目的 探讨瓜蒌薤白半夏汤对心肌缺血再灌注损伤（MIRI）模型大鼠的心肌保护作用及机制。方法 本实验时间为2022年2月至2023年2月。采用随机数字表法将40只大鼠分为假手术组（A组）、模型组（B组）、瓜 蒌薤白半夏汤组（C组）、核因子κB（NF-κB）抑制剂组（D组），每组10只。C组、D组大鼠给予瓜蒌薤白半夏汤 预处理，A组、B组大鼠给予等量0.9%氯化钠溶液预处理，四组均连续干预7 d；A组大鼠于末次给药后1 h开胸，但不 结扎；B组、C组、D组大鼠于末次给药后1 h制备MIRI模型（采用左前降支结扎法制备），其中D组大鼠于再灌注前10 min腹腔注射吡咯烷二硫代甲酸铵。比较四组大鼠心肌梗死面积百分比、心肌组织形态学、血清炎症因子（IL-1β、 TNF-α）水平、血清氧化应激指标〔丙二醛（MDA）、超氧化物歧化酶（SOD）、乳酸脱氢酶（LDH）〕、心肌组 织超微结构及心肌组织Toll样受体4（TLR4）、NF-κB p65蛋白表达水平、mRNA相对表达量。结果 B组大鼠心肌梗 死面积百分比高于A组，C组和D组大鼠心肌梗死面积百分比低于B组，D组心肌梗死面积百分比高于C组（P＜0.05）。 HE染色结果显示，C组大鼠心肌组织纤维排列、心肌组织形态改变、横纹结构改变均优于B组；D组大鼠细胞核散落 在外侧明显。Masson染色结果显示，B组大鼠心肌细胞排列紊乱，少部分胶原纤维染色阳性；C组和D组大鼠心肌细胞 排列较规则，几乎无胶原纤维染色阳性。B组大鼠血清IL-1β、TNF-α、MDA水平及LDH活性高于A组，血清SOD活 性低于A组（P＜0.05）；C组和D组大鼠血清IL-1β、TNF-α、MDA水平及LDH活性低于B组，血清SOD活性高于B组 （P＜0.05）；D组大鼠血清IL-1β、TNF-α、MDA水平及LDH活性低于C组，血清SOD活性高于C组（P＜0.05）。透 射电镜扫描结果显示，B组大鼠细胞质中存在较多空泡，自噬体较多，C组大鼠细胞质中可见少数自噬泡，D组大鼠 细胞质部分呈空泡化。B组大鼠心肌组织TLR4、NF-κB p65蛋白表达水平、mRNA相对表达量高于A组，C组和D组大 鼠心肌组织TLR4、NF-κB p65蛋白表达水平、mRNA相对表达量低于B组，D组大鼠心肌组织TLR4、NF-κB p65蛋白 表达水平、mRNA相对表达量低于C组（P＜0.05）。结论 瓜蒌薤白半夏汤预处理可减轻炎症反应、氧化应激及抑制 心肌细胞自噬小体产生，进而缩小MIRI模型大鼠心肌梗死面积，保护心肌细胞，其机制可能与瓜蒌薤白半夏汤抑制 TLR4/NF-κB信号通路有关。

目的 观察和畅膏联合西药治疗阴虚阳亢型原发性高血压(EH)的疗效.方法 选取2021年2月—2022年1月在福建中医药大学附属人民医院心血管科门诊就诊的阴虚阳亢型原发性高血压患者78例,采用随机数字表法分为对照组和治疗组各39例,治疗期间对照组脱落2例,治疗组脱落1例.对照组予常规西药治疗,治疗组在对照组治疗基础上加服和畅膏,2组疗程均为12周.比较2组疗效、中医证候疗效及治疗前后动态血压、血管紧张素Ⅱ(AngⅡ)、血管细胞黏附分子-1(VCAM-1)、心踝血管指数(CAVI)、内皮型一氧化氮合酶(eNOS)、血流介导的血管舒张功能(FMD)变化.结果 2组疗效比较,治疗组总有效率为78.95％,优于对照组的56.76(P<0.05);2组中医证候疗效比较,治疗组总有效率为94.74％,优于对照组的56.76％(P<0.05);与治疗前比较,治疗后2组动态血压、AngⅡ、VCAM-1、CAVI均显著下降(P均<0.01),eNOS、FMD均显著升高(P均<0.01);治疗后2组比较,治疗组动态血压、AngⅡ、VCAM-1、CAVI均降低更显著(P均<0.05),eNOS、FMD均上升更显著(P均<0.05).结论 和畅膏联合西药能更好地改善阴虚阳亢型原发性高血压患者血管顺应性及内皮功能,较单用降压药具有更好疗效,可更好地稳定血压和改善临床症状.

Objective To investigate the protective effect and mechanism of pretreatment of Gualou Xiebai Banxia decoction on myocardial ischemia-reperfusion injury(MIRI)model rats.Methods This experiment was conducted from February 2022 to February 2023.A total of 40 rats were divided into sham group(A group),model group(B group),Gualou Xiebai Banxia decoction group(C group),and nuclear factor-κB(NF-κB)inhibitor group(D group)using random number table method,10 rats in each group.Rats in groups C and D were pretreated with Gualou Xiebai Banxia decoction,while rats in groups A and B were pretreated with an equal amount of 0.9%sodium chloride solution.All four groups were continuously intervened for 7 days.Rats in group A underwent thoracotomy at 1 hour after the last administration,but were not ligated;while rats in groups B,C,and D were used to prepare MIRI models using the left anterior descending branch ligation method at 1 hour after the last administration.Rats in group D were intraperitoneally injected with ammonium pyrrolidine dithioformate at 10 minutes before reperfusion.The percentage of myocardial infarction area,myocardial tissue morphology,serum inflammatory factor(IL-1β and TNF-α)levels,serum oxidative stress indicators[malondialdehyde(MDA),superoxide dismutase(SOD),lactate dehydrogenase(LDH)],myocardial tissue ultrastructure,Toll like receptor 4(TLR4),NF-κB p65 protein expression level and relative mRNA expression level in myocardial tissue were compared in the four groups of rats.Results The percentage of myocardial infarction area in group B was higher than that in group A,the percentage of myocardial infarction area in groups C and D was lower than that in group B,while the percentage of myocardial infarction area in group D was higher than that in group C(P<0.05).The HE staining results showed that the fiber arrangement,morphological changes,and transverse structural changes of myocardial tissue in group C were superior to those in group B,and the nuclei of group D were scattered and obvious on the outer side.The results of Masson staining showed that the arrangement of myocardial cells in group B was disordered,and a few collagen fibers were positively stained;the arrangement of cells in groups C and D was relatively regular,with almost no positive staining of collagen fibers.Serum levels of IL-1β,TNF-α,MDA and serum LDH activity in group B were higher than those in group A,while the serum SOD activity was lower than that in group A(P<0.05);serum levels of IL-1β,TNF-α,MDA and serum LDH activity in groups C and D were lower than those in group B,while the serum SOD activity was higher than that in group B(P<0.05);serum levels of IL-1β,TNF-α,MDA and serum LDH activity in group D were lower than those in group C,while the serum SOD activity was higher than that in group C(P<0.05).The scanning results of the projection electron microscope showed that there were many vacuoles and autophagosomes in the cytoplasm of group B,a few autophagosomes in the cytoplasm of group C,and partial cytoplasmic vacuolization of group D.The protein expression level and mRNA relative expression level of TLR4 and NF-κB p65 in myocardial tissue of group B were higher than those of group A,the protein expression level and mRNA relative expression level of TLR4 and NF-κB p65 in myocardial tissue of groups C and D were lower than those of group B,while the protein expression level and mRNA relative expression level of TLR4 and NF-κB p65 in myocardial tissue of group D were lower than those of group C(P<0.05).Conclusion Pretreatment of Gualou Xiebai Banxia decoction can reduce inflammatory response,oxidative stress,and inhibit the production of autophagosomes in myocardial cells,thereby reducing the myocardial infarction area and protecting myocardial cells in MIRI model rats.Its mechanism may be related to the inhibition of TLR4/NF-κB signal pathway by Gualou Xiebai Banxia decoction.

高血压病是一种常见于中老年人的慢性心血管疾病,随着社会飞速发展,人们的生活环境及饮食结构不断改变,高血压病逐渐年轻化发展.本文从"少阳为枢"的角度论述高血压病发病机制,针对高血压病的发病特点及临床表现以和解少阳法进行辨证治疗,并附以相关病例1例以供探讨.

心力衰竭是指各种原因导致心室舒张和(或)收缩功能障碍,心排血量不能满足全身组织基本代谢的临床综合征,以乏力、呼吸困难、体液潴留等为主要临床表现.中医学认为心力衰竭属"心衰"范畴,病位在心,以心气不足、心阳亏虚为主要病机.治疗心力衰竭时,以扶阳为要,以温振心阳为主要治法,使得阳气得补,阴翳自消,以期达到阴阳平衡的目的.

目的 探讨"阳微阴弦"病机在心肌缺血再灌注损伤治疗中的应用效果,为减轻心肌再灌注损伤和提高患者生活质量提供新的思路.方法 整理分析胸痹"阳微阴弦"相关条文及经典方剂,查阅中外文献,明确心肌缺血再灌注损伤的概念,结合现代医学和药理学研究,从"本虚""标实"两个方面阐述心肌缺血再灌注损伤的病因病机.结果 心肌缺血再灌注损伤属于中医学"胸痹"范畴,"阳微阴弦"正中其病机,可指导冠心病术前"未病先防"、术后"瘥后防复",有效弥补再灌注治疗的不足.结论 胸痹"阳微阴弦"的病机理论为确立"扶正祛邪"法提供了理论基础,现将其扩大到心肌缺血再灌注损伤同样适用,临床应发挥传统医学治疗优势,分阶段辨证论治,寻因求本,以期"阴平阳秘".

中医理论认为新型冠状病毒肺炎(NCP)属瘟疫范畴,由"疫毒"致病,来势凶猛,变化多端,病情进展易出现耗气、动血、扰神等症状,符合"逆传心包"的传变规律.基于叶天士"逆传心包"理论,分析心肺间密切的相关性,认为NCP的心血管损害以气虚血瘀为主要病机,正虚邪实并见,遵循中医学"既病防变"指导原则,气血同调,形神兼顾,对防治新型冠状病毒所致心血管损害有重要价值.

本文从理论内涵、相关实验研究以及气候对心血管疾病的影响等方面探讨"心应夏"理论在心血管疾病中的意义,发现冬季低温及夏季高温天气与心血管疾病的发生密切相关,提出心阳在心血管疾病中的重要性.基于该理论,夏季应顺应养长之性温养心阳,心阳虚患者在冬季尤应注重充补心阳,高温天气时不忘顾护阴液,平调阴阳,达到阴平阳秘的状态,以此降低心血管疾病的发生率.

目的 探讨和畅膏治疗阴虚阳亢型原发性高血压临床疗效及对踝臂指数(ABI)、臂踝脉搏波传导速度(baPWV)、颈股脉搏波传导速度(cfPWV)、颈动脉内膜中层厚度(IMT)、阻力指数(RI)、血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及高密度脂蛋白胆固醇(HDL-C)的影响. 方法 将92例阴虚阳亢型原发性高血压患者按数字表法随机分为对照组和试验组各46例.对照组予以常规西药治疗,试验组在对照组治疗基础上加用和畅膏口服.2组疗程均为12周,疗程结束后评价降压效果及中医证候疗效,同时检测2组治疗前后ABI、baPWV、cfPWV、IMT、RI、TC、TG、LDL-C、HDL-C变化情况. 结果 与治疗前比较,治疗后2组cfP-WV、baPWV、IMT、RI、TC、TG、LDL-C均显著下降(P＜0.05);与对照组比较,试验组的降压效果、中医证候疗效更优(P＜0.05),baPWV、cfPWV、RI、TC、TG、LDL-C水平降低更显著(P＜0.05). 结论 和畅膏可以增强阴虚阳亢型原发性高血压患者的中医证候疗效,具有协同降压效果,并能有效降低baPWV、cfPWV、R1、TC、TG、LDL-C水平,抗动脉粥样硬化,改善临床症状.

目的:探讨增强型体外反搏(EECP)对冠心病患者支架置入术后 3 年临床预后的影响. 方法:选择行经皮冠状动脉支架置入治疗的冠心病患者200 例,随机分为 EECP 组(100 例)和对照组(100 例), EECP 组在常规西药治疗的同时行积极的 EECP 治疗,36 次 / 疗程,每年2个疗程.对照组行常规西药治疗和消极的EECP治疗.随访 3 年,比较两组患者颈动脉内膜中层厚度、心脏功能、支架内再狭窄的发生率、主要不良心血管事件(MACE)发生率及全因死亡率.

Objective:To explore effects of Yijing pill on cardiac haemodynamics and myocardial apoptosis in diabetic (DM)rat.Method:The model of DM rat was indeced by U-sing streptozotocin and then the DM rats were divided into the Yijing pill treatment group (Daily intragastric administration of 3ml decoction,equivalent to 10. 71g/kg crude drug,n=20),Benner Pury treatment group (Daily intraperitoneal injection of 10ug/kg,n=20)and the model group (Daily intragastric administration of 3ml normal saline,n=20).In addition,another 20 rats were selected as control group,and 3ml normal saline was poured into the stomach every day.The Left Ventricular Pres-sure (LVP),maximum left ventricular pressure rising and dropping rates (±dp/dt)and Left Ventricular End Dias-tolic Pressure (LVEDP)was measured by arterial catheterization after feeding for 12 weeks.After weighing the weight of rats,the heart and left ventricle of each group rats was taken out and weighed,and then the Heart MassIndex (HMI)and Left Ventricular Mass Index (LVMI)were calculated.Part of the left ventricle was used to make the myocardial tissue sections and TUNEL method was used to detect the apoptosis of myocardial cells.Results:A-nalysis of variance showed that there were significant differences in cardiac hemodynamic parameters,HMI and LV-MI in all groups (P <0.01).Compared with the normal group,the LVP,+dp/dtmac and -dp/dtmax significantly decreased in all DM groups,and Model group < Yi Jing Tang treatment group < Benner Pury treatment group (all P <0.01 ).Compared with the normal group,the LVEDP significantly increased in all DM groups,and Model group > YiJing tang treatment group > benner pury treatment group (all P <0.01 ).Compared with the normal group,the HMI and LVMI was significantly increased in all DM groups (P <0.01 ),but there was no significant difference between the YiJing tang treatment group and the model group (P >0.05 ).The apoptosis of myocardial cells in DM rats appeared in twelfth weeks,which in treatment group was lighter than the model group (P <0.05). Conclusion:The myocardial apoptosis has emerged in DM rats in the first 12 weeks,and Yijing pill can inhibit myo-cardial apoptosis in DM rats.

Objective To investigate the effect of Tianma Gouteng Decoction of carotid femoral arterial pulse wave velocity(c-fpwv),and flow mediated vascular as the main outcome measures were used to assess endothelial(FMD)and symptom classification,in order to explore the Tianma Gouteng Decoction to improve vascular compliance and endothelial function effect.Methods According to the diagnostic criteria, inclusion criteria and exclusion of selection criteria for primary hypertension 1 level(liver yang hyperactivity type)of 60 cases of patients were randomly divided into two groups,TCM(traditional Chinese and Western medicine=hydrogen chlorine thiazide+Tianma Gouteng Decoction)treatment group(30 cases), conventional(western medicine=hydrochlorothiazide) treatment group (30 cases),a course of 12 weeks,and compared with normal healthy people (30 cases).ResultsCompared with the normal group,the C-FPWV of patients with hypertension was accelerated. The C-FPWV of Chinese medicine treatment group was significantly decreased(P< 0.01), and the C-FPWV in the conventional treatment group was not significantly different (P> 0.05),and the C-FPWV in the Chinese medicine treatment group was significantly better than that in the conventional treatment group(P< 0.01). Compared with normal group, FDM was significantly lower in hypertensive patients than that in normal group(P< 0.01),and FMD in the conventional treatment group was not significantly different(P> 0.05),the two groups were significantly higher than those in the conventional treatment group(P< 0.01). Before and after treatment,blood pressure and symptom classification were changed. The blood pressure and symptom classification before and after treatment were significantly decreased(P< 0.01),the two groups compared with the control group was significantly different(P< 0.01).Conclusion Tianma Gouteng Decoction and antihypertensive drug can be effective in improving vascular adaptation and endothelial function than single use of antihypertensive drugs and can better stabilize blood pressure,and improving symptoms.

ObjectiveTo observe the effect of enhanced external counterpulsation (EECP) combined with TCM syndrome (phlegm and blood stasis obstructing) in treatment of unstable angina pectoris (UA).Methods Randomly divided into control group, medication group and ECP treatment group. The control group was treated with routine western medicine plus EECP, drug treatment group was treated with routine western medicine and traditional Chinese medicine phlegm and promoting blood circulation, regulating qi Kuanxiong therapy, counterpulsation in the treatment group based on conventional western medicine and traditional Chinese medicine treatment plus EECP. 12 days for a course of treatment, enhanced external counterpulsation 1 hour/ times, continuous treatment of 3 courses. Observed the angina pectoris of improving symptoms and ECG changes and the occurrence of adverse reactions before and after treatment.Results All treatment groups of angina pectoris symptoms and ECG changes were improved, the control group, drug treatment group curative effect close, counter pulsation therapy group was better than control group, drug group.Conclusion The therapeutic effect of enhanced external counter pulsation combined with traditional Chinese medicine treatment is good, and no adverse events occured.

目的:观察单硝酸异山梨酯缓释胶囊治疗心绞痛的疗效、安全性及临床依从性.方法:入选2012年1月～ 2013年4月在我院就诊的心绞痛患者400例,随机分为观察组(n =200,观察组患者在心绞痛常规治疗的基础上增加单硝酸异山梨酯缓释胶囊治疗)和对照组(n =200,给予心绞痛常规治疗),比较两组患者临床效果及不良反应.结果:两组患者治疗3个月后,观察组患者显效率、无效率及总有效率分别为71.0％、3.0％、97.0％与对照组患者54.5％、14.0％、86.0％相比,差异均具有显著统计学意义,均P＜0.05;用药依从性较好者临床效果显著优于用药依从性较差者,差异有统计学意义,P＜0.05;对照组患者不良反应发生率为15.5％与观察组患者23.5％相比,差异无统计学意义,P＞0.05.结论:单硝酸异山梨酯缓释胶囊治疗心绞痛的疗效显著、相对安全,并且与患者用药依从性有关.

目的:观察联合“心痛贴膏”穴位贴敷治疗冠心病不稳定性心绞痛与单纯西药治疗之间的疗效差别.方法:将冠心病不稳定性心绞痛患者随机分成联合“心痛贴膏”穴位贴敷治疗组和单纯西药治疗组,治疗一周,观察心绞痛发作疼痛程度、持续时间、频率及硝酸甘油用量、心电图ST段下降导联数(NST)和ST段压低总和(ΣST)以及生活质量改善状况.结果:联合“心痛贴膏”穴位贴敷治疗组较单纯西药治疗组心绞痛发作程度减轻,持续时间、频率减少(P＜0.05)、硝酸甘油用量明显减少(P＜0.05),心电图显著改善(P＜0.05).结论:联合“心痛贴膏”穴位贴敷治疗冠心病不稳定性心绞痛,具有增强疗效、改善生活质量的作用.

Objective To observe the effect of song ling xue mai kang on blood vessel compliance and endothelial function.Methods the 90 patients with essential hypertension were randomly divided into control group(n=45) treated with hydrochlorothiazide and irbesartan and treatment group(n=45) treated with hydrochlorothiazide,irbesartan and song ling xue mai kang for 12 weeks.Results C-FPWV was decreased in treatment group(P0.01) and control group(P0.05).And compared with control group,C-FPWV was lower in treatment group(P0.01).FDM was reduced in treatment group and control group(P0.01 respectively).And FDM was lower in treatment group than that in control group(P0.01).Blood pressure and grade of symptom were declined in control group(P0.01) and treatment group(P0.01).And compared with control group,blood pressure and grade of symptom were lower in treatment group(P0.01).Conclusion Combined with Song ling xue mai kang and antihypertensive drug,it is effective to ameliorate the compliance and endothelial function of artery in hypertensive patients,which is better to control blood pressure and improve symptom than antihypertensive drug only.

Objective To observe the clinical efficacy of Astragalus Salvia drink on the NT-proBNP,CRP levels and heart function in patients with chronic heart failure and qi asthenia causing blood stasis and its effects on NT-proBNP levels and CRP levels. Methods 50 outpatients and hospitalized patients were randomly divided into control group and treatment group.The heart function of patients was classified according to the U.S. in New York Heart Association functional class classification methods. And uniform standards were developed to determine clinical efficacy. Control group was treated with conventional western medicine and treatment group was treated with conventional western medicine and Astragalus Salvia drink. The treatment was lasted 12 weeks. After 12 weeks of treatment blood samples were collected.NT-proBNP levels were detected with the rapid chemiluminescence immunoassay assay and CRP levels were detected with nephelometry. The heart function of patients was observed and recorded after 12 weeks treatment. Results After treatment,plasma NT-proBNP levels and CRP levels were significantly decreased in both groups(P 0.01). Compared with the control group,plasma NT-proBNP and CRP levels were significantly decreased in treament group after treatment(P 0.05). Cardiac ultrasound showed that there were improvements in varying degrees after treatment in both groups.There was statistically significance in both groups compare after treatment(P 0.05). Conclusion Conventional western medicine with Astragalus Salvia drink were better to improve the heart function,reduced plasma NT-proBNP level and CRP level.Therefore it played a role in the treatment of chronic heart failure.

目的观察松龄血脉康胶囊对慢性心力衰竭(CHF)患者的临床疗效及其对超敏C反应蛋白(hs-CRP)、B型利钠肽(BNP)水平的影响。方法62例患者按照住院顺序随机分为对照组和治疗组,根据美国纽约心脏病学会(NYHA)心功能分级方法分级,并制定统一疗效判定标准。对照组予常规西医治疗;治疗组在西医常规治疗基础上加服松龄血脉康胶囊。两组疗程均为12个月。治疗1个月后对采集血标本,用酶联免疫吸附法(ELISA)检测hs-CRP、BNP水平;治疗12个月后对患者的心功能进行观测并记录。结果两组治疗后血hs-CRP和BNP水平均明显下降(P<0.05),与对照组治疗后比较BNP有统计学意义(P<0.05),而血清hs-CRP水平无统计学意义(P>0.05);心脏超声检测示治疗后两组均有不同程度改善,但两组治疗后比较无统计学意义(P>0.05),但治疗组显示了进一步改善的趋势。结论松龄血脉康胶囊对于心血管疾病的炎症病理过程有着下调、阻抑的作用,从而对防止血管、心肌重构起到一定作用。

【目的】通过测定血栓素A2(TXA2)与前列环素(PGI2)代谢产物TXB2、6-Keto-PGF1α水平及其比值(TXB2/6-Keto-PGF1α,T/K),观察冠心宁注射液对不稳定型心绞痛(UAP)患者TXA2与PGI2比值的影响。【方法】120例冠心病不稳定型心绞痛患者随机分为冠心宁组和常规治疗组。治疗前和治疗后2周分别测定TXB2,6-Keto-PGF1α水平,计算TXB2/6-Keto-PGF1α(T/K)比值。【结果】常规治疗组治疗后6-Keto-PGF1α明显升高(P<0.05),冠心宁组治疗后6-Keto-PGF1α明显升高(P<0.01),两组治疗后TXB2、T/K比值明显下降(P<0.01),冠心宁组治疗后6-Keto-PGF1α升高水平,TXB2、T/K比值下降水平与常规治疗组相比,有显著性差异(P<0.01)。UAP患者血浆TXB2、T/K明显高于健康老年人,而6-Keto-PGF1α明显低于健康老年人(P<0.01)。【结论】①UAP患者血浆TXB2、T/K明显高于健康老年人,而6-Keto-PGF1α明显低于健康老年人。②冠心宁注射液可减少TXA2的生成,促进PGI2分泌,纠正TXA2/PGI2比值失衡;冠心宁治疗不稳定型心绞痛的机制可能与调节TXA2/PGI2的平衡有关。冠心宁在UAP治疗中是一种安全有效的药物。

目的观察松龄血脉康对高血压患者血液流变学的影响。方法选择我院经血液流变学化验确诊异常的高血压患者166例,随机分为治疗组90例和对照组76例,进行给药前、后自身比较和两组间比较。结果治疗组患者治疗前、后全血高切、低切、血浆黏度、全血还原黏度、纤维蛋白原、胆固醇、三酰甘油间差异均有显著性意义(P<0·05);对照组患者治疗前、后胆固醇、三酰甘油间差异有显著性意义(P<0·05);两组患者治疗后全血高切黏度、血浆黏度、全血还原黏度间差异均有非常显著性意义(P<0·05)。两组患者临床疗效间差异有显著性意义(P<0·05)。结论松龄血脉康对血液流变学多项指标有影响,且能改善患者的临床症状,提高生活质量,可作为防治心脑血管疾病的药物。