目的 分析克拉玛依市艾滋病病人的病毒载量(VL)和CD4+T巴细胞水平,了解本地艾滋病病毒感染者(HIV)和艾滋病患者(AIDS)的治疗现状和病情进展情况.方法 采用淋巴细胞计数仪和病毒载量检测仪对患者的静脉血进行CD4+T淋巴细胞和VL检测.结果 随治疗时间的延长,290例AIDS患者CD4+细胞＜200个/μL的构成比越低(x2=5.11,P=0.078),CD4+细胞＞350个/μL的构成比越高(x2=11.55,P=0.003),VL＜20 copy/mL的构成比越高(x2=66.33,P＜0.001),VL≥105 copy/mL的构成比越低(x2=13.37,P=0.001),且VL值随CD4+细胞计数的增加呈降低趋势,表现为负相关;新发未治疗100例HIV感染者首次CD4+细胞平均计数为355.89±197.29个/μL,其中有18.00％的HIV感染者CD4+细胞＜200个/μL,未能及时开展治疗.结论 AIDS患者通过一定时间的抗病毒治疗后体内的免疫功能增强,病毒的抑制效果较好,但该地区还存在少部分HIV患者,未能及时进行抗病毒治疗,应做到早发现、早检测,确保最佳治疗时机.

目的 了解克拉玛依市现存活HIV感染者的高危行为史及社会支持状况,为针对性预防HIV传播及开展病例管理提供依据.方法 对＞18岁的HIV-1感染者开展问卷调查,调查内容包括一般人口学信息、高危行为史及社会支持状况.结果 共调查HIV-1感染者201例,年龄以＜45岁青壮年为主,占54.23％;以维吾尔族和汉族为主,分别占47.76％、43.28％.91.04％的感染者确诊前从未进行过HIV-1检测,64.68％的感染者在确诊前与性伴发生性行为时未使用安全套.65.17％将阳性检测结果告知他人,其中告诉配偶/伴侣的占52.67％,告诉父母的占45.80％.180(89.55％)例认为确诊对自己的婚姻状况不会产生影响;41例(20.40％)在确诊后与配偶/伴侣发生过性行为.结论 克拉玛依市HIV感染者确诊前高危性行为发生率高,HIV检测率低,应通过提高当地HIV检测率、降低高危性行为发生率来阻止当地疫情的进一步上升.

Objective:To study the effect of hydrogen sulfide (H 2S) on the behavior and brain edema of rats with traumatic brain injury (TBI). Methods:Male SD rats were randomly divided into Sham group, TBI group, TBI+ vehicle group and TBI+ NaHS group. The rat model of traumatic brain injury was prepared by using craniocerebral injury impingement device. The motor function was evaluated by wire-grip test and rota-rod test, and the spatial cognitive function was evaluated by Morris water maze test. The water content of rat brain tissue was determined by wet-dry weight method, and the pathological changes were observed by hematoxylin and eosin (HE) staining.Results:The scores of wire-grip test in TBI+ NaHS group was (1.95±0.21), respectively lower than Sham group(4.12±0.19, P<0.05), and respectively higher than TBI group (1.13±0.23) and TBI+ vehicle group (1.34±0.42, F=120.980, P<0.05); The drop time of rota-rod test in TBI+ NaHS group was (148±27) s, respectively lower than Sham group [(276±18) s, P<0.05], and respectively higher than TBI group [(72±14) s] and TBI+ vehicle group [(78±24) s, F=98.552, P<0.05]; The escape time of water maze test in TBI+ NaHS group was (51±5) s, respectively higher than Sham group [(36±7) s, P<0.05], and respectively lower than TBI group [(71±3) s] and TBI+ vehicle group [(82±5) s, F=77.903, P<0.05]; The pass frequency of water maze test in TBI+ NaHS group was (8±2) times, respectively lower than Sham group [(13±2) times, P<0.05], and respectively higher than TBI group [(4±1) times] and TBI+ vehicle group [(5±1) times, F=32.672, P<0.05]; The percentage of brain water content in TBI+ NaHS group was (72±3)%, respectively higher than Sham group [(68±5)%, P<0.05], and respectively lower than TBI group(86±4)times and TBI+ vehicle group [(84±3) times, F=26.551, P<0.05]. Compared with Sham group, the brain tissue of rats in TBI group and TBI+ vehicle group showed serious pathological changes, and the pathological changes of rats in TBI+ NaHS group were improved. Conclusion:Hydrogen sulfide may imprve the motor and spatial memory defects and brain edema caused by traumatic craniocerebral injury.

Objective:To investigate the relationship between the origin of vertebral artery and the height of transverse foramen of cervical vertebra using three-dimensional CT angiography (CTA).Methods:The clinical data of 480 patients who underwent head, neck and upper chest CTA examinations from March 2017 to March 2019 at Department of Neurosurgery, the Second Hospital of Hebei Medical University were retrospectively analyzed. The images were transferred to the image post-processing workstation for bone and vascular reconstruction, and the origin and course of bilateral vertebral arteries and the height of the vertebral arteries entering the cervical vertebrae transverse foramen were documented. Patients with normal origin of the right vertebral artery were divided into groups C 4, C 5, and C 6 according to the height of vertebral artery entering transverse foramen of cervical vertebra. Ten cases were randomly selected from each group to measure the distance from the origin of right vertebral artery to the origin of right common carotid artery (L 1) and to the right thyroid cervical trunk (L 2). We calculated the relative position of the origin of vertebral artery with L1/(L 1+ L 2)×100%. Results:Among 480 patients, 457 cases (95.2%) had normal origins of bilateral vertebral arteries which were from the subclavian artery, and the other 23 cases (4.8%) had abnormal origins. Among them, the left vertebral artery originated from the aortic arch in 19 cases, and left vertebral artery originated from the left external carotid artery in 1 case; the right vertebral artery originated from the right common carotid artery in 3 cases, all of which were complicated with aberrant right subclavian artery. Among the 480 patients, 405 cases (84.4%) had bilateral vertebral arteries entering the C 6 transverse foramen. The remaining 75 (15.6%) had vertebral arteries entering the cervical transverse foramen with abnormal height, which was observed on the left side in 34 cases (left vertebral arteries entering transverse foramen of C 3, C 4, C 5, C 7 in 1 case, 4 cases, 24 cases and 4 cases respectively, and directly entering the foramen magnum in 1 case) and on the right side in 41 cases (right vertebral artery entering C 3, C 4 and C 5 in 1 case, 14 cases, 26 cases respectively). The height of vertebral artery entering transverse foramen of cervical vertebra was mostly abnormal when the origin of left vertebral artery was abnormal. In patients with abnormal vertebral artery origin, the left vertebral artery originating from the aortic arch accounted for the highest proportion (19/20), and most of the vertebral arteries entered the transverse foramen of cervical vertebra with abnormal height (18/19). The right vertebral artery originating from the right common carotid artery were complicated with aberrant right subclavian artery (3/3), and the height of vertebral artery entering transverse foramen of cervical vertebra was abnormal (3/3). In patients with normal vertebral artery origin, 96.7% (445/460) of left vertebral artery entered transverse foramen of cervical vertebra with normal height, and 92.0% (439/477) of the right vertebral artery entered transverse foramen of cervical vertebra with normal height. Comparison of patients with normal right vertebral artery origin in the 3 groups showed statistically significant differences in the relative position of the vertebral artery origin (C 4 group: 24.3±2.1 %, C 5 group: 47.9±6.6 %, and C 6 group: 77.7±1.7 %, H=20.178, P<0.001). Conclusions:In case of abnormal origins of vertebral arteries, the heights of vertebral arteries at the transverse foramen of cervical vertebra are mostly abnormal. When the relative position of origin of right vertebral artery is closer to the right common carotid artery, the height of right vertebral artery at the transverse foramen of cervical vertebra seems higher. When the relative origin of right vertebral artery is closer to the right thyroid cervical trunk, the height of right vertebral artery at the transverse foramen of cervical vertebra seems lower.

目的 了解2008-2015年新疆克拉玛依市接受艾滋病免费抗病毒治疗病人入组时的流行病学特征,为进一步实施艾滋病免费抗病毒治疗工作提供依据. 方法 利用国家艾滋病综合防治信息系统抗病毒治疗管理数据库中收集的2008-2015年接受艾滋病抗病毒治疗病人的基本情况表及随访表,建立EXCEL数据库,并使用SPSS 17.0软件进行统计分析. 结果 截止2015年12月31日,克拉玛依市接受艾滋病抗病毒治疗累计267例,其中男性占63.3％、女性占36.7％,男女性别比1.72∶1,平均年龄(43.00± 11.58)岁,以20～ 49岁青壮年为主(占78.3％),30岁以下年龄组呈现上升趋势(x2=21.70,P＜0.05);以性传播为主、占68.9％,其中异性性传播占53.2％、同性性传播占15.7％,各年新入组病例中,同性性传播比例呈逐年增长趋势(x2=20.65,P＜0.05);发现来源以医疗机构(其他就诊者、术前、孕产期和性病门诊病人检测)为主、占55.0％;治疗前基线CD4+T淋巴细胞平均值(315.29±201.36)个/μl;治疗前病人的临床分期,2008-2015年Ⅰ期所占比例呈现逐年上升趋势,Ⅲ期和Ⅳ期所占比例呈现逐年下降趋势(x2=124.03,P＜0.01). 结论 克拉玛依市近几年随着治疗标准的放宽和覆盖面的扩大,治疗人数逐年有所增加,但艾滋病病毒感染者/病人接受抗病毒治疗的时机仍较晚,因此应采取更科学、有效的措施及早发现病人,并及时纳入抗病毒治疗管理.

OBJECTIVE To explore the influencing factors for intracranial infections in patients after craniotomy and investigate the distribution of pathogens.METHODS A total of 1 126 patients who received the craniotomy in neurosurgery department of the hospital from Apr 2012 to Jan 2016 were enrolled in the study,the clinical data of the patients were retrospectively analyzed,the univariate analysis and multivariate logistic analysis were performed for the influencing factors for the postoperative infections,and the pathogens that were isolated from cerebrospinal fluid specimens of the patients with the infections were observed.RESULTS Of the 1 126 patients who received the craniotomy,totally 78 patients had postoperative intracranial infections,with the infection rate 6.93％.The incidence of the postoperative intracranial infection was not associated with the age,gender,body mass index,types of surgery,number of times of surgery or complication with underlying diseases (P＞0.05).The related factors for the postoperative intracranial infections in the patients undergoing the craniotomy included the subcutaneous drainage,leakage of cerebrospinal fluid,ASA,operation duration and postoperative albumin level less than 35 g/L.A total of 78 strains of pathogens were isolated from the cerebrospinal fluid specimens of the 78 patients with the intracranial infections,of which 47 (60.26 ％) were gram-positive bacteria,24 (30.77 ％) were gram-negative bacteria,and 7 (8.97％) were fungi.CONCLUSION Subcutaneous drainage indwelling,leakage of cerebrospinal fluid and operation duration are the related influencing factors for the postoperative intracranial infections in the patients undergoing the craniotomy.It is of great significance to take targeted prevention measures aiming at the influencing factors so as to reduce the incidence of the postoperative infections.

目的 观察丁苯酞注射液联合法舒地尔注射液治疗脑动脉瘤栓塞术后脑血管痉挛的临床疗效及安全性.方法 将92例脑动脉瘤栓塞术后脑血管痉挛患者随机分为对照组46例和试验组46例.对照组予以抗感染、镇静止咳、降颅内压、脱水等对症治疗;试验组在对照组治疗的基础上,予以丁苯酞每次100mL,qd,静脉滴注,持续治疗7d+法舒地尔每次30 mg,tid,微泵持续静脉输注.2组患者均持续治疗14 d.比较2组患者的临床疗效,血清基质金属蛋白酶-2(MMP-2)、MMP-9和Caspase-3,以及药物不良反应的发生情况.结果 治疗后,试验组和对照组的总有效率分另为91.30％(42例/46例)和76.09％ (35例/46例),差异有统计学意义(P＜0.05).治疗后,试验组和对照组的血清MMP-2分别为(21.23±2.59)和(35.75±4.41)μg· L-1,MMP-9分别为(12.75±1.46)和(19.11±2.47) μmol·L-1,Caspase-3分别为(206.15±25.64)和(305.64±40.01) μg·L-1,差异均有统计学意义(均P＜0.05).2组患者的药物不良反应主要有颜面潮红、低血压和恶心呕吐.试验组和对照组的总药物不良反应发生率分别为8.70％和17.39％,差异无统计学意义(P＞0.05).结论丁苯酞注射液联合法舒地尔注射液治疗脑动脉瘤栓塞术后脑血管痉挛的临床疗效确切,其能显著下调患者血清中MMP-2、MMP-9和Caspase-3的水平,且不增加药物不良反应的发生率.

目的 分析健康教育在新发传染病中的临床效果.方法 选取2015年4月～2017年8月本疾控中心辖区内的1000名居民作为研究对象,于2016年5～8月对居民展开健康教育干预,比较健康教育实施前后居民的健康知识知晓情况、健康行为控制情况及传染病发生率.结果 健康教育实施前,1000名居民的健康知识知晓评分是(73.2±3.5)分,健康教育实施后是(91.3±5.6)分,健康教育实施后评分显著高于健康教育实施前,差异有统计学意义(P＜0.05).健康教育实施后,居民吸烟与饮酒、食盐摄入过量率明显低于健康教育实施前,参与体育锻炼的概率显著高于健康教育实施前,传染病发生率显著低于健康教育实施前,差异有统计学意义(P＜0.05).结论 健康教育在新发传染病治疗中能发挥出有效作用,对于新发传染病医务人员应加大防控力度,提高防范水平.

实验室质量管理是疾控机构质量管理体系的重要组成部分,是实验室工作的关键环节,而质量体系的建立是实验室管理的基础.文章从质量管理理论的"人、机、料、法、环"五大因素方面,讨论了全面提升基层疾控机构实验室质量管理,保证实验室质量体系有效运行的主要工作内容.

[Objective] To discuss the clinical features and surgical outcome of cervical ossification of the posterior longitudinal ligament (OPLL) associated with cervical disc herniation (CDH).[Methods] Between January 2011 and January 2014,78 patients with radiologically proven OPLL were enrolled in this study.Of them,19 patients were complicated with CDH,while the remaining 59 patients proved no associated with CDH.Amomg the 19 patients with OPLL and CDH,14 patients who had CDH within the segments of OPLL received anterior corpectomy and fusion (ACCF),whereas 5 patients with CDH adjacent to OPLL segment were treated with ACCF combined with anterior discectomy and fusion (ACDF).The neurological function,occupying ratio (OR),cord flattening rate and cervical lordosis were measured for evaluation of clinical outcome.[Results] Compared with the patients without CDH,the illness course of the patients combined with CDH progressed more quickly (P＜0.05),which usually flared up with the CDH as the major compression factor.The 19 patients were followed up for an average of 24 months.The mean JOA score increased from 9.16 preoperatively to 13.84 at final follow-up (P＜0.05)with an improvement rate of 61.55％.Additionally the mean OR decreased from 38.95％ preoperatively to 8.47％ postoperatively (P＜0.05),the cervical lordosis increased from 9.34 degrees preoperatively to 15.19 degrees at the last follow-up (P＜0.05),as well as the cord flattening rate increased from 26％ preoperatively to 49％ at the last follow-up (P ＜0.05).Cerebrospinal fluid (CSF) leakage was found in 2 patients and C5 palsy occurred in 1 patient,but both of them recovered spontaneously after conservative treatment.[Conclusion] The clinical symptoms of the patients with OPLL may suddenly appear or aggravate due to CDH.Based on the location relationship between OPLL and CDH,the proper anterior surgical decompressions do achieve satisfactory outcomes.

目的 了解本市各级医疗机构消毒效果的状况,为指导医院消毒工作,预防并控制医院内感染,对医疗机构消毒效果做出科学评价提供依据.方法 参照WS/T 367-2012版《医疗机构消毒技术规范》和《医院消毒卫生标准》(GB 15982-2012)的方法和要求,2013-2015年笔者分别对14家医疗机构的消毒效果进行了监测.监测场所包括:医疗机构换药室、注射室、处置室、手术间;监测项目为菌落总数检测:空气消毒监测、监测场所无菌区台面、门把手及护理人员手的消毒监测、使用中的消毒剂含量监测、压力蒸汽灭菌器、器械监测和医疗机构排放污水监测.结果 3年总合格率为88％,2013-2015年合格率依次为79％、90％和96％.消毒质量呈现逐年升高的趋势.结论 大石桥市医疗机构消毒效果总体来看合格率逐年升高,只要加强消毒工作的监督和管理,切实把消毒工作落到实处,医疗机构的内部感染几率会大大减小.

目的 对比分析经皮椎体成形术(PVP)与经皮椎体后凸成形术(PKP)治疗重度骨质疏松性椎体压缩骨折(OVCF)的临床疗效及安全性.方法 回顾性分析河北医科大学第三医院脊柱外科2012年9月至2015年9月行PVP或PKP治疗的重度OVCF 57例,根据手术方式不同分为PVP组(n=31)和PKP组(n=26).随访并比较两组患者术前、术后1 d及末次随访时伤椎前缘高度、局部Cobb角、疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)的变化以及骨水泥渗漏、邻近椎体骨折等术后并发症发生情况.结果 所有手术均顺利完成,57例患者均获完整随访,随访时间12~20个月,平均(16.1±2.3)个月.PVP组患者的手术时间为(30±3)min,少于PKP组的(37±4)min,差异有统计学意义(t=7.413,P<0.05).两组患者术后1 d及末次随访时VAS、ODI评分及局部Cobb角较术前均有改善,差异有统计学意义(PVP组:F=260.639,F=276.357,F=20.783,P<0.01;PKP组:F=162.701,F=196.772,F=83.591,P<0.01).PKP组患者术后1 d及末次随访时伤椎前缘高度较术前均有改善,差异有统计学意义(F=22.084,P<0.01),PVP组术后伤椎前缘高度与术前相比无统计学差异.两组间术后1 d及末次随访时VAS、ODI评分比较,无统计学差异.PKP组术后伤椎前缘高度及局部Cobb角改善均优于PVP组,差异有统计学意义(P<0.05).术中发生骨水泥渗漏15例(26.3%),无肺栓塞、脊髓神经损伤发生.随访期间共5例(8.8%)患者继发邻近椎体骨折.两组骨水泥渗漏率及邻近椎体骨折发生率无统计学差异.结论 对于重度骨质疏松性椎体压缩骨折的治疗,PVP与PKP均可显著缓解患者疼痛症状;PKP具有较好的复位和矫正后凸畸形的效果,但手术时间较长;PKP在骨水泥渗漏率、邻近椎体骨折发生率上相对于PVP未表现出明显的优越性.

Objective To investigate the value of intraoperative O-arm navigation in posterior hemivertebra resection for treatment of congenital kyphoscoliosis caused by fully segmented hemivertebr. Methods From January 2014 to March 2015, a total of 14 patients with congenital kyphoscoliosis caused by fully-segmented hemivertebra who had undergone hemivertebra resection surgery at the Third Hospital of Hebei Medical University were reviewed retrospectively. There were 5 males and 9 females with an average of 11. 9 years (ranged from 9 to 15 years). Among them, the hemivertebra were located at T9, L2 in each 1 patients, T10 , L1 in each 2 patients, T12 in 3 patients, T11 in 5 patients. Full-length standing radiographs were taken before surgery. The Cobb angle in the coronal and sagittal plane were measured and analyzed. All pedicle screws insertion was performed guided by intraoperative O-arm navigation. According to the comparison of intraoperative O-arm navigation in three-dimensional reconstruction of the hemivertebra, the scope of hemivertebra resection could be determined, and then individualized, thoroughly and effectively resected the hemivertebra. The screw position was observed by O-arm scan in operation and CT scan after surgery. And the pre-and post-operative changes of the Cobbs angle were analyzed in order to evaluate the correction rate of scoliosis and kyphosis. Results All the 120 screws for 14 patients were inserted exactly. The surgery time was (195. 4 ± 17. 4) min and blood loss was (611. 9 ± 173. 0) mL. All the patients were followed up from 3 to 15 months(average 9. 6 months). Scoliosis angle was corrected from 62. 8° ± 15. 8° to 10. 9° ± 5. 3° with a correction rate of 83. 34% ± 6. 08%. At the last follow-up, the scoliosis angle was 12. 1° ± 4. 8° with no significant loss of correction. Kyphosis angle was corrected from 57. 5° ± 15. 5° to 17. 0° ± 6. 6° with a correction rate of 70. 66% ± 6. 79%. At the last follow-up, the kyphosis angle was 17. 9° ± 7. 0° with no significant loss of correction. They were compared pre- and post-operative respectively, with significant differences(all P values < 0. 01). However, there were no significant differences between postoperative and the final follow-up(all P values >0. 05). No implants failure and correction lost were found during the follow-up. Conclusions In posterior approach hemivertebra resection for congenital kypho scoliosis patients caused by fully segmented hemivertebr, the use of intraoperative O-arm navigation can make screws insertion more accurate and safe. And resection of the hemivertebr is more accurate. In this way, it can reduce the complications and improve the safety of operation.

目的 应用离子色谱法测定生活饮用水中痕量二氯乙酸(DCAA)和三氯乙酸(TCAA).方法 根据离子色谱法原理,先将水样经0.2 μm微孔滤膜过滤,在仪器最佳工作条件下,测定阴离子的出峰保留时间及峰面积,以峰面积绘制离子浓度标准曲线.结果 线性范围0.02 ～ 0.60 mg/L;回归方程相关系数均在0.999 8 ～ 0.999 9,线性关系良好;将产生3倍于噪音水平的信号所代表的待测组分的最小浓度计算检出限,二氯乙酸为0.5 μg/L,三氯乙酸为5.0 μg/L;二氯乙酸0.02 ～ 0.30 mg/L和三氯乙酸0.04～ 0.60 mg/L浓度范围检测的RSD％在3.10％～4.90％,曲线相关性0.999 8 ～0.999 9,加标回收率均在85.00％～ 109.00％.结论 建立了用离子色谱法直接进样,电导检测饮用水中要求测定中的二氯乙酸、三氯乙酸含量的方法.

背景:O型臂导航系统是目前最先进的导航技术,可短时间内获得较高质量的术中三维CT图像,但其应用于脊柱外科时间尚短,应用价值需要进一步研究.目的:初步探讨O型臂导航系统在青少年特发性脊柱侧凸矫形内固定术中的应用价值.方法:回顾性分析2013年1月至2014年12月行脊柱后路侧凸矫形内固定术的青少年特发性脊柱侧凸患者42例,男7例,女35例.其中术中应用O型臂导航指导螺钉植入19例为O型臂导航组,依靠C型臂X线机透视和术者经验植入螺钉23例为C型臂引导组.分别记录两组患者的手术时间、置钉时间、术中出血量以及并发症发生情况;通过CT扫描对椎弓根螺钉位置进行分级,采用Richter方法计算两组的置钉优良率,术后通过全脊柱正侧位X线片评价矫形效果.结果:42例患者均顺利完成手术,两组患者的性别、年龄、累及节段、术前Cobb角等一般资料无统计学差异(P＞0.05).O型臂导航组患者上胸椎(T1～T4)、中胸椎(T5～T8)的置钉优良率为94.4％和95.6％,与C型臂引导组的78.9％和85.4％相比有统计学差异(P＜0.05).O型臂导航组下胸椎(T9～T12)以及腰椎(L1～L5)的置钉优良率为94.7％和95.4％,略高于C型臂引导组的88.2％和92.1％,相比无统计学差异(P＞0.05).O型臂导航组患者置钉时间为(75±20)min,显著低于C型臂引导组的(93±18)min(P＜0.05).两组手术时间、术中出血量比较无统计学差异(P＞0.05).所有患者均获得12～19个月,平均(16.5±2.1)个月的随访.两组术后1周及末次随访时主弯Cobb角均较术前显著改善(P＜0.05);术后1周与末次随访比较无统计学差异(P＞0.05).两组患者末次随访时Cobb角矫正率比较无统计学差异(P＞0.05).结论:O型臂导航技术应用于青少年特发性脊柱侧凸的手术治疗中可提高胸腰椎椎弓根螺钉植入的准确性和安全性,及时发现危险螺钉并重置,保障手术安全,近期矫形疗效确切.

目的：研究急性颈髓损伤后早期应用亚低温治疗的效果，及其对并发症发生率的影响。方法将急性颈髓损伤患者60例分为研究组和对照组，每组30例，研究组均在伤后8 h内实施亚低温治疗，持续72 h后复温；对照组采用一般性降温措施，其余治疗相同；分别于伤后12 h、6周、6个月、12个月采用美国脊髓损伤协会感觉和运动修正评分（AIS）对患者进行评估，出院时统计患者并发症发生率。结果研究组AIS评分改进显著（ P ＜0．05），并发症率与对照组比较差异无统计学意义（ P ＞0．05）。结论早期应用亚低温治疗急性颈髓损伤可以改善患者的预后，减少致残率，提高生存质量，为急性脊髓损伤的临床治疗提供一种新的途径。

目的 了解晋江市游泳场所水质状况,及时发现和处理存在的健康危害因素,保证游泳者身体健康.方法 按GB 9667-1996《游泳场所卫生标准》对全市游泳场所进行卫生检测.结果 2012-2013年共抽检样本246份,合格率53.7％;各指标合格率:pH值96.7％、浑浊度100.0％、尿素74.8％、游离性余氯80.5％、细菌总数94.3％和总大肠菌群100.0％;4类场所合格率:专业健身场所游泳池70.8％、五星级酒店游泳池70.0％、普通酒店游泳池40.5％和小区游泳池24.2％.结论 晋江市游泳场所水质合格率总体偏低,应加强普通酒店游泳场所及小区游泳池的卫生监管力度.

Objective:To investigate the effect of clinical nursing pathway in perioperative nursing care of patients with tongue cancer . Methods:38 tongue cancer patients who received oral and maxillofacial surgery in our hospital were randomly divided into the experimental group and the control group(19 cases in each group).The conventional treatment and nursing care was used in the control group and the treatment and nursing care was given to the patients according to clinical nursing pathway and the systematic rehabilitation training on tongue function was provided for the patients in the experimental group .The language,chewing,swallowing function recovery and satisfac-tion of the postoperative patients ,hospitalization time and cost were compared between the two groups .Results:The language,chewing func-tion and satisfaction of the postoperative patients were much better in the experimental group than the control group (P<0.05);the hospi-talization time and cost was significantly shorter and lower in the experimental group than the control group (P<0.05).Conclusion:The nursing intervention can significantly improve the language and masticatory function recovery in postoperative patients with tongue cancer , it can also improve the quality of life of the patients ,shorten and reduce hospitalization time and costs ,improve patient satisfaction and en-hance their health awareness .

为准确控制下泄流量，在更换闸门开度测量设备后应对工作闸门开度仪计量数据进行率定校正，复核无误后供水库调度管理人员使用。本文总结了克孜尔水库深孔泄洪排砂涵洞弧形工作闸门开度率定工作，认为闸门开度率定工作是一项细致而严谨的工作，要求工作人员紧密配合，服从统一调度，精准操作，遇到设备故障时要科学处理，确保率定各项工作有序开展。该方法及结果可为大型水利工程技术管理工作、设备研发提供借鉴或参考。

目的：评估弥漫性轴索损伤患者亚低温治疗中血流动力学变化和预后。方法选择弥漫性轴索损伤患者60例，分为对照组与治疗组。对照组30例，采用常规治疗；治疗组30例，采用常规治疗加亚低温治疗。治疗过程中应用TCD监测脑血流动力学及颅内压监护仪监测颅内压，6个月后行GOS评分判断预后。结果治疗组中脑血流平均血流速度、收缩期血流速度及搏动指数在亚低温治疗3 d后与对照组相比明显改善（ P ＜0．05）。治疗组在3 d后颅内压明显低于对照组（ P ＜0．05）。6个月预后治疗组明显优于对照组（ P ＜0．05）。结论亚低温能改善弥漫性轴索损伤后的脑血流动力学变化，降低颅内压，改善弥漫性轴索损伤患者的预后。