs in recent years.Conclusion: With the progress made in clinical research of different drugs diabetic macular edema can be treated in time.Thereby the eyesight of patients with diabetes can be protected.

患者 男,8岁,因双眼视力低下6个月于2007年3月3日入我院就诊.患儿曾在当地多家医院多次头颅CT及MRI检查和基因检测,后来京就诊为球后视神经炎,经激素大剂量冲击治疗,效果不明显.

Objective To observe the curative effect of acupuncture mainly in Taichong (LR3) and Guangming (GB37) on asthenopia . Method To divide randomly 60 cases of asthenopia into the acupuncture group (n=30, treated with needling in LR3 and GB37 mainly) and the control group (n=30, treated with New V Rohto Eye Drops), observe and compare the integral changes of eye symptoms and curative effects. Result After the treatment the symptom integrals of two groups decreased obviously with a statistic significance (P0.01). The total effective rate of the acupuncture group was 93.3 % which was higher than that of the control group. Conclusion Acupuncture with the effect of dredging meridians and orifices in Yuan and Luo acupoints was effective, safe and convenient for treating asthenopia.

对于闭角型青光眼合并白内障患者,是先行抗青光眼手术,还是先行白内障摘除手术,或者做青光眼白内障联合术,在眼科学界一直有争论,各家观点不一.我们于1999年起采用超声乳化白内障吸出术治疗闭角型青光眼合并白内障患者,取得满意结果.

脱髓鞘疾病是神经系统的一类重要疾病,基本病理特征是中枢神经系统(CNS)白质神经纤维的原发性脱髓鞘.常累及视神经,造成视功能障碍的脱髓鞘疾病主要有视神经脊髓炎(Devic病)和多发性硬化(MS).现将临床所遇资料完整的该两种脱髓鞘疾病做一小结分析.

糖尿病性视网膜病变(diabetic retinopathy,DR)是糖尿病的严重并发症,我们采用激光光凝治疗的同时给予中药六味地黄丸治疗该病,疗效较好,报道如下.

OBJECTIVE To observe effect of traditional Chinese medicine tuichizhiyang(退赤止痒) decoction on treatment of vernal conjunctivitis. METHODS One hundred and fifty five patients divided into observed groups and control group. The patients were treated with tuichizhiyang decoction combined with eyedrop containing dexamethasone and kanamycin in the observed group. The patients were treated only with eyedrop containing dexamethasone and kanamycin in the control group. At 2 weeks and 4 weeks effect of treatment was recorded and ratio of recurrence was compared between two groups. RESULTS There was not significant difference at 2 weeks (P>0.05). Effective ratio was higher in the observed group than in the control group (P<0.05). In period of follow-up ratio of recurrence was lower in the observed group than in the control group(P<0.01). CONCLUSIONS Traditional Chinese medicine tuichizhiyang decoction could be available and it could reduce ratio of recurrence in treatment of vernal conjunctivitis.

单疱病毒性角膜炎是由单纯疱疹病毒Ⅰ型感染所致的眼病,是眼科多发病、常见病之一.本病症状严重,病程迁延,容易复发.本病治疗方法甚多,如碘苷、环孢苷、阿糖腺苷、三氟胸腺嘧啶、无环鸟苷、干扰素、转移因子及冷冻、烧灼、激光、角膜移植等;中药亦有板蓝根、熊胆、珍珠层粉、紫丁香叶、中医中药辨证施治等,各有疗效.