ObjectiveTo assess the reporting characteristics and quality of patient-reported outcomes (PROs) in randomized controlled trials (RCTs) of targeted therapy and/or immunotherapy for liver cancer.MethodsWe systematically searched six electronic databases for relevant RCTs published in English or Chinese from inception to April 17, 2025. The reporting quality of PROs was assessed using the CONSORT-PRO extension and the CONSORT 2010 guidelines.ResultsWe included 64 RCTs with 8,494 participants. Of these, 14 studies were confirmatory studies, 31 studies were exploratory studies and 19 studies were categorized as “Other” studies. 23.4% (15/64) of these RCTs reported PROs as the primary outcome. Twenty-seven patient-reported outcome measures (PROMs) about 17 relevant domains were observed in these studies. The domain with the highest reporting frequency was quality of life (53/64). Forty trials utilized a single PROM, while 24 trials employed multiple PROMs. The EORTC QLQ-C30 was the most often used PROM (25/53). Nineteen trials employed single-domain symptoms or specific functioning PROMs. Eight symptomatic adverse events were reported in less than 30% of studies. The mean score of the CONSORT-PRO adherence was 7.5 (3-14) for confirmatory studies, 5.8 (4-9) for exploratory studies and 6.0 (3-9) for other studies. The adherence to CONSORT 2010 was poor among the included trials. Only 3 trials achieved good reporting quality.ConclusionAmong the 64 included RCTs, the reporting of specific symptoms and the application of specific PROMs related to targeted and/or immunotherapy were poor. Meanwhile, the integration of PROs with clinical endpoints was suboptimal, and PRO data were seldom used to guide nursing practice. More importantly, the overall adherence to CONSORT-PRO among the included studies was low. Although confirmatory studies demonstrated higher scores than exploratory studies and other types of studies, there was considerable variation within this category. Future studies should prioritize the use of validated, standard disease-specific tools and strengthen the evaluation of treatment-related adverse events. Furthermore, we advocate establishing a collaborative framework that integrates medical, nursing, and patient perspectives. Future studies, particularly confirmatory studies and nursing intervention or supportive care studies, strictly adhere to the CONSORT-PRO guideline.

In busy clinical settings, timely access to comprehensive and actionable guideline recommendations can be constrained, motivating interest in large language models (LLMs) as adjunct tools for scalable evidence access and education. This study aimed to evaluate the performance of LLMs in domain-specific question-answering tasks within the nursing field and assess the effectiveness of GraphRAG technology in optimizing LLMs. A knowledge graph was constructed from high-quality clinical practice guidelines for pressure injury management and integrated with two base models—Qwen-turbo-0715 and DeepSeek-V3.1—to develop optimized versions (Qwen-turbo-0715-GraphRAG and DeepSeek-V3.1-GraphRAG). Model performance was compared between 10 non-specialist nurses, 10 specialist nurses, and the LLMs using a self-developed 25-item questionnaire designed with expert input to assess knowledge of pressure injury management. Group differences were analyzed using the Kruskal–Wallis H test with Bonferroni correction, followed by post hoc pairwise analysis. Average response times were also recorded for each model. Significant differences were observed among non-specialist nurses, specialist nurses, and LLMs (H = 17.662, P-value < 0.001). On this structured, guideline-derived benchmark under the study conditions, the LLM groups obtained higher scores than the nurse groups. The Qwen-turbo-0715-GraphRAG achieved the highest mean score (98.4), followed by DeepSeek-V3.1-GraphRAG (87.2), Qwen-turbo-0715 (86.4), ChatGPT-5 (82.4), and DeepSeek-V3.1 (77.6). GraphRAG optimization was associated with higher benchmark scores, but at the cost of longer response times. Overall, knowledge graph-enhanced LLMs showed more guideline-aligned and source-grounded outputs on this benchmark. However, these improvements were observed within a standardized, guideline-based assessment framework and may not capture the full complexity of clinical expertise. The findings support further evaluation of knowledge graph–enhanced LLMs in larger, more practice-oriented nursing settings and highlight the importance of considering the relative strengths of different base models before clinical application.

BACKGROUND:To systematically evaluate the effectiveness and safety of Chinese herbal medicine mouthwash (CHMM) in preventing ventilator-associated pneumonia (VAP) in patients with endotracheal intubation (ETT). METHODS:Computer searches were conducted for relevant randomized controlled trials (RCTs) in the China National Knowledge Infrastructure (CNKI), WANFANG DATA, Chinese Scientific and Technical Journal Database (VIP), Chinese Biomedical Literature Database (SinoMed), PubMed, Embase, Cochrane Library, and CINAHL Database from the establishment to April 5, 2023. The data were analyzed by RevMan 5.3 software. The methodological quality of papers was evaluated by the Cochrane version 5.1.0 and the certainty of evidence was evaluated by the GRADE system. RESULTS:We included 27 RCTs with 2426 patients. Most of the included studies were of poor methodological quality. Meta-analysis showed that CHMM (RR = 0.41, 95% CI: 0.34-0.50, P < .00001, low-certainty evidence) or CHMM + routine oral care (RR = 0.31, 95% CI: 0.18-0.56, P < .0001) could reduce the incidence of VAP compared to non-CHMM. CHMM may be superior to saline (low-certainty evidence) and chlorhexidine (moderate-certainty evidence) in preventing VAP (P < .05). CONCLUSION:Low-certainty evidence shows that CHMM may be more advantageous in reducing the incidence of VAP compared to non-CHMM. However, due to some limitations and the low certainty of evidence, we cannot recommend CHMM for routine clinical use at this time. Large-scale and high-quality RCTs are also needed to definitively evaluate the safety and clinical benefits of CHMM in the future.

Artificial intelligence (AI) has shown immense potential in the field of medicine, but its actual effectiveness and safety still need to be validated through clinical trials. Currently, the research themes, methodologies, and development trends of AI-related clinical trials remain unclear, and further exploration of these studies will be crucial for uncovering AI’s practical application potential and promoting its broader adoption in clinical settings. To analyze the current status, hotspots, and trends of published clinical research on AI applications. Publications related to AI clinical applications were retrieved from the Web of Science database. Relevant data were extracted using VOSviewer 1.6.17 to generate visual cooperation network maps for countries, organizations, authors, and keywords. Burst citation detection for keywords and citations was performed using CiteSpace 5.8.R3 to identify sudden surges in citation frequency within a short period, and the theme evolution was analyzed using SciMAT to track the development and trends of research topics over time. A total of 22,583 articles were obtained from the Web of Science database. Seven-hundred and thirty-five AI clinical application research were published by 1764 institutions from 53 countries. The majority of publications were contributed by the United States, China, and the UK. Active collaborations were noted among leading authors, particularly those from developed countries. The publications mainly focused on evaluating the application value of AI technology in the fields of disease diagnosis and classification, disease risk prediction and management, assisted surgery, and rehabilitation. Deep learning and chatbot technologies were identified as emerging research hotspots in recent studies on AI applications. A total of 735 articles on AI in clinical research were analyzed, with publication volume and citation counts steadily increasing each year. Institutions and researchers from the United States contributed the most to the research output in this field. Key areas of focus included AI applications in surgery, rehabilitation, disease diagnosis, risk prediction, and health management, with emerging trends in deep learning and chatbots. This study also provides detailed and intuitive information about important articles, journals, core authors, institutions, and topics in the field through visualization maps, which will help researchers quickly understand the current status, hotspots, and trends of artificial intelligence clinical application research. Future clinical trials of artificial intelligence should strengthen scientific design, ethical compliance, and interdisciplinary and international cooperation and pay more attention to its practical clinical value and reliable application in diverse scenarios.

BackgroundThe COVID-19 pandemic has required teachers and students to suddenly transition from face-to-face formats to distance education (DE). The uniqueness of nursing discipline is that it requires both theoretical and skills-based learning. Therefore, it is necessary to explore the influencing factors and effectiveness of DE in nursing education. This exploration can guide teaching practice and provide a basis for the future application of DE in nursing education.AimsTo describe the current distance education readiness and depth of learning among undergraduate nursing students and explore possible influencing factors. To determine the relationship between students’ distance education readiness and the depth of learning.DesignThis is a descriptive and cross-sectional online study.SettingsSchool of Nursing in a traditional Chinese medicine university, Beijing, China.ParticipantsA total of 222 undergraduate nursing students from a traditional Chinese medicine university were recruited.MethodsA questionnaire, which is composed of information form, the Online Learning Readiness Scale, and the Scale of Students Making Deep Learning, was used for data collection. Frequency, percentage, arithmetic mean, standard deviation, t-test, one-way ANOVA, and Pearson correlations were used in the analysis of the data.ResultUndergraduate nursing students have lower averages in distance education readiness and higher averages in the depth of learning. Significant differences in distance education readiness and depth of learning between different grade groups. A positive correlation was found between distance education readiness and depth of learning (r=0.894, p<0.001).ConclusionDistance education is a feasible approach to learning today. Undergraduate nursing students have exhibited poor readiness for distance education but demonstrated deeper learning conditions. Upper grades may lead to better learning outcomes. Better distance education readiness can lead to deeper learning. These conclusions prompt teachers and students to be prepared before participating in distance education to obtain better academic performance.

Purpose:To (1) investigate the changes in 5 domains (lack of family support, impact on finance, impact on daily schedule, impact on health, and self-esteem) of family caregiver (FC) burden and overall burden for first diagnosed colorectal cancer; (2) exploring changes in FC burden for colorectal cancer patients over time and analyze the trajectory and sub-trajectories of FC burden; and (3) identify the FC-related and patient-related factors most associated with the overall FC burden and each of its sub-trajectories.Patients and methods:This study is a descriptive longitudinal study. A convenience sampling method was used to recruit patients with colorectal cancer and their primary FCs from seven hospitals.Results:A total of 185 pairs of first diagnosed colorectal cancer patient and their FC were investigated for 4 times. The results reveal the overall burden and 5 domains of burden showed a trend of increasing first and then decreasing, and the burden was the heaviest at the time in the middle of chemotherapy. In the course of time, the aspect that caused the greatest amount of burden on average transitioned from the "effect on daily schedule" (range= 3.3 and 3.9) to the "effect on finances" (range= 3.1 to 3.4).Conclusion:Almost 88% of FCs have a either a moderate or a high level of burden. The quality of life of patients and the self-efficacy, social support and care ability of FCs have a great impact on the overall FC burden and each sub-trajectory.

通过对北京中医药大学护理实验中心的建设目标、建设思路、建设举措与成效等方面进行梳理，总结中心建设实践经验，以期为兄弟院校护理实验室建设提供参考。

目的 对乳腺癌首次手术患者需求的研究现状及需求内容进行总结.方法 计算机检索PubMed、Cochrane Library、Web of Science、Embase、中国知网、万方数据库、维普网、中国生物医学文献数据库中有关乳腺癌首次手术患者需求的文献,检索时限均为2013年1月1日-2022年12月31日.结果 共纳入17篇文献,研究设计以质性研究和观察性研究为主.乳腺癌首次手术患者的需求程度高,需求内容呈现多样性,主要包括信息需求、健康指导需求、情感需求和社会支持需求;不同年龄段、不同治疗阶段的乳腺癌手术患者的需求不同.结论 建议制订个性化需求干预计划,满足乳腺癌患者的多样化需求.

BackgroundThe inconsistencies between randomized clinical trials (RCTs) registrations and peer-reviewed publications may distort trial results and threaten the validity of evidence-based medicine. Previous studies have found many inconsistencies between RCTs registrations and peer-reviewed publications, and outcome reporting bias is prevalent. AimsThe aims of this review were to assess whether the primary outcomes and other data reported in publications and registered records in RCTs of nursing journals were consistent and whether discrepancies in the reporting of primary outcomes favored statistically significant results. Moreover, we reviewed the proportion of RCTs for prospective registration. MethodsWe systematically searched PubMed for RCTs published in the top 10 nursing journals between March 5, 2020, and March 5, 2022. Registration numbers were extracted from the publications, and registered records were identified from the registration platforms. The publications and registered records were compared to identify consistency. Inconsistencies were subdivided into discrepancies and omissions. ResultsA total of 70 RCTs published in seven journals were included. The inconsistencies involved sample size estimation (71.4%), random sequence generation (75.7%), allocation concealment (97.1%), blinding (82.9%), primary outcomes (60.0%) and secondary outcomes (84.3%). Among the inconsistencies in the primary outcomes, 21.4% were due to discrepancies and 38.6% resulted from omissions. Fifty-three percent (8/15) presented discrepancies in the primary outcomes that favored statistically significant results. Additionally, although only 40.0% of the studies were prospective registrations, the number of prospectively registered trials has trended upward over time. Linking Evidence to ActionWhile not including all RCTs in the nursing field, our sample reflected a general trend: inconsistencies between publications and trial registrations were prevalent in the included nursing journals. Our research helps to provide a way to improve the transparency of research reports. Ensuring that clinical practice has access to transparent and reliable research results are essential to achieve the best possible evidence-based medicine.

Aim: To investigate the current status of self-efficacy and physical activity among Chinese colorectal cancer (CRC) patients and explore the relationship between them.Design: A cross-sectional study.Methods: This study was conducted on 282 CRC patients in China. Structured questionnaires were used to collect data on demographic and clinical information, self-efficacy (Exercise Self-Efficacy Scale [ESES]) and physical activity (International Physical Activity Questionnaire-Short Form [IPAQ-SF]).Results: The median (interquartile range) total self-efficacy score for patients with CRC was 52.78 (42.08-61.11), and the median (interquartile range) total physical activity score was 1776.00 (1142.25-2812.05). Only 28.37% of CRC patients met the guideline recommendations for physical activity. The total self-efficacy score was significantly positively correlated with the total physical activity score (r = 0.123, p = 0.040).Patient or Public Contribution: CRC patients contributed to the data of this study. Hospital administrators facilitated the implementation of the study.

AimsTo review the content and efficacy of physical activity (PA) for cancer-related fatigue (CRF) among colorectal cancer survivors. DesignSystematic review. MethodsA comprehensive search for randomized controlled trials from inception to April 1, 2022, of the following database was performed: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and China Biology Medicine (CBM). RevMan5.4 software was used for performing meta-analysis. ResultsA total of eight qualified randomized controlled trials that included 542 survivors were included. PA interventions significantly reduced the CRF (SMD = -0.46; 95% CI: [-0.76, -0.15], Z = 2.67, p = 0.003); Subgroup analysis showed that fatigue was significantly improved when the length of interventions was at least 6 months and the weekly duration of PA was less than 150 min/week (SMD = -0.54; 95% CI: [-0.81, -0.27], Z = 3.87 and p = 0.0001; SMD = -0.67; 95% CI: [-1.15, -0.19], Z = 2.74 and p = 0.006); PA intervention with the length of <6 months and the volume of >= 150 min/week did not reduce fatigue (p > 0.05).

BACKGROUND:As pharmacotherapy often leads to adverse reactions, mind-body exercise (MBE) treatments have become a more popular option for treating depression in people living with breast cancer (BC). However, the most effective type of MBE treatment for this population remains unclear. AIMS:The aim of this systematic review and network meta-analysis (NMA) was to compare the efficacy of the different MBE modes for depression in people with BC. METHODS:A systematic search for randomized controlled trials (RCTs) from inception to March 25, 2023, was conducted in the following database: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang Data, China Biology Medicine, OpenGrey, and ClinicalTrials.gov. A traditional meta-analysis was conducted using the random-effects model to directly assess the effectiveness of various MBE interventions. Stata 16.0 software was used for performing the NMA. RESULTS:The NMA was performed in 32 eligible RCTs including 2361 participants. The efficacy of MBE treatments on depression was ranked as the following: Liuzijue (surface under the cumulative ranking curve [SUCRA] = 95.4%) > Tai chi (SUCRA = 76.9%) > yoga (SUCRA = 55.0%) > Baduanjin (SUCRA = 53.9%) > Pilates (SUCRA = 38.6%) > dance (SUCRA = 30.2%) > Qigong (SUCRA = 28.1%) > control (SUCRA = 21.9%). LINKING EVIDENCE TO ACTION:Our research showed that Liuzijue and Tai chi might be the most significantly effective MBE intervention for mitigating depression among BC survivors. Healthcare professionals could consider recommending Liuzijue and Tai Chi as a complementary therapy for BC survivors who experience depression.

Objective:To systematic review the efficacy and safety of external application of traditional Chinese medicine on treatment of breast cancer related lymphedema.Methods:CNKI, Wanfang Data, VIP, Sino-Med, The Cochrane Library, PubMed, Web of Science were searched for related randomized controlled trials, the retrieval time was from inception to May 25, 2020. Two researchers independently screened and evaluated the included studies. Meta-analysis was performed by RevMan 5.4 software.Results:A total of 16 studies involving 1 315 patients with breast cancer related lymphedema were included, and the methodological quality of the included studies was not high. Compared with conventional treatment, external application of traditional Chinese medicine combined with conventional treatment had advantages in improving the total efficiency( P<0.01) and quality of life( P<0.01), reducing pain( P<0.01) and improving upper limb function( P<0.01), without obvious adverse reactions( P>0.05), but there was no improvement in depression( P>0.05). Compared with conventional treatment, external application of traditional Chinese medicine could improve the total efficiency( P<0.01). Compared with placebo sticker combined with conventional treatment, external application of traditional Chinese medicine combined with conventional treatment can reduce circumference( P<0.05) and reduce pain( P<0.01), without obvious adverse reactions( P>0.05). Conclusions:Available evidence suggests that external application of traditional Chinese medicine may be a potential treatment method for breast cancer related lymphedema. Due to the poor methodological quality of the included studies, high-quality randomized controlled trials are still needed.

Objective:To systematically summarizes the application topics, evaluation dimensions, data sources and evaluation results of the RE-AIM framework in the nursing field implementation research and provides a reference for the outcome evaluation of the nursing field implementation research in the future.Methods:The scoping review framework of Levac was adopted to systematically search PubMed, Embase, Web of Science, Cochrane Library, CNKI, Wanfang Database and other databases, and the retrieval time was from establishment of databases to July 3, 2021. The literatures that were evaluated using the RE-AIM framework in the implementation science in the field of nursing were included, and the data were independently extracted and analyzed by 2 members of the research group.Results:A total of 9 literatures were included, with different research topics. The literature adopted three dimensions of effectiveness, adoption rate and implementation. Both quantitative and qualitative data were collected. The accessibility was 23.8%-100.0% and the adoption was 35.7%-100.0%. The sustainability dimension lacked long-term evaluation.Conclusions:When adopting the RE-AIM framework, nursing researchers should select important and appropriate dimensions and evaluation contents, collect quantitative and qualitative data, and report results truthfully, in detail and comprehensively.

ObjectivesTo assess the quality of clinical practice guidelines (CPGs) of ostomy care, and to analyze the status quo and challenges of guideline development.MethodsCPGs of ostomy care were systematically searched in relevant guideline websites and electronic databases, including PubMed, ProQuest, Web of Science, CNKI, VIP, WANFANG, and SinoMed, from January 1, 2012, to November 24, 2021. Two appraisers used the Appraisal of Guidelines for Research and Evaluation, 2nd edition (AGREE II) instrument to assess the quality of the included CPGs independently and objectively. The consistency of assessment was calculated using intraclass correlation coefficients (ICC).ResultsA total of 5 CPGs relevant to ostomy care were assessed by AGREE II and the general quality of them was good. There were two CPGs of grade A and three CPGs of grade B. The domain scope and purpose (87.78%) had the highest scores, followed by the clarity of presentation (87.22%), the rigor of development (69.17%), stakeholder involvement (68.33%), and editorial independence (65.00%), and the lowest was applicability (55.42%). The overall assessment score was 5.40. All the ICCs for the AGREE II appraisal conducted by the two appraisers were >0.75.ConclusionsThe five CPGs of ostomy care have the potential to be adopted in clinical practice. However, they still have some room for improvement, especially in the applicability domain. The development of ostomy care CPGs should follow the evidence-based progress and methodology of guideline formulation specifications while considering the effects of the CPGs and the practical issues.

Objective:To comprehensively collect the clinical research evidence of Wuqinxi, and provide reference for the future clinical research.Methods:China National Knowledge Infrastructure (CNKI), WanFang Database, VIP, China Biology Medicine disc (CBM), PubMed, Embase, Cochrane Library, and Web of Science were searched. The retrieval time limit was from the establishment of each database to March 31, 2021. After screening and extracting, SPSS 22.0 was used to analyze the basic characteristics, sample size, control and intervention measures, outcomes.Results:Totally 230 studies were included, of which 58.26% (134/230) were randomized controlled trial. The top 6 diseases were chronic obstructive pulmonary disease, osteoporosis, cervical pain, low back pain, diabetes and knee osteoarthritis. Common outcome included four items of blood lipid tests, blood glucose, immunological indicators and the evaluation of disease-related symptoms, such as pain, sleep and range of motion. The median frequency of Wuqinxi was once a day, 45 minutes each time, 5 days a week and lasted for 3 months. 94.78% (218/230) of the studies reported positive results. The safety and compliance of Wuqinxi intervention were good.Conclusions:The number of clinical studies on Wuqinxi is significantly less than Baduanjin and Taijiquan. It is necessary to formulate the report specification of intervention measures for Wuqinxi, so as to report the intervention plan of Wuqinxi more clearly and transparently.

Objective:To conduct a bibliometric analysis of the implementation research of the normalization process theory in the nursing field, so as to provide a reference for future in-depth research.Methods:We searched the China National Knowledge Infrastructure, WanFang, VIP, Biomedical Literature Database, PubMed, Web of Science, Embase, Proquest, Cochrane Central Register of Controlled Trials and CINAHL. The search period was from the establishment of the database to June 18, 2021, to collect all researches related to the normalization process theory in the nursing field. The year of publication, country or region and research institution of the article, fund project, research type and subject of the article were extracted and analyzed statistically.Results:A total of 154 articles were included, with the publication period from 2010 to 2021, of which 61.69% (95/154) were from the UK. The research scholars were mainly from colleges and universities, and 62.34% (96/154) of the research was qualitative research. The clinical disease spectrum included 18 diseases, which were distributed in 9 disease systems, and there were 3 diseases with an article frequency of more than 10 times, which were mental and behavioral disorders, endocrine, nutritional and metabolic diseases, and circulatory system diseases. The key research topics included 11 categories, mainly in chronic disease management, psychological care, mobile medicine, telemedicine and other aspects.Conclusions:The normalization process theory helps clinicians and nurses understand and assess the factors that facilitate or hinder the inclusion of health care interventions in routine practice. Based on the characteristics of this theory, nursing scholars in China can conduct qualitative research and hybrid research based on research problems, and try to localize the normalization process theory.

目的:通过中英文文献了解结直肠癌患者生命质量研究现状及发展趋势.方法:运用CiteSpace对中国知网(CNKI)、万方数据知识服务平台、中国生物医学文献数据库、Web of Science核心数据集、PubMed、Cochrane Library中收录的关于结直肠癌患者生命质量研究的中英文文献进行可视化分析.结果:检索得到中文文献1285篇,英文文献871篇,中英文文献发文量均呈上升趋势,相关研究关注的重点主要是结直肠癌患者造口、抑郁、免疫、肠道功能、化疗及化疗药物,但机构之间、学者之间合作程度及研究类型等方面存在一定差异.结论:中文文献相关研究起步晚、发展快,但在研究质量与研究深度等方面与英文文献相比还有一定差距;国内学者之间、机构之间应加强合作,关心患者肠道功能、心理状况,提高患者体力活动水平,开展更多高质量研究.

目的:分析大肠癌患者家庭照顾者在患者术后、化疗中期、化疗结束及化疗结束后3个月各时段照顾负担的水平变化情况.方法:本研究采用纵向研究设计,通过便利抽样在北京市、内蒙古自治区、河北省、河南省、江苏省的7家三级甲等医院,对185名大肠癌患者家庭照顾者在4个时间点采用一般自我效能量表、社会支持量表、照顾者照顾能力量表、简易应对方式量表及照顾者反应评估量表进行问卷调查.结果:大肠癌患者家庭照顾者普遍存在照顾负担,对照顾者影响较大的是"时间安排受打扰"和"经济问题"两个维度;照顾负担在随访期间先升后降,在化疗中期较为严重.增加照顾负担的因素为与患者同住、分担照顾患者人数少,照顾者一般自我效能、社会支持、照顾能力欠缺,较少采用积极应对和较多采用消极应对.结论:大肠癌患者家庭照顾者照顾负担随时间先上升后下降.临床医护人员应重点提高照顾者的自我效能、社会支持、照顾能力和促进其采取积极的应对方式.

目的 对涉及胃癌术后化疗自我管理的相关指南进行质量评价和内容分析,为制订我国胃癌术后化疗患者自我管理方案提供参考.方法 检索国内外临床实践指南网站、胃癌专业协会网站及部分中英文数据库,搜集胃癌术后化疗患者自我管理相关指南,检索期限为2015年7月至2020年6月.采用AGREE Ⅱ评价指南质量,并对各指南推荐意见进行汇总分析.结果 共纳入8部指南,总体质量评价为A级2部,B级3部,C级3部.胃癌术后化疗患者自我管理相关推荐意见涉及解决自身健康问题、如何进行决策、获取资源、建立医患合作关系、制订行动计划、自我监测6个方面35条.结论 纳入的指南部分质量较高,但指南开发的应用性、严谨性、参与人员等领域亟待加强.未来可借鉴国外质量较高指南进行本土化实践,并遵循国际标准尽快构建适应我国国情的胃癌术后化疗患者自我管理指南.