BACKGROUND:Intravenous therapy involves high-volume, invasive procedures that are inherently associated with patient discomfort and distress. When not managed optimally, such procedures can directly impact treatment efficacy and carry risks of severe complications. Intravenous therapy quality monitoring is essential for patient safety, yet standardized, practical tools for hospital-wide audits remain a critical gap. OBJECTIVE:This study aimed to develop and refine a practical, electronic quality assessment tool for hospital-wide intravenous therapy surveillance, and to evaluate its feasibility in clinical practice. This is Phase I of a larger project; Phase II will apply the tool to identify outcome gaps and drive improvement. METHODS:A multidisciplinary team developed the initial Hospital Intravenous Therapy Quality Assessment Tool (HIT-QAT) based on international and national standards. The tool underwent 14 iterative refinement cycles through hospital-wide cross-sectional surveys from June 2016 to May 2023. Each cycle involved: pilot testing, standardized auditor training, full-scale audit, data analysis, feedback sessions, and tool revision. Feasibility metrics included audit completion time, data completeness, and user acceptance. RESULTS:The finalized HIT-QAT structure comprises seven sections: Introduction, Infusion Status Basics, Medication Usage, Vascular Access Device (VAD) Selection, VAD Insertion & Management (Butterfly devices, Peripheral intravenous catheter (PIVC), Midline catheter, CVC, PICC, PORT, Other devices), Infusion Device Usage, Instructions. HIT-QAT is an electronic, mobile-accessible survey with automated skip logic. Across 14 audits conducted from 2016 to 2023, A total of 22,789 VADs were assessed by 67-76 trained audit liaisons per cycle. All audit liaisons completed a standardized 1-h training with zero resistance. CONCLUSION:The HIT-QAT is a feasible, practical, and efficient electronic tool for hospital-wide intravenous therapy quality assessment. This paper reports Phase I: tool design, refinement, and feasibility testing. Future studies (Phase II) will apply the tool to systematically identify practice deficiencies, track outcomes, and evaluate quality improvement interventions.

INTRODUCTION:Colonic anastomotic leak (CAL) represents one of the most critical complications following gastrointestinal surgery, inducing severe intra-abdominal infections, adhesion formation and persistently high mortality rates. This complication imposes a substantial socioeconomic and healthcare burden. OBJECTIVES:To address this challenge, cold atmospheric plasma (CAP)-loaded hydrogel was developed for intraperitoneal delivery of reactive species to anastomotic sites. METHODS:An anastomotic leak (AL) model was established in SD rats via surgical intervention. For in vitro studies, apoptosis was induced in HCT116 cells by treatment with TNF-α. Apoptosis was assessed using flow cytometry and Western blotting. Inflammatory cytokine levels were measured by enzyme-linked immunosorbent assay (ELISA). Histological changes were evaluated via immunofluorescence staining and immunohistochemistry. RESULTS:The cold atmospheric plasma-activated hydrogel (Hyd@CAP) gradually formed effective coverage over the anastomotic sites, enabling sustained release reactive oxygen and nitrogen species (RONS). These reactive species collectively exerted multifunctional effects including antimicrobial, anti-inflammatory and tissue-reparative activities. Our research demonstrated consistent adhesive stability at anastomotic sites and significant reduction in adhesion scores. Transcriptomic analysis of anastomotic tissues revealed that Hyd@CAP accelerated regeneration and proliferation of intestinal epithelial cells by releasing RONS that further activated the mTOR signaling pathway, thereby exerting antimicrobial, anti-inflammatory and tissue-reparative effects. CONCLUSION:Hyd@CAP represents an emerging therapeutic strategy with potential applications in the management of AL following gastrointestinal surgery. Its efficacy has been preliminarily validated in a rat model of CAL, suggesting potential for early-phase clinical translation and possible extension to anastomotic repair throughout the entire gastrointestinal tract.

Esophageal cancer (EC) patients undergoing concurrent chemoradiotherapy (CCRT) often face significant psychological distress, impaired quality of life (QoL), and poor nutritional status. This study evaluates the impact of multidisciplinary collaborative empowerment education (MCEE) in addressing these challenges. According to the inclusion criteria, 160 patients were recruited and randomly assigned to either the MCEE group (n = 80) or the control group (n = 80). The MCEE group received a tailored program consisting of psychological support, nutritional counseling, and educational interventions. Outcome measures, including psychological distress (using the Kessler Psychological Distress Scale), quality of life (using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire), and nutritional status (using hemoglobin, serum protein, and albumin levels), were evaluated at baseline and after four cycles of concurrent chemoradiotherapy. Post-intervention, the MCEE group showed significant improvements in psychological distress. QoL improvements were noted across all functional domains, including physical, emotional, cognitive, and social functions (all Ps ≤ 0.001), with significant reductions in fatigue, insomnia, and pain. Nutritional status also improved, with higher levels of hemoglobin, serum protein, and albumin, as well as less weight loss in the intervention group (all Ps ≤ 0.001). MCEE effectively reduces psychological distress, improves QoL, and enhances nutritional status in EC patients undergoing CCRT. This patient-centered, multidisciplinary approach offers a promising strategy for improving treatment outcomes and overall well-being in cancer care.

Introduction Peritoneal adhesions cause significant morbidity due to limited therapeutic options. Current strategies are limited by inconsistent efficacy and potential side effects. Plasma-activated solutions (PAS) exhibit anti-inflammatory and healing promoting properties with good safety, their efficacy in preventing peritoneal adhesions remains further investigation. Objectives This study aimed to investigate the therapeutic potential of PAS in preventing peritoneal adhesion formation and to elucidate its mechanisms. Methods Two murine peritoneal adhesion models (“ischemic button” and “cecum-peritoneum abrasion”) were established. Human peritoneal mesothelial cell was treated with LPS or TGF-β1 to model apoptosis and mesothelial-to-mesenchymal transition (MMT) in vitro. Apoptosis was quantified via flow cytometry and western blotting; ROS levels were assessed using immunofluorescence staining. MMT markers (western blotting) and inflammatory cytokines (ELISA) were analyzed. Histological evaluation included Masson’s trichrome and immunofluorescence staining. Results PAS-2 min significantly reduced adhesion scores compared to PBS controls (ischemic button: 6.250 ± 1.389 vs. 2.5 ± 2.268; abrasion: 7.333 ± 1.033 vs. 1.633 ± 1.333, p < 0.01). In vitro, PAS treatment decreased LPS-induced apoptosis in mesothelial cells by 8.14 % (flow cytometry: 39.10 % ± 1.47 % vs. 30.96 % ± 1.73 %, p < 0.01) and suppressed MMT markers, with N-cadherin and Vimentin expression reduced by 1.46-fold (p < 0.05) and 1.62-fold (p < 0.05). PAS also attenuated oxidative stress, decreasing general ROS levels by 3-fold (p < 0.001) and mitochondrial ROS (mtROS) by 2-fold (p < 0.01). Mechanistically, reactive nitrogen species (RNS) in PAS restored eNOS expression, attenuating apoptosis and MMT in mesothelial cells. Conclusion This study demonstrates that PAS prevents peritoneal adhesions via RNS-mediated eNOS restoration, suppressing oxidative stress, apoptosis, and MMT. These findings position PAS as a novel and promising therapy for adhesion prevention, warranting clinical translation.

Introduction Peritoneal metastatic carcinoma (PMC) faces limited therapeutic efficacy due to the peritoneal-plasma barrier and heterogeneous drug distribution. Current standard therapy (cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy, CRS + HIPEC) carries high complication rates. While pressurized intraperitoneal aerosol chemotherapy (PIPAC) improves distribution, its penetration depth remains suboptimal. Cold atmospheric plasma (CAP) induces tumor cell apoptosis via reactive oxygen and nitrogen species (RONS) but has not been applied in intraperitoneal therapy. Objective This study aimed to develop Pressurized Intraperitoneal Cold Atmospheric Plasma (PICAP), integrating CAP’s RONS-mediated antitumor effects with pressure-enhanced permeation technology. We sought to overcome limitations of conventional intraperitoneal therapies (uneven distribution, inadequate penetration) and evaluate PICAP’s therapeutic and prophylactic potential against peritoneal metastasis. Methods An in vitro peritoneal cavity model (carbon quantum dot tracers) and murine peritoneal metastasis models (MC38 colon cancer/ID8 ovarian cancer cells) compared permeability and efficacy among PICAP, PIPAC, and HIPEC. Mice received PICAP treatment (16 kV, 0.8 L/min He gas) for 0/5/10/15 min. Tumor burden, apoptosis, ROS levels, and mitochondrial function were analyzed via laparoscopy, histopathology, immunofluorescence, and flow cytometry. Prophylactic efficacy was also assessed. Results PICAP achieved full-thickness peritoneal penetration in vitro with significantly superior distribution uniformity versus PIPAC and HIPEC (p < 0.001). In murine models, 15-minute PICAP significantly reduced ascites volume and tumor burden, while markedly prolonging survival (p < 0.0001). Mechanistically, pressure-enhanced RONS delivery induced mitochondrial dysfunction (confirmed by JC-1 and MitoSOX assays), promoting tumor cell apoptosis and suppressing anoikis resistance. Prophylactic PICAP reduced surgically induced tumor implantation, achieving 100 % 90-day survival. Conclusion PICAP effectively overcomes peritoneal drug delivery barriers through pressure-enhanced RONS penetration and mitochondrial apoptosis pathways, significantly inhibiting peritoneal metastasis progression and demonstrating prophylactic potential. Its innovative design synergizing physical and biochemical effects offers a superior therapeutic strategy for PMC beyond existing modalities.

BackgroundGastrointestinal (GI) cancers impose a significant burden on global public health. Patients often experience mental health challenges due to physical changes and treatment-related symptoms, which can worsen their condition or delay recovery. Although research is mounting in this field, visual bibliometric analysis has not yet been conducted. This study aims to reveal the research hotspots and frontiers in this field using bibliometrics to guide future research.MethodsThe publications on GI cancer and mental health were retrieved in the Web of Science Core Collection from 2004 to 2024. VOS Viewer and CiteSpace, as commonly used bibliometric analysis tools, were employed to visualize the network structure of bibliometric data and uncover the evolving trends in scientific research fields. VOS Viewer was used to identify keyword co-occurrences, while CiteSpace was utilized to generate network visualizations, produce dual-map overlays of journals, and perform burst keyword analysis.ResultsA total of 1,118 publications were included for analysis. China had the highest number of publications in this field (341, 30.5%), while the United States held a central position (centrality = 0.48). The most productive author and institution were Floortje Mols and Tilburg University, respectively. Keyword analysis highlighted that “quality of life” (QoL) is a prominent research topic in the field, while “complications,” “cancer-related fatigue,” (CRF) “chronic stress,” and “epidemiology” have been identified as key areas for future research.ConclusionResearch interest in this field continues to grow. The research direction is mainly focused on personalized mental health interventions to improve QoL, as well as preoperative mental healthcare and ongoing care through internet-based multidisciplinary collaboration to reduce postoperative complications. More detailed clinical symptom assessment is needed to distinguish between CRF and mental health issues and to provide targeted intervention measures in the future. The mechanism of mental health effects on the occurrence and development of GI cancer will be a frontier.

Gastric cancer (GC) is a common malignant disease that has a fifth highest incidence and fourth highest mortality worldwide. The Warburg effect is a common phenomenon observed in tumors, which suggests that tumor cells would enhance glucose uptake by overexpressing multiple glucose transporters. Sodium glucose transporter 2 (SGLT2) is one of glucose transporters which highly expressed in several cancers, but its role in gastric cancer is still unclear. Our research found that there was a high expression level of SGLT2 in gastric cancer tissues. We found that Dapagliflozin (a SGLT2 inhibitor) could suppress gastric cancer cell proliferation and migration in vitro and tumor growth in vivo. In present study, we revealed how dapagliflozin would suppress gastric cancer progression in a novel mechanism. We proved that dapagliflozin decreased the expression level of OTU deubiquitinase 5 (OTUD5), which further increased the ubiquitination and degradation of YAP1. Overexpression of OTUD5 in gastric cancer cells partly reversed the anti-tumor effect of dapagliflozin. Our findings revealed a novel mechanism by which dapagliflozin has an antitumor effect on gastric cancer and proposed a beneficial strategy for the application of dapagliflozin in gastric cancer patients.

Background:Hepatitis B virus X protein (XTP1) is overexpressed in tumor tissues and regulates cancer progression. However, the molecular mechanism of XTP1 in gastric cancer (GC) is poorly understood. Hence, we aimed to dissect the underlying role of XTP1 in the development of GC.Methods:Lentiviruses were constructed and transfected into GC cells to upregulate or downregulate gene expression. The expressions of proteins in GC cells or tumor tissues were assessed by quantitative reverse transcription polymerase chain reaction (RT-qPCR), Western blotting, immunohistochemistry (IHC) assay, or the Gene Expression Profiling Interactive Analysis (GEPIA) database. Cell proliferation was assessed via methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay, Celigo cell counting assay, cell cycle analysis, and colony formation assay. Cell apoptosis was assessed by flow cytometry. The apoptosis-related proteins were evaluated using the human apoptosis antibody array. GC cell migration was detected by scratch wound-healing assays and Transwell migration assays. Potential downstream molecules were identified by the human GeneChip assay combined with bioinformatics analysis.Results:We found that XTP1 is overexpressed in GC tissues and is positively related to its pathological grade. XTP1 knockdown restrained the growth and migration of GC cells, while XTP1 overexpression promoted cell proliferation and suppressed apoptosis. A mechanistic study indicated that XTP1 knockdown inhibited cyclin-dependent kinase 6 (CDK6) expression and that CDK6 might be a potential downstream molecule of XTP1. Further study confirmed that CDK6 depletion also suppressed GC cell proliferation and migration and increased GC cell apoptosis. Moreover, rescue experiments verified that CDK6 knockdown abated the promotion of XTP1 overexpression on GC progression.Conclusions:XTP1 facilitated the development and progression of GC cells by activating CDK6. Therefore, the XTP1-CDK6 axis might be a potential therapeutic target for GC.

Objective:To develop the Peristome Skin Injury Risk Assessment Scale and to verify its reliability, validity and predictive performance in patients with colorectal cancer stoma.Methods:The initial assessment scale was developed through literature review and Delphi expert consultation. From February 2020 to April 2021, convenient sampling was used to select 290 cases of colorectal cancer stoma patients who were reexamined in the Oncology Surgery of the First Affiliated Hospital of Xi'an Jiaotong University as the research object. Item analysis, validity analysis, reliability analysis, receiver operating characteristic curve (ROC) were used to test the reliability, validity and predictive performance of the scale.Results:Exploratory factor analysis extracted a total of 4 common factors, namely general condition, stoma condition, postoperative condition, education and self-care condition, a total of 17 items, and the cumulative variance contribution rate was 85.144%. The scale-level content validity index was 0.941, and the item-level content validity index was 0.857 to 1.000. The Cronbach's α coefficient of the total scale was 0.824, the split-half reliability coefficient was 0.837, and the test-retest reliability coefficient was 0.819. There was a statistically significant difference in the scores of the Peristome Skin Injury Risk Assessment Scale in patients with colorectal cancer stoma between the injury group and the non-injury group ( P<0.05) . The area under the ROC curve was 0.838 (95% confidence interval: 0.785-0.891) . When the cut-off score was 39.5, the sensitivity of the scale was 0.849, the specificity was 0.759, the Youden index was 0.608, and the predictive performance was the best. Conclusions:The Peristome Skin Injury Risk Assessment Scale has good reliability and validity, and has high predictive performance, which is suitable for the assessment of the risk of peristome skin injury in patients with colorectal cancer in China.

Gastric cancer (GC) is the most frequent malignant tumor in the digestive system, with high metastasis potential and poor prognosis. This study aimed to investigate the prognostic value and biological function of thioredoxin domain-containing protein 9 (TXNDC9) in GC. The expression of TXNDC9 was analyzed based on The Cancer Genome Atlas (TCGA) database. The prognostic value of TXNDC9 was evaluated by Kaplan-Meier curves and Cox regression analysis. The mRNA and protein expression of TXNDC9 were analyzed using quantitative real-time PCR and western blot analysis. The effects of TXNDC9 on GC cell invasion and EMT were assessed in vitro, and its effects on tumorigenesis were confirmed using animal experiments. The activity of the NF-κB signaling pathway was examined by both in vitro and in vivo experiments. TXNDC9 was highly expressed in GC tissues and cell lines. A high level of TXNDC9 was associated with poor overall survival and served as an independent prognostic biomarker in GC patients. The knockdown of TXNDC9 led to restrained GC cell invasion, microtubule formation, and EMT in vitro, and suppressed tumorigenesis in vivo. In addition, the NF-κB signaling pathway was demonstrated to mediate the functional role of TXNDC9 in GC. In conclusion, this study found that high TXNDC9 predicted poor prognosis in GC, and served as an oncogene by enhancing tumor cell invasion and EMT through the NF-κB signaling pathway.

肠造口患者有着艰难的心理体验和较重的自我感受负担,医护人员应关注造口患者的内心真实感受,深入了解肠造口患者居家护理状况以及自我感知状态.采用质性研究方法,目的性抽样选择16名肠造口患者进行半结构式访谈,并运用Colaizzi分析法对资料进行分析、归纳主题.结果发现肠造口患者自我感知可归纳为4个主题:复杂的情绪反应;自我护理障碍;渴望支持,维护尊严;寻找自我价值.在住院期间为造口患者提供针对性指导、个性化健康教育外,还要做好患者出院后的延续性护理,并号召家庭及社会支持系统给予造口患者更多的关爱与支持,提高造口患者生活质量,助其回归正常社交和生活.

目的 汉化Sheffield护理评估与转诊简表,并评价其在我国恶性肿瘤患者中的信度和效度.方法 对Sheffield护理评估与转诊简表进行汉化及调试,在572例恶性肿瘤患者中进行问卷调查,并以中文版姑息关怀中的问题与需求问卷为校标,对汉化版量表进行信、效度分析.结果 (1)中文版Sheffield护理评估与转诊简表共6个维度,37个项目.(2)项目分析:各项目高分组和低分组得分比较,差异均具有统计学意义(t=3.576～8.293,均P＜0.05);各项目得分与总分的相关系数为0.579～0.741,量表各个项目间的相关系数为0.362～0.705(均P＜0.05).(3)效度:量表总内容效度指数为0.955;结构效度中,探索性因子分析共提取6个公因子,方差累计贡献率为79.273％,验证性因子分析显示模型结构拟合良好;校标效度中,量表总得分与中文版姑息关怀中的问题与需求问卷呈正相关(r=0.791,P＜0.01).(4)信度:总量表的Cronbach's α系数为0.862,折半信度为0.806,重测信度为0.856.结论 汉化后的Sheffield护理评估与转诊简表具有良好的信度、效度和临床实用价值,能够作为评价我国恶性肿瘤患者安宁疗护转介需求的调查工具.

Objective To explore the status of anticipatory grief in major caregivers of patients with advanced cancer and its influencing factors. Methods There were 329 major caregivers of patients with advanced cancer recruited between October 2017 and May 2018. The basic data questionnaire, Anticipatory Grief Scale and Perceived Social Support Scale were used in the investigation. Results The scores of anticipatory grief and perceived social support were 88.49 ± 16.47 and 60.33 ± 11.58 respectively. The result of multiple linear regression revealed that relationship with patients, perceived social support, gender and religion were associated with anticipatory grief and could explain 54.2％of the total variance. Conclusions Medical workers should provide assistance to the major caregivers of patients with advanced cancer, respect and encourage the appropriate participation of religious activities, encourage caregivers to fully express their feelings, decrease their adverse emotional reactions and improve their bereavement outcome.

目的 调查大肠癌化疗患者睡眠障碍现状,分析心理、社会因素对患者睡眠障碍的影响,为改善大肠癌化疗患者睡眠质量提供理论依据.方法 采用方便抽样的方法 选择2018年3月至2019年2月西安某三级甲等医院肿瘤内科大肠癌化疗患者269例,采用研究者自行设计的一般资料调查问卷收集患者一般人口学资料及疾病相关资料;采用匹兹堡睡眠质量指数(Pittburgh sleep quality index,PS QI)量表对患者的睡眠状况进行调查;采用心理痛苦温度计(distress the rmometer,DT)对患者进行心理痛苦状况测定,分析影响大肠癌化疗患者睡眠障碍的因素.结果 大肠癌化疗患者中,睡眠障碍率为56.88％,睡眠障碍者PSQI总分(10.23±2.96)分;影响大肠癌化疗患者睡眠障碍的单因素有性别、年龄、婚姻状况、家庭经济水平、生活满意度、家属关怀满意度、心理痛苦、担忧、抑郁;经Logistic回归分析得出性别、年龄、生活满意度、心理痛苦、担忧、抑郁是大肠癌化疗患者睡眠障碍发生的影响因素.结论 大肠癌化疗患者睡眠障碍发生率高,心理、社会因素是大肠癌化疗患者睡眠障碍发生的重要因素.

完全植入性静脉输液港(venous port access, VPA)是一种可植入皮下长期留置在体内的静脉输液装置.VPA可减轻病人反复静脉穿刺的痛苦,能防止刺激性药物对外周静脉的损伤,甚至可终身携带,且日常生活不受限制,是恶性肿瘤化疗病人常用的输液方式之一.完全植入式静脉输液港在给医务人员和病人带来了便利的同时,其并发症也是不容忽视的,尤其是导管相关性感染、导管相关性血栓和纤维蛋白鞘等并发症一旦发生,将给病人带来经济和心理的双重打击.

目的 探讨自我强化管理教育对于经外周静脉穿刺置人中心静脉导管(PICC)化疗的乳腺癌病人带管期间自我管理能力的影响.方法 乳腺癌病人130例,均行PICC化疗.采用随机数字表法将130例病人分为强化组和对照组,每组各65例,强化组给予自我强化管理教育措施干预,对照组仅给予一般护理及指导,观察两组干预前后的PICC自我管理能力(CPPSM)量表评分、PICC留置时间、带管期间并发症率.结果 干预前,强化组和对照组的日常生活管理、维护依从性管理、运动管理、信息获取、日常导管观察、异常情况处理、导管管理信心及CPPSM评分比较差异均无统计学意义(P＞0.05);干预后,强化组的日常生活管理、维护依从性管理、运动管理、信息获取、日常导管观察、异常情况处理、导管管理信心及CPPSM评分均高于对照组(P＜0.05);强化组的平均带管时间长于对照组(P＜0.05);强化组的并发症率为1.59％,对照组为11.48％,两组比较差异有统计学意义(P＜0.05).结论 自我强化管理教育可提升PICC化疗的乳腺癌病人带管期间自我管理相关评分,降低并发症发生率.

目的:调查胃癌术后患者心理痛苦程度,探讨影响胃癌术后患者心理痛苦的相关因素.方法:采取便利抽样的方法,选择2018年2月至2019年4月在西安交通大学第一附属医院肿瘤外科确诊的胃癌术后患者168例为研究对象,收集患者一般人口学资料,使用心理痛苦筛查管理工具(DMSM)进行胃癌术后患者心理痛苦程度及相关因素现况调查.结果:168例胃癌术后患者心理痛苦温度计(DT)得分为(4.27±2.38)分,DT≥4分者116例,心理痛苦阳性检出率为69.05％;引起胃癌术后患者心理痛苦相关因素中排列前3位的是担忧疾病、进食问题、经济问题;多因素回归分析显示,性别、年龄、文化程度、担忧疾病、进食、经济问题、疲乏、孤独、抑郁是影响胃癌术后患者心理痛苦的因素(P＜0.05).结论:胃癌术后患者心理痛苦发生率较高,在临床工作中医务人员应针对引起胃癌术后患者心理痛苦的具体因素给予个体化的处理.

目的 探讨影响胃癌术后及化疗中期患者心理痛苦的相关因素.方法 采取便利抽样的方法选择西安市某三甲医院肿瘤外科2018年2月至2019年2月胃癌术后患者135例为研究对象,使用研究者自行设计的一般资料调查问卷收集患者一般人口学资料及疾病相关资料、使用心理痛苦筛查管理工具进行胃癌术后1周及化疗第3周期结束后患者心理痛苦现状及相关因素调查.结果 135例胃癌术后患者中有133例患者完成本次研究,胃癌术后1周患者心理痛苦温度计(Distress Thermometer,DT)得分为(4.19±1.59分),DT≥4分者80例,心理痛苦阳性检出率为60.15％;引起胃癌术后1周患者心理痛苦相关因素有担忧、进食、财政/经济问题、疼痛;化疗第3周期结束后患者心理痛苦(DT)得分为(3.85±2.14)分,DT≥4分者71例,心理痛苦阳性检出率为53.38％,引起化疗中期患者心理痛苦相关因素有疲乏、恶心、财政/经济问题、记忆力下降/注意力不集中等,胃癌术后1周及化疗中期患者心理痛苦(DT)得分情况比较,差异无统计学意义(P>0.05).结论 胃癌术后1周及化疗中期患者心理痛苦发生率均较高,两个时期引起患者心理痛苦的因素各有不同.

目的 探讨肿瘤科护士的道德困境、工作投入、组织伦理氛围的现状及三者之间的相关性.方法 使用方便抽样,于2018年4-8月,选择陕西省西安市两所三甲医院的232名肿瘤相关科室的护士作为研究对象.使用组织伦理氛围量表、中文版护士道德困境量表和中文版工作投入量表进行问卷调查.结果肿瘤科护士的组织伦理氛围得分为(3.49±0.85)分.道德困境发生频率和困扰程度均分分别为(1.47±0.53)分和(1.56±0.60)分,总均分为(2.31±0.69)分.工作投入得分为(3.37±0.92)分.道德困境在肿瘤科护士组织伦理氛围和工作投入之间起部分中介作用,中介效应为0.327,且占总效应的52.8％.结论肿瘤科护理管理者应注意营造良好的组织伦理氛围,及时解决护士的道德困境,调动护士的工作积极性,从而提升临床护理服务质量.

该文通过综述国内外伤口造口失禁专科护理的发展,对伤口造口失禁专科护士相关概念进行介绍,分析总结了国外伤口造口失禁专科护士的服务模式、角色职责及培养情况,并对我国目前研究现状进行分析,同时对我国伤口造口失禁专科护士的发展提出了展望.