目的:探讨补肾强血汤联合美多巴及普拉克索治疗帕金森病的疗效和安全性.方法:2014年9月-2015年9月收治帕金森病患者114例,随机数字表法分成两组各57例.对照组使用美多巴和普拉克索进行治疗,研究组在使用美多巴和普拉克索的基础上加用自拟方剂补肾强血汤.两组患者均连续用药12周,观察两组患者临床疗效,进行统一帕金森评定表(UPDRS)、Hoehn-Yahr分期、不良反应量表(TESS)、汉密顿抑郁量表(HAMD)评分.结果:研究组治疗后,HAMD评分明显高于对照组,差异有统计学意义(P＜0.05);研究组Hoehn-Yahr分期、UPDRS和TESS评分均明显低于对照组,差异有统计学意义(P＜0.05).结论:补肾强血汤联合美多巴及普拉克索治疗帕金森病具有良好的疗效,能够提高患者的治疗有效率,同时减少抑郁情绪和不良反应发生.

目的:探讨自拟补肾强血方治疗帕金森病的临床疗效.方法:将82例帕金森病患者随机分为两组各41例,对照组采用美多巴及盐酸司来吉兰治疗,治疗组在对照组基础上采用自拟补肾强血方治疗.观察两组患者治疗前后Webster评分、PD改良评分量表(UPDRS)评分系统、改良运动功能评分.结果:治疗组患者Webster改善率为64.92％,对照组患者Webster改善率为31.47％,治疗组疗效优于对照组(P＜0.05).治疗组患者治疗后UPDRS评分、运动功能评分均高于对照组(P＜0.05).结论:自拟补肾强血方治疗帕金森病疗效显著.

Objective It is to explore the curative effect of Chinese medicine differentiation combined western medicine on allergic purpura in children and the effect on immune globulin .Methods 104 cases of allergic purpura children were randomly divided into research group and the control group , each group had 52 cases.The research group was treated with Chinese med-icine differentiation combined with western medicine therapy , while the control group was given simple western medicine rou-tine treatment, The period of treatment was 4 weeks in both groups.The serum immunoglobulin (IgG, IgA) level and urinaly-sis before and after treatment were determined in both groups , the clinical curative effect and occurrences of side effects were observed , the recurrence of the two groups was followed up .Results The total effective rate of the researsh group was higher than that of the control group (P ＜0.05);There was no significant difference in the total effective rate of TCM syndrome a-mong every syndrome type in the research group (P＞0.05);The levels of serum IgA, IgG, RBC, WBC count, RBC, WBC high power field of vision , occult blood, urine protein distribution of the two groups after treatment were obviously improved (P＜0.05), and the improvements of the researsh group were better than that of control group (P＜0.05);There were no serious adverse reaction happened in the two groups;Followed up for 6 months, the recurrence rate of the research group was signifi-cantly lower than that of the control group ( P＜0.05).Conclusion Traditional Chinese medicine differentiation combined western medicine can significantly improve the clinical effect in treatment of allergic purpura in children , decrease the recur-rence rate, and has high security, its mechanism may be related to regulating immune globulin level , inhibiting the antigen-an-tibody reaction .

Objective To detect the level of TRANCE and BLys in serum of patients with anaphylactoid purpura.Methods The TRANCE and BLys level in serum of patients with anaphylactoid purpura were detected by ELISA(enzyme-linked immunosorbent assay,ELISA).Results TRANCE and BLys expression level in anaphylactoid purpura patients serum(2.83±0.96,90.48±2.64)were significantly higher than that in normal control groups(0.85±0.35,82.02±4.04)(P<0.01).TRANCE and BLys expression level in anaphylactoid purpura with kidney damage patients serum(4.09±0.45,93.92±2.07) were significantly higer than that in anaphylactoid purpura without kidney damage patients serum(2.44±0.70,89.42±1.75)(P<0.01).TRANCE and BLys expression level in anaphylactoid purpura patients serum was a significantly positive correlation(P<0.01).Conclusion TRANCE and BLys expression level in serum of patients with anaphylactoid purpura was higher,which may be involved in the formation of anaphylactoid purpura.

Objective To observe the effect of henoch-schonlein purpura(HSP) treated by therapy of integrated traditional and western medicine.Methods 200 patients with HSP were randomly divided into three groups.Chinese medicine group(n=45) was given Chinese medicine decoction.Control group(n=55) was given routine western medicine.100 cases in integrative Medicine with Western Medicine group were given therapy of integrated traditional and western medicine.The therapeutic course was seven days in three groups.The effect was evaluated after three courses.Results The mean platelet volume and platelet distribution width after treatment was decreased as compared with those before treatment in three groups(P0.05).Platelet hematocrit was increased as compared with that before treatment(P0.05).Mean platelet volume,platelet distribution width,platelet hematocrit can be used as reference for clinical evaluation.There was no significant difference between before and after treatment on prothrombin time(PT),thrombin time(TT) and activated partial thromboplastin time(KPTT) in 3 groups(P0.05).Conclusion The increase of mean platelet volume,platelet distribution width,platelet hematocrit was positively correlated with the incidence of the HSP.Platelets may be involved in the pathogenesis of HSP.Treating HSP by therapy of integrated traditional and western medicine is in line with HSP pathogenesis.The therapy of integrated traditional and western medicine Not only enhanced the therapeutic effect,and reduced side effects medicine.

<正>笔者采用五维甘草那敏胶囊联合中药治疗过敏性紫癜48例,并与五维甘草那敏胶囊进行对照观察,报告如下。1资料与方法1.1一般资料选取我院2009年10月至2010年10月门诊

玫瑰糠疹是一种常见的自限性炎症性皮肤病,中医学称为风癣.2007-12-2009-10,笔者应用五维甘草那敏胶囊联合中药治疗玫瑰糠疹100例,并与五维甘草那敏胶囊治疗96例对照观察,结果如下.

目的评价胺碘酮联合稳心颗粒与胺碘酮治疗急性心肌梗死(AMI)并室性心律失常的疗效和安全性。方法 204例AMI患者完全随机分为胺碘酮联合稳心颗粒组和胺碘酮组,每组102例。所有患者均按AMI常规处理,胺碘酮组予胺碘酮首剂150mg+0.9%氯化钠溶液20ml,10min内注入,间隔10～15min可重复,随后以1.0～1.5mg/min滴注维持6h,之后依病情减少剂量至0.5mg/min,直至仅出现偶发室性早搏,停止静脉给药,改口服胺碘酮600mg/d连续7d,此后改400mg/d连续7d,最后改为200mg/d维持治疗1个月,再减至200mg,1次/d,每周5d,间歇2d,维持6个月。胺碘酮联合稳心颗粒组在胺碘酮组治疗的基础上加服稳心颗粒,1袋(9g)/次,3次/d,维持6个月。结果胺碘酮联合稳心颗粒组,显效40例(39.2%),有效48例(47.1%),总有效率86.3%;胺碘酮组患者显效30例(29.9%),有效44例(43.1%),总有效率72.5%。2组差异有统计学意义(P<0.05)。无恶化病例,未出现严重不良反应。随访6个月未出现甲状腺功能异常及严重心律失常的发生。结论胺碘酮和稳心颗粒联合治疗AMI后室性心律失常效果满意,安全可靠,值得临床推广使用。

笔者自2006年2月至2007年6月,采用中西医结合治疗玫瑰糠疹,收到了满意的效果,现报道如下. 1 资料与方法 1.1 病例入选标准参照<临床皮肤病学>相关标准确诊.诊前1周未服用过抗病毒及免疫调节药物.

目的观察重组人干扰素α-2b凝胶外用泛昔洛韦口服联合中药水煎服治疗复发性生殖器疱疹的疗效。方法将58例复发性生殖器疱疹分为治疗组(重组人干扰素α-2b凝胶外用泛昔洛韦口服联合中药水煎服)30例;对照组(单纯采用西药治疗)28例作对照。结果治疗组有效率86.7%,而对照组有效率64.3%,两组总有效率比较差异有统计学意义(P<0.05)。结论中西药联合内服外用治疗复发性生殖器疱疹优于单纯应用西药治疗,值得临床应用及推广。

目的 观察四妙丸加味(白花蛇舌草、黄柏、苍术、牛夕、苦参、土茯苓、炒薏苡仁、防已、秦艽、炒麦芽、川楝子)治疗复发性生殖器疱疹的临床疗效.方法 将74例复发性生殖器疱疹分为治疗组37例,应用四妙丸加味进行治疗.对照组37例口服阿昔洛韦片口服.结果 治疗组总有效率78.4%,而对照组有效率35.1%.结论 四妙丸加味优于单纯应用阿昔洛韦口服治疗,提高了治愈率降低了复发频率,预示中医中药在治疗复发性生殖器疱疹方面有着广阔前景.

临床资料 患者男,26岁.因胸、腰背部皮下结节伴痛痒3个月余,于2008年12月5日来我科就诊.患者为我市一所"兰州拉面馆"厨师,半月前自青海老家来我市务工.

临床上多应用盐酸格拉司琼注射液治疗各种原因引起的呃逆,但由于盐酸格拉司琼注射液抑制肠蠕动,导致便秘,给患者带来极大的痛苦.2007-2008年,我们应用复方芦荟胶囊防治盐酸格拉司琼注射液所致便秘106例,结果如下.

生殖器疱疹(genifal herpes,GH)是一种常见的性传播疾病,其发病率呈逐年上升趋势,复发率高.2003-11-2006-11,笔者采用卡介菌多糖核酸联合中药治疗复发性生殖器疱疹60例,并与单纯应用卡介苗多糖核酸治疗28例对照观察,现报告如下.

我们于2005年6月～2007年6月,采用咪唑斯汀联合卡介菌多糖核酸,雷尼替丁治疗慢性荨麻疹112例,取得良好的效果,报道如下.

白癜风(vitligo)是一种常见的后天性色素性皮肤病,症状为皮肤出现局限性或泛发性色素脱失斑,直接影响到患者的外观容貌,给大部分患者的生活、学习、工作、交际等方面带来负面因素,从而影响了患者的生活质量.近年来一些新技术、新药物的出现给白癜风治疗带来了新的曙光.本文就白癜风的治疗进展做一综述.

<正>掌跖脓疱病是发生于掌跖部的一种慢性、复发性脓疱性皮肤病,笔者自2005年8月—2007年8月用中药治疗此病,效果满意,现报道如下。

为观察悸安冲剂Ⅰ治疗冠心病心律失常的临床疗效,将125例患者随机分成2组,均予肠溶阿斯匹林和丽珠欣乐治疗.治疗组(65例)在此基础上加用中药悸安冲剂,对照组(60例)加用心律平,疗程4周.结果:治疗组在改善心悸等各项临床症状方面明显优于对照组(P＜0.05;P＜0.01).提示悸安冲剂治疗冠心病心律失常有较好的疗效.

目的:观察脂调康胶囊对高脂血症(HLP)患者血清胆红素(TBil)的影响.方法:将186例HLP患者随机分为2组.治疗组124例口服脂调康胶囊(主要由橘络、清半夏、泽泻、丹参、姜黄、虎杖、炙黄芪、炒白术等组成),对照组62例口服脂必妥片.2组均以8周为1疗程.主要观察治疗前后血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、胆红素(TBil)等指标的变化.结果:2组治疗后TC、TG、LDL-C均较治疗前显著下降(P＜0.01),治疗组HDL-C显著增高(P＜0.01).2组治疗后比较,差异有非常显著性意义(P＜0.01).治疗组治疗后血清TBil含量较治疗前显著升高(P＜0.01),对照组治疗后亦较治疗前有所升高(P＜0.05).结论:脂调康胶囊通过升高HLP患者血清TBil的含量,抑制低密度脂蛋白氧化修饰,有效调节血脂,防止动脉粥样硬化等疾病的形成.