目的 以功能性腹泻(Functional Diarrhea,FD)作为疾病载体,从肠道褪黑素(Melatonin,MT)及5-羟色胺(5-hydroxy tryptamine,5-HT)信号系统入手,研究电针大肠俞募穴调控FD大鼠肠道动力的作用机制.方法 30只SPF级SD大鼠随机分为空白组、模型组、电针组,每组10只.空白组采用生理盐水灌胃,其余2组采用0.3g/mL的番泻叶煎剂灌胃建立FD模型.灌胃开始当天即每天进行相关干预.电针组进行捆绑束缚,电针刺激天枢、大肠俞,留针20min.空白组和模型组使用相同方法 束缚20min,但不做其他处理.以上干预1次/日,连续干预10天后,观察各组大鼠排便情况,经ELISA检测肠道组织MT、5-HT含量.结果 造模后,模型组24h稀便粒数、稀便率、稀便级、腹泻指数、结肠和回肠MT、5-HT水平均高于空白组(P<0.05).电针组24h稀便级、腹泻指数、结肠和回肠MT、5-HT含量较模型组明显降低(P<0.05).结论 造模可导致大鼠结、回肠5-HT、MT水平上升,电针大肠俞募穴可降低结、回肠5-HT、MT水平.说明腹泻的发病与MT、5-HT水平升高有密切的关系,针刺可以改善腹泻大鼠的异常排便情况,可能通过对肠道MT、5-HT水平的调控,影响5-HT信号系统功能,从而对FD大鼠肠道动力进行调节,令异常的肠道动力恢复正常.
本文以典型妇科癥瘕病案为例,介绍导师吴克明教授运用中成药消癥散结的临床经验,旨在为临床医生和患者提供有效的药物治疗方法,以尽量减少患者手术创伤与痛苦.吴教授运用中医药治疗妇科疾病强调西医辨病与中医辨证相结合,对于妇科癥瘕包块属良性而无手术指征者,因为一般病程和疗程较长,治疗主张不宜过用"汤剂荡逐",而宜用"丸药缓图",且癥瘕久病入络,故常选择包含有昆虫和动物类的中成药,以软坚散结、辛窜入络、化瘀消癥,既方便患者坚持服用,又节省中药材资源.
出于多种原因导致大学生对其所学专业的不自信,不利于大学生的身心健康发展,最终会使其产生得过且过、厌学甚至辍学的心态.积极心理学是一门从积极角度出发研究传统心理学研究对象的新兴学科,文章对大学生专业不自信因素进行分析,并基于积极心理学视角对培养大学生专业自信心的可靠路径进行讨论,以期为提高大学生身心健康、专业素养乃至推动专业发展奠定一定的基础.
“文化自信”是党的十九大报告中强调的中国特色社会主义重要的发展力量之一.高等中医药院校的“非医学”类专业往往并非学校的重点发展对象,此类专业的大学生通常会对所学专业的发展缺乏自信.对此,应创新“文化自信”的相应内涵,重建学生的专业自信,加强理想信念教育,努力提升学科专业实力,以培养出有坚定信念、积极自信、专业能力突出的合格人才.
专业自信是影响大学生学习积极性、学习效率、学习质量等的重要影响因素.文章以成都中医药大学为例,通过调查问卷的形式对部分专业的学生进行调研,从个人自信和专业自信两方面了解学生的自信程度,并讨论培养大学生专业自信的途径,从而为提高大学生专业自信、稳固专业人才培养质量提供有效建议.
卵巢早衰(premature ovarian failure,POF)是指育龄期女性40岁之前出现闭经、月经紊乱、促性腺激素升高和雌激素水平降低,伴或不伴有围绝经期症状的内分泌疾病.吴教授认为,卵巢早衰以肾虚为主要病机,与肝脾密切相关,其主要治法为补益肾精,养血活血,佐以疏肝健脾理气、调养冲任,使残留卵泡复苏和发育,以恢复卵巢功能,助孕保胎.
糖尿病视网膜病变(DR)是糖尿病的重要微血管并发症之一,是工作年龄成人的主要致盲疾病,随着人们生活水平的提高,DR患病率逐年上升,西医的激光治疗及玻璃体切割等治疗方法均有各自的局限性,因此寻求更为经济有效的治疗方法,是广大患者的迫切需求,本文就近年年中医治疗DR进展进行综述.
早发性卵巢功能不全和卵巢早衰是女性由于各种原因引发卵巢内卵泡耗竭及卵巢功能衰退而发生的月经不调或闭经现象,后期伴有潮热汗出、面部颧红、性欲低下等围绝经期症状.吴克明为成都中医药大学妇科教授,博士生导师,四川省名中医,从事中医和中西医结合妇科临床、科研和教学工作30多年,笔者读研期间跟师临诊,发现导师在诊治卵巢储备功能下降(DOR)、早发性卵巢功能不全(POI)、卵巢早衰(POF)病症方面经验丰富,认为POI和POF多系肝肾亏虚,精血不足,冲任失养,以至胞宫无血可下所致,遵循中医“治未病”思想分期诊治,指导患者监测排卵期适时同房试孕的方法临床疗效较佳,现将导师临床经验简介如下.
随着计算机技术、网络技术迅猛发展,基层中医院的信息化建设已成为全国医疗系统信息化进程中的重要组成部分.本项目的研究内容是在社区等基层中医治疗机构建立医院信息管理系统,加强和规范中医医院信息化建设.通过对成都中医药大学附属医院及武侯区、高新区社区医院的日程管理与运行进行调研,与医护人员及患者的交流,确定了系统应达到的基本功能.建立目标系统之后,不仅能够快速实现中医药信息资源共享、互联互通,还能够帮助建立专业的中医药信息化复合型人才队伍,从而保障了中医药信息化工作的顺利开展.
目的:观察不同提取方式的抗缺氧含片对提高小鼠缺氧耐受力功能的影响.方法:根据《保健食品检验与评价技术规范》(2003年版)中的3个动物实验评价抗缺氧含片的耐缺氧功效.结果:抗缺氧含片具有提高小鼠常压耐缺氧存活时间,及提高小鼠急性脑缺血性缺氧喘气时间的作用.结论:抗缺氧含片具有提高缺氧耐受力的功能.
Objective:By using Traditional Chinese Medicine Inheritance support software (V 2.5) to analyze the composing and medicating regularities for Zhenbu disease of Tibetan medicine in the Encyclopedia of Chinese Medicine ·Tibetan Medicine,Tibetan medicine composition preparation of modern research and clinical application and Common interpretation of Tibetan Medicine.Methods:Traditional Chinese Medicine Inheritance support software was used to build a prescription database of Tibetan medicine treating Zhenbu disease.The software integration date mining method was used to achieve frequency statistics,prescription regularity and new prescription analysis.Results:Based on the analysis of 118 cases of Zhenbu disease prescriptions,the frequency of each herb included in the database was computed,8 new prescriptions were mined from the database.This study indicated that Tibetan medicine treating Zhenbu disease were mostly those for activating blood and regulating Qi,activating water movement and eliminating dampness and some for relaxing sinew and collaterals.Conclusion:The complex composing and medication regularities of Tibetan medicine treatment of Zhenbu disease have been clarified by TCM inheritance system.That would provide the reference for the clinical treatment of Tibetan really brucellosis and the new development.
藏羌彝走廊同时存在多种民族文化,其中,藏族、羌族、彝族医药古老而独具特色.文章以医学人类学视野,从环境、社会、心理及文化等方面,探索该走廊中藏、羌、彝医药对健康和疾病独特的认知,并对其文化特色进行研究,有利于在保护藏羌彝走廊地区生态和文化多样性、促进地区经济发展的前提下,保障藏羌彝走廊民族医药可持续协调发展.
吴克明教授,四川省名中医,成都中医药大学博士硕士生导师,为四川省有突出贡献的优秀专家,从事中医和中西医结合妇科临床工作30余载,于中医及中西医结合妇科基础理论、临床皆有精深的造诣,对中医及中西医结合妇科的发展做出了卓越的贡献.善于运用古代名方化裁及中成药灵活使用治疗妇科常见疾病.他将中医基础理论与临床实践有机地结合起来形成自己鲜活的诊疗经验而颇获良效.临证主张“先辨病,次辨证,再议法,后议药”.笔者有幸随师临证学习,受益颇多,现将其学术思想及治疗妇科常见病的经验总结介绍如下.
At present, the postgraduate education of Tibetan is still in its initial stage. Because of the relative lack of talent in Tibetan Medicine and the cultivation and development of Tibetan medical postgraduates need to experience a long period, which slow down the inheritance and development of Tibetan medicine. On the basis of previous work, which had done by the National Medical College of Chengdu University of Traditional Chinese Medicine, the National Medical College combine with the social needs about high level talents in Tibetan and put forward an idea about a teaching reform. The exploration of teaching reform carried out with exploring a new approaches for the development of postgraduate education in Tibetan medicine as the goal, with the integration of apprentice education and college education as the starting point, and from the aspects of improving the teaching quality, perfecting the teaching system, developing a variety of educational channels and educational resources. The exploration provided the conditions for the teaching reform of teaching innovation and reference for the new education model of Tibetan medicine.
The demands for the elderly care service in China is increasing with the development of aging popu-lation. But the development of geriatric nursing education was severely lagged behind and the lack of geriatric nursing tal-ents had become an outstanding problem. This paper analyzed the present situation and development trend of geriatric nursing education in the following respects, including major setup, textbook compilation, curriculum setting, teaching conditions and professional qualifications, in order to provide references and basis for its development.
随着“生物-心理-社会”新的医学模式的发展以及优质护理服务的开展,护理工作的要求越来越高,护士的情绪劳动问题越来越突出.本文就护士情绪劳动问题的概念及表达、影响、相关因素以及管理干预策略展开综述,以期为解决护士情绪劳动问题、缓解护士心理压力、提高护理质量提供参考和支持.
This select group of Chengdu University of Traditional Chinese Medicine Affiliated Hospital of Gyne-cology postgraduate students as trainees,students complete the training and the use of standardized patients.By imple-menting this project,we trained the first batch of qualified school students standardized patient in TCM Gynecology, Gynecologic and explore and improve the standardized patient recruitment,training,management programs,combined with our own reality,to strengthen Chinese characteristics,improving our school gynecology teaching level.TCM Gyne-cology and student training and the use of standardized patients in difficulties we face and the experience gained are summarized discussed.
Objective To study the effect of two kinds of dosage forms on reducing blood lipid in hyperlipemia rats, the traditional pills and modern clinical decoctions were used for the treatment of hyperlipidemia model rats, respectively. Methods Hyperlipidemia rats induced by fat emulsion, meanwhile TC, TG, LDL and HDL in serum were measured by the enzymatic method. Additionally the expression of HMG-CoA, L-FABP gene in liver tissues was detected by real-time PCR. Results The levels of TC, TG and LDL in serum of the model group were significantly higher than those of the control group. Compared with the model control group, pills and decoctions could reduce the levels of indicators above all, which revealed a statistical significance ( P<0. 05 ) . Additionally the expression of HMG-CoA and L-FABP gene in livers of model control group were 20. 7 and 6. 33 times, respectively, as higher as that of the control group, which were notably decreased by 3. 28 and 39. 08 times after administration of pills compared with model control group, while after administration of decoctions these genes decreased by 3. 28 and 39. 08 times. Conclusion Coptis-Evodia herb couple in pills and decoctions can reduce blood lipid levels in hyperlipidemic rats and inhibit HMG-CoA and L-FABP gene expression. What’ s more, Coptis-Evodia herb couple in pills was much better than decoctions in gene inhibition. The survey indicated that Coptis-Evodia herb couple in pills was more advantageous and scientific.
咽,是人体经气流通之重地.观《内经》记载十二经脉中除手厥阴心包和足太阳膀胱经气是间接通于咽喉之外,其余十条经络皆直接通达于咽,故咽痛成为临床常见症,并作为主证或者兼证常出现在多种疾病过程中.《伤寒论》以三阴三阳为理论框架,在太阳、阳明、少阴、厥阴等篇章中重点论及了热证、寒证及寒热错杂证型中出现咽痛证治,显然仲景讨论咽痛意在以寒热为纲,表明虽六经病皆可致咽喉不利而痛,然寒热是其辨治关键.《伤寒论》中描述症状有"咽痛"、"咽中痛"、"咽中伤"、"喉咽不利"、"咽烂"等语,然其疼痛机制仍以寒凝或阳郁于咽喉、不通而痛为主.由于仲景扶阳思想其实是以人体阳气为本,包括保护阳气、资助阳气、调理阳气等多方面[1],故笔者认为仲景辨治咽痛之中亦包含着扶阳思想的广泛应用,现探讨于下.